{"id":"https://openalex.org/W1509561325","doi":"https://doi.org/10.1016/s0091-679x(04)77018-1","title":"Lessons from Transgenic Zebrafish Expressing the Green Fluorescent Protein (GFP) in the Myeloid Lineage","display_name":"Lessons from Transgenic Zebrafish Expressing the Green Fluorescent Protein (GFP) in the Myeloid Lineage","publication_year":2004,"publication_date":"2004-01-01","ids":{"openalex":"https://openalex.org/W1509561325","doi":"https://doi.org/10.1016/s0091-679x(04)77018-1","mag":"1509561325","pmid":"https://pubmed.ncbi.nlm.nih.gov/15602920"},"language":"en","primary_location":{"id":"doi:10.1016/s0091-679x(04)77018-1","doi":"https://doi.org/10.1016/s0091-679x(04)77018-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0091-679x(04)77018-1","pdf_url":null,"source":{"id":"https://openalex.org/S177811526","display_name":"Methods in cell biology","issn_l":"0091-679X","issn":["0091-679X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in Cell Biology","raw_type":"book-chapter"},"volume":null,"type":"book-chapter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072906560","display_name":"Karl Hsu","orcid":"https://orcid.org/0000-0003-3137-1202","observed_orcids":["https://orcid.org/0000-0003-3137-1202"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karl Hsu","raw_affiliation_strings":["Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, Massachusetts 02115, USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085803011","display_name":"Alfred Thomas Look","orcid":"https://orcid.org/0000-0001-7851-8617","observed_orcids":["https://orcid.org/0000-0001-7851-8617","https://orcid.org/0000-0001-5410-6220"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A.Thomas Look","raw_affiliation_strings":["Department of Pediatric Oncology Dana-Farber Cancer Institute Harvard Medical School Boston, Massachusetts 02115 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric Oncology Dana-Farber Cancer Institute Harvard Medical School Boston, Massachusetts 02115 USA","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004943053","display_name":"John P. Kanki","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John P. Kanki","raw_affiliation_strings":["Division of Hematology\u29f8Oncology Beth Israel Deaconess Medical Center Harvard Medical School Boston, Massachusetts 02115 USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Hematology\u29f8Oncology Beth Israel Deaconess Medical Center Harvard Medical School Boston, Massachusetts 02115 USA","institution_ids":["https://openalex.org/I1316535847","https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.08823529,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":96},"biblio":{"volume":"77","issue":null,"first_page":"333","last_page":"347"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11685","display_name":"Zebrafish Biomedical Research Applications","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11685","display_name":"Zebrafish Biomedical Research Applications","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10268","display_name":"Developmental Biology and Gene Regulation","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10345","display_name":"Hematopoietic Stem Cell Transplantation","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transgenic-zebrafish","display_name":"transgenic zebrafish","score":0.9490000009536743},{"id":"https://openalex.org/keywords/green-fluorescent-protein","display_name":"green fluorescent protein","score":0.9490000009536743},{"id":"https://openalex.org/keywords/myeloid-differentiation","display_name":"myeloid differentiation","score":0.8930000066757202},{"id":"https://openalex.org/keywords/hematopoiesis","display_name":"hematopoiesis","score":0.953000009059906},{"id":"https://openalex.org/keywords/hematopoietic-stem-cells","display_name":"hematopoietic stem cells","score":0.7839999794960022},{"id":"https://openalex.org/keywords/lineage-determination","display_name":"lineage determination","score":0.6669999957084656},{"id":"https://openalex.org/keywords/cell-tracking","display_name":"cell tracking","score":0.5400000214576721},{"id":"https://openalex.org/keywords/myelopoiesis","display_name":"myelopoiesis","score":0.7580000162124634},{"id":"https://openalex.org/keywords/ets-transcription-factors","display_name":"ETS transcription factors","score":0.6620000004768372},{"id":"https://openalex.org/keywords/granulocytes","display_name":"granulocytes","score":0.6809999942779541},{"id":"https://openalex.org/keywords/monocytes-macrophages","display_name":"monocytes/macrophages","score":0.8309999704360962},{"id":"https://openalex.org/keywords/fluorescence-activated-cell-sorting","display_name":"fluorescence-activated cell sorting","score":0.6380000114440918},{"id":"https://openalex.org/keywords/hematopoietic-stem-cell-transplantation","display_name":"hematopoietic stem cell transplantation","score":0.675000011920929}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.9527791142463684},{"id":"https://openalex.org/C142613039","wikidata":"https://www.wikidata.org/wiki/Q272983","display_name":"Green fluorescent protein","level":3,"score":0.9427880644798279},{"id":"https://openalex.org/C2776878037","wikidata":"https://www.wikidata.org/wiki/Q169444","display_name":"Zebrafish","level":3,"score":0.817977786064148},{"id":"https://openalex.org/C102230213","wikidata":"https://www.wikidata.org/wiki/Q430117","display_name":"Transgene","level":3,"score":0.5726989507675171},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5533214211463928},{"id":"https://openalex.org/C2776817793","wikidata":"https://www.wikidata.org/wiki/Q6553369","display_name":"Lineage (genetic)","level":3,"score":0.5288915038108826},{"id":"https://openalex.org/C2994430510","wikidata":"https://www.wikidata.org/wiki/Q3270846","display_name":"Myeloid cells","level":3,"score":0.49475306272506714},{"id":"https://openalex.org/C3019336641","wikidata":"https://www.wikidata.org/wiki/Q55643886","display_name":"Fluorescent protein","level":4,"score":0.4680483043193817},{"id":"https://openalex.org/C2779282312","wikidata":"https://www.wikidata.org/wiki/Q1956561","display_name":"Myeloid","level":2,"score":0.3799792528152466},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.19150510430335999},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.17532122135162354},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.13707607984542847}],"mesh":[{"descriptor_ui":"D000099232","descriptor_name":"Proto-Oncogene Protein Spi-1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004625","descriptor_name":"Embryo, Nonmammalian","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D004625","descriptor_name":"Embryo, Nonmammalian","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D011401","descriptor_name":"Promoter Regions, Genetic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D011518","descriptor_name":"Proto-Oncogene Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014018","descriptor_name":"Tissue Distribution","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D015027","descriptor_name":"Zebrafish","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":false},{"descriptor_ui":"D015027","descriptor_name":"Zebrafish","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D015534","descriptor_name":"Trans-Activators","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D018014","descriptor_name":"Gene Transfer Techniques","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018507","descriptor_name":"Gene Expression Regulation, Developmental","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D019070","descriptor_name":"Cell Lineage","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D022423","descriptor_name":"Myeloid Cells","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D022423","descriptor_name":"Myeloid Cells","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D030801","descriptor_name":"Animals, Genetically Modified","qualifier_ui":"Q000196","qualifier_name":"embryology","is_major_topic":true},{"descriptor_ui":"D030801","descriptor_name":"Animals, Genetically Modified","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D049452","descriptor_name":"Green Fluorescent Proteins","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":true},{"descriptor_ui":"D049452","descriptor_name":"Green Fluorescent Proteins","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/s0091-679x(04)77018-1","doi":"https://doi.org/10.1016/s0091-679x(04)77018-1","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s0091-679x(04)77018-1","pdf_url":null,"source":{"id":"https://openalex.org/S177811526","display_name":"Methods in cell biology","issn_l":"0091-679X","issn":["0091-679X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in Cell Biology","raw_type":"book-chapter"},{"id":"pmid:15602920","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15602920","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Methods in cell biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G2524835416","display_name":null,"funder_award_id":"CA 96785","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G2946636155","display_name":null,"funder_award_id":"CA93152","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G3866319779","display_name":"Zebrafish Models of FLT3-mediated Myeloid Leukemias","funder_award_id":"K08CA096785","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G5544403951","display_name":null,"funder_award_id":"CA006516","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G863721443","display_name":"Genetic Basis of Myeloid Neoplasia--Mutagenesis Screens","funder_award_id":"R01CA093152","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000911608","display_name":"Dana-Farber/Harvard Cancer Center","funder_award_id":"P30CA006516","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320308295","display_name":"Leukemia and Lymphoma Society","ror":"https://ror.org/04m0xav37"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W43784428","https://openalex.org/W1483582136","https://openalex.org/W1508593718","https://openalex.org/W1526134400","https://openalex.org/W1576449915","https://openalex.org/W1828932747","https://openalex.org/W1933480341","https://openalex.org/W1998756807","https://openalex.org/W2005288945","https://openalex.org/W2007625577","https://openalex.org/W2017225353","https://openalex.org/W2025589527","https://openalex.org/W2026663073","https://openalex.org/W2048871822","https://openalex.org/W2061740109","https://openalex.org/W2065633957","https://openalex.org/W2083007873","https://openalex.org/W2089149683","https://openalex.org/W2090786449","https://openalex.org/W2113260405","https://openalex.org/W2115198211","https://openalex.org/W2121676856","https://openalex.org/W2123480703","https://openalex.org/W2132362370","https://openalex.org/W2137014806","https://openalex.org/W2140367720","https://openalex.org/W2146310502","https://openalex.org/W2151570316","https://openalex.org/W2184156621","https://openalex.org/W2411489146","https://openalex.org/W6601757200"],"related_works":["https://openalex.org/W2137014806","https://openalex.org/W7099021196","https://openalex.org/W2083007873","https://openalex.org/W2055004906","https://openalex.org/W1985753010","https://openalex.org/W1969630791","https://openalex.org/W1933480341","https://openalex.org/W2082942373","https://openalex.org/W6992062251","https://openalex.org/W1984253490"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}