{"id":"https://openalex.org/W1520080083","doi":"https://doi.org/10.1109/isbi.2015.7164152","title":"Probabilistic edge detection in 3D optical microscopy images of tissue samples","display_name":"Probabilistic edge detection in 3D optical microscopy images of tissue samples","publication_year":2015,"publication_date":"2015-04-01","ids":{"openalex":"https://openalex.org/W1520080083","doi":"https://doi.org/10.1109/isbi.2015.7164152","mag":"1520080083"},"language":"en","primary_location":{"id":"doi:10.1109/isbi.2015.7164152","doi":"https://doi.org/10.1109/isbi.2015.7164152","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2015.7164152","pdf_url":null,"source":{"id":"https://openalex.org/S4363605129","display_name":"IEEE International Symposium on Biomedical Imaging (ISBI)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 IEEE 12th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"},"volume":null,"type":"conference-paper","is_traditional":true,"indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5005148369","display_name":"Kaustav Nandy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4396570585","display_name":"Leidos Biomedical Research Inc. (United States)","ror":"https://ror.org/00bardy64","country_code":"US","type":"company","lineage":["https://openalex.org/I114662689","https://openalex.org/I4396570585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Kaustav Nandy","raw_affiliation_strings":["Optical Microscopy and Analysis Lab, Frederick National Laboratory for Cancer Research, Frederick, MD","Optical Microscopy and Analysis Lab, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick MD 21702"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Optical Microscopy and Analysis Lab, Frederick National Laboratory for Cancer Research, Frederick, MD","institution_ids":["https://openalex.org/I4210130649"]},{"raw_affiliation_string":"Optical Microscopy and Analysis Lab, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick MD 21702","institution_ids":["https://openalex.org/I4210130649","https://openalex.org/I4396570585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5017820293","display_name":"Prabhkar R. Gudla","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4396570585","display_name":"Leidos Biomedical Research Inc. (United States)","ror":"https://ror.org/00bardy64","country_code":"US","type":"company","lineage":["https://openalex.org/I114662689","https://openalex.org/I4396570585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Prabhkar R. Gudla","raw_affiliation_strings":["Optical Microscopy and Analysis Lab, Frederick National Laboratory for Cancer Research, Frederick, MD","Optical Microscopy and Analysis Lab, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick MD 21702"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Optical Microscopy and Analysis Lab, Frederick National Laboratory for Cancer Research, Frederick, MD","institution_ids":["https://openalex.org/I4210130649"]},{"raw_affiliation_string":"Optical Microscopy and Analysis Lab, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick MD 21702","institution_ids":["https://openalex.org/I4210130649","https://openalex.org/I4396570585"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102762707","display_name":"Rama Chellappa","orcid":"https://orcid.org/0000-0002-7638-1650","observed_orcids":["https://orcid.org/0000-0002-7638-1650"]},"institutions":[{"id":"https://openalex.org/I66946132","display_name":"University of Maryland, College Park","ror":"https://ror.org/047s2c258","country_code":"US","type":"education","lineage":["https://openalex.org/I66946132"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rama Chellappa","raw_affiliation_strings":["Department of Electrical and Computer Engineering, University of Maryland, MD","Department of Electrical and Computer Engineering University of Maryland College Park, MD 20742"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Electrical and Computer Engineering, University of Maryland, MD","institution_ids":["https://openalex.org/I66946132"]},{"raw_affiliation_string":"Department of Electrical and Computer Engineering University of Maryland College Park, MD 20742","institution_ids":["https://openalex.org/I66946132"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5013163732","display_name":"Stephen Lockett","orcid":"https://orcid.org/0000-0002-2010-9914","observed_orcids":["https://orcid.org/0000-0002-2010-9914"]},"institutions":[{"id":"https://openalex.org/I4210130649","display_name":"Frederick National Laboratory for Cancer Research","ror":"https://ror.org/03v6m3209","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238","https://openalex.org/I4210130649","https://openalex.org/I4210140884"]},{"id":"https://openalex.org/I4396570585","display_name":"Leidos Biomedical Research Inc. (United States)","ror":"https://ror.org/00bardy64","country_code":"US","type":"company","lineage":["https://openalex.org/I114662689","https://openalex.org/I4396570585"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stephen J. Lockett","raw_affiliation_strings":["Optical Microscopy and Analysis Lab, Frederick National Laboratory for Cancer Research, Frederick, MD","Optical Microscopy and Analysis Lab, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick MD 21702"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Optical Microscopy and Analysis Lab, Frederick National Laboratory for Cancer Research, Frederick, MD","institution_ids":["https://openalex.org/I4210130649"]},{"raw_affiliation_string":"Optical Microscopy and Analysis Lab, Leidos Biomedical Research, Inc., Frederick National Laboratory for Cancer Research, Frederick MD 21702","institution_ids":["https://openalex.org/I4210130649","https://openalex.org/I4396570585"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.02942409,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"1462","last_page":"1465"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12549","display_name":"Image and Object Detection Techniques","score":0.7592999935150146,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T12549","display_name":"Image and Object Detection Techniques","score":0.7592999935150146,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T12859","display_name":"Cell Image Analysis Techniques","score":0.11829999834299088,"subfield":{"id":"https://openalex.org/subfields/1304","display_name":"Biophysics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10052","display_name":"Medical Image Segmentation Techniques","score":0.04580000042915344,"subfield":{"id":"https://openalex.org/subfields/1707","display_name":"Computer Vision and Pattern Recognition"},"field":{"id":"https://openalex.org/fields/17","display_name":"Computer Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/3d-edge-detection","display_name":"3D edge detection","score":0.9409999847412109},{"id":"https://openalex.org/keywords/fluorescence-microscopy","display_name":"fluorescence microscopy","score":0.7549999952316284},{"id":"https://openalex.org/keywords/tissue-samples","display_name":"tissue samples","score":0.7850000262260437},{"id":"https://openalex.org/keywords/multiscale-analysis","display_name":"multiscale analysis","score":0.6779999732971191},{"id":"https://openalex.org/keywords/textural-properties","display_name":"textural properties","score":0.6959999799728394},{"id":"https://openalex.org/keywords/spectral-properties","display_name":"spectral properties","score":0.7889999747276306},{"id":"https://openalex.org/keywords/edge-maps","display_name":"edge maps","score":0.6359999775886536}],"concepts":[{"id":"https://openalex.org/C193536780","wikidata":"https://www.wikidata.org/wiki/Q1513153","display_name":"Edge detection","level":4,"score":0.690133810043335},{"id":"https://openalex.org/C49937458","wikidata":"https://www.wikidata.org/wiki/Q2599292","display_name":"Probabilistic logic","level":2,"score":0.6767171025276184},{"id":"https://openalex.org/C125245961","wikidata":"https://www.wikidata.org/wiki/Q221656","display_name":"Brightness","level":2,"score":0.6682443618774414},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.659166693687439},{"id":"https://openalex.org/C31972630","wikidata":"https://www.wikidata.org/wiki/Q844240","display_name":"Computer vision","level":1,"score":0.649564266204834},{"id":"https://openalex.org/C162307627","wikidata":"https://www.wikidata.org/wiki/Q204833","display_name":"Enhanced Data Rates for GSM Evolution","level":2,"score":0.6396533846855164},{"id":"https://openalex.org/C147080431","wikidata":"https://www.wikidata.org/wiki/Q1074953","display_name":"Microscopy","level":2,"score":0.6043174862861633},{"id":"https://openalex.org/C16345878","wikidata":"https://www.wikidata.org/wiki/Q107472979","display_name":"Orientation (vector space)","level":2,"score":0.5842804312705994},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.574796199798584},{"id":"https://openalex.org/C94915269","wikidata":"https://www.wikidata.org/wiki/Q1834857","display_name":"Detector","level":2,"score":0.5522841215133667},{"id":"https://openalex.org/C14705441","wikidata":"https://www.wikidata.org/wiki/Q597183","display_name":"Canny edge detector","level":5,"score":0.5374731421470642},{"id":"https://openalex.org/C77017923","wikidata":"https://www.wikidata.org/wiki/Q912313","display_name":"Optical microscope","level":3,"score":0.4977588951587677},{"id":"https://openalex.org/C153180895","wikidata":"https://www.wikidata.org/wiki/Q7148389","display_name":"Pattern recognition (psychology)","level":2,"score":0.41439956426620483},{"id":"https://openalex.org/C120665830","wikidata":"https://www.wikidata.org/wiki/Q14620","display_name":"Optics","level":1,"score":0.36321842670440674},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.33008265495300293},{"id":"https://openalex.org/C9417928","wikidata":"https://www.wikidata.org/wiki/Q1070689","display_name":"Image processing","level":3,"score":0.2998596429824829},{"id":"https://openalex.org/C115961682","wikidata":"https://www.wikidata.org/wiki/Q860623","display_name":"Image (mathematics)","level":2,"score":0.22642195224761963},{"id":"https://openalex.org/C33923547","wikidata":"https://www.wikidata.org/wiki/Q395","display_name":"Mathematics","level":0,"score":0.1951003074645996},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.1678805649280548},{"id":"https://openalex.org/C26771246","wikidata":"https://www.wikidata.org/wiki/Q321095","display_name":"Scanning electron microscope","level":2,"score":0.08858326077461243},{"id":"https://openalex.org/C76155785","wikidata":"https://www.wikidata.org/wiki/Q418","display_name":"Telecommunications","level":1,"score":0.0},{"id":"https://openalex.org/C2524010","wikidata":"https://www.wikidata.org/wiki/Q8087","display_name":"Geometry","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1109/isbi.2015.7164152","doi":"https://doi.org/10.1109/isbi.2015.7164152","is_oa":false,"landing_page_url":"https://doi.org/10.1109/isbi.2015.7164152","pdf_url":null,"source":{"id":"https://openalex.org/S4363605129","display_name":"IEEE International Symposium on Biomedical Imaging (ISBI)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"conference"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"2015 IEEE 12th International Symposium on Biomedical Imaging (ISBI)","raw_type":"proceedings-article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":9,"referenced_works":["https://openalex.org/W1972175688","https://openalex.org/W2054804336","https://openalex.org/W2083374768","https://openalex.org/W2110158442","https://openalex.org/W2119823327","https://openalex.org/W2145023731","https://openalex.org/W2165914352","https://openalex.org/W2167279371","https://openalex.org/W3017143921"],"related_works":["https://openalex.org/W2069636820","https://openalex.org/W2082345152","https://openalex.org/W2125069876","https://openalex.org/W1970157989","https://openalex.org/W3108124507","https://openalex.org/W2558682519","https://openalex.org/W4240533049","https://openalex.org/W7098930120","https://openalex.org/W2060042886","https://openalex.org/W1972175688"],"abstract_inverted_index":{"Inspired":[0],"by":[1,73],"a":[2,53],"state":[3],"of":[4,22,34,48,63,68],"the":[5,20,49,59,64,69],"art":[6],"2D":[7],"algorithm":[8,75],"for":[9,29],"edge":[10,27,55,70,80],"detection":[11],"in":[12,15],"natural":[13],"images,":[14],"this":[16],"work":[17],"we":[18],"report":[19],"development":[21],"an":[23],"accurate":[24],"3D":[25,86],"probabilistic":[26,54],"detector":[28],"fluorescence":[30],"optical":[31],"microscopy":[32],"images":[33],"tissue":[35],"samples.":[36],"The":[37],"method":[38],"utilizes":[39],"multi-orientation":[40],"and":[41,45,61,76,84],"multi-scale":[42],"brightness,":[43],"textural":[44],"spectral":[46],"properties":[47],"data":[50],"to":[51],"compute":[52],"map.":[56],"To":[57],"demonstrate":[58],"strengths":[60],"accuracy":[62],"proposed":[65],"algorithm,":[66],"comparisons":[67],"maps":[71],"produced":[72],"our":[74],"several":[77],"other":[78],"popular":[79],"detectors":[81],"on":[82],"simulated":[83],"real":[85],"microscopic":[87],"volumes":[88],"are":[89],"provided.":[90]},"counts_by_year":[],"updated_date":"2026-10-27T15:51:10.671819","created_date":"2016-06-24T00:00:00"}