{"id":"https://openalex.org/W1513856479","doi":"https://doi.org/10.1186/s13014-015-0427-3","title":"BRCC3 acts as a prognostic marker in nasopharyngeal carcinoma patients treated with radiotherapy and mediates radiation resistance in vitro","display_name":"BRCC3 acts as a prognostic marker in nasopharyngeal carcinoma patients treated with radiotherapy and mediates radiation resistance in vitro","publication_year":2015,"publication_date":"2015-05-29","ids":{"openalex":"https://openalex.org/W1513856479","doi":"https://doi.org/10.1186/s13014-015-0427-3","mag":"1513856479","pmid":"https://pubmed.ncbi.nlm.nih.gov/26024915"},"language":"en","primary_location":{"id":"doi:10.1186/s13014-015-0427-3","doi":"https://doi.org/10.1186/s13014-015-0427-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13014-015-0427-3","pdf_url":"https://ro-journal.biomedcentral.com/counter/pdf/10.1186/s13014-015-0427-3","source":{"id":"https://openalex.org/S42123126","display_name":"Radiation Oncology","issn_l":"1748-717X","issn":["1748-717X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiation Oncology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://ro-journal.biomedcentral.com/counter/pdf/10.1186/s13014-015-0427-3","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060917804","display_name":"Ziwei Tu","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Ziwei Tu","raw_affiliation_strings":["Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China. tuzw@sysucc.org.cn","State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China. tuzw@sysucc.org.cn","Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China. tuzw@sysucc.org.cn","institution_ids":["https://openalex.org/I4210146711"]},{"raw_affiliation_string":"State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China. tuzw@sysucc.org.cn","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]},{"raw_affiliation_string":"Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China","institution_ids":["https://openalex.org/I4210146711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108657074","display_name":"Bingqing Xu","orcid":"https://orcid.org/0000-0002-7666-8635","observed_orcids":["https://orcid.org/0000-0002-7666-8635"]},"institutions":[{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Bingqing Xu","raw_affiliation_strings":["Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China. 756166607@qq.com","State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China. 756166607@qq.com","Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China. 756166607@qq.com","institution_ids":["https://openalex.org/I4210146711"]},{"raw_affiliation_string":"State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China. 756166607@qq.com","institution_ids":["https://openalex.org/I4210146711","https://openalex.org/I4391768007"]},{"raw_affiliation_string":"Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China","institution_ids":["https://openalex.org/I4210146711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085119245","display_name":"Chen Qu","orcid":"https://orcid.org/0000-0002-6539-3197","observed_orcids":["https://orcid.org/0000-0002-6539-3197"]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chen Qu","raw_affiliation_strings":["Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China. quchen@sysucc.org.cn","State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China. quchen@sysucc.org.cn","Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China. quchen@sysucc.org.cn","institution_ids":["https://openalex.org/I4210146711"]},{"raw_affiliation_string":"State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China. quchen@sysucc.org.cn","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]},{"raw_affiliation_string":"Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China","institution_ids":["https://openalex.org/I4210146711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113696143","display_name":"Yalan Tao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yalan Tao","raw_affiliation_strings":["Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China. taoyl@sysucc.org.cn","State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China. taoyl@sysucc.org.cn","Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China. taoyl@sysucc.org.cn","institution_ids":["https://openalex.org/I4210146711"]},{"raw_affiliation_string":"State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China. taoyl@sysucc.org.cn","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]},{"raw_affiliation_string":"Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China","institution_ids":["https://openalex.org/I4210146711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100418497","display_name":"Chen Chen","orcid":"https://orcid.org/0000-0002-8303-2862","observed_orcids":["https://orcid.org/0000-0002-8303-2862"]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Chen Chen","raw_affiliation_strings":["Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China. chenchen@sysucc.org.cn","State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China. chenchen@sysucc.org.cn","Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China. chenchen@sysucc.org.cn","institution_ids":["https://openalex.org/I4210146711"]},{"raw_affiliation_string":"State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China. chenchen@sysucc.org.cn","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]},{"raw_affiliation_string":"Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China","institution_ids":["https://openalex.org/I4210146711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051018135","display_name":"Wenfeng Hua","orcid":"https://orcid.org/0000-0002-2300-6427","observed_orcids":["https://orcid.org/0000-0002-2300-6427"]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wenfeng Hua","raw_affiliation_strings":["State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China. huawf@sysucc.org.cn","State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China. huawf@sysucc.org.cn","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]},{"raw_affiliation_string":"State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China","institution_ids":["https://openalex.org/I4210146711","https://openalex.org/I4391768007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016236030","display_name":"Guo\u2010Kai Feng","orcid":"https://orcid.org/0000-0002-8251-291X","observed_orcids":["https://orcid.org/0000-0002-8251-291X"]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guokai Feng","raw_affiliation_strings":["State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China. fenggk@sysucc.org.cn","State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China. fenggk@sysucc.org.cn","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]},{"raw_affiliation_string":"State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China","institution_ids":["https://openalex.org/I4210146711","https://openalex.org/I4391768007"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103138627","display_name":"Hui Chang","orcid":"https://orcid.org/0000-0001-6651-5101","observed_orcids":["https://orcid.org/0000-0001-6651-5101"]},"institutions":[{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Hui Chang","raw_affiliation_strings":["Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China. changhui@sysucc.org.cn","Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China. changhui@sysucc.org.cn","institution_ids":["https://openalex.org/I4210146711"]},{"raw_affiliation_string":"Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China","institution_ids":["https://openalex.org/I4210146711"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100398401","display_name":"Zhigang Liu","orcid":"https://orcid.org/0000-0002-1363-6708","observed_orcids":["https://orcid.org/0000-0002-1363-6708"]},"institutions":[{"id":"https://openalex.org/I139660479","display_name":"Central South University","ror":"https://ror.org/00f1zfq44","country_code":"CN","type":"education","lineage":["https://openalex.org/I139660479"]},{"id":"https://openalex.org/I4210115624","display_name":"Hunan Cancer Hospital","ror":"https://ror.org/025020z88","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210115624"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zhigang Liu","raw_affiliation_strings":["Department of Radiation Oncology, Hunan Cancer Hospital, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan, People's Republic of China. 85172626@qq.com","Department of Radiation Oncology, Hunan Cancer Hospital, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Hunan Cancer Hospital, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan, People's Republic of China. 85172626@qq.com","institution_ids":["https://openalex.org/I139660479","https://openalex.org/I4210115624"]},{"raw_affiliation_string":"Department of Radiation Oncology, Hunan Cancer Hospital, The Affiliated Cancer Hospital of Xiangya School of Medicine, Central South University, Changsha, Hunan, People's Republic of China","institution_ids":["https://openalex.org/I139660479","https://openalex.org/I4210115624"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101518895","display_name":"Li Guo","orcid":"https://orcid.org/0000-0002-4236-1264","observed_orcids":["https://orcid.org/0000-0002-4236-1264"]},"institutions":[{"id":"https://openalex.org/I4210153921","display_name":"Guangzhou Medical University Cancer Hospital","ror":"https://ror.org/046c18a90","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210153921"]},{"id":"https://openalex.org/I92039509","display_name":"Guangzhou Medical University","ror":"https://ror.org/00zat6v61","country_code":"CN","type":"education","lineage":["https://openalex.org/I92039509"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Guo Li","raw_affiliation_strings":["Department of Radiation Oncology, Affiliated Tumor Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China. 363905553@qq.com","Department of Radiation Oncology, Affiliated Tumor Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Affiliated Tumor Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China. 363905553@qq.com","institution_ids":["https://openalex.org/I4210153921","https://openalex.org/I92039509"]},{"raw_affiliation_string":"Department of Radiation Oncology, Affiliated Tumor Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China","institution_ids":["https://openalex.org/I92039509"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108087430","display_name":"Changbin Jiang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210098361","display_name":"First Affiliated Hospital of Guangzhou Medical University","ror":"https://ror.org/00z0j0d77","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210098361"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Changbin Jiang","raw_affiliation_strings":["Department of Radiation Oncology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China. 124915655@qq.com","Department of Radiation Oncology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China. 124915655@qq.com","institution_ids":["https://openalex.org/I4210098361"]},{"raw_affiliation_string":"Department of Radiation Oncology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China","institution_ids":["https://openalex.org/I4210098361"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089622171","display_name":"Wei Yi","orcid":"https://orcid.org/0000-0002-4349-910X","observed_orcids":["https://orcid.org/0000-0002-4349-910X"]},"institutions":[{"id":"https://openalex.org/I4210098361","display_name":"First Affiliated Hospital of Guangzhou Medical University","ror":"https://ror.org/00z0j0d77","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210098361"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Wei Yi","raw_affiliation_strings":["Department of Radiation Oncology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China. 897447290@qq.com","Department of Radiation Oncology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China. 897447290@qq.com","institution_ids":["https://openalex.org/I4210098361"]},{"raw_affiliation_string":"Department of Radiation Oncology, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, People's Republic of China","institution_ids":["https://openalex.org/I4210098361"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072945901","display_name":"Mu\u2010Sheng Zeng","orcid":"https://orcid.org/0000-0003-3509-5591","observed_orcids":["https://orcid.org/0000-0003-3509-5591","https://orcid.org/0000-0002-5410-2366"]},"institutions":[{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Musheng Zeng","raw_affiliation_strings":["State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China. zengmsh@sysucc.org.cn","State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China. zengmsh@sysucc.org.cn","institution_ids":["https://openalex.org/I4210146711","https://openalex.org/I4391768007"]},{"raw_affiliation_string":"State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China","institution_ids":["https://openalex.org/I4210146711","https://openalex.org/I4391768007"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102016054","display_name":"Yunfei Xia","orcid":"https://orcid.org/0000-0002-9515-2693","observed_orcids":["https://orcid.org/0000-0002-9515-2693"]},"institutions":[{"id":"https://openalex.org/I157773358","display_name":"Sun Yat-sen University","ror":"https://ror.org/0064kty71","country_code":"CN","type":"education","lineage":["https://openalex.org/I157773358"]},{"id":"https://openalex.org/I4210146711","display_name":"Sun Yat-sen University Cancer Center","ror":"https://ror.org/0400g8r85","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210146711"]},{"id":"https://openalex.org/I4391768007","display_name":"State Key Laboratory of Oncology in South China","ror":"https://ror.org/04dn2ax39","country_code":null,"type":"facility","lineage":["https://openalex.org/I157773358","https://openalex.org/I4391768007"]}],"countries":["CN"],"is_corresponding":true,"raw_author_name":"Yunfei Xia","raw_affiliation_strings":["Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China. xiayf@sysucc.org.cn","State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China. xiayf@sysucc.org.cn","State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiation Oncology, Sun Yat-Sen University Cancer Center, No. 651, Dongfeng East Road, Guangzhou, 510060, People's Republic of China. xiayf@sysucc.org.cn","institution_ids":["https://openalex.org/I4210146711"]},{"raw_affiliation_string":"State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China. xiayf@sysucc.org.cn","institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"]},{"raw_affiliation_string":"State Key Laboratory of Oncology in South China, Sun Yat-Sen University Cancer Center, Guangzhou, Guangdong, People's Republic of China","institution_ids":["https://openalex.org/I4210146711","https://openalex.org/I4391768007"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":8,"corresponding_author_ids":["https://openalex.org/A5102016054"],"corresponding_institution_ids":["https://openalex.org/I157773358","https://openalex.org/I4210146711","https://openalex.org/I4391768007"],"apc_list":{"value":3290,"currency":"USD","value_usd":3290},"apc_paid":{"value":3290,"currency":"USD","value_usd":3290},"fwci":2.6551,"has_fulltext":true,"cited_by_count":33,"citation_normalized_percentile":{"value":0.89050117,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":94,"max":98},"biblio":{"volume":"10","issue":"1","first_page":"123","last_page":"123"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10307","display_name":"Head and Neck Cancer Studies","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10123","display_name":"DNA Repair Mechanisms","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11176","display_name":"Radiation Therapy and Dosimetry","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2740","display_name":"Pulmonary and Respiratory Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/brcc3","display_name":"BRCC3","score":1.0},{"id":"https://openalex.org/keywords/nasopharyngeal-carcinoma","display_name":"nasopharyngeal carcinoma","score":0.9980000257492065},{"id":"https://openalex.org/keywords/prognostic-factors","display_name":"prognostic factors","score":0.9399999976158142},{"id":"https://openalex.org/keywords/radioresistance-biology","display_name":"radioresistance (biology)","score":0.9240000247955322},{"id":"https://openalex.org/keywords/radiotherapy","display_name":"radiotherapy","score":0.6840000152587891},{"id":"https://openalex.org/keywords/dna-repair","display_name":"DNA repair","score":0.9629999995231628},{"id":"https://openalex.org/keywords/g2-m-cell-cycle-arrest","display_name":"G2/M cell cycle arrest","score":0.9580000042915344},{"id":"https://openalex.org/keywords/overall-survival","display_name":"overall survival","score":0.6620000004768372},{"id":"https://openalex.org/keywords/locoregional-recurrence","display_name":"locoregional recurrence","score":0.7250000238418579},{"id":"https://openalex.org/keywords/clonogenic-survival","display_name":"clonogenic survival","score":0.6420000195503235}],"concepts":[{"id":"https://openalex.org/C2778997737","wikidata":"https://www.wikidata.org/wiki/Q1693598","display_name":"Nasopharyngeal carcinoma","level":3,"score":0.9699113368988037},{"id":"https://openalex.org/C58962609","wikidata":"https://www.wikidata.org/wiki/Q2353022","display_name":"Radioresistance","level":3,"score":0.8849964737892151},{"id":"https://openalex.org/C206684579","wikidata":"https://www.wikidata.org/wiki/Q4387689","display_name":"Radiosensitivity","level":3,"score":0.7471773624420166},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7425037622451782},{"id":"https://openalex.org/C509974204","wikidata":"https://www.wikidata.org/wiki/Q180507","display_name":"Radiation therapy","level":2,"score":0.6065030097961426},{"id":"https://openalex.org/C173396325","wikidata":"https://www.wikidata.org/wiki/Q1501275","display_name":"Gene knockdown","level":3,"score":0.5964078903198242},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5808961391448975},{"id":"https://openalex.org/C29537977","wikidata":"https://www.wikidata.org/wiki/Q188941","display_name":"Cell cycle","level":3,"score":0.5365654826164246},{"id":"https://openalex.org/C143425029","wikidata":"https://www.wikidata.org/wiki/Q5205747","display_name":"DNA damage","level":3,"score":0.4925259053707123},{"id":"https://openalex.org/C2777546739","wikidata":"https://www.wikidata.org/wiki/Q33525","display_name":"Carcinoma","level":2,"score":0.4905475974082947},{"id":"https://openalex.org/C143998085","wikidata":"https://www.wikidata.org/wiki/Q162555","display_name":"Oncology","level":1,"score":0.4838341772556305},{"id":"https://openalex.org/C134935766","wikidata":"https://www.wikidata.org/wiki/Q210538","display_name":"DNA repair","level":3,"score":0.4594901204109192},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.403107613325119},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3531684875488281},{"id":"https://openalex.org/C81885089","wikidata":"https://www.wikidata.org/wiki/Q189082","display_name":"Cell culture","level":2,"score":0.3089406490325928},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.30641576647758484},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.18673089146614075},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.10542255640029907},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000072017","descriptor_name":"Deubiquitinating Enzymes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000072017","descriptor_name":"Deubiquitinating Enzymes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000072017","descriptor_name":"Deubiquitinating Enzymes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002277","descriptor_name":"Carcinoma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002277","descriptor_name":"Carcinoma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002277","descriptor_name":"Carcinoma","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D002277","descriptor_name":"Carcinoma","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D002277","descriptor_name":"Carcinoma","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D002277","descriptor_name":"Carcinoma","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D002277","descriptor_name":"Carcinoma","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":false},{"descriptor_ui":"D002277","descriptor_name":"Carcinoma","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":false},{"descriptor_ui":"D002277","descriptor_name":"Carcinoma","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":false},{"descriptor_ui":"D002277","descriptor_name":"Carcinoma","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002277","descriptor_name":"Carcinoma","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D002277","descriptor_name":"Carcinoma","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D004249","descriptor_name":"DNA Damage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004249","descriptor_name":"DNA Damage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004249","descriptor_name":"DNA Damage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004260","descriptor_name":"DNA Repair","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004260","descriptor_name":"DNA Repair","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004260","descriptor_name":"DNA Repair","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008565","descriptor_name":"Membrane Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009303","descriptor_name":"Nasopharyngeal Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009303","descriptor_name":"Nasopharyngeal Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009303","descriptor_name":"Nasopharyngeal Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009303","descriptor_name":"Nasopharyngeal Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D009303","descriptor_name":"Nasopharyngeal Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D009303","descriptor_name":"Nasopharyngeal Neoplasms","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D009303","descriptor_name":"Nasopharyngeal Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":false},{"descriptor_ui":"D009303","descriptor_name":"Nasopharyngeal Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":false},{"descriptor_ui":"D009303","descriptor_name":"Nasopharyngeal Neoplasms","qualifier_ui":"Q000532","qualifier_name":"radiotherapy","is_major_topic":false},{"descriptor_ui":"D009303","descriptor_name":"Nasopharyngeal Neoplasms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D009303","descriptor_name":"Nasopharyngeal Neoplasms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D009303","descriptor_name":"Nasopharyngeal Neoplasms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000037","qualifier_name":"antagonists & inhibitors","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D009363","descriptor_name":"Neoplasm Proteins","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011379","descriptor_name":"Prognosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011836","descriptor_name":"Radiation Tolerance","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011836","descriptor_name":"Radiation Tolerance","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011836","descriptor_name":"Radiation Tolerance","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014407","descriptor_name":"Tumor Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014407","descriptor_name":"Tumor Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014407","descriptor_name":"Tumor Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D014408","descriptor_name":"Biomarkers, Tumor","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D014410","descriptor_name":"Tumor Stem Cell Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014410","descriptor_name":"Tumor Stem Cell Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014410","descriptor_name":"Tumor Stem Cell Assay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015972","descriptor_name":"Gene Expression Regulation, Neoplastic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018572","descriptor_name":"Disease-Free Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018572","descriptor_name":"Disease-Free Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018572","descriptor_name":"Disease-Free Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D034622","descriptor_name":"RNA Interference","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D034622","descriptor_name":"RNA Interference","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D034622","descriptor_name":"RNA Interference","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D034741","descriptor_name":"RNA, Small Interfering","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D034741","descriptor_name":"RNA, Small Interfering","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D034741","descriptor_name":"RNA, Small Interfering","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D053208","descriptor_name":"Kaplan-Meier Estimate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053208","descriptor_name":"Kaplan-Meier Estimate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053208","descriptor_name":"Kaplan-Meier Estimate","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058990","descriptor_name":"Molecular Targeted Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058990","descriptor_name":"Molecular Targeted Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058990","descriptor_name":"Molecular Targeted Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059565","descriptor_name":"G2 Phase Cell Cycle Checkpoints","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059565","descriptor_name":"G2 Phase Cell Cycle Checkpoints","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D059565","descriptor_name":"G2 Phase Cell Cycle Checkpoints","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1186/s13014-015-0427-3","doi":"https://doi.org/10.1186/s13014-015-0427-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13014-015-0427-3","pdf_url":"https://ro-journal.biomedcentral.com/counter/pdf/10.1186/s13014-015-0427-3","source":{"id":"https://openalex.org/S42123126","display_name":"Radiation Oncology","issn_l":"1748-717X","issn":["1748-717X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiation Oncology","raw_type":"journal-article"},{"id":"pmid:26024915","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26024915","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiation oncology (London, England)","raw_type":"Journal Article"},{"id":"pmh:oai:pubmedcentral.nih.gov:4511524","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4511524","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Radiat Oncol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.1186/s13014-015-0427-3","doi":"https://doi.org/10.1186/s13014-015-0427-3","is_oa":true,"landing_page_url":"https://doi.org/10.1186/s13014-015-0427-3","pdf_url":"https://ro-journal.biomedcentral.com/counter/pdf/10.1186/s13014-015-0427-3","source":{"id":"https://openalex.org/S42123126","display_name":"Radiation Oncology","issn_l":"1748-717X","issn":["1748-717X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-b","doyens","jufo-1","ki-jl-1","medline","norway-1","poland-100","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Radiation Oncology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.550000011920929}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2964049696","display_name":"\u9f3b\u54bd\u764c\u653e\u5c04\u6cbb\u7597\u5206\u578b\u5206\u5b50\u6807\u5fd7\u7269\u529f\u80fd\u4e0e\u673a\u5236","funder_award_id":"31170805","funder_id":"https://openalex.org/F4320321001","funder_display_name":"National Natural Science Foundation of China"}],"funders":[{"id":"https://openalex.org/F4320321001","display_name":"National Natural Science Foundation of China","ror":"https://ror.org/01h0zpd94"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1513856479.pdf","grobid_xml":"https://content.openalex.org/works/W1513856479.grobid-xml"},"referenced_works_count":39,"referenced_works":["https://openalex.org/W1576811559","https://openalex.org/W1961425141","https://openalex.org/W1965421847","https://openalex.org/W1973030224","https://openalex.org/W1973395384","https://openalex.org/W1974755980","https://openalex.org/W1982634724","https://openalex.org/W1990365150","https://openalex.org/W1998499862","https://openalex.org/W2000285763","https://openalex.org/W2004008931","https://openalex.org/W2010845229","https://openalex.org/W2013996063","https://openalex.org/W2014895093","https://openalex.org/W2015807143","https://openalex.org/W2058471321","https://openalex.org/W2059426385","https://openalex.org/W2066787077","https://openalex.org/W2072150230","https://openalex.org/W2074908827","https://openalex.org/W2081983124","https://openalex.org/W2084969545","https://openalex.org/W2089827566","https://openalex.org/W2102872615","https://openalex.org/W2106687310","https://openalex.org/W2109716976","https://openalex.org/W2114119309","https://openalex.org/W2116905005","https://openalex.org/W2121179939","https://openalex.org/W2128844816","https://openalex.org/W2128985829","https://openalex.org/W2133155105","https://openalex.org/W2142757721","https://openalex.org/W2147344015","https://openalex.org/W2152440925","https://openalex.org/W2154745425","https://openalex.org/W2163563958","https://openalex.org/W3142209824","https://openalex.org/W4390458881"],"related_works":["https://openalex.org/W2354788341","https://openalex.org/W3192539705","https://openalex.org/W2108792373","https://openalex.org/W2276492661","https://openalex.org/W2393812134","https://openalex.org/W2148139264","https://openalex.org/W2031285384","https://openalex.org/W3029103672","https://openalex.org/W2353018140","https://openalex.org/W2348275652"],"abstract_inverted_index":{"BACKGROUND:":[0],"BRCC3":[1,21,35,53,71,92,119,132,147,170,181,197],"has":[2],"been":[3],"found":[4],"to":[5,22,50],"be":[6],"aberrantly":[7],"expressed":[8],"in":[9,14,39,136,142,159,164,172,187],"breast":[10],"tumors":[11],"and":[12,26,44,64,82,107,157,202],"involved":[13],"DNA":[15,79,154],"damage":[16,80,155],"response.":[17],"The":[18,91,129],"contribution":[19],"of":[20,34,55,70,131,146,196],"nasopharyngeal":[23,41,56,74,99,138,173,188,206],"carcinoma":[24,42,57,75,100,139,174,189],"prognosis":[25],"radiosensitivity":[27],"is":[28,176],"still":[29],"unclear.":[30],"METHODS:":[31],"Immunohistochemical":[32],"analysis":[33,116],"was":[36,48,60,88,95,121,133],"carried":[37],"out":[38],"100":[40],"tissues,":[43],"the":[45,68,149,185,194],"protein":[46,93],"level":[47,94],"correlated":[49,97],"patient":[51,101],"survival.":[52,180],"expression":[54,120,130,171],"cell":[58,76,83,150,161],"lines":[59],"determined":[61],"by":[62],"Western-blotting":[63],"real-time":[65],"PCR.":[66],"Additionally,":[67],"effects":[69],"knockdown":[72,182],"on":[73],"clongenic":[77],"survival,":[78],"repair,":[81],"cycle":[84,162],"distribution":[85],"after":[86],"irradiation":[87],"assessed.":[89],"RESULTS:":[90],"inversely":[96],"with":[98,178],"overall":[102],"survival":[103,111,151],"(P":[104,112,126],"<":[105],"0.001)":[106],"3-year":[108],"loco-regional":[109],"relapse-free":[110],"=":[113,127],"0.034).":[114],"Multivariate":[115],"demonstrated":[117],"that":[118],"an":[122],"independent":[123],"prognostic":[124,200],"factor":[125],"0.010).":[128],"much":[134],"higher":[135],"radioresistant":[137,165],"cells":[140],"than":[141],"radiosensitive":[143],"cells.":[144,167,190],"Knockdown":[145],"increased":[148],"fraction,":[152],"attenuated":[153],"repair":[156],"resulted":[158],"G2/M":[160],"arrest":[163],"NPC":[166],"CONCLUSIONS:":[168],"High":[169],"patients":[175],"associated":[177],"poor":[179],"could":[183],"abate":[184],"radioresistance":[186],"These":[191],"findings":[192],"suggest":[193],"utility":[195],"as":[198],"a":[199],"biomarker":[201],"novel":[203],"target":[204],"for":[205],"carcinoma.":[207]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":4},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":3}],"updated_date":"2026-10-16T09:59:22.235173","created_date":"2016-06-24T00:00:00"}