{"id":"https://openalex.org/W1522340786","doi":"https://doi.org/10.1186/1471-2091-4-18","title":"Riboflavin synthase of Schizosaccharomyces pombe. Protein dynamics revealed by 19F NMR protein perturbation experiments","display_name":"Riboflavin synthase of Schizosaccharomyces pombe. Protein dynamics revealed by 19F NMR protein perturbation experiments","publication_year":2003,"publication_date":"2003-12-23","ids":{"openalex":"https://openalex.org/W1522340786","doi":"https://doi.org/10.1186/1471-2091-4-18","mag":"1522340786","pmid":"https://pubmed.ncbi.nlm.nih.gov/14690539","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/337094"},"language":"en","primary_location":{"id":"doi:10.1186/1471-2091-4-18","doi":"https://doi.org/10.1186/1471-2091-4-18","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2091-4-18","pdf_url":"https://bmcbiochem.biomedcentral.com/counter/pdf/10.1186/1471-2091-4-18","source":{"id":"https://openalex.org/S120371716","display_name":"BMC Biochemistry","issn_l":"1471-2091","issn":["1471-2091"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","poland-70"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Biochemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://bmcbiochem.biomedcentral.com/counter/pdf/10.1186/1471-2091-4-18","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5006304159","display_name":"Markus J. Fischer","orcid":"https://orcid.org/0000-0001-7243-4199","observed_orcids":["https://orcid.org/0000-0001-7243-4199"]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":true,"raw_author_name":"Markus Fischer","raw_affiliation_strings":["Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Lichten-bergstr, 4, D-85747 Garching, Germany. markus.fischer@ch.tum.de","Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Garching, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Lichten-bergstr, 4, D-85747 Garching, Germany. markus.fischer@ch.tum.de","institution_ids":["https://openalex.org/I62916508"]},{"raw_affiliation_string":"Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Garching, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5031329412","display_name":"A.K. Schott","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Ann-Kathrin Schott","raw_affiliation_strings":["Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Lichten-bergstr. 4, D-85747, Garching, Germany","Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Garching, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Lichten-bergstr. 4, D-85747, Garching, Germany","institution_ids":["https://openalex.org/I62916508"]},{"raw_affiliation_string":"Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Garching, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016719018","display_name":"Kristina F. Kemter","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Kristina Kemter","raw_affiliation_strings":["Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Lichten-bergstr. 4, D-85747, Garching, Germany","Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Garching, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Lichten-bergstr. 4, D-85747, Garching, Germany","institution_ids":["https://openalex.org/I62916508"]},{"raw_affiliation_string":"Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Garching, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5067484887","display_name":"Richard Feicht","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Richard Feicht","raw_affiliation_strings":["Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Lichten-bergstr. 4, D-85747, Garching, Germany","Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Garching, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Lichten-bergstr. 4, D-85747, Garching, Germany","institution_ids":["https://openalex.org/I62916508"]},{"raw_affiliation_string":"Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Garching, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079134590","display_name":"Gerald Richter","orcid":"https://orcid.org/0000-0002-2870-1568","observed_orcids":["https://orcid.org/0000-0002-2870-1568"]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Gerald Richter","raw_affiliation_strings":["Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Lichten-bergstr. 4, D-85747, Garching, Germany","Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Garching, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Lichten-bergstr. 4, D-85747, Garching, Germany","institution_ids":["https://openalex.org/I62916508"]},{"raw_affiliation_string":"Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Garching, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5060786264","display_name":"Boris A. Illarionov","orcid":"https://orcid.org/0009-0007-8489-0651","observed_orcids":["https://orcid.org/0009-0007-8489-0651"]},"institutions":[{"id":"https://openalex.org/I4210110184","display_name":"Institute of Biophysics","ror":"https://ror.org/01mq8sh52","country_code":"RU","type":"facility","lineage":["https://openalex.org/I1313323035","https://openalex.org/I4210110184","https://openalex.org/I4210129690"]}],"countries":["RU"],"is_corresponding":false,"raw_author_name":"Boris Illarionov","raw_affiliation_strings":["The Institute for Biophysics, Krasnoyarsk, Russia"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Institute for Biophysics, Krasnoyarsk, Russia","institution_ids":["https://openalex.org/I4210110184"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086504004","display_name":"Wolfgang Eisenreich","orcid":"https://orcid.org/0000-0002-9832-8279","observed_orcids":["https://orcid.org/0000-0002-9832-8279"]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Wolfgang Eisenreich","raw_affiliation_strings":["Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Lichten-bergstr. 4, D-85747, Garching, Germany","Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Garching, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Lichten-bergstr. 4, D-85747, Garching, Germany","institution_ids":["https://openalex.org/I62916508"]},{"raw_affiliation_string":"Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Garching, Germany","institution_ids":["https://openalex.org/I62916508"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013571136","display_name":"S. Gerhardt","orcid":"https://orcid.org/0000-0002-9098-8475","observed_orcids":["https://orcid.org/0000-0002-9098-8475"]},"institutions":[{"id":"https://openalex.org/I4210150093","display_name":"Max Planck Institute of Biochemistry","ror":"https://ror.org/04py35477","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210150093"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Stefan Gerhardt","raw_affiliation_strings":["Department of Protein Crystallography, Max-Planck-Institut f\u00fcr Biochemie, Am Klopferspitz 18a, D-82512, Martinsried, Germany","Department of Protein Crystallography, Max-Planck-Institut f\u00fcr Biochemie, Martinsried, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Protein Crystallography, Max-Planck-Institut f\u00fcr Biochemie, Am Klopferspitz 18a, D-82512, Martinsried, Germany","institution_ids":["https://openalex.org/I4210150093"]},{"raw_affiliation_string":"Department of Protein Crystallography, Max-Planck-Institut f\u00fcr Biochemie, Martinsried, Germany","institution_ids":["https://openalex.org/I4210150093"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5107458395","display_name":"Mark Cushman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I219193219","display_name":"Purdue University West Lafayette","ror":"https://ror.org/02dqehb95","country_code":"US","type":"education","lineage":["https://openalex.org/I219193219"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mark Cushman","raw_affiliation_strings":["Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana, USA","Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, Indiana, USA","institution_ids":["https://openalex.org/I219193219"]},{"raw_affiliation_string":"Department of Medicinal Chemistry and Molecular Pharmacology, Purdue University, West Lafayette, USA","institution_ids":["https://openalex.org/I219193219"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5050783675","display_name":"Stefan Steinbacher","orcid":"https://orcid.org/0000-0002-4224-8317","observed_orcids":["https://orcid.org/0000-0002-4224-8317"]},"institutions":[{"id":"https://openalex.org/I4210150093","display_name":"Max Planck Institute of Biochemistry","ror":"https://ror.org/04py35477","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210150093"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Stefan Steinbacher","raw_affiliation_strings":["Department of Protein Crystallography, Max-Planck-Institut f\u00fcr Biochemie, Am Klopferspitz 18a, D-82512, Martinsried, Germany","Department of Protein Crystallography, Max-Planck-Institut f\u00fcr Biochemie, Martinsried, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Protein Crystallography, Max-Planck-Institut f\u00fcr Biochemie, Am Klopferspitz 18a, D-82512, Martinsried, Germany","institution_ids":["https://openalex.org/I4210150093"]},{"raw_affiliation_string":"Department of Protein Crystallography, Max-Planck-Institut f\u00fcr Biochemie, Martinsried, Germany","institution_ids":["https://openalex.org/I4210150093"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101832860","display_name":"Robert Huber","orcid":"https://orcid.org/0000-0002-0133-5334","observed_orcids":["https://orcid.org/0000-0002-0133-5334"]},"institutions":[{"id":"https://openalex.org/I4210150093","display_name":"Max Planck Institute of Biochemistry","ror":"https://ror.org/04py35477","country_code":"DE","type":"facility","lineage":["https://openalex.org/I149899117","https://openalex.org/I4210150093"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Robert Huber","raw_affiliation_strings":["Department of Protein Crystallography, Max-Planck-Institut f\u00fcr Biochemie, Am Klopferspitz 18a, D-82512, Martinsried, Germany","Department of Protein Crystallography, Max-Planck-Institut f\u00fcr Biochemie, Martinsried, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Protein Crystallography, Max-Planck-Institut f\u00fcr Biochemie, Am Klopferspitz 18a, D-82512, Martinsried, Germany","institution_ids":["https://openalex.org/I4210150093"]},{"raw_affiliation_string":"Department of Protein Crystallography, Max-Planck-Institut f\u00fcr Biochemie, Martinsried, Germany","institution_ids":["https://openalex.org/I4210150093"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5068798153","display_name":"Adelbert Bacher","orcid":"https://orcid.org/0000-0001-5174-4139","observed_orcids":["https://orcid.org/0000-0001-5174-4139"]},"institutions":[{"id":"https://openalex.org/I62916508","display_name":"Technical University of Munich","ror":"https://ror.org/02kkvpp62","country_code":"DE","type":"education","lineage":["https://openalex.org/I62916508"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Adelbert Bacher","raw_affiliation_strings":["Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Lichten-bergstr. 4, D-85747, Garching, Germany","Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Garching, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Lichten-bergstr. 4, D-85747, Garching, Germany","institution_ids":["https://openalex.org/I62916508"]},{"raw_affiliation_string":"Lehrstuhl f\u00fcr Organische Chemie und Biochemie, Technische Universit\u00e4t M\u00fcnchen, Garching, Germany","institution_ids":["https://openalex.org/I62916508"]}]}],"institutions":[],"countries_distinct_count":3,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5006304159"],"corresponding_institution_ids":["https://openalex.org/I62916508"],"apc_list":{"value":2170,"currency":"USD","value_usd":2170},"apc_paid":null,"fwci":0.3772,"has_fulltext":true,"cited_by_count":19,"citation_normalized_percentile":{"value":0.49257248,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"4","issue":"1","first_page":"18","last_page":"18"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12827","display_name":"Biochemical and Molecular Research","score":0.5889000296592712,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12827","display_name":"Biochemical and Molecular Research","score":0.5889000296592712,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.1851000040769577,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11809","display_name":"Advanced NMR Techniques and Applications","score":0.11940000206232071,"subfield":{"id":"https://openalex.org/subfields/1607","display_name":"Spectroscopy"},"field":{"id":"https://openalex.org/fields/16","display_name":"Chemistry"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/riboflavin-synthase","display_name":"riboflavin synthase","score":1.0},{"id":"https://openalex.org/keywords/schizosaccharomyces-pombe","display_name":"Schizosaccharomyces pombe","score":0.996999979019165},{"id":"https://openalex.org/keywords/riboflavin-biosynthesis","display_name":"riboflavin biosynthesis","score":0.9229999780654907},{"id":"https://openalex.org/keywords/6-7-dimethyl-8-ribityllumazine","display_name":"6,7-dimethyl-8-ribityllumazine","score":0.9789999723434448},{"id":"https://openalex.org/keywords/protein-dynamics","display_name":"protein dynamics","score":0.5960000157356262},{"id":"https://openalex.org/keywords/enzyme-mechanism","display_name":"enzyme mechanism","score":0.4099999964237213},{"id":"https://openalex.org/keywords/disproportionation","display_name":"disproportionation","score":0.6710000038146973},{"id":"https://openalex.org/keywords/homotrimer","display_name":"homotrimer","score":0.609000027179718},{"id":"https://openalex.org/keywords/anti-infective-drug-targets","display_name":"anti-infective drug targets","score":0.7089999914169312}],"concepts":[{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6573753952980042},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.6155833005905151},{"id":"https://openalex.org/C112243037","wikidata":"https://www.wikidata.org/wiki/Q22327117","display_name":"ATP synthase","level":3,"score":0.5882288813591003},{"id":"https://openalex.org/C2779429346","wikidata":"https://www.wikidata.org/wiki/Q2236682","display_name":"Schizosaccharomyces pombe","level":4,"score":0.5587848424911499},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.44690343737602234},{"id":"https://openalex.org/C71240020","wikidata":"https://www.wikidata.org/wiki/Q186011","display_name":"Stereochemistry","level":1,"score":0.43758338689804077},{"id":"https://openalex.org/C2779222958","wikidata":"https://www.wikidata.org/wiki/Q45422","display_name":"Yeast","level":2,"score":0.35186222195625305},{"id":"https://openalex.org/C2777576037","wikidata":"https://www.wikidata.org/wiki/Q719725","display_name":"Saccharomyces cerevisiae","level":3,"score":0.21835768222808838}],"mesh":[{"descriptor_ui":"D000595","descriptor_name":"Amino Acid Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005461","descriptor_name":"Fluorine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008969","descriptor_name":"Molecular Sequence Data","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011621","descriptor_name":"Pteridines","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012256","descriptor_name":"Riboflavin","qualifier_ui":"Q000096","qualifier_name":"biosynthesis","is_major_topic":false},{"descriptor_ui":"D012258","descriptor_name":"Riboflavin Synthase","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D012258","descriptor_name":"Riboflavin Synthase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D012258","descriptor_name":"Riboflavin Synthase","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D012568","descriptor_name":"Schizosaccharomyces","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D017386","descriptor_name":"Sequence Homology, Amino Acid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019906","descriptor_name":"Nuclear Magnetic Resonance, Biomolecular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":9,"locations":[{"id":"doi:10.1186/1471-2091-4-18","doi":"https://doi.org/10.1186/1471-2091-4-18","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2091-4-18","pdf_url":"https://bmcbiochem.biomedcentral.com/counter/pdf/10.1186/1471-2091-4-18","source":{"id":"https://openalex.org/S120371716","display_name":"BMC Biochemistry","issn_l":"1471-2091","issn":["1471-2091"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","poland-70"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Biochemistry","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:337094","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/337094","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Biochem","raw_type":"Text"},{"id":"pmid:14690539","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/14690539","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC biochemistry","raw_type":"Journal Article"},{"id":"pmh:oai:docs.lib.purdue.edu:mcmppubs-1003","doi":null,"is_oa":true,"landing_page_url":"https://docs.lib.purdue.edu/mcmppubs/4","pdf_url":"https://docs.lib.purdue.edu/cgi/viewcontent.cgi?article=1003&context=mcmppubs","source":{"id":"https://openalex.org/S4377196310","display_name":"Purdue e-Pubs (Purdue University System)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2801333002","host_organization_name":"Purdue University System","host_organization_lineage":["https://openalex.org/I2801333002"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Borch Department of Medicinal Chemistry and Molecular Pharmacology Faculty Publications","raw_type":"text"},{"id":"pmh:oai:pure.mpg.de:item_1581882","doi":null,"is_oa":true,"landing_page_url":"https://hdl.handle.net/11858/00-001M-0000-0010-6D6F-F","pdf_url":"https://hdl.handle.net/11858/00-001M-0000-0010-6D6E-2","source":{"id":"https://openalex.org/S4306400654","display_name":"MPG.PuRe (Max Planck Society)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I149899117","host_organization_name":"Max Planck Society","host_organization_lineage":["https://openalex.org/I149899117"],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Biochemistry","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.1021.1344","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.1021.1344","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://pubman.mpdl.mpg.de/pubman/item/escidoc%3A1581882/component/escidoc%3A1581881/1471-2091-4-18%5B1%5D.pdf","raw_type":"text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.284.7740","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.284.7740","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"ftp://ftp.ncbi.nlm.nih.gov/pub/pmc/46/1f/BMC_Biochem_2003_Dec_23_4_18.tar.gz","raw_type":"text"},{"id":"pmh:oai:doaj.org/article:b3874bbe5e434ac8b08176185af66169","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/b3874bbe5e434ac8b08176185af66169","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Biochemistry, Vol 4, Iss 1, p 18 (2003)","raw_type":"article"},{"id":"pmh:oai:edoc.mpg.de:174616","doi":null,"is_oa":false,"landing_page_url":"http://edoc.mpg.de/174616","pdf_url":null,"source":{"id":"https://openalex.org/S4406922265","display_name":"Max Planck Institute for Plasma Physics","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Biochemistry, v.4, [1]-[19] (2003)","raw_type":"Article"}],"best_oa_location":{"id":"doi:10.1186/1471-2091-4-18","doi":"https://doi.org/10.1186/1471-2091-4-18","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-2091-4-18","pdf_url":"https://bmcbiochem.biomedcentral.com/counter/pdf/10.1186/1471-2091-4-18","source":{"id":"https://openalex.org/S120371716","display_name":"BMC Biochemistry","issn_l":"1471-2091","issn":["1471-2091"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","poland-70"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Biochemistry","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4233561887","display_name":"Ligands for Probing the Active Site of Lumazine Synthase","funder_award_id":"R01GM051469","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"}],"funders":[{"id":"https://openalex.org/F4320320879","display_name":"Deutsche Forschungsgemeinschaft","ror":"https://ror.org/018mejw64"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1522340786.pdf","grobid_xml":"https://content.openalex.org/works/W1522340786.grobid-xml"},"referenced_works_count":50,"referenced_works":["https://openalex.org/W180603313","https://openalex.org/W188468884","https://openalex.org/W597159688","https://openalex.org/W1039779313","https://openalex.org/W1481378379","https://openalex.org/W1481985525","https://openalex.org/W1487867154","https://openalex.org/W1514136353","https://openalex.org/W1547638309","https://openalex.org/W1559761893","https://openalex.org/W1698351509","https://openalex.org/W1967517192","https://openalex.org/W1981776711","https://openalex.org/W1991060128","https://openalex.org/W1991659634","https://openalex.org/W1997180556","https://openalex.org/W1997967581","https://openalex.org/W2002826175","https://openalex.org/W2014437352","https://openalex.org/W2015188850","https://openalex.org/W2018289835","https://openalex.org/W2025012320","https://openalex.org/W2028392335","https://openalex.org/W2034861264","https://openalex.org/W2057741724","https://openalex.org/W2066157388","https://openalex.org/W2067133614","https://openalex.org/W2072555826","https://openalex.org/W2080765791","https://openalex.org/W2082249244","https://openalex.org/W2088144279","https://openalex.org/W2088555826","https://openalex.org/W2094095270","https://openalex.org/W2100837269","https://openalex.org/W2126865613","https://openalex.org/W2138270253","https://openalex.org/W2164045961","https://openalex.org/W2166071706","https://openalex.org/W2253374603","https://openalex.org/W2307635858","https://openalex.org/W2329886072","https://openalex.org/W2338653879","https://openalex.org/W2414489610","https://openalex.org/W2414805111","https://openalex.org/W2466841613","https://openalex.org/W2616645268","https://openalex.org/W2951888752","https://openalex.org/W4229536270","https://openalex.org/W4285719527","https://openalex.org/W4323285025"],"related_works":["https://openalex.org/W7140245440","https://openalex.org/W7095361453","https://openalex.org/W2996100991","https://openalex.org/W7100552931","https://openalex.org/W2616645268","https://openalex.org/W7140243411","https://openalex.org/W1991659634","https://openalex.org/W2158660006","https://openalex.org/W1967517192","https://openalex.org/W7140246978"],"abstract_inverted_index":null,"counts_by_year":[{"year":2023,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}
