{"id":"https://openalex.org/W1522677201","doi":null,"title":"Antipsic\u00f3tico t\u00edpico produz efeitos amn\u00e9sicos pelo bloqueio de receptores D2 p\u00f3s-sin\u00e1pticos no estriado dorsolateral de ratos, mas n\u00e3o afeta a dessensibiliza\u00e7\u00e3o de receptores D2 pr\u00e9-sin\u00e1pticos no n\u00facleo accubens em modelo animal de esquizofrenia","display_name":"Antipsic\u00f3tico t\u00edpico produz efeitos amn\u00e9sicos pelo bloqueio de receptores D2 p\u00f3s-sin\u00e1pticos no estriado dorsolateral de ratos, mas n\u00e3o afeta a dessensibiliza\u00e7\u00e3o de receptores D2 pr\u00e9-sin\u00e1pticos no n\u00facleo accubens em modelo animal de esquizofrenia","publication_year":2015,"publication_date":"2015-01-01","ids":{"openalex":"https://openalex.org/W1522677201","mag":"1522677201"},"language":"pt","primary_location":{"id":"pmh:oai:acervodigital.ufpr.br:1884/37360","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1884/37360","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"instacron:UFPR","raw_type":"info:eu-repo/semantics/doctoralThesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/1884/37360","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005799637","display_name":"Suelen Lucio Boschen","orcid":"https://orcid.org/0000-0002-7694-920X","observed_orcids":["https://orcid.org/0000-0002-7694-920X"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Suelen L. Boschen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5005799637"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.6596999764442444,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10023","display_name":"Schizophrenia research and treatment","score":0.6596999764442444,"subfield":{"id":"https://openalex.org/subfields/2738","display_name":"Psychiatry and Mental health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.32519999146461487,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.006399999838322401,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/typical-antipsychotics","display_name":"typical antipsychotics","score":0.9670000076293945},{"id":"https://openalex.org/keywords/amnesia","display_name":"amnesia","score":0.6510000228881836},{"id":"https://openalex.org/keywords/dopamine-d2-receptor-blockade","display_name":"dopamine D2 receptor blockade","score":0.8019999861717224},{"id":"https://openalex.org/keywords/dorsolateral-striatum","display_name":"dorsolateral striatum","score":0.8889999985694885},{"id":"https://openalex.org/keywords/nucleus-accumbens","display_name":"nucleus accumbens","score":0.9079999923706055},{"id":"https://openalex.org/keywords/receptor-desensitization","display_name":"receptor desensitization","score":0.9070000052452087},{"id":"https://openalex.org/keywords/animal-models-of-schizophrenia","display_name":"animal models of schizophrenia","score":0.8159999847412109},{"id":"https://openalex.org/keywords/rats","display_name":"rats","score":0.7670000195503235}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.35346919298171997},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3386740982532501}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:acervodigital.ufpr.br:1884/37360","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1884/37360","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"instacron:UFPR","raw_type":"info:eu-repo/semantics/doctoralThesis"},{"id":"mag:1522677201","doi":null,"is_oa":false,"landing_page_url":"https://acervodigital.ufpr.br/bitstream/1884/37360/3/R%20-%20T%20-%20SUELEN%20LUCIO%20BOSCHEN.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:acervodigital.ufpr.br:1884/37360","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/1884/37360","pdf_url":null,"source":{"id":"https://openalex.org/S4306402641","display_name":"LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Cient\u00edficas)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4383465926","host_organization_name":"LA Referencia","host_organization_lineage":["https://openalex.org/I4383465926"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"instacron:UFPR","raw_type":"info:eu-repo/semantics/doctoralThesis"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8371999859809875}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321091","display_name":"Coordena\u00e7\u00e3o de Aperfei\u00e7oamento de Pessoal de N\u00edvel Superior","ror":"https://ror.org/00x0ma614"},{"id":"https://openalex.org/F4320322025","display_name":"Conselho Nacional de Desenvolvimento Cient\u00edfico e Tecnol\u00f3gico","ror":"https://ror.org/03swz6y49"},{"id":"https://openalex.org/F4320322772","display_name":"Funda\u00e7\u00e3o Arauc\u00e1ria","ror":"https://ror.org/02r7nkw81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":121,"referenced_works":["https://openalex.org/W1529770635","https://openalex.org/W1546116904","https://openalex.org/W1577984325","https://openalex.org/W1579117675","https://openalex.org/W1624116415","https://openalex.org/W1633847368","https://openalex.org/W1764194029","https://openalex.org/W1819218275","https://openalex.org/W1891034379","https://openalex.org/W1925492557","https://openalex.org/W1949404224","https://openalex.org/W1966092598","https://openalex.org/W1966233483","https://openalex.org/W1969574672","https://openalex.org/W1970892722","https://openalex.org/W1972498750","https://openalex.org/W1972815121","https://openalex.org/W1977869470","https://openalex.org/W1978615503","https://openalex.org/W1978674818","https://openalex.org/W1978826091","https://openalex.org/W1982827121","https://openalex.org/W1984315717","https://openalex.org/W1984785177","https://openalex.org/W1985422218","https://openalex.org/W1987934874","https://openalex.org/W1991603311","https://openalex.org/W1992654377","https://openalex.org/W1993833941","https://openalex.org/W1996210781","https://openalex.org/W1997255267","https://openalex.org/W1998489561","https://openalex.org/W2000818014","https://openalex.org/W2000858615","https://openalex.org/W2001529605","https://openalex.org/W2005293058","https://openalex.org/W2006706959","https://openalex.org/W2015465857","https://openalex.org/W2017559332","https://openalex.org/W2019546178","https://openalex.org/W2022633426","https://openalex.org/W2024365408","https://openalex.org/W2024486693","https://openalex.org/W2029007897","https://openalex.org/W2031337229","https://openalex.org/W2031865881","https://openalex.org/W2032223397","https://openalex.org/W2032295207","https://openalex.org/W2033284293","https://openalex.org/W2034457280","https://openalex.org/W2035501864","https://openalex.org/W2038409107","https://openalex.org/W2039014242","https://openalex.org/W2039482493","https://openalex.org/W2041068326","https://openalex.org/W2041586430","https://openalex.org/W2042572088","https://openalex.org/W2042914870","https://openalex.org/W2044827761","https://openalex.org/W2047015502","https://openalex.org/W2047100324","https://openalex.org/W2048982528","https://openalex.org/W2050947811","https://openalex.org/W2053670970","https://openalex.org/W2055744411","https://openalex.org/W2058077554","https://openalex.org/W2058955351","https://openalex.org/W2060588252","https://openalex.org/W2060802427","https://openalex.org/W2064085644","https://openalex.org/W2068057735","https://openalex.org/W2070888840","https://openalex.org/W2073845471","https://openalex.org/W2083042885","https://openalex.org/W2085360366","https://openalex.org/W2086015992","https://openalex.org/W2086779090","https://openalex.org/W2088354267","https://openalex.org/W2088495343","https://openalex.org/W2090830849","https://openalex.org/W2091207632","https://openalex.org/W2092462980","https://openalex.org/W2092636839","https://openalex.org/W2093898284","https://openalex.org/W2094569095","https://openalex.org/W2095088925","https://openalex.org/W2098342476","https://openalex.org/W2099652807","https://openalex.org/W2106953101","https://openalex.org/W2111993699","https://openalex.org/W2116663526","https://openalex.org/W2119369900","https://openalex.org/W2133709709","https://openalex.org/W2134807533","https://openalex.org/W2137888806","https://openalex.org/W2139387001","https://openalex.org/W2141716990","https://openalex.org/W2144011990","https://openalex.org/W2144534164","https://openalex.org/W2145602532","https://openalex.org/W2146545384","https://openalex.org/W2152976206","https://openalex.org/W2153144026","https://openalex.org/W2153325732","https://openalex.org/W2155694557","https://openalex.org/W2157420527","https://openalex.org/W2157844171","https://openalex.org/W2157872494","https://openalex.org/W2158284822","https://openalex.org/W2160330420","https://openalex.org/W2164830115","https://openalex.org/W2165387222","https://openalex.org/W2165451664","https://openalex.org/W2165843693","https://openalex.org/W2168931268","https://openalex.org/W2227591748","https://openalex.org/W2460950671","https://openalex.org/W2478384834","https://openalex.org/W2492634063","https://openalex.org/W2586732979","https://openalex.org/W2981325821"],"related_works":["https://openalex.org/W2001202614","https://openalex.org/W2801134548","https://openalex.org/W7221041807","https://openalex.org/W6986256239","https://openalex.org/W2052045096","https://openalex.org/W7067729447","https://openalex.org/W2000633119","https://openalex.org/W4233367621","https://openalex.org/W3025205663","https://openalex.org/W3024247226"],"abstract_inverted_index":{"Orientador":[0],":":[1],"Prof.":[2],"Dr.":[3],"Claudio":[4],"da":[5],"Cunha":[6]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2016-06-24T00:00:00"}