{"id":"https://openalex.org/W1508933930","doi":"https://doi.org/10.14800/pm.745","title":"Functional Pseudogenes Inhibit The Superoxide Production","display_name":"Functional Pseudogenes Inhibit The Superoxide Production","publication_year":2015,"publication_date":"2015-10-27","ids":{"openalex":"https://openalex.org/W1508933930","doi":"https://doi.org/10.14800/pm.745","mag":"1508933930","pmid":"https://pubmed.ncbi.nlm.nih.gov/26086043","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4467915"},"language":"en","primary_location":{"id":"doi:10.14800/pm.745","doi":"https://doi.org/10.14800/pm.745","is_oa":false,"landing_page_url":"https://doi.org/10.14800/pm.745","pdf_url":null,"source":{"id":"https://openalex.org/S4210182360","display_name":"Precision Medicine","issn_l":"2377-9888","issn":["2377-9888"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310315843","host_organization_name":"Smart Science & Technology LLC, USA","host_organization_lineage":["https://openalex.org/P4310315843"],"host_organization_lineage_names":["Smart Science & Technology LLC, USA"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Precision Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4467915","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100700770","display_name":"Wei Xu","orcid":"https://orcid.org/0000-0002-9562-4697","observed_orcids":["https://orcid.org/0000-0002-9562-4697"]},"institutions":[{"id":"https://openalex.org/I4210121771","display_name":"First Affiliated Hospital of Xi'an Jiaotong University","ror":"https://ror.org/02tbvhh96","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210121771"]},{"id":"https://openalex.org/I6332465","display_name":"Morehouse School of Medicine","ror":"https://ror.org/01pbhra64","country_code":"US","type":"education","lineage":["https://openalex.org/I6332465"]},{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Wei Xu","raw_affiliation_strings":["Department of Cardiovascular Medicine, Key Laboratory of Molecular Cardiology, Cardiovascular Research Center, and Key Laboratory of Environment and Genes Related to Diseases, First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China ; Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia 30310, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Medicine, Key Laboratory of Molecular Cardiology, Cardiovascular Research Center, and Key Laboratory of Environment and Genes Related to Diseases, First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China ; Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia 30310, USA","institution_ids":["https://openalex.org/I4210121771","https://openalex.org/I6332465","https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Li Ma","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I6332465","display_name":"Morehouse School of Medicine","ror":"https://ror.org/01pbhra64","country_code":"US","type":"education","lineage":["https://openalex.org/I6332465"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Li Ma","raw_affiliation_strings":["Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia 30310, USA ; 4DGENOME Inc, Atlanta,Georgia 30092, GA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia 30310, USA ; 4DGENOME Inc, Atlanta,Georgia 30092, GA","institution_ids":["https://openalex.org/I6332465"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100327146","display_name":"Wenzhi Li","orcid":"https://orcid.org/0000-0002-5244-6333","observed_orcids":["https://orcid.org/0000-0002-5244-6333","https://orcid.org/0000-0002-6671-890X"]},"institutions":[{"id":"https://openalex.org/I6332465","display_name":"Morehouse School of Medicine","ror":"https://ror.org/01pbhra64","country_code":"US","type":"education","lineage":["https://openalex.org/I6332465"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Wenzhi Li","raw_affiliation_strings":["Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia 30310, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia 30310, USA","institution_ids":["https://openalex.org/I6332465"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035259707","display_name":"Tiffany Brunson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I6332465","display_name":"Morehouse School of Medicine","ror":"https://ror.org/01pbhra64","country_code":"US","type":"education","lineage":["https://openalex.org/I6332465"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tiffany A Brunson","raw_affiliation_strings":["Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia 30310, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia 30310, USA","institution_ids":["https://openalex.org/I6332465"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Xiaohua Tian","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I6332465","display_name":"Morehouse School of Medicine","ror":"https://ror.org/01pbhra64","country_code":"US","type":"education","lineage":["https://openalex.org/I6332465"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Xiaohua Tian","raw_affiliation_strings":["Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia 30310, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia 30310, USA","institution_ids":["https://openalex.org/I6332465"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5040132248","display_name":"Jendai C. Richards","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I6332465","display_name":"Morehouse School of Medicine","ror":"https://ror.org/01pbhra64","country_code":"US","type":"education","lineage":["https://openalex.org/I6332465"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jendai Richards","raw_affiliation_strings":["Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia 30310, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia 30310, USA","institution_ids":["https://openalex.org/I6332465"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5007309170","display_name":"Qiling Li","orcid":"https://orcid.org/0000-0003-3763-4456","observed_orcids":["https://orcid.org/0000-0003-3763-4456","https://orcid.org/0000-0001-9438-6765"]},"institutions":[{"id":"https://openalex.org/I4210121771","display_name":"First Affiliated Hospital of Xi'an Jiaotong University","ror":"https://ror.org/02tbvhh96","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210121771"]},{"id":"https://openalex.org/I6332465","display_name":"Morehouse School of Medicine","ror":"https://ror.org/01pbhra64","country_code":"US","type":"education","lineage":["https://openalex.org/I6332465"]},{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Qiling Li","raw_affiliation_strings":["Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia 30310, USA ; Department of Obstetrics and Gynecology, First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia 30310, USA ; Department of Obstetrics and Gynecology, First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China","institution_ids":["https://openalex.org/I4210121771","https://openalex.org/I6332465","https://openalex.org/I87445476"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036639269","display_name":"Tameka Bythwood","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I6332465","display_name":"Morehouse School of Medicine","ror":"https://ror.org/01pbhra64","country_code":"US","type":"education","lineage":["https://openalex.org/I6332465"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tameka Bythwood","raw_affiliation_strings":["Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia 30310, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia 30310, USA","institution_ids":["https://openalex.org/I6332465"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5100603166","display_name":"Zuyi Yuan","orcid":"https://orcid.org/0000-0002-4141-0298","observed_orcids":["https://orcid.org/0000-0002-4141-0298"]},"institutions":[{"id":"https://openalex.org/I4210121771","display_name":"First Affiliated Hospital of Xi'an Jiaotong University","ror":"https://ror.org/02tbvhh96","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210121771"]},{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Zuyi Yuan","raw_affiliation_strings":["Department of Cardiovascular Medicine, Key Laboratory of Molecular Cardiology, Cardiovascular Research Center, and Key Laboratory of Environment and Genes Related to Diseases, First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Medicine, Key Laboratory of Molecular Cardiology, Cardiovascular Research Center, and Key Laboratory of Environment and Genes Related to Diseases, First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China","institution_ids":["https://openalex.org/I4210121771","https://openalex.org/I87445476"]}]},{"author_position":"last","author":{"id":null,"display_name":"Qing Song","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210121771","display_name":"First Affiliated Hospital of Xi'an Jiaotong University","ror":"https://ror.org/02tbvhh96","country_code":"CN","type":"healthcare","lineage":["https://openalex.org/I4210121771"]},{"id":"https://openalex.org/I6332465","display_name":"Morehouse School of Medicine","ror":"https://ror.org/01pbhra64","country_code":"US","type":"education","lineage":["https://openalex.org/I6332465"]},{"id":"https://openalex.org/I87445476","display_name":"Xi'an Jiaotong University","ror":"https://ror.org/017zhmm22","country_code":"CN","type":"education","lineage":["https://openalex.org/I87445476"]}],"countries":["CN","US"],"is_corresponding":false,"raw_author_name":"Qing Song","raw_affiliation_strings":["Department of Cardiovascular Medicine, Key Laboratory of Molecular Cardiology, Cardiovascular Research Center, and Key Laboratory of Environment and Genes Related to Diseases, First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China ; Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia 30310, USA ; Department of Medicine, Morehouse School of Medicine, Atlanta, Georgia 30310, USA ; Department of Obstetrics and Gynecology, First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China ; 4DGENOME Inc, Atlanta,Georgia 30092, GA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Cardiovascular Medicine, Key Laboratory of Molecular Cardiology, Cardiovascular Research Center, and Key Laboratory of Environment and Genes Related to Diseases, First Affiliated Hospital of Medical School, Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China ; Cardiovascular Research Institute, Morehouse School of Medicine, Atlanta, Georgia 30310, USA ; Department of Medicine, Morehouse School of Medicine, Atlanta, Georgia 30310, USA ; Department of Obstetrics and Gynecology, First Affiliated Hospital, Xi'an Jiaotong University, Xi'an, 710061, Shaanxi, China ; 4DGENOME Inc, Atlanta,Georgia 30092, GA","institution_ids":["https://openalex.org/I4210121771","https://openalex.org/I6332465","https://openalex.org/I87445476"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.7098,"has_fulltext":false,"cited_by_count":6,"citation_normalized_percentile":{"value":0.69371931,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":95},"biblio":{"volume":"1","issue":"1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.22059999406337738,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10434","display_name":"Chromosomal and Genetic Variations","score":0.22059999406337738,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11597","display_name":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","score":0.1876000016927719,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11884","display_name":"Redox biology and oxidative stress","score":0.10100000351667404,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/superoxide-production","display_name":"superoxide production","score":0.8899999856948853},{"id":"https://openalex.org/keywords/alternative-splicing","display_name":"alternative splicing","score":0.7289999723434448},{"id":"https://openalex.org/keywords/splicing-isoforms","display_name":"splicing isoforms","score":0.9160000085830688},{"id":"https://openalex.org/keywords/copy-number-variation","display_name":"copy number variation","score":0.8619999885559082},{"id":"https://openalex.org/keywords/vascular-endothelial-cells","display_name":"vascular endothelial cells","score":0.8320000171661377},{"id":"https://openalex.org/keywords/cytoplasmic-protein-localization","display_name":"cytoplasmic protein localization","score":0.7720000147819519},{"id":"https://openalex.org/keywords/tissue-distribution","display_name":"tissue distribution","score":0.6890000104904175},{"id":"https://openalex.org/keywords/transcriptional-regulation","display_name":"transcriptional regulation","score":0.8500000238418579},{"id":"https://openalex.org/keywords/drug-discovery","display_name":"drug discovery","score":0.6800000071525574}],"concepts":[{"id":"https://openalex.org/C34957205","wikidata":"https://www.wikidata.org/wiki/Q277338","display_name":"Pseudogene","level":4,"score":0.9564006328582764},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7422285079956055},{"id":"https://openalex.org/C194583182","wikidata":"https://www.wikidata.org/wiki/Q21114084","display_name":"Alternative splicing","level":4,"score":0.5605984926223755},{"id":"https://openalex.org/C53345823","wikidata":"https://www.wikidata.org/wiki/Q5531554","display_name":"Gene isoform","level":3,"score":0.508995771408081},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.49064913392066956},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.47306525707244873},{"id":"https://openalex.org/C197077220","wikidata":"https://www.wikidata.org/wiki/Q720988","display_name":"Human genome","level":4,"score":0.4480021893978119},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.4445621967315674},{"id":"https://openalex.org/C54458228","wikidata":"https://www.wikidata.org/wiki/Q237218","display_name":"RNA splicing","level":4,"score":0.4399515390396118},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.4020254611968994},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.32385337352752686},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.19945335388183594}],"mesh":[],"locations_count":4,"locations":[{"id":"doi:10.14800/pm.745","doi":"https://doi.org/10.14800/pm.745","is_oa":false,"landing_page_url":"https://doi.org/10.14800/pm.745","pdf_url":null,"source":{"id":"https://openalex.org/S4210182360","display_name":"Precision Medicine","issn_l":"2377-9888","issn":["2377-9888"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310315843","host_organization_name":"Smart Science & Technology LLC, USA","host_organization_lineage":["https://openalex.org/P4310315843"],"host_organization_lineage_names":["Smart Science & Technology LLC, USA"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Precision Medicine","raw_type":"journal-article"},{"id":"pmid:26086043","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26086043","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Precision medicine","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:3430349","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4467915","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4467915","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4467915","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Precis Med","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:3430349","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4467915","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"score":0.8371999859809875,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1673703941","display_name":"Morehouse School of Medicine Center of Excellence Research Endowment Program","funder_award_id":"S21MD000101","funder_id":"https://openalex.org/F4320337534","funder_display_name":"National Institute on Minority Health and Health Disparities"},{"id":"https://openalex.org/G3389048470","display_name":"Determining the Phased Genome Sequences","funder_award_id":"R21HG006173","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"},{"id":"https://openalex.org/G4658142325","display_name":"Morehouse School of Medicine G12 Multidisciplinary Biomedical Research Center","funder_award_id":"G12RR003034","funder_id":"https://openalex.org/F4320337375","funder_display_name":"National Center for Research Resources"},{"id":"https://openalex.org/G5237979432","display_name":"Cost-effective and high-throughput chromosomal haplotyping","funder_award_id":"R43HG007621","funder_id":"https://openalex.org/F4320337348","funder_display_name":"National Human Genome Research Institute"},{"id":"https://openalex.org/G625505657","display_name":"Morehouse Cardiovascular Research Center of Excellence","funder_award_id":"P50HL117929","funder_id":"https://openalex.org/F4320337338","funder_display_name":"National Heart, Lung, and Blood Institute"},{"id":"https://openalex.org/G6947229810","display_name":"Morehouse School of Medicine G12 Multidisciplinary Biomedical Research Center","funder_award_id":"G12MD007602","funder_id":"https://openalex.org/F4320337534","funder_display_name":"National Institute on Minority Health and Health Disparities"},{"id":"https://openalex.org/G7549037155","display_name":"RCMI Infrastructure for Clinical and Translational Research (RCTR) (U54)","funder_award_id":"U54MD007588","funder_id":"https://openalex.org/F4320337534","funder_display_name":"National Institute on Minority Health and Health Disparities"},{"id":"https://openalex.org/G9000883586","display_name":"Center for Translational Research in Health Disparities","funder_award_id":"U54MD007602","funder_id":"https://openalex.org/F4320337534","funder_display_name":"National Institute on Minority Health and Health Disparities"}],"funders":[{"id":"https://openalex.org/F4320337338","display_name":"National Heart, Lung, and Blood Institute","ror":"https://ror.org/012pb6c26"},{"id":"https://openalex.org/F4320337348","display_name":"National Human Genome Research Institute","ror":"https://ror.org/00baak391"},{"id":"https://openalex.org/F4320337375","display_name":"National Center for Research Resources","ror":"https://ror.org/04pw6fb54"},{"id":"https://openalex.org/F4320337534","display_name":"National Institute on Minority Health and Health Disparities","ror":"https://ror.org/0493hgw16"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":31,"referenced_works":["https://openalex.org/W19189052","https://openalex.org/W1517631297","https://openalex.org/W1534058357","https://openalex.org/W1543005717","https://openalex.org/W1563715672","https://openalex.org/W1591325634","https://openalex.org/W1605079741","https://openalex.org/W1973376761","https://openalex.org/W1973601126","https://openalex.org/W1975935203","https://openalex.org/W1980884431","https://openalex.org/W1983116402","https://openalex.org/W1986365556","https://openalex.org/W1998700487","https://openalex.org/W2003343781","https://openalex.org/W2014374142","https://openalex.org/W2027270161","https://openalex.org/W2043108620","https://openalex.org/W2066491754","https://openalex.org/W2075186587","https://openalex.org/W2078080804","https://openalex.org/W2078593792","https://openalex.org/W2084643121","https://openalex.org/W2091106535","https://openalex.org/W2099273954","https://openalex.org/W2104304688","https://openalex.org/W2121406617","https://openalex.org/W2128622802","https://openalex.org/W2132696478","https://openalex.org/W2147072806","https://openalex.org/W2157241157"],"related_works":["https://openalex.org/W2055891505","https://openalex.org/W2022745948","https://openalex.org/W327380490","https://openalex.org/W2121607295","https://openalex.org/W4402635496","https://openalex.org/W2009993258","https://openalex.org/W2022385815","https://openalex.org/W4241257474","https://openalex.org/W2111466507","https://openalex.org/W2168243468"],"abstract_inverted_index":{"We":[0,34,55,74,114,151],"recently":[1],"discovered":[2,46],"a":[3,193,201,235],"dynamic":[4],"copy":[5],"number":[6],"variation":[7],"on":[8],"the":[9,36,40,52,82,86,104,108,124,129,133,140,143,147,154,210],"NCF1":[10,53,134,162],"(neutrophil":[11],"cytosolic":[12],"factor":[13],"1)":[14],"pseudogenes":[15,26,163,213,228],"in":[16,85,139,142,146,164,183,186,214,229],"human":[17,67,165,215,230],"populations.":[18],"In":[19],"this":[20,43],"study,":[21],"we":[22],"investigated":[23],"whether":[24],"these":[25,91,158,177],"are":[27,180,217],"functional":[28],"or":[29],"junk":[30],"as":[31,234],"described":[32],"before.":[33],"sequenced":[35],"RNAs":[37],"transcribed":[38,131],"from":[39,51,132],"genome":[41,216,231],"of":[42,157,161,196],"locus,":[44],"and":[45,63,89,126,199],"over":[47],"10":[48],"splicing":[49,58,100,159,178],"isoforms":[50,59,160],"pseudogenes.":[54],"cloned":[56],"4":[57],"into":[60,66],"expression":[61],"vectors":[62],"introduced":[64],"them":[65],"vascular":[68],"endothelial":[69],"cells":[70,87,125],"by":[71,167],"transient":[72,148],"transfection.":[73],"then":[75],"used":[76,115],"two":[77],"chemical":[78],"approaches":[79],"to":[80,122,190],"measure":[81],"superoxide":[83,105],"production":[84,106],"with":[88],"without":[90,220],"pseudogene":[92,99,135],"overexpression.":[93],"Our":[94,172],"data":[95,173],"showed":[96,174],"that":[97,128,175,212,226],"three":[98],"products":[101],"remarkably":[102],"reduced":[103],"after":[107],"GFP":[109],"(Green":[110],"fluorescent":[111],"protein)":[112],"normalization.":[113],"an":[116],"anti-HA":[117],"(Hemagglutinin":[118],"A)":[119],"tag":[120],"antibody":[121],"stain":[123],"confirmed":[127],"proteins":[130],"were":[136],"exclusively":[137],"localized":[138],"cytoplasm":[141],"perinuclear":[144],"area":[145],"transfection":[149],"assays.":[150],"further":[152],"examined":[153],"tissue":[155],"distribution":[156,203],"tissues":[166,185],"quantitative":[168],"real-time":[169],"PCR":[170],"analysis.":[171],"although":[176],"variants":[179],"ubiquitously":[181],"expressed":[182],"non-immune":[184],"human,":[187],"they":[188],"seem":[189],"be":[191],"under":[192],"tight":[194],"control":[195],"transcription":[197],"regulation":[198],"show":[200],"non-random":[202],"pattern":[204],"across":[205],"tissues.":[206],"This":[207],"study":[208],"challenges":[209],"concept":[211],"only":[218],"junks":[219],"biological":[221],"functions.":[222],"Moreover,":[223],"it":[224],"suggests":[225],"those":[227],"may":[232],"serve":[233],"natural":[236],"resource":[237],"for":[238],"novel":[239],"drug":[240],"discovery.":[241]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":2}],"updated_date":"2026-10-30T12:39:25.321706","created_date":"2016-06-24T00:00:00"}