{"id":"https://openalex.org/W1524901905","doi":"https://doi.org/10.1002/j.1460-2075.1988.tb02867.x","title":"Molecular cloning of the human B cell CD20 receptor predicts a hydrophobic protein with multiple transmembrane domains.","display_name":"Molecular cloning of the human B cell CD20 receptor predicts a hydrophobic protein with multiple transmembrane domains.","publication_year":1988,"publication_date":"1988-03-01","ids":{"openalex":"https://openalex.org/W1524901905","doi":"https://doi.org/10.1002/j.1460-2075.1988.tb02867.x","mag":"1524901905","pmid":"https://pubmed.ncbi.nlm.nih.gov/2456210","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/454379"},"language":"en","primary_location":{"id":"doi:10.1002/j.1460-2075.1988.tb02867.x","doi":"https://doi.org/10.1002/j.1460-2075.1988.tb02867.x","is_oa":true,"landing_page_url":"https://doi.org/10.1002/j.1460-2075.1988.tb02867.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/j.1460-2075.1988.tb02867.x","source":{"id":"https://openalex.org/S127916151","display_name":"The EMBO Journal","issn_l":"0261-4189","issn":["0261-4189","1460-2075"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/j.1460-2075.1988.tb02867.x","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5064538728","display_name":"David A. Einfeld","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"D. A. Einfeld","raw_affiliation_strings":["ONCOGEN, Seattle, WA 98121"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ONCOGEN, Seattle, WA 98121","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113604897","display_name":"JOSEPH PATRICK BROWN","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. P. Brown","raw_affiliation_strings":["ONCOGEN, Seattle, WA 98121"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ONCOGEN, Seattle, WA 98121","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5039580182","display_name":"Mary A. Valentine","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. A. Valentine","raw_affiliation_strings":["ONCOGEN, Seattle, WA 98121"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ONCOGEN, Seattle, WA 98121","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5004809714","display_name":"Edward A. Clark","orcid":"https://orcid.org/0000-0001-8061-5475","observed_orcids":["https://orcid.org/0000-0001-8061-5475"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"E. A. Clark","raw_affiliation_strings":["ONCOGEN, Seattle, WA 98121"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ONCOGEN, Seattle, WA 98121","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108555189","display_name":"Jeffrey A. Ledbetter","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J. A. Ledbetter","raw_affiliation_strings":["ONCOGEN, Seattle, WA 98121"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"ONCOGEN, Seattle, WA 98121","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":7990,"currency":"USD","value_usd":7990},"apc_paid":null,"fwci":2.6286,"has_fulltext":true,"cited_by_count":279,"citation_normalized_percentile":{"value":0.90064149,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":92,"max":99},"biblio":{"volume":"7","issue":"3","first_page":"711","last_page":"717"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.9765999913215637,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.003800000064074993,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11016","display_name":"Monoclonal and Polyclonal Antibodies Research","score":0.00279999990016222,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cd20","display_name":"CD20","score":0.9620000123977661},{"id":"https://openalex.org/keywords/b-cell-receptor","display_name":"B cell receptor","score":0.8989999890327454},{"id":"https://openalex.org/keywords/cdna-cloning","display_name":"cDNA cloning","score":0.7649999856948853},{"id":"https://openalex.org/keywords/transmembrane-proteins","display_name":"transmembrane proteins","score":0.6890000104904175},{"id":"https://openalex.org/keywords/alternative-splicing","display_name":"alternative splicing","score":0.949999988079071},{"id":"https://openalex.org/keywords/transcript-isoforms","display_name":"mRNA isoforms","score":0.6830000281333923},{"id":"https://openalex.org/keywords/hydrophobic-domains","display_name":"hydrophobic domains","score":0.703000009059906},{"id":"https://openalex.org/keywords/b-cell-activation","display_name":"B cell activation","score":0.75},{"id":"https://openalex.org/keywords/cd40-activation","display_name":"CD40 stimulation","score":0.8389999866485596},{"id":"https://openalex.org/keywords/protein-phosphorylation","display_name":"protein phosphorylation","score":0.9160000085830688},{"id":"https://openalex.org/keywords/protein-kinases","display_name":"protein kinases","score":0.5960000157356262}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5246037244796753},{"id":"https://openalex.org/C24530287","wikidata":"https://www.wikidata.org/wiki/Q424204","display_name":"Transmembrane protein","level":3,"score":0.4442563056945801},{"id":"https://openalex.org/C161191863","wikidata":"https://www.wikidata.org/wiki/Q199655","display_name":"Library science","level":1,"score":0.34796929359436035},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.26503661274909973},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.18544894456863403},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.09158816933631897}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000944","descriptor_name":"Antigens, Differentiation, B-Lymphocyte","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001402","descriptor_name":"B-Lymphocytes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003001","descriptor_name":"Cloning, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000302","qualifier_name":"isolation & purification","is_major_topic":true},{"descriptor_ui":"D008958","descriptor_name":"Models, Molecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008968","descriptor_name":"Molecular Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011956","descriptor_name":"Receptors, Cell Surface","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D011956","descriptor_name":"Receptors, Cell Surface","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018951","descriptor_name":"Antigens, CD20","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1002/j.1460-2075.1988.tb02867.x","doi":"https://doi.org/10.1002/j.1460-2075.1988.tb02867.x","is_oa":true,"landing_page_url":"https://doi.org/10.1002/j.1460-2075.1988.tb02867.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/j.1460-2075.1988.tb02867.x","source":{"id":"https://openalex.org/S127916151","display_name":"The EMBO Journal","issn_l":"0261-4189","issn":["0261-4189","1460-2075"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO Journal","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:454379","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/454379","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EMBO J","raw_type":"Text"},{"id":"pmid:2456210","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2456210","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO journal","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1002/j.1460-2075.1988.tb02867.x","doi":"https://doi.org/10.1002/j.1460-2075.1988.tb02867.x","is_oa":true,"landing_page_url":"https://doi.org/10.1002/j.1460-2075.1988.tb02867.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1002/j.1460-2075.1988.tb02867.x","source":{"id":"https://openalex.org/S127916151","display_name":"The EMBO Journal","issn_l":"0261-4189","issn":["0261-4189","1460-2075"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO Journal","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G6246653509","display_name":"Structural/Function B Cell Differentiation Antigens","funder_award_id":"R01GM037905","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G6952987319","display_name":"National Primate Research Center","funder_award_id":"P51RR000166","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G9000097005","display_name":null,"funder_award_id":"RR00166","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1524901905.pdf","grobid_xml":"https://content.openalex.org/works/W1524901905.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W1484262719","https://openalex.org/W1484629663","https://openalex.org/W1513717105","https://openalex.org/W1522410151","https://openalex.org/W1574744856","https://openalex.org/W1597225811","https://openalex.org/W1809924897","https://openalex.org/W1814273895","https://openalex.org/W1913508491","https://openalex.org/W1929194579","https://openalex.org/W1971344463","https://openalex.org/W1971823291","https://openalex.org/W1972961295","https://openalex.org/W1975304761","https://openalex.org/W1975645575","https://openalex.org/W1996916918","https://openalex.org/W2003606976","https://openalex.org/W2008936546","https://openalex.org/W2009105413","https://openalex.org/W2012847227","https://openalex.org/W2019433452","https://openalex.org/W2022623654","https://openalex.org/W2024696435","https://openalex.org/W2025450446","https://openalex.org/W2027092642","https://openalex.org/W2028622989","https://openalex.org/W2039427220","https://openalex.org/W2045862009","https://openalex.org/W2045961778","https://openalex.org/W2048669565","https://openalex.org/W2050432242","https://openalex.org/W2054468433","https://openalex.org/W2067130241","https://openalex.org/W2074783201","https://openalex.org/W2094362927","https://openalex.org/W2117486036","https://openalex.org/W2138270253","https://openalex.org/W2142526109","https://openalex.org/W2161620889","https://openalex.org/W2173963963","https://openalex.org/W6629202933","https://openalex.org/W6680551228","https://openalex.org/W6733143093"],"related_works":["https://openalex.org/W2153484735","https://openalex.org/W1974283070","https://openalex.org/W1633090059","https://openalex.org/W4233546615","https://openalex.org/W2585195725","https://openalex.org/W2155725804","https://openalex.org/W2113311041","https://openalex.org/W2993728536","https://openalex.org/W1983339176","https://openalex.org/W1573856597"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":5},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":7},{"year":2015,"cited_by_count":7},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":10},{"year":2012,"cited_by_count":8}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}