{"id":"https://openalex.org/W150660268","doi":null,"title":"[In vitro activity of gallic acid against Candida albicans biofilms].","display_name":"[In vitro activity of gallic acid against Candida albicans biofilms].","publication_year":2009,"publication_date":"2009-05-01","ids":{"openalex":"https://openalex.org/W150660268","mag":"150660268","pmid":"https://pubmed.ncbi.nlm.nih.gov/19685753"},"language":"zh","primary_location":{"id":"pmid:19685753","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19685753","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5046311971","display_name":"Changzhong Wang","orcid":"https://orcid.org/0000-0002-4136-2433","observed_orcids":["https://orcid.org/0000-0002-4136-2433"]},"institutions":[{"id":"https://openalex.org/I253932293","display_name":"Anhui University of Traditional Chinese Medicine","ror":"https://ror.org/0139j4p80","country_code":"CN","type":"education","lineage":["https://openalex.org/I253932293"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Changzhong Wang","raw_affiliation_strings":["School of Integrated Traditional and Western Medicine, Anhui University of Traditional Chinese Medicine, Hefei 230038, China. ahwcz63@sina.com","School of Integrated Traditional and Western Medicine,Anhui University of Traditional Chinese Medicine, Hefei 230038, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Integrated Traditional and Western Medicine, Anhui University of Traditional Chinese Medicine, Hefei 230038, China. ahwcz63@sina.com","institution_ids":["https://openalex.org/I253932293"]},{"raw_affiliation_string":"School of Integrated Traditional and Western Medicine,Anhui University of Traditional Chinese Medicine, Hefei 230038, China","institution_ids":["https://openalex.org/I253932293"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5102638202","display_name":"Huijuan Cheng","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Huijuan Cheng","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081882565","display_name":"Yan Guan","orcid":"https://orcid.org/0000-0001-7653-5288","observed_orcids":["https://orcid.org/0000-0001-7653-5288"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yan Guan","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011048386","display_name":"Yan Wang","orcid":"https://orcid.org/0000-0002-8457-5287","observed_orcids":["https://orcid.org/0000-0002-8457-5287"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yan Wang","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5103082442","display_name":"Yun Yun","orcid":"https://orcid.org/0000-0002-1259-0541","observed_orcids":["https://orcid.org/0000-0002-1259-0541"]},"institutions":[{"id":"https://openalex.org/I253932293","display_name":"Anhui University of Traditional Chinese Medicine","ror":"https://ror.org/0139j4p80","country_code":"CN","type":"education","lineage":["https://openalex.org/I253932293"]}],"countries":["CN"],"is_corresponding":false,"raw_author_name":"Yun Yun","raw_affiliation_strings":["School of Integrated Traditional and Western Medicine,Anhui University of Traditional Chinese Medicine, Hefei 230038, China"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"School of Integrated Traditional and Western Medicine,Anhui University of Traditional Chinese Medicine, Hefei 230038, China","institution_ids":["https://openalex.org/I253932293"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.2301,"has_fulltext":false,"cited_by_count":12,"citation_normalized_percentile":{"value":0.58094197,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":96},"biblio":{"volume":"34","issue":"9","first_page":"1137","last_page":"40"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.9839000105857849,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10225","display_name":"Essential Oils and Antimicrobial Activity","score":0.008500000461935997,"subfield":{"id":"https://openalex.org/subfields/1106","display_name":"Food Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10593","display_name":"Bacterial biofilms and quorum sensing","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/gallic-acid","display_name":"gallic acid","score":1.0},{"id":"https://openalex.org/keywords/candida-albicans","display_name":"Candida albicans","score":0.9980000257492065},{"id":"https://openalex.org/keywords/biofilm","display_name":"biofilm","score":0.902999997138977},{"id":"https://openalex.org/keywords/antifungal-activity","display_name":"antifungal activity","score":0.953000009059906},{"id":"https://openalex.org/keywords/fungal-adhesion","display_name":"fungal adhesion","score":0.6259999871253967},{"id":"https://openalex.org/keywords/filamentous-growth","display_name":"filamentous growth","score":0.8640000224113464},{"id":"https://openalex.org/keywords/cytotoxicity","display_name":"cytotoxicity","score":0.8220000267028809},{"id":"https://openalex.org/keywords/minimum-inhibitory-concentration","display_name":"minimum inhibitory concentration","score":0.9110000133514404}],"concepts":[{"id":"https://openalex.org/C2778362808","wikidata":"https://www.wikidata.org/wiki/Q375837","display_name":"Gallic acid","level":3,"score":0.9912374019622803},{"id":"https://openalex.org/C2780917455","wikidata":"https://www.wikidata.org/wiki/Q310443","display_name":"Candida albicans","level":2,"score":0.8832799196243286},{"id":"https://openalex.org/C58123911","wikidata":"https://www.wikidata.org/wiki/Q467410","display_name":"Biofilm","level":3,"score":0.6884530782699585},{"id":"https://openalex.org/C145081991","wikidata":"https://www.wikidata.org/wiki/Q2576388","display_name":"Corpus albicans","level":3,"score":0.6296318173408508},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.6237220764160156},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5541175007820129},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.483595073223114},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2926531434059143},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.25102609395980835},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.20184257626533508},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.053927451372146606},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D002176","descriptor_name":"Candida albicans","qualifier_ui":"Q000166","qualifier_name":"cytology","is_major_topic":false},{"descriptor_ui":"D002176","descriptor_name":"Candida albicans","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D002176","descriptor_name":"Candida albicans","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D002448","descriptor_name":"Cell Adhesion","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005707","descriptor_name":"Gallic Acid","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D018441","descriptor_name":"Biofilms","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:19685753","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19685753","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica","raw_type":"Journal Article"},{"id":"mag:150660268","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19685753","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.8048999905586243}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2388840142","https://openalex.org/W2392355596","https://openalex.org/W2377602290","https://openalex.org/W2391035103","https://openalex.org/W15953300","https://openalex.org/W2612774870","https://openalex.org/W2361959530","https://openalex.org/W2366749939","https://openalex.org/W4390258453","https://openalex.org/W2120443316"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"investigate":[2],"the":[3,22,41,59,96,103],"effects":[4,61],"of":[5,24,43,48,62,68,91],"gallic":[6,25,44,63,69,92,110],"acid":[7,26,45,70,93,111],"against":[8,71,115],"Candida":[9],"albicans":[10,29,50,73,117],"biofilms":[11,30,74],"in":[12],"vitro.":[13],"METHOD:":[14],"XTT":[15],"reduction":[16],"assay":[17,54],"was":[18,37,55],"performed":[19],"to":[20,39,57],"determine":[21],"effect":[23,42],"on":[27,46],"C.":[28,49,72,116],"and":[31,34,52,86,99,102],"its":[32],"adherence,":[33],"microscopic":[35],"examination":[36],"conducted":[38],"assess":[40],"morphogenesis":[47],"biofilms;":[51],"cytotoxic":[53,107],"used":[56],"measure":[58],"adverse":[60],"acid.":[64],"RESULT:":[65],"SMIC50,":[66],"SMIC50":[67],"were":[75],"500,":[76],"1000":[77,87],"mg":[78,83,88],"x":[79,84,89],"L(-1),":[80],"respectively;":[81],"100":[82],"L(-1)":[85,90],"could":[94],"inhibit":[95],"initial":[97],"adherence":[98],"filamentous":[100],"growth,":[101],"agent":[104],"showed":[105],"poor":[106],"activity.":[108],"CONCLUSION:":[109],"displayed":[112],"potent":[113],"activity":[114],"biofilm.":[118]},"counts_by_year":[{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-02T09:45:03.842371","created_date":"2016-06-24T00:00:00"}