{"id":"https://openalex.org/W1525246191","doi":"https://doi.org/10.1002/9781118453926.ch10","title":"Neuronal Regulation of Bone Remodeling","display_name":"Neuronal Regulation of Bone Remodeling","publication_year":2013,"publication_date":"2013-07-19","ids":{"openalex":"https://openalex.org/W1525246191","doi":"https://doi.org/10.1002/9781118453926.ch10","mag":"1525246191"},"language":"en","primary_location":{"id":"doi:10.1002/9781118453926.ch10","doi":"https://doi.org/10.1002/9781118453926.ch10","is_oa":false,"landing_page_url":"https://doi.org/10.1002/9781118453926.ch10","pdf_url":null,"source":{"id":"https://openalex.org/S4306464293","display_name":"Wiley eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism","raw_type":"other"},"volume":{"id":"https://openalex.org/W3167589624","display_name":"Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism"},"type":"other","is_traditional":false,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5059211002","display_name":"Florent Elefteriou","orcid":"https://orcid.org/0000-0002-2972-5633","observed_orcids":["https://orcid.org/0000-0002-2972-5633"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Florent Elefteriou","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5086824931","display_name":"G\u00e9rard Karsenty","orcid":"https://orcid.org/0000-0002-9253-7627","observed_orcids":["https://orcid.org/0000-0002-9253-7627","https://orcid.org/0000-0002-9047-3332"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gerard Karsenty","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":10,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"82","last_page":"89"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11219","display_name":"Bone Metabolism and Diseases","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.002899999963119626,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10489","display_name":"Regulation of Appetite and Obesity","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2807","display_name":"Endocrine and Autonomic Systems"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/bone-remodeling","display_name":"bone remodeling","score":0.9990000128746033},{"id":"https://openalex.org/keywords/hypothalamus","display_name":"hypothalamus","score":0.8230000138282776},{"id":"https://openalex.org/keywords/brainstem-neurons","display_name":"brainstem neurons","score":0.8399999737739563},{"id":"https://openalex.org/keywords/cocaine-and-amphetamine-regulated-transcript","display_name":"cocaine- and amphetamine-regulated transcript","score":0.8989999890327454},{"id":"https://openalex.org/keywords/cart","display_name":"CART","score":0.6809999942779541},{"id":"https://openalex.org/keywords/osteoblasts","display_name":"osteoblasts","score":0.8389999866485596},{"id":"https://openalex.org/keywords/osteoclasts","display_name":"osteoclasts","score":1.0},{"id":"https://openalex.org/keywords/sympathetic-nervous-system","display_name":"sympathetic nervous system","score":0.996999979019165},{"id":"https://openalex.org/keywords/parasympathetic-nervous-system","display_name":"parasympathetic nervous system","score":0.9980000257492065},{"id":"https://openalex.org/keywords/autonomic-nervous-system","display_name":"autonomic nervous system","score":0.8619999885559082},{"id":"https://openalex.org/keywords/bone-homeostasis","display_name":"bone homeostasis","score":0.9359999895095825}],"concepts":[{"id":"https://openalex.org/C170033053","wikidata":"https://www.wikidata.org/wiki/Q952019","display_name":"Bone remodeling","level":2,"score":0.7698203921318054},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.4511985182762146},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3385124206542969},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.13286641240119934}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1002/9781118453926.ch10","doi":"https://doi.org/10.1002/9781118453926.ch10","is_oa":false,"landing_page_url":"https://doi.org/10.1002/9781118453926.ch10","pdf_url":null,"source":{"id":"https://openalex.org/S4306464293","display_name":"Wiley eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Primer on the Metabolic Bone Diseases and Disorders of Mineral Metabolism","raw_type":"other"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.428600013256073}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":70,"referenced_works":["https://openalex.org/W30545629","https://openalex.org/W1490643348","https://openalex.org/W1600064425","https://openalex.org/W1963690512","https://openalex.org/W1970728706","https://openalex.org/W1970892611","https://openalex.org/W1975260205","https://openalex.org/W1979448723","https://openalex.org/W1982945600","https://openalex.org/W1983171921","https://openalex.org/W1984548515","https://openalex.org/W1986123865","https://openalex.org/W1990210398","https://openalex.org/W1994829213","https://openalex.org/W1997508587","https://openalex.org/W2001246671","https://openalex.org/W2005469249","https://openalex.org/W2005487416","https://openalex.org/W2007783033","https://openalex.org/W2010079727","https://openalex.org/W2010226911","https://openalex.org/W2011766130","https://openalex.org/W2012800209","https://openalex.org/W2020911258","https://openalex.org/W2025079451","https://openalex.org/W2026982802","https://openalex.org/W2031500012","https://openalex.org/W2034121143","https://openalex.org/W2039260429","https://openalex.org/W2042696146","https://openalex.org/W2043303731","https://openalex.org/W2046327104","https://openalex.org/W2046396082","https://openalex.org/W2047545003","https://openalex.org/W2051560210","https://openalex.org/W2054756476","https://openalex.org/W2058919126","https://openalex.org/W2060955024","https://openalex.org/W2066856138","https://openalex.org/W2067989307","https://openalex.org/W2071823872","https://openalex.org/W2081758121","https://openalex.org/W2083279848","https://openalex.org/W2087706354","https://openalex.org/W2090973045","https://openalex.org/W2094986449","https://openalex.org/W2100450635","https://openalex.org/W2112561547","https://openalex.org/W2114589447","https://openalex.org/W2121497606","https://openalex.org/W2125354005","https://openalex.org/W2129722309","https://openalex.org/W2131996102","https://openalex.org/W2136163260","https://openalex.org/W2146727923","https://openalex.org/W2147510409","https://openalex.org/W2149211697","https://openalex.org/W2152283790","https://openalex.org/W2152615219","https://openalex.org/W2153275137","https://openalex.org/W2156972609","https://openalex.org/W2159392554","https://openalex.org/W2159921044","https://openalex.org/W2165884167","https://openalex.org/W2167160331","https://openalex.org/W2167442670","https://openalex.org/W2172110216","https://openalex.org/W2317060418","https://openalex.org/W2404932304","https://openalex.org/W2463786168"],"related_works":["https://openalex.org/W1548111728","https://openalex.org/W2113010384","https://openalex.org/W56754421","https://openalex.org/W2046882967","https://openalex.org/W4246060400","https://openalex.org/W1963686806","https://openalex.org/W2176228859","https://openalex.org/W2767834969","https://openalex.org/W1938752929","https://openalex.org/W7155044671"],"abstract_inverted_index":{"Bone":[0],"remodeling,":[1],"the":[2,19,22,33,42,73,100,106,113,116,120,124,129],"process":[3],"whereby":[4,36],"bone":[5,26,70,94,109,137],"is":[6,11,79],"constantly":[7],"renewed":[8],"during":[9],"adulthood,":[10],"a":[12],"prototypical":[13],"homeostatic":[14],"process.":[15],"This":[16],"chapter":[17],"discusses":[18],"mechanisms":[20],"underlying":[21],"central":[23],"control":[24],"of":[25,32,44,62,76,99,108,115,123],"mass":[27],"in":[28,68,105,136],"detail.":[29],"The":[30,60,96],"nature":[31,75],"downstream":[34],"mechanism":[35],"brainstem":[37],"and":[38,50,57,64,72,92,128],"hypothalamic":[39,74,89],"neurons":[40],"regulate":[41],"activity":[43],"distant":[45],"cells,":[46],"such":[47],"as":[48],"osteoblasts":[49],"osteoclasts,":[51],"has":[52],"been":[53],"determined":[54],"through":[55],"genetic":[56],"pharmacological":[58],"approaches.":[59],"importance":[61],"cocaine":[63],"amphetamine-regulated":[65],"transcript":[66],"(CART)":[67],"regulating":[69],"remodeling":[71,110],"this":[77],"regulation":[78,107],"supported":[80],"by":[81,85],"animal":[82],"models":[83],"characterized":[84],"low":[86],"or":[87],"high":[88],"Cart":[90],"expression":[91],"significant":[93],"phenotypes.":[95],"crucial":[97],"role":[98,118],"sympathetic":[101],"nervous":[102,126,131],"system":[103,127,132],"(SNS)":[104],"leads":[111],"to":[112],"question":[114],"possible":[117],"that":[119],"other":[121],"arm":[122],"autonomic":[125],"parasympathetic":[130],"(PNS)":[133],"may":[134],"have":[135],"remodeling.":[138]},"counts_by_year":[{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}
