{"id":"https://openalex.org/W1520719263","doi":"https://doi.org/10.1111/j.1439-0418.2010.01528.x","title":"Cytotoxic effects of parasitism and application of venom from the endoparasitoid Pimpla turionellae on hemocytes of the host Galleria mellonella","display_name":"Cytotoxic effects of parasitism and application of venom from the endoparasitoid Pimpla turionellae on hemocytes of the host Galleria mellonella","publication_year":2010,"publication_date":"2010-05-21","ids":{"openalex":"https://openalex.org/W1520719263","doi":"https://doi.org/10.1111/j.1439-0418.2010.01528.x","mag":"1520719263"},"language":"en","primary_location":{"id":"doi:10.1111/j.1439-0418.2010.01528.x","doi":"https://doi.org/10.1111/j.1439-0418.2010.01528.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1439-0418.2010.01528.x","pdf_url":null,"source":{"id":"https://openalex.org/S87930725","display_name":"Journal of Applied Entomology","issn_l":"0931-2048","issn":["0931-2048","1439-0418"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Applied Entomology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5013111211","display_name":"Aylin Er","orcid":"https://orcid.org/0000-0002-8108-8950","observed_orcids":["https://orcid.org/0000-0002-8108-8950"]},"institutions":[{"id":"https://openalex.org/I115600380","display_name":"Bal\u0131kesir University","ror":"https://ror.org/02tv7db43","country_code":"TR","type":"education","lineage":["https://openalex.org/I115600380"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"A. Er","raw_affiliation_strings":["Faculty of Science-Literature, Department of Biology, Bal\u0131kesir University, Bal\u0131kesir, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Science-Literature, Department of Biology, Bal\u0131kesir University, Bal\u0131kesir, Turkey","institution_ids":["https://openalex.org/I115600380"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5070811995","display_name":"Fevzi U\u00e7kan","orcid":"https://orcid.org/0000-0001-9304-4296","observed_orcids":["https://orcid.org/0000-0001-9304-4296"]},"institutions":[{"id":"https://openalex.org/I51826884","display_name":"Kocaeli \u00dcniversitesi","ror":"https://ror.org/0411seq30","country_code":"TR","type":"education","lineage":["https://openalex.org/I51826884"]}],"countries":["TR"],"is_corresponding":true,"raw_author_name":"F. U\u00e7kan","raw_affiliation_strings":["Faculty of Science-Literature, Department of Biology, Kocaeli University, I\u0307zmit, Kocaeli, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Science-Literature, Department of Biology, Kocaeli University, I\u0307zmit, Kocaeli, Turkey","institution_ids":["https://openalex.org/I51826884"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057783899","display_name":"David Rivers","orcid":"https://orcid.org/0000-0002-6794-7851","observed_orcids":["https://orcid.org/0000-0002-6794-7851"]},"institutions":[{"id":"https://openalex.org/I165556055","display_name":"Loyola University Maryland","ror":"https://ror.org/01by1wp65","country_code":"US","type":"education","lineage":["https://openalex.org/I165556055"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"D. B. Rivers","raw_affiliation_strings":["Department of Biology, Loyola University Maryland, Baltimore, MD, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biology, Loyola University Maryland, Baltimore, MD, USA","institution_ids":["https://openalex.org/I165556055"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5041140983","display_name":"Olga Sak","orcid":"https://orcid.org/0000-0003-4815-7798","observed_orcids":["https://orcid.org/0000-0003-4815-7798"]},"institutions":[{"id":"https://openalex.org/I115600380","display_name":"Bal\u0131kesir University","ror":"https://ror.org/02tv7db43","country_code":"TR","type":"education","lineage":["https://openalex.org/I115600380"]}],"countries":["TR"],"is_corresponding":false,"raw_author_name":"O. Sak","raw_affiliation_strings":["Faculty of Science-Literature, Department of Biology, Bal\u0131kesir University, Bal\u0131kesir, Turkey"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Faculty of Science-Literature, Department of Biology, Bal\u0131kesir University, Bal\u0131kesir, Turkey","institution_ids":["https://openalex.org/I115600380"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":["https://openalex.org/A5013111211","https://openalex.org/A5070811995"],"corresponding_institution_ids":["https://openalex.org/I115600380","https://openalex.org/I51826884"],"apc_list":{"value":4780,"currency":"USD","value_usd":4780},"apc_paid":null,"fwci":0.8996,"has_fulltext":false,"cited_by_count":33,"citation_normalized_percentile":{"value":0.70495113,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"135","issue":"3","first_page":"225","last_page":"236"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11403","display_name":"Invertebrate Immune Response Mechanisms","score":0.9038000106811523,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11403","display_name":"Invertebrate Immune Response Mechanisms","score":0.9038000106811523,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12132","display_name":"Hymenoptera taxonomy and phylogeny","score":0.043299999088048935,"subfield":{"id":"https://openalex.org/subfields/1105","display_name":"Ecology, Evolution, Behavior and Systematics"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11353","display_name":"Venomous Animal Envenomation and Studies","score":0.013799999840557575,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pimpla-turionellae","display_name":"Pimpla turionellae","score":1.0},{"id":"https://openalex.org/keywords/galleria-mellonella","display_name":"Galleria mellonella","score":0.9629999995231628},{"id":"https://openalex.org/keywords/parasitoid-venom","display_name":"parasitoid venom","score":0.953000009059906},{"id":"https://openalex.org/keywords/endoparasitoid","display_name":"endoparasitoid","score":0.7689999938011169},{"id":"https://openalex.org/keywords/hemocytes","display_name":"hemocytes","score":0.7730000019073486},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.7789999842643738},{"id":"https://openalex.org/keywords/necrosis","display_name":"necrosis","score":0.984000027179718},{"id":"https://openalex.org/keywords/hemocyte-viability","display_name":"hemocyte viability","score":0.7710000276565552},{"id":"https://openalex.org/keywords/mitotic-index","display_name":"mitotic index","score":0.9549999833106995},{"id":"https://openalex.org/keywords/host-developmental-stage","display_name":"host developmental stage","score":0.6790000200271606},{"id":"https://openalex.org/keywords/pupae","display_name":"pupae","score":0.4059999883174896},{"id":"https://openalex.org/keywords/larvae","display_name":"larva","score":0.9629999995231628},{"id":"https://openalex.org/keywords/annexin-v-fitc","display_name":"annexin V-FITC","score":0.7170000076293945},{"id":"https://openalex.org/keywords/propidium-iodide","display_name":"propidium iodide","score":0.9229999780654907},{"id":"https://openalex.org/keywords/plasma-membrane-integrity","display_name":"plasma membrane integrity","score":0.6259999871253967}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8909401893615723},{"id":"https://openalex.org/C2779032433","wikidata":"https://www.wikidata.org/wiki/Q761648","display_name":"Galleria mellonella","level":4,"score":0.844174861907959},{"id":"https://openalex.org/C100068826","wikidata":"https://www.wikidata.org/wiki/Q485675","display_name":"Hemolymph","level":2,"score":0.7687937021255493},{"id":"https://openalex.org/C2779448229","wikidata":"https://www.wikidata.org/wiki/Q3386847","display_name":"Venom","level":2,"score":0.7085844874382019},{"id":"https://openalex.org/C2778234367","wikidata":"https://www.wikidata.org/wiki/Q186517","display_name":"Parasitism","level":3,"score":0.56505286693573},{"id":"https://openalex.org/C2779873666","wikidata":"https://www.wikidata.org/wiki/Q1138186","display_name":"Ichneumonidae","level":4,"score":0.5262545347213745},{"id":"https://openalex.org/C145600735","wikidata":"https://www.wikidata.org/wiki/Q3055418","display_name":"Envenomation","level":3,"score":0.523235023021698},{"id":"https://openalex.org/C2778260489","wikidata":"https://www.wikidata.org/wiki/Q595663","display_name":"Parasitoid","level":3,"score":0.522247850894928},{"id":"https://openalex.org/C2776776645","wikidata":"https://www.wikidata.org/wiki/Q248425","display_name":"Pyralidae","level":3,"score":0.5178406834602356},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.41361016035079956},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.36127960681915283},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.3478263020515442},{"id":"https://openalex.org/C177756618","wikidata":"https://www.wikidata.org/wiki/Q6527674","display_name":"Lepidoptera genitalia","level":2,"score":0.33814990520477295},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.3258001506328583},{"id":"https://openalex.org/C173758957","wikidata":"https://www.wikidata.org/wiki/Q129270","display_name":"Larva","level":2,"score":0.2844729423522949},{"id":"https://openalex.org/C126831891","wikidata":"https://www.wikidata.org/wiki/Q221673","display_name":"Host (biology)","level":2,"score":0.16573309898376465},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.12091830372810364},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.10458728671073914},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.0},{"id":"https://openalex.org/C60987743","wikidata":"https://www.wikidata.org/wiki/Q1460232","display_name":"Virulence","level":3,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1439-0418.2010.01528.x","doi":"https://doi.org/10.1111/j.1439-0418.2010.01528.x","is_oa":false,"landing_page_url":"https://doi.org/10.1111/j.1439-0418.2010.01528.x","pdf_url":null,"source":{"id":"https://openalex.org/S87930725","display_name":"Journal of Applied Entomology","issn_l":"0931-2048","issn":["0931-2048","1439-0418"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-c","jufo-1","norway-1","poland-100","russia-white-list-1"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Applied Entomology","raw_type":"journal-article"},{"id":"pmh:3c5d3631-cff9-422a-af05-3d60da99e2cd","doi":null,"is_oa":false,"landing_page_url":"https://avesis.kocaeli.edu.tr/publication/details/3c5d3631-cff9-422a-af05-3d60da99e2cd/oai","pdf_url":null,"source":{"id":"https://openalex.org/S7407055291","display_name":"Kocaeli \u00dcniversitesi - AVES\u0130S","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4043000042438507,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":37,"referenced_works":["https://openalex.org/W153843189","https://openalex.org/W649559389","https://openalex.org/W1588097017","https://openalex.org/W1589917428","https://openalex.org/W1884992087","https://openalex.org/W1965039904","https://openalex.org/W1968507917","https://openalex.org/W1977026617","https://openalex.org/W1982156166","https://openalex.org/W1990525374","https://openalex.org/W1993362382","https://openalex.org/W2007023648","https://openalex.org/W2007238190","https://openalex.org/W2010959781","https://openalex.org/W2022731496","https://openalex.org/W2024954759","https://openalex.org/W2025313908","https://openalex.org/W2026647769","https://openalex.org/W2041492367","https://openalex.org/W2047803867","https://openalex.org/W2047955907","https://openalex.org/W2050962597","https://openalex.org/W2057121501","https://openalex.org/W2058521588","https://openalex.org/W2078457814","https://openalex.org/W2078813621","https://openalex.org/W2078925536","https://openalex.org/W2083852098","https://openalex.org/W2088859334","https://openalex.org/W2089517023","https://openalex.org/W2090609649","https://openalex.org/W2102059944","https://openalex.org/W2110967615","https://openalex.org/W2149860086","https://openalex.org/W2170625553","https://openalex.org/W2221497935","https://openalex.org/W4239073591"],"related_works":["https://openalex.org/W2109227338","https://openalex.org/W1495579849","https://openalex.org/W2564851095","https://openalex.org/W2120858444","https://openalex.org/W3137448528","https://openalex.org/W2078813621","https://openalex.org/W7131944715","https://openalex.org/W1969314921","https://openalex.org/W153718041","https://openalex.org/W2187780830"],"abstract_inverted_index":{"In":[0,161],"parasitoid":[1],"species":[2],"devoid":[3],"of":[4,18,39,73,100,114,128,147,207,222,225,238,257,261,265,276,289],"polydnaviruses":[5],"and":[6,48,53,75,80,90,97,130,139,143,154,177,196,201,214,218],"virus-like":[7],"particles,":[8],"venom":[9,148,239],"appears":[10],"to":[11,35,61,151,247],"play":[12],"a":[13,37,274],"major":[14],"role":[15],"in":[16,83,107,118,135,165,171,182,212,292],"suppression":[17],"host":[19,123],"immunity.":[20],"Venom":[21],"from":[22],"the":[23,71,112,122,235,255,281],"pupal":[24],"endoparasitoid":[25],"Pimpla":[26],"turionellae":[27,69,105],"L.":[28,86],"(Hymenoptera:":[29],"Ichneumonidae)":[30],"has":[31],"previously":[32],"been":[33],"shown":[34],"contain":[36],"mixture":[38],"biologically":[40],"active":[41],"components,":[42],"which":[43],"display":[44],"potent":[45],"paralytic,":[46],"cytotoxic,":[47],"cytolytic":[49],"effects":[50,110],"toward":[51],"lepidopteran":[52],"dipteran":[54],"hosts.":[55],"The":[56,126,184,205],"current":[57],"study":[58,93],"was":[59,168,180],"undertaken":[60],"investigate":[62],"if":[63],"parasitism":[64,96],"and/or":[65],"envenomation":[66,99],"by":[67,103,287],"P.":[68,104],"affects":[70],"frequency":[72],"apoptotic":[74,115,132],"necrotic":[76,166],"hemocytes,":[77],"hemocyte":[78,186],"viability":[79,187],"mitotic":[81,208],"indices":[82],"Galleria":[84],"mellonella":[85,102,137],"(Lepidoptera:":[87],"Pyralidae)":[88],"pupae":[89,138,173,192,213],"larvae.":[91,183],"Our":[92],"indicates":[94],"that":[95],"experimental":[98],"G.":[101,136],"resulted":[106],"markedly":[108],"different":[109],"on":[111,121],"ratio":[113,127,206],"hemocytes":[116,133,167,209,226,258,271],"circulating":[117],"hemolymph":[119],"depending":[120],"developmental":[124],"stages.":[125],"early":[129,266],"late":[131],"increased":[134],"larvae":[140,215],"upon":[141,216],"parasitization":[142,217],"at":[144,174,198,219,280],"high":[145,220],"doses":[146,221],"when":[149],"compared":[150],"untreated,":[152],"null":[153],"Phosphate":[155],"Buffered":[156],"Saline":[157],"(PBS)":[158],"injected":[159],"controls.":[160],"contrast,":[162],"an":[163],"increase":[164],"only":[169],"observed":[170,181,190],"parasitized":[172],"24":[175,202],"h":[176,203,251],"no":[178],"difference":[179],"lowest":[185],"values":[188],"were":[189],"with":[191,227],"as":[193,285],"69.87%,":[194],"69.80%,":[195],"72.47%":[197],"4,":[199],"8,":[200],"post-parasitism.":[204],"also":[210,272],"decreased":[211],"venom.":[223,248],"Staining":[224],"annexin":[228],"V-FITC":[229],"revealed":[230],"green":[231],"fluorescent":[232],"\u2018halos\u2019":[233],"along":[234],"plasma":[236,277],"membranes":[237],"treated":[240],"cells":[241],"within":[242],"15":[243],"min":[244],"following":[245],"exposure":[246],"By":[249],"1":[250],"post-venom":[252],"\u2013":[253],"treatment,":[254],"majority":[256],"displayed":[259,273],"binding":[260],"this":[262],"probe,":[263],"indicative":[264],"stage":[267],"apoptosis.":[268],"These":[269],"same":[270,282],"loss":[275],"membrane":[278],"integrity":[279],"time":[283],"points":[284],"evidenced":[286],"accumulation":[288],"propidium":[290],"iodide":[291],"nuclei.":[293]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":3},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}