{"id":"https://openalex.org/W15090599","doi":null,"title":"Beta-2 microglobulin serum levels in maintenance dialysis. What does it mean?","display_name":"Beta-2 microglobulin serum levels in maintenance dialysis. What does it mean?","publication_year":1988,"publication_date":"1988-10-01","ids":{"openalex":"https://openalex.org/W15090599","mag":"15090599","pmid":"https://pubmed.ncbi.nlm.nih.gov/3064791"},"language":"en","primary_location":{"id":"pmid:3064791","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3064791","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ASAIO transactions","raw_type":"Journal Article"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054201980","display_name":"Bernard Canaud","orcid":"https://orcid.org/0000-0001-6854-2816","observed_orcids":["https://orcid.org/0000-0001-6854-2816"]},"institutions":[{"id":"https://openalex.org/I4210132125","display_name":"H\u00f4pital Lapeyronie","ror":"https://ror.org/03xzagw65","country_code":"FR","type":"healthcare","lineage":["https://openalex.org/I4210093292","https://openalex.org/I4210132125"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"B Canaud","raw_affiliation_strings":["Department of Nephrology, Lapeyronie University Hospital, Montpellier, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Nephrology, Lapeyronie University Hospital, Montpellier, France","institution_ids":["https://openalex.org/I4210132125"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5051698668","display_name":"Alain Guy Honor\u00e9 Assounga","orcid":"https://orcid.org/0000-0003-4708-1509","observed_orcids":["https://orcid.org/0000-0003-4708-1509"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Assounga","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109921177","display_name":"Jean Louis Flavier","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"J L Flavier","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013516712","display_name":"Alain Slingeneyer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"A Slingeneyer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"R Aznar","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R Aznar","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020350252","display_name":"M Robinet-L\u00e9vy","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Robinet-Levy","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5080082788","display_name":"Ch. Mion","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"C Mion","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.2134,"has_fulltext":false,"cited_by_count":16,"citation_normalized_percentile":{"value":0.77306068,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":94},"biblio":{"volume":"34","issue":"4","first_page":"923","last_page":"9"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10291","display_name":"Dialysis and Renal Disease Management","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10516","display_name":"Parathyroid Disorders and Treatments","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10684","display_name":"Acute Kidney Injury Research","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2727","display_name":"Nephrology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/beta2-microglobulin","display_name":"beta2-microglobulin","score":0.9929999709129333},{"id":"https://openalex.org/keywords/maintenance-dialysis","display_name":"chronic dialysis","score":0.8650000095367432},{"id":"https://openalex.org/keywords/hemodialysis","display_name":"hemodialysis","score":0.7870000004768372},{"id":"https://openalex.org/keywords/peritoneal-dialysis","display_name":"peritoneal dialysis","score":0.9980000257492065},{"id":"https://openalex.org/keywords/continuous-ambulatory-peritoneal-dialysis","display_name":"continuous ambulatory peritoneal dialysis","score":0.953000009059906},{"id":"https://openalex.org/keywords/hemofiltration","display_name":"hemofiltration","score":0.8669999837875366},{"id":"https://openalex.org/keywords/hemodiafiltration","display_name":"hemodiafiltration","score":0.9179999828338623},{"id":"https://openalex.org/keywords/end-stage-renal-disease","display_name":"end-stage renal disease","score":0.8500000238418579},{"id":"https://openalex.org/keywords/amyloidosis","display_name":"amyloidosis","score":0.656000018119812},{"id":"https://openalex.org/keywords/dialysis-membrane-permeability","display_name":"dialysis membrane permeability","score":0.7360000014305115},{"id":"https://openalex.org/keywords/biocompatibility","display_name":"biocompatibility","score":0.7580000162124634},{"id":"https://openalex.org/keywords/residual-renal-function","display_name":"residual renal function","score":0.8659999966621399},{"id":"https://openalex.org/keywords/cancer","display_name":"cancer","score":0.328000009059906},{"id":"https://openalex.org/keywords/serum-protein-levels","display_name":"serum protein levels","score":0.5149999856948853}],"concepts":[{"id":"https://openalex.org/C21957315","wikidata":"https://www.wikidata.org/wiki/Q287896","display_name":"Beta-2 microglobulin","level":2,"score":0.7828196287155151},{"id":"https://openalex.org/C2776174256","wikidata":"https://www.wikidata.org/wiki/Q830842","display_name":"BETA (programming language)","level":2,"score":0.6258271932601929},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.61655193567276},{"id":"https://openalex.org/C2779056158","wikidata":"https://www.wikidata.org/wiki/Q1756474","display_name":"Peritoneal dialysis","level":2,"score":0.5138013958930969},{"id":"https://openalex.org/C126894567","wikidata":"https://www.wikidata.org/wiki/Q105650","display_name":"Urology","level":1,"score":0.4614526033401489},{"id":"https://openalex.org/C2778063415","wikidata":"https://www.wikidata.org/wiki/Q391744","display_name":"Hemodialysis","level":2,"score":0.4488992691040039},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4168008267879486},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3930444121360779},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001613","descriptor_name":"beta 2-Microglobulin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004231","descriptor_name":"Diuresis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005500","descriptor_name":"Follow-Up Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006435","descriptor_name":"Renal Dialysis","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D006440","descriptor_name":"Hemofiltration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010530","descriptor_name":"Peritoneal Dialysis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010531","descriptor_name":"Peritoneal Dialysis, Continuous Ambulatory","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:3064791","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3064791","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"ASAIO transactions","raw_type":"Journal Article"},{"id":"mag:15090599","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/3064791","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.98580002784729,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2396978922","https://openalex.org/W1993098199","https://openalex.org/W1967833556","https://openalex.org/W2343400212","https://openalex.org/W1999401895","https://openalex.org/W2022464858","https://openalex.org/W2415534744","https://openalex.org/W99891999","https://openalex.org/W56935082","https://openalex.org/W1489751648"],"abstract_inverted_index":{"beta-2":[0],"Microglobulin":[1],"levels":[2,197],"(beta-2M)":[3],"were":[4,40,75,88],"analyzed":[5],"at":[6,200],"four":[7],"month":[8],"intervals":[9],"in":[10,30,37,53,77,90,132,144,212,217],"sera":[11],"of":[12,18,106,136,198,203,236],"237":[13],"patients":[14,26,55,91,214],"on":[15,65],"various":[16,66],"forms":[17],"dialysis":[19,58],"over":[20],"a":[21,133,158,204],"2":[22,86,122,148],"year":[23],"period;":[24],"twelve":[25],"volunteered":[27],"to":[28,126,192,228,241],"participate":[29],"short-term":[31],"kinetics":[32],"studies.":[33],"Duplicate":[34],"beta-2M":[35,52,73,160,163,193,195,210],"measurements":[36],"biologic":[38],"fluids":[39],"performed":[41],"using":[42,237],"an":[43,63],"RIA":[44],"kit.":[45],"The":[46,99],"data":[47],"presented":[48],"confirm":[49],"elevated":[50],"serum":[51,70],"dialyzed":[54],"whatever":[56],"the":[57,127,201,230,233],"method":[59],"used":[60],"and":[61,113,150,175,183,221],"give":[62],"overview":[64],"factors":[67],"affecting":[68],"circulating":[69],"beta-2M.":[71],"Intraindividual":[72],"variations":[74],"13%":[76],"stable":[78],"ESRD":[79],"patients.":[80,138],"Unusually":[81],"high":[82,172],"values":[83],"(greater":[84],"than":[85],"SE)":[87],"observed":[89,103],"presenting":[92],"with":[93,194],"severe":[94],"intercurrent":[95],"disease":[96],"(e.g.,":[97],"cancer).":[98],"only":[100],"significant":[101,140],"difference":[102,141],"between":[104],"groups":[105],"patients,":[107,156],"HD":[108],"(46":[109],"+/-":[110,117,121,147,153],"1":[111],"mg/L)":[112,149,155],"PD":[114,137],"(IPD:":[115],"33":[116],"3,":[118],"CAPD:":[119],"37":[120],"mg/L),":[123],"was":[124,142],"due":[125],"residual":[128],"renal":[129],"function":[130],"preserved":[131],"higher":[134,159],"percentage":[135],"No":[139],"noted":[143],"HF":[145],"(40":[146],"HDF":[151],"(38":[152],"5":[154],"despite":[157],"removal":[161],"rate.":[162],"membrane":[164,188,240],"permeability":[165,220],"differs":[166],"greatly":[167],"among":[168],"filters.":[169],"It":[170],"is":[171,189,215,225],"for":[173,178,181,185],"AN69":[174],"Polysulfone,":[176],"intermediate":[177],"Polyamide,":[179],"low":[180],"Polyacrylonitrile":[182],"none":[184],"Cuprophane.":[186],"Peritoneal":[187],"highly":[190,238],"permeable":[191,239],"dialysate/serum":[196],"0.20":[199],"end":[202],"6":[205],"hr":[206],"exchange.":[207],"In":[208],"conclusion,":[209],"determination":[211],"uremic":[213],"useful":[216],"assessing":[218],"material":[219],"biocompatibility.":[222],"However,":[223],"it":[224],"too":[226],"early":[227],"determine":[229],"impact":[231],"or":[232],"beneficial":[234],"effects":[235],"prevent":[242],"beta-2M-amyloidosis":[243],"related":[244],"nonarticular":[245],"complications.":[246]},"counts_by_year":[{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}