{"id":"https://openalex.org/W1522940754","doi":"https://doi.org/10.1128/jvi.29.1.76-82.1979","title":"\u201csarc\u201d Sequence Transcription in Moloney Sarcoma Virus-Transformed Nonproducer Cell Lines","display_name":"\u201csarc\u201d Sequence Transcription in Moloney Sarcoma Virus-Transformed Nonproducer Cell Lines","publication_year":1979,"publication_date":"1979-01-01","ids":{"openalex":"https://openalex.org/W1522940754","doi":"https://doi.org/10.1128/jvi.29.1.76-82.1979","mag":"1522940754","pmid":"https://pubmed.ncbi.nlm.nih.gov/430602","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/353076"},"language":"en","primary_location":{"id":"doi:10.1128/jvi.29.1.76-82.1979","doi":"https://doi.org/10.1128/jvi.29.1.76-82.1979","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jvi.29.1.76-82.1979","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/353076","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113672138","display_name":"Maurice C. Bondurant","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47838141","display_name":"Saint Louis University","ror":"https://ror.org/01p7jjy08","country_code":"US","type":"education","lineage":["https://openalex.org/I47838141"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maurice Bondurant","raw_affiliation_strings":["Institute for Molecular Virology, Saint Louis University School of Medicine, St. Louis, Missouri 63110"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Molecular Virology, Saint Louis University School of Medicine, St. Louis, Missouri 63110","institution_ids":["https://openalex.org/I47838141"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5074905239","display_name":"Rajani Ramabhadran","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47838141","display_name":"Saint Louis University","ror":"https://ror.org/01p7jjy08","country_code":"US","type":"education","lineage":["https://openalex.org/I47838141"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rajani Ramabhadran","raw_affiliation_strings":["Institute for Molecular Virology, Saint Louis University School of Medicine, St. Louis, Missouri 63110"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Molecular Virology, Saint Louis University School of Medicine, St. Louis, Missouri 63110","institution_ids":["https://openalex.org/I47838141"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103398972","display_name":"Maurice Green","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47838141","display_name":"Saint Louis University","ror":"https://ror.org/01p7jjy08","country_code":"US","type":"education","lineage":["https://openalex.org/I47838141"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Maurice Green","raw_affiliation_strings":["Institute for Molecular Virology, Saint Louis University School of Medicine, St. Louis, Missouri 63110"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Molecular Virology, Saint Louis University School of Medicine, St. Louis, Missouri 63110","institution_ids":["https://openalex.org/I47838141"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5032387026","display_name":"William S.M. Wold","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I47838141","display_name":"Saint Louis University","ror":"https://ror.org/01p7jjy08","country_code":"US","type":"education","lineage":["https://openalex.org/I47838141"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William S. M. Wold","raw_affiliation_strings":["Institute for Molecular Virology, Saint Louis University School of Medicine, St. Louis, Missouri 63110"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute for Molecular Virology, Saint Louis University School of Medicine, St. Louis, Missouri 63110","institution_ids":["https://openalex.org/I47838141"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I47838141"],"apc_list":null,"apc_paid":null,"fwci":0.3795,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.54334814,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"29","issue":"1","first_page":"76","last_page":"82"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies","score":0.9976000189781189,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10521","display_name":"RNA and protein synthesis mechanisms","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/moloney-murine-sarcoma-virus","display_name":"Moloney murine sarcoma virus","score":0.8420000076293945},{"id":"https://openalex.org/keywords/superinfection","display_name":"superinfection","score":0.7689999938011169},{"id":"https://openalex.org/keywords/moloney-murine-leukemia-virus","display_name":"Moloney murine leukemia virus","score":0.875},{"id":"https://openalex.org/keywords/proviral-dna","display_name":"proviral DNA","score":0.44999998807907104}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9755582809448242},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.6868381500244141},{"id":"https://openalex.org/C179926584","wikidata":"https://www.wikidata.org/wiki/Q207714","display_name":"Transcription (linguistics)","level":2,"score":0.49148499965667725},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.47925829887390137},{"id":"https://openalex.org/C2778112365","wikidata":"https://www.wikidata.org/wiki/Q3511065","display_name":"Sequence (biology)","level":2,"score":0.46683111786842346},{"id":"https://openalex.org/C2776130206","wikidata":"https://www.wikidata.org/wiki/Q636512","display_name":"Gammaretrovirus","level":4,"score":0.428687185049057},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.33940839767456055},{"id":"https://openalex.org/C2779562191","wikidata":"https://www.wikidata.org/wiki/Q673848","display_name":"Murine leukemia virus","level":3,"score":0.2464405596256256},{"id":"https://openalex.org/C138885662","wikidata":"https://www.wikidata.org/wiki/Q5891","display_name":"Philosophy","level":0,"score":0.0},{"id":"https://openalex.org/C41895202","wikidata":"https://www.wikidata.org/wiki/Q8162","display_name":"Linguistics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002472","descriptor_name":"Cell Transformation, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D002999","descriptor_name":"Clone Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D004247","descriptor_name":"DNA","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D005814","descriptor_name":"Genes, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D008979","descriptor_name":"Moloney murine leukemia virus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D008979","descriptor_name":"Moloney murine leukemia virus","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009693","descriptor_name":"Nucleic Acid Hybridization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012367","descriptor_name":"RNA, Viral","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1128/jvi.29.1.76-82.1979","doi":"https://doi.org/10.1128/jvi.29.1.76-82.1979","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jvi.29.1.76-82.1979","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:353076","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/353076","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Virol","raw_type":"Text"},{"id":"pmid:430602","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/430602","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of virology","raw_type":"Journal Article"}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:353076","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/353076","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Virol","raw_type":"Text"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":29,"referenced_works":["https://openalex.org/W1456663196","https://openalex.org/W1530713555","https://openalex.org/W1581662425","https://openalex.org/W1582605621","https://openalex.org/W1587981028","https://openalex.org/W1783191367","https://openalex.org/W1820037638","https://openalex.org/W1843043480","https://openalex.org/W1967134681","https://openalex.org/W1968598595","https://openalex.org/W1979412344","https://openalex.org/W1979471995","https://openalex.org/W1980499092","https://openalex.org/W1983612412","https://openalex.org/W1987656535","https://openalex.org/W1998290353","https://openalex.org/W1998927596","https://openalex.org/W2002581213","https://openalex.org/W2004318136","https://openalex.org/W2014015430","https://openalex.org/W2015121030","https://openalex.org/W2016351483","https://openalex.org/W2016638271","https://openalex.org/W2017638565","https://openalex.org/W2066053076","https://openalex.org/W2070901450","https://openalex.org/W2083715166","https://openalex.org/W2115280257","https://openalex.org/W2255481267"],"related_works":["https://openalex.org/W1820037638","https://openalex.org/W1998927596","https://openalex.org/W2094467855","https://openalex.org/W1981327220","https://openalex.org/W1975395219","https://openalex.org/W1769059889","https://openalex.org/W1958265700","https://openalex.org/W7097345025","https://openalex.org/W1977239142","https://openalex.org/W1994563830"],"abstract_inverted_index":{"(3)H-labeled":[0,193],"complementary":[1,3,194],"DNA(sarc),":[2],"to":[4,53,214],"the":[5,12,25,51,85,110,115,129,132,141,147,154,184,188,201,207,220],"murine":[6,62,175],"sarcoma":[7],"virus":[8,177],"(MSV)-specific":[9],"portion":[10],"of":[11,27,87,96,103,122,134,144,146,166,203,245,257,262],"Moloney":[13,61,174],"MSV":[14],"(M-MSV)":[15],"genome,":[16],"was":[17,21,210],"prepared.":[18],"M-MSV-specific":[19,204],"RNA":[20,65,137,186,205,236],"then":[22],"quantitated":[23],"in":[24,109,179,183,187,206,219,230,234,265],"cytoplasm":[26],"several":[28],"M-MSV-transformed,":[29],"non-virus-producing,":[30],"clonal":[31],"NIH":[32,117],"3T3":[33,118],"cell":[34,88,148,189,221,270],"lines.":[35,164],"These":[36],"lines,":[37,149],"designated":[38],"71":[39],"N":[40],"clones":[41,224],"5,":[42],"6,":[43],"and":[44,59,68,77,90,120,159,226,233,269],"3,":[45],"have":[46],"been":[47],"characterized":[48],"previously":[49],"by":[50,92],"degree":[52],"which":[54],"they":[55,113,238],"exhibit":[56],"transformation":[57,145,231],"properties":[58],"transcribe":[60],"leukemia":[63,176],"virus-related":[64],"(S.":[66],"Salzberg":[67],"M.":[69,78],"Green,":[70,79],"J.":[71,80],"Virol.":[72,81],"13:1001-1004,":[73],"1974;":[74],"N.":[75],"Tsuchida":[76],"14:587-591,":[82],"1974).":[83],"By":[84],"criteria":[86],"morphology":[89],"agglutination":[91],"concanavalin":[93],"A,":[94],"cells":[95,102,121],"clone":[97,104,123,168,171],"5":[98,169,225],"are":[99,106,125],"highly":[100],"transformed,":[101],"6":[105,172,227],"almost":[107],"normal":[108],"sense":[111],"that":[112,200],"resemble":[114],"parent":[116],"cells,":[119],"3":[124],"phenotypically":[126],"intermediate.":[127],"In":[128],"present":[130],"study,":[131],"amounts":[133],"cytoplasmic":[135],"MSV-specific":[136,185,235,246],"correlated":[138],"well":[139],"with":[140,173],"relative":[142],"degrees":[143],"varying":[150],"over":[151],"35-fold":[152],"between":[153],"least":[155],"transformed":[156,161],"(clone":[157,162],"6)":[158],"most":[160],"5)":[163],"Superinfection":[165],"either":[167],"or":[170],"resulted":[178],"a":[180],"fivefold":[181],"increase":[182],"cytoplasm.":[190],"Evidence":[191],"from":[192],"DNA:cell":[195],"DNA":[196,215,247],"hybridization":[197],"studies":[198],"indicated":[199],"quantity":[202],"nonproducer":[208],"lines":[209],"not":[211],"directly":[212],"related":[213],"provirus":[216,258],"copy":[217],"number":[218],"DNA.":[222],"Although":[223],"differ":[228],"greatly":[229],"characteristics":[232],"content,":[237],"each":[239],"apparently":[240],"contain":[241],"about":[242],"two":[243],"copies":[244],"sequence":[248],"per":[249],"haploid":[250],"genome.":[251],"Thus,":[252],"factors":[253],"such":[254],"as":[255],"site":[256],"integration":[259],"may":[260],"be":[261],"primary":[263],"importance":[264],"determining":[266],"virus-specific":[267],"transcription":[268],"transformation.":[271]},"counts_by_year":[],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}