{"id":"https://openalex.org/W152752064","doi":"https://doi.org/10.1016/b978-0-12-187702-6.50053-0","title":"THE REDUCTIVE METABOLISM OF CARBON TETRACHLORIDE IN RECONSTITUTED MONOOXYGENASE SYSTEMS","display_name":"THE REDUCTIVE METABOLISM OF CARBON TETRACHLORIDE IN RECONSTITUTED MONOOXYGENASE SYSTEMS","publication_year":1980,"publication_date":"1980-01-01","ids":{"openalex":"https://openalex.org/W152752064","doi":"https://doi.org/10.1016/b978-0-12-187702-6.50053-0","mag":"152752064"},"language":"en","primary_location":{"id":"doi:10.1016/b978-0-12-187702-6.50053-0","doi":"https://doi.org/10.1016/b978-0-12-187702-6.50053-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-12-187702-6.50053-0","pdf_url":null,"source":{"id":"https://openalex.org/S2765034040","display_name":"Microsomes, Drug Oxidations and Chemical Carcinogenesis","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microsomes, Drug Oxidations and Chemical Carcinogenesis","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4300955625","display_name":"Microsomes, Drug Oxidations and Chemical Carcinogenesis"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5105406023","display_name":"R.M. Philpot","orcid":"https://orcid.org/0000-0001-9107-3034","observed_orcids":["https://orcid.org/0000-0001-9107-3034"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210095140","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Richard M. Philpot","raw_affiliation_strings":["Laboratory of Pharmacology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Pharmacology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072083165","display_name":"Wolfgang Nastainczyk","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210095140","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wolfgang M. Nastainczyk","raw_affiliation_strings":["Laboratory of Pharmacology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Pharmacology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5015414029","display_name":"Ronald Paul Mason","orcid":"https://orcid.org/0000-0002-1859-9109","observed_orcids":["https://orcid.org/0000-0002-1859-9109"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210095140","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ronald P. Mason","raw_affiliation_strings":["Laboratory of Pharmacology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Pharmacology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5087375405","display_name":"C. Roland Wolf","orcid":"https://orcid.org/0000-0002-6969-0113","observed_orcids":["https://orcid.org/0000-0002-6969-0113"]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4210095140","display_name":"National Institute of Environmental Health Sciences","ror":"https://ror.org/00j4k1h63","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"C. Roland Wolf","raw_affiliation_strings":["Laboratory of Pharmacology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Laboratory of Pharmacology, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4210095140"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.0306,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.66369048,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"877","last_page":"880"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.6187000274658203,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10375","display_name":"Pharmacogenetics and Drug Metabolism","score":0.6187000274658203,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11747","display_name":"Metal-Catalyzed Oxygenation Mechanisms","score":0.18459999561309814,"subfield":{"id":"https://openalex.org/subfields/1604","display_name":"Inorganic Chemistry"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T11465","display_name":"Drug-Induced Hepatotoxicity and Protection","score":0.13510000705718994,"subfield":{"id":"https://openalex.org/subfields/3004","display_name":"Pharmacology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/carbon-tetrachloride","display_name":"carbon tetrachloride","score":0.949999988079071},{"id":"https://openalex.org/keywords/chloroform-formation","display_name":"chloroform formation","score":0.8740000128746033},{"id":"https://openalex.org/keywords/cytochrome-p450","display_name":"cytochrome P450","score":0.9750000238418579},{"id":"https://openalex.org/keywords/lipid-peroxidation","display_name":"lipid peroxidation","score":0.8640000224113464},{"id":"https://openalex.org/keywords/trichloromethyl-radical","display_name":"trichloromethyl radical","score":0.9430000185966492},{"id":"https://openalex.org/keywords/free-radical-scavengers","display_name":"radical scavengers","score":0.9169999957084656}],"concepts":[{"id":"https://openalex.org/C2777359374","wikidata":"https://www.wikidata.org/wiki/Q225045","display_name":"Carbon tetrachloride","level":2,"score":0.9415518045425415},{"id":"https://openalex.org/C13002179","wikidata":"https://www.wikidata.org/wiki/Q6901821","display_name":"Monooxygenase","level":4,"score":0.7979879379272461},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.7526006102561951},{"id":"https://openalex.org/C2780829032","wikidata":"https://www.wikidata.org/wiki/Q898539","display_name":"Lipid peroxidation","level":3,"score":0.7387250065803528},{"id":"https://openalex.org/C2780768313","wikidata":"https://www.wikidata.org/wiki/Q408068","display_name":"Cytochrome","level":3,"score":0.6591240763664246},{"id":"https://openalex.org/C2781144210","wikidata":"https://www.wikidata.org/wiki/Q172275","display_name":"Chloroform","level":2,"score":0.6570707559585571},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.5767343044281006},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.5265384316444397},{"id":"https://openalex.org/C102124568","wikidata":"https://www.wikidata.org/wiki/Q5009626","display_name":"CCL4","level":3,"score":0.5057101249694824},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.41018468141555786},{"id":"https://openalex.org/C75473681","wikidata":"https://www.wikidata.org/wiki/Q188651","display_name":"Photochemistry","level":1,"score":0.407931923866272},{"id":"https://openalex.org/C526171541","wikidata":"https://www.wikidata.org/wiki/Q407693","display_name":"Cytochrome P450","level":3,"score":0.3989691138267517},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.35423147678375244}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/b978-0-12-187702-6.50053-0","doi":"https://doi.org/10.1016/b978-0-12-187702-6.50053-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-0-12-187702-6.50053-0","pdf_url":null,"source":{"id":"https://openalex.org/S2765034040","display_name":"Microsomes, Drug Oxidations and Chemical Carcinogenesis","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Microsomes, Drug Oxidations and Chemical Carcinogenesis","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[],"sustainable_development_goals_aurora":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":7,"referenced_works":["https://openalex.org/W1591925266","https://openalex.org/W1595582953","https://openalex.org/W1899938340","https://openalex.org/W1967235206","https://openalex.org/W2009086587","https://openalex.org/W2095788547","https://openalex.org/W2136531633"],"related_works":["https://openalex.org/W4406984770","https://openalex.org/W7097205219","https://openalex.org/W1838233329","https://openalex.org/W1982652418","https://openalex.org/W2021200077","https://openalex.org/W2064532182","https://openalex.org/W2058799578","https://openalex.org/W2087479566","https://openalex.org/W2012652819","https://openalex.org/W4232698178"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-10-17T09:40:24.721904","created_date":"2016-06-24T00:00:00"}