{"id":"https://openalex.org/W1506545824","doi":null,"title":"Characterising the role of the Cajal Body during a productive adenovirus infection","display_name":"Characterising the role of the Cajal Body during a productive adenovirus infection","publication_year":2012,"publication_date":"2012-12-01","ids":{"openalex":"https://openalex.org/W1506545824","mag":"1506545824"},"language":"en","primary_location":{"id":"pmh:oai:etheses.whiterose.ac.uk:4926","doi":null,"is_oa":false,"landing_page_url":"http://etheses.whiterose.ac.uk/4926/1/Laura%20White_thesis_2012.pdf","pdf_url":"http://etheses.whiterose.ac.uk/4926/1/Laura%20White_thesis_2012.pdf","source":{"id":"https://openalex.org/S4306401585","display_name":"White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2800616092","host_organization_name":"White Rose University Consortium","host_organization_lineage":["https://openalex.org/I2800616092"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"volume":null,"type":"dissertation","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://uilis.unsyiah.ac.id/opentheses/items/show/30532","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Laura White","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Laura White","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":true,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.7387999892234802,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10613","display_name":"Virus-based gene therapy research","score":0.7387999892234802,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.21250000596046448,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11841","display_name":"Nuclear Structure and Function","score":0.01360000018030405,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cajal-bodies","display_name":"Cajal bodies","score":0.9309999942779541},{"id":"https://openalex.org/keywords/coilin","display_name":"coilin","score":0.6959999799728394},{"id":"https://openalex.org/keywords/adenovirus-type-5","display_name":"adenovirus type 5","score":0.921999990940094},{"id":"https://openalex.org/keywords/late-gene-expression","display_name":"late gene expression","score":0.9610000252723694},{"id":"https://openalex.org/keywords/mrna-export","display_name":"mRNA export","score":0.8299999833106995},{"id":"https://openalex.org/keywords/alternative-splicing","display_name":"alternative splicing","score":0.7110000252723694},{"id":"https://openalex.org/keywords/early-gene-transcription","display_name":"early gene transcription","score":0.8600000143051147},{"id":"https://openalex.org/keywords/nuclear-compartments","display_name":"nuclear compartments","score":0.3330000042915344},{"id":"https://openalex.org/keywords/gene-therapy-vectors","display_name":"gene therapy vectors","score":0.699999988079071},{"id":"https://openalex.org/keywords/rnai-knockdown","display_name":"RNAi knockdown","score":0.6100000143051147},{"id":"https://openalex.org/keywords/a549-cells","display_name":"A549 cells","score":0.921999990940094},{"id":"https://openalex.org/keywords/immune-response-to-viral-vectors","display_name":"immune response to viral vectors","score":0.515999972820282},{"id":"https://openalex.org/keywords/nuclear-transport","display_name":"nuclear transport","score":0.5130000114440918},{"id":"https://openalex.org/keywords/nonstructural-proteins","display_name":"non-structural proteins","score":0.4690000116825104}],"concepts":[{"id":"https://openalex.org/C11922738","wikidata":"https://www.wikidata.org/wiki/Q3234345","display_name":"Cajal body","level":5,"score":0.909945011138916},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.7777689695358276},{"id":"https://openalex.org/C112952253","wikidata":"https://www.wikidata.org/wiki/Q14817956","display_name":"Nucleoplasm","level":4,"score":0.6853788495063782},{"id":"https://openalex.org/C166703698","wikidata":"https://www.wikidata.org/wiki/Q201993","display_name":"RNA interference","level":4,"score":0.5783025622367859},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5554545521736145},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.39377379417419434},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.32938140630722046},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2522023320198059},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2025168240070343},{"id":"https://openalex.org/C2780723820","wikidata":"https://www.wikidata.org/wiki/Q1934178","display_name":"Nucleus","level":2,"score":0.15671822428703308},{"id":"https://openalex.org/C183873130","wikidata":"https://www.wikidata.org/wiki/Q30869","display_name":"Nucleolus","level":3,"score":0.08450880646705627},{"id":"https://openalex.org/C54458228","wikidata":"https://www.wikidata.org/wiki/Q237218","display_name":"RNA splicing","level":4,"score":0.0}],"mesh":[],"locations_count":3,"locations":[{"id":"pmh:oai:etheses.whiterose.ac.uk:4926","doi":null,"is_oa":false,"landing_page_url":"http://etheses.whiterose.ac.uk/4926/1/Laura%20White_thesis_2012.pdf","pdf_url":"http://etheses.whiterose.ac.uk/4926/1/Laura%20White_thesis_2012.pdf","source":{"id":"https://openalex.org/S4306401585","display_name":"White Rose eTheses Online (University of Leeds, The University of Sheffield, University of York)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2800616092","host_organization_name":"White Rose University Consortium","host_organization_lineage":["https://openalex.org/I2800616092"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"pmh:oai:uilis.unsyiah.ac.id:30532","doi":null,"is_oa":true,"landing_page_url":"http://uilis.unsyiah.ac.id/opentheses/items/show/30532","pdf_url":"http://uilis.unsyiah.ac.id/opentheses/items/show/30532","source":{"id":"https://openalex.org/S4377196378","display_name":"UPT. Syiah Kuala University Library (Syiah Kuala University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I187494767","host_organization_name":"Universitas Syiah Kuala","host_organization_lineage":["https://openalex.org/I187494767"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},{"id":"mag:1506545824","doi":null,"is_oa":false,"landing_page_url":"https://etheses.whiterose.ac.uk/4926/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:uilis.unsyiah.ac.id:30532","doi":null,"is_oa":true,"landing_page_url":"http://uilis.unsyiah.ac.id/opentheses/items/show/30532","pdf_url":"http://uilis.unsyiah.ac.id/opentheses/items/show/30532","source":{"id":"https://openalex.org/S4377196378","display_name":"UPT. Syiah Kuala University Library (Syiah Kuala University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I187494767","host_organization_name":"Universitas Syiah Kuala","host_organization_lineage":["https://openalex.org/I187494767"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Thesis"},"sustainable_development_goals":[{"score":0.8048999905586243,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1506545824.pdf","grobid_xml":"https://content.openalex.org/works/W1506545824.grobid-xml"},"referenced_works_count":840,"referenced_works":["https://openalex.org/W9260168","https://openalex.org/W58625194","https://openalex.org/W64861853","https://openalex.org/W81266651","https://openalex.org/W132916961","https://openalex.org/W155422586","https://openalex.org/W161101904","https://openalex.org/W178813549","https://openalex.org/W339058748","https://openalex.org/W1271675486","https://openalex.org/W1484339355","https://openalex.org/W1486052360","https://openalex.org/W1489610462","https://openalex.org/W1491769950","https://openalex.org/W1494490000","https://openalex.org/W1496981472","https://openalex.org/W1498027707","https://openalex.org/W1502617758","https://openalex.org/W1503270919","https://openalex.org/W1504558880","https://openalex.org/W1507619429","https://openalex.org/W1512653355","https://openalex.org/W1521240136","https://openalex.org/W1522200518","https://openalex.org/W1525353688","https://openalex.org/W1525926169","https://openalex.org/W1527444689","https://openalex.org/W1528256607","https://openalex.org/W1529048149","https://openalex.org/W1531644439","https://openalex.org/W1532197406","https://openalex.org/W1532984977","https://openalex.org/W1537558609","https://openalex.org/W1543500873","https://openalex.org/W1545138955","https://openalex.org/W1556770656","https://openalex.org/W1560526335","https://openalex.org/W1563246884","https://openalex.org/W1563488686","https://openalex.org/W1564846515","https://openalex.org/W1571644961","https://openalex.org/W1572160541","https://openalex.org/W1575071140","https://openalex.org/W1576538493","https://openalex.org/W1578747168","https://openalex.org/W1579420753","https://openalex.org/W1582164157","https://openalex.org/W1584231747","https://openalex.org/W1594317926","https://openalex.org/W1597577233","https://openalex.org/W1599342426","https://openalex.org/W1602450046","https://openalex.org/W1602517735","https://openalex.org/W1603052159","https://openalex.org/W1605241030","https://openalex.org/W1611419331","https://openalex.org/W1635552303","https://openalex.org/W1635667563","https://openalex.org/W1651086125","https://openalex.org/W1655574943","https://openalex.org/W1665866727","https://openalex.org/W1734478427","https://openalex.org/W1765650288","https://openalex.org/W1778470944","https://openalex.org/W1779510623","https://openalex.org/W1816486083","https://openalex.org/W1834610545","https://openalex.org/W1838672790","https://openalex.org/W1849971351","https://openalex.org/W1857356080","https://openalex.org/W1877406376","https://openalex.org/W1879996757","https://openalex.org/W1886007601","https://openalex.org/W1896158532","https://openalex.org/W1904553979","https://openalex.org/W1910404793","https://openalex.org/W1918714789","https://openalex.org/W1919331395","https://openalex.org/W1921267352","https://openalex.org/W1922329782","https://openalex.org/W1925567582","https://openalex.org/W1926037744","https://openalex.org/W1927581912","https://openalex.org/W1940378630","https://openalex.org/W1940539890","https://openalex.org/W1942379865","https://openalex.org/W1950423469","https://openalex.org/W1961949089","https://openalex.org/W1963838671","https://openalex.org/W1964629933","https://openalex.org/W1964644257","https://openalex.org/W1964897439","https://openalex.org/W1965013083","https://openalex.org/W1965388358","https://openalex.org/W1965851786","https://openalex.org/W1966037150","https://openalex.org/W1966063731","https://openalex.org/W1966193677","https://openalex.org/W1966732201","https://openalex.org/W1966735041","https://openalex.org/W1967033604","https://openalex.org/W1967439927","https://openalex.org/W1967969338","https://openalex.org/W1968444850","https://openalex.org/W1968697793","https://openalex.org/W1969131246","https://openalex.org/W1969445083","https://openalex.org/W1969585647","https://openalex.org/W1969708945","https://openalex.org/W1970042886","https://openalex.org/W1970061483","https://openalex.org/W1970234384","https://openalex.org/W1970867680","https://openalex.org/W1970977612","https://openalex.org/W1971022093","https://openalex.org/W1971385603","https://openalex.org/W1971765707","https://openalex.org/W1972378799","https://openalex.org/W1972440264","https://openalex.org/W1972620825","https://openalex.org/W1973106610","https://openalex.org/W1973158635","https://openalex.org/W1973218522","https://openalex.org/W1973637021","https://openalex.org/W1974556701","https://openalex.org/W1975408822","https://openalex.org/W1975994504","https://openalex.org/W1976144441","https://openalex.org/W1976244139","https://openalex.org/W1976732528","https://openalex.org/W1976870459","https://openalex.org/W1977254598","https://openalex.org/W1977618491","https://openalex.org/W1977964349","https://openalex.org/W1978033434","https://openalex.org/W1978306626","https://openalex.org/W1978461534","https://openalex.org/W1978728124","https://openalex.org/W1978967539","https://openalex.org/W1979289925","https://openalex.org/W1979399955","https://openalex.org/W1979520474","https://openalex.org/W1979772572","https://openalex.org/W1979838224","https://openalex.org/W1979961380","https://openalex.org/W1980408287","https://openalex.org/W1980477780","https://openalex.org/W1980663819","https://openalex.org/W1981069374","https://openalex.org/W1981176424","https://openalex.org/W1981327173","https://openalex.org/W1982447331","https://openalex.org/W1983673827","https://openalex.org/W1983811755","https://openalex.org/W1983860672","https://openalex.org/W1984143549","https://openalex.org/W1984618049","https://openalex.org/W1984878810","https://openalex.org/W1984912806","https://openalex.org/W1985135583","https://openalex.org/W1985151525","https://openalex.org/W1985581648","https://openalex.org/W1985717866","https://openalex.org/W1986026506","https://openalex.org/W1986406001","https://openalex.org/W1986945946","https://openalex.org/W1987530472","https://openalex.org/W1987975025","https://openalex.org/W1988049768","https://openalex.org/W1988146888","https://openalex.org/W1988399759","https://openalex.org/W1988570973","https://openalex.org/W1988960910","https://openalex.org/W1989158987","https://openalex.org/W1989725253","https://openalex.org/W1989736208","https://openalex.org/W1991377750","https://openalex.org/W1991641998","https://openalex.org/W1991723154","https://openalex.org/W1991772727","https://openalex.org/W1991934695","https://openalex.org/W1992200158","https://openalex.org/W1992436314","https://openalex.org/W1992605446","https://openalex.org/W1993062465","https://openalex.org/W1993519463","https://openalex.org/W1993570130","https://openalex.org/W1993838942","https://openalex.org/W1994532304","https://openalex.org/W1994711663","https://openalex.org/W1994725538","https://openalex.org/W1995029167","https://openalex.org/W1995178146","https://openalex.org/W1995276829","https://openalex.org/W1995350396","https://openalex.org/W1995496004","https://openalex.org/W1995540345","https://openalex.org/W1995842607","https://openalex.org/W1995948096","https://openalex.org/W1996063915","https://openalex.org/W1996412713","https://openalex.org/W1997493439","https://openalex.org/W1997659110","https://openalex.org/W1998291975","https://openalex.org/W1998314264","https://openalex.org/W1998335196","https://openalex.org/W1998697301","https://openalex.org/W1999064296","https://openalex.org/W1999440327","https://openalex.org/W1999469221","https://openalex.org/W1999614623","https://openalex.org/W1999622475","https://openalex.org/W1999876280","https://openalex.org/W1999962568","https://openalex.org/W2000752368","https://openalex.org/W2000939182","https://openalex.org/W2000971601","https://openalex.org/W2001006317","https://openalex.org/W2001092165","https://openalex.org/W2001758369","https://openalex.org/W2002033363","https://openalex.org/W2002112358","https://openalex.org/W2002373110","https://openalex.org/W2002969314","https://openalex.org/W2003411878","https://openalex.org/W2003560611","https://openalex.org/W2003686155","https://openalex.org/W2004103813","https://openalex.org/W2005123048","https://openalex.org/W2005363422","https://openalex.org/W2005447120","https://openalex.org/W2005490545","https://openalex.org/W2005664674","https://openalex.org/W2006048118","https://openalex.org/W2006931677","https://openalex.org/W2007812895","https://openalex.org/W2008430410","https://openalex.org/W2008694035","https://openalex.org/W2008927436","https://openalex.org/W2009125409","https://openalex.org/W2009193892","https://openalex.org/W2009289802","https://openalex.org/W2009510163","https://openalex.org/W2010605653","https://openalex.org/W2010666698","https://openalex.org/W2011282013","https://openalex.org/W2011762615","https://openalex.org/W2012401859","https://openalex.org/W2012714016","https://openalex.org/W2012734297","https://openalex.org/W2013043484","https://openalex.org/W2013467101","https://openalex.org/W2013766398","https://openalex.org/W2013815517","https://openalex.org/W2014414194","https://openalex.org/W2014517533","https://openalex.org/W2014672146","https://openalex.org/W2016080258","https://openalex.org/W2016200465","https://openalex.org/W2016385127","https://openalex.org/W2016832835","https://openalex.org/W2017302876","https://openalex.org/W2017441541","https://openalex.org/W2017576006","https://openalex.org/W2017726973","https://openalex.org/W2017743336","https://openalex.org/W2018120875","https://openalex.org/W2018551927","https://openalex.org/W2018611026","https://openalex.org/W2019414781","https://openalex.org/W2019458198","https://openalex.org/W2019475067","https://openalex.org/W2019731882","https://openalex.org/W2019845267","https://openalex.org/W2019874614","https://openalex.org/W2020204531","https://openalex.org/W2020422048","https://openalex.org/W2021236605","https://openalex.org/W2021819115","https://openalex.org/W2021999304","https://openalex.org/W2022523272","https://openalex.org/W2022681782","https://openalex.org/W2023436568","https://openalex.org/W2023546332","https://openalex.org/W2023930134","https://openalex.org/W2024125295","https://openalex.org/W2024388361","https://openalex.org/W2024839121","https://openalex.org/W2024968679","https://openalex.org/W2025823298","https://openalex.org/W2025934694","https://openalex.org/W2026180423","https://openalex.org/W2026677489","https://openalex.org/W2026856852","https://openalex.org/W2026885676","https://openalex.org/W2027085235","https://openalex.org/W2027339548","https://openalex.org/W2027361460","https://openalex.org/W2027372593","https://openalex.org/W2027727579","https://openalex.org/W2027874507","https://openalex.org/W2027980197","https://openalex.org/W2028363713","https://openalex.org/W2028794785","https://openalex.org/W2028903990","https://openalex.org/W2029784758","https://openalex.org/W2030004974","https://openalex.org/W2030201014","https://openalex.org/W2030375968","https://openalex.org/W2030976397","https://openalex.org/W2031375145","https://openalex.org/W2031414445","https://openalex.org/W2031922297","https://openalex.org/W2032396826","https://openalex.org/W2032437024","https://openalex.org/W2032464841","https://openalex.org/W2033572206","https://openalex.org/W2034041872","https://openalex.org/W2034116174","https://openalex.org/W2034201039","https://openalex.org/W2034277114","https://openalex.org/W2034289420","https://openalex.org/W2034516968","https://openalex.org/W2034684223","https://openalex.org/W2034890220","https://openalex.org/W2034902271","https://openalex.org/W2035229948","https://openalex.org/W2035380422","https://openalex.org/W2035633778","https://openalex.org/W2035659472","https://openalex.org/W2035755400","https://openalex.org/W2035834158","https://openalex.org/W2037091922","https://openalex.org/W2037818544","https://openalex.org/W2038746284","https://openalex.org/W2039165252","https://openalex.org/W2039394152","https://openalex.org/W2039531548","https://openalex.org/W2039945618","https://openalex.org/W2040081179","https://openalex.org/W2040276875","https://openalex.org/W2040539493","https://openalex.org/W2040905755","https://openalex.org/W2041151229","https://openalex.org/W2041329507","https://openalex.org/W2041914999","https://openalex.org/W2042024842","https://openalex.org/W2042712894","https://openalex.org/W2042824670","https://openalex.org/W2042943782","https://openalex.org/W2043327482","https://openalex.org/W2043348864","https://openalex.org/W2043368790","https://openalex.org/W2043801356","https://openalex.org/W2044146927","https://openalex.org/W2044338251","https://openalex.org/W2045845081","https://openalex.org/W2046037983","https://openalex.org/W2046385082","https://openalex.org/W2046736654","https://openalex.org/W2047285578","https://openalex.org/W2047555090","https://openalex.org/W2047666280","https://openalex.org/W2048167369","https://openalex.org/W2048442183","https://openalex.org/W2049060720","https://openalex.org/W2049379969","https://openalex.org/W2049652011","https://openalex.org/W2049779694","https://openalex.org/W2050621375","https://openalex.org/W2050867140","https://openalex.org/W2051037608","https://openalex.org/W2051282896","https://openalex.org/W2051758487","https://openalex.org/W2051776908","https://openalex.org/W2053035745","https://openalex.org/W2053037116","https://openalex.org/W2053147978","https://openalex.org/W2053516485","https://openalex.org/W2053606615","https://openalex.org/W2053647514","https://openalex.org/W2053783765","https://openalex.org/W2053881125","https://openalex.org/W2054408541","https://openalex.org/W2054519549","https://openalex.org/W2054950387","https://openalex.org/W2055162988","https://openalex.org/W2055339678","https://openalex.org/W2055490337","https://openalex.org/W2056216914","https://openalex.org/W2056680264","https://openalex.org/W2057049809","https://openalex.org/W2057628471","https://openalex.org/W2057741968","https://openalex.org/W2058796068","https://openalex.org/W2058886425","https://openalex.org/W2058970225","https://openalex.org/W2059007379","https://openalex.org/W2059296004","https://openalex.org/W2059981828","https://openalex.org/W2060608189","https://openalex.org/W2060643446","https://openalex.org/W2060817283","https://openalex.org/W2060908886","https://openalex.org/W2061642491","https://openalex.org/W2061803918","https://openalex.org/W2061914660","https://openalex.org/W2062379285","https://openalex.org/W2062855335","https://openalex.org/W2063083122","https://openalex.org/W2063822655","https://openalex.org/W2064842780","https://openalex.org/W2065018936","https://openalex.org/W2065466457","https://openalex.org/W2065530211","https://openalex.org/W2065656557","https://openalex.org/W2065777975","https://openalex.org/W2065904022","https://openalex.org/W2066438071","https://openalex.org/W2066835429","https://openalex.org/W2067000269","https://openalex.org/W2067047912","https://openalex.org/W2067382966","https://openalex.org/W2067493684","https://openalex.org/W2067547076","https://openalex.org/W2067780078","https://openalex.org/W2068030181","https://openalex.org/W2068403110","https://openalex.org/W2068796966","https://openalex.org/W2069097579","https://openalex.org/W2069332834","https://openalex.org/W2070126991","https://openalex.org/W2070498223","https://openalex.org/W2070877870","https://openalex.org/W2071528841","https://openalex.org/W2071907263","https://openalex.org/W2072759188","https://openalex.org/W2072798319","https://openalex.org/W2073491051","https://openalex.org/W2074097219","https://openalex.org/W2074288699","https://openalex.org/W2075020213","https://openalex.org/W2075521423","https://openalex.org/W2075977300","https://openalex.org/W2076060547","https://openalex.org/W2076142853","https://openalex.org/W2076414137","https://openalex.org/W2077154575","https://openalex.org/W2077600107","https://openalex.org/W2077609327","https://openalex.org/W2078145793","https://openalex.org/W2078655896","https://openalex.org/W2079156263","https://openalex.org/W2079233637","https://openalex.org/W2079378073","https://openalex.org/W2079520949","https://openalex.org/W2079815614","https://openalex.org/W2079963781","https://openalex.org/W2080011616","https://openalex.org/W2080030488","https://openalex.org/W2080110672","https://openalex.org/W2080421046","https://openalex.org/W2080706214","https://openalex.org/W2080767553","https://openalex.org/W2082223338","https://openalex.org/W2082462474","https://openalex.org/W2082707643","https://openalex.org/W2082823773","https://openalex.org/W2082843075","https://openalex.org/W2083009248","https://openalex.org/W2083423683","https://openalex.org/W2084471200","https://openalex.org/W2084772469","https://openalex.org/W2085176501","https://openalex.org/W2085206569","https://openalex.org/W2085388950","https://openalex.org/W2085465310","https://openalex.org/W2085492596","https://openalex.org/W2085628838","https://openalex.org/W2087287669","https://openalex.org/W2087510109","https://openalex.org/W2087677968","https://openalex.org/W2087718509","https://openalex.org/W2087789491","https://openalex.org/W2088091691","https://openalex.org/W2089779180","https://openalex.org/W2090257555","https://openalex.org/W2091077559","https://openalex.org/W2091204895","https://openalex.org/W2091345758","https://openalex.org/W2091620613","https://openalex.org/W2091955128","https://openalex.org/W2092216600","https://openalex.org/W2092940521","https://openalex.org/W2093120959","https://openalex.org/W2093139273","https://openalex.org/W2093230613","https://openalex.org/W2093362562","https://openalex.org/W2093424805","https://openalex.org/W2093646238","https://openalex.org/W2093979243","https://openalex.org/W2094212271","https://openalex.org/W2094246972","https://openalex.org/W2094376975","https://openalex.org/W2094401820","https://openalex.org/W2095292274","https://openalex.org/W2095736730","https://openalex.org/W2096018896","https://openalex.org/W2096546138","https://openalex.org/W2096650232","https://openalex.org/W2096768964","https://openalex.org/W2097627784","https://openalex.org/W2097699811","https://openalex.org/W2098059646","https://openalex.org/W2098158408","https://openalex.org/W2098302168","https://openalex.org/W2098472306","https://openalex.org/W2098601756","https://openalex.org/W2098974921","https://openalex.org/W2099287214","https://openalex.org/W2099338303","https://openalex.org/W2099803230","https://openalex.org/W2100099919","https://openalex.org/W2100262544","https://openalex.org/W2100324752","https://openalex.org/W2100556118","https://openalex.org/W2100812409","https://openalex.org/W2101519160","https://openalex.org/W2101543197","https://openalex.org/W2101871282","https://openalex.org/W2101956311","https://openalex.org/W2102152121","https://openalex.org/W2102621085","https://openalex.org/W2102838769","https://openalex.org/W2102938475","https://openalex.org/W2102999073","https://openalex.org/W2103015533","https://openalex.org/W2103187359","https://openalex.org/W2103250022","https://openalex.org/W2103504827","https://openalex.org/W2104289479","https://openalex.org/W2104504930","https://openalex.org/W2104618420","https://openalex.org/W2105234784","https://openalex.org/W2105375220","https://openalex.org/W2105495356","https://openalex.org/W2106254834","https://openalex.org/W2106294990","https://openalex.org/W2106476684","https://openalex.org/W2106579890","https://openalex.org/W2106601695","https://openalex.org/W2106618433","https://openalex.org/W2106830069","https://openalex.org/W2107195089","https://openalex.org/W2107244138","https://openalex.org/W2107731897","https://openalex.org/W2107864263","https://openalex.org/W2107925055","https://openalex.org/W2108018047","https://openalex.org/W2108075874","https://openalex.org/W2108482850","https://openalex.org/W2108704467","https://openalex.org/W2108959187","https://openalex.org/W2109055236","https://openalex.org/W2109406098","https://openalex.org/W2109552144","https://openalex.org/W2109831945","https://openalex.org/W2109890939","https://openalex.org/W2110063564","https://openalex.org/W2110241873","https://openalex.org/W2110544738","https://openalex.org/W2110856519","https://openalex.org/W2110875913","https://openalex.org/W2110989535","https://openalex.org/W2111072547","https://openalex.org/W2111496511","https://openalex.org/W2111575876","https://openalex.org/W2111688179","https://openalex.org/W2111754083","https://openalex.org/W2112201931","https://openalex.org/W2112402028","https://openalex.org/W2112441546","https://openalex.org/W2113471433","https://openalex.org/W2113768195","https://openalex.org/W2114129635","https://openalex.org/W2114692906","https://openalex.org/W2114824706","https://openalex.org/W2115133270","https://openalex.org/W2115445026","https://openalex.org/W2115445757","https://openalex.org/W2115499978","https://openalex.org/W2115597318","https://openalex.org/W2115625096","https://openalex.org/W2115718997","https://openalex.org/W2115733534","https://openalex.org/W2115972488","https://openalex.org/W2116071714","https://openalex.org/W2116167672","https://openalex.org/W2116175479","https://openalex.org/W2116302199","https://openalex.org/W2116359481","https://openalex.org/W2116899012","https://openalex.org/W2116932998","https://openalex.org/W2117383597","https://openalex.org/W2117403816","https://openalex.org/W2117568376","https://openalex.org/W2117838192","https://openalex.org/W2117996979","https://openalex.org/W2118183757","https://openalex.org/W2118483219","https://openalex.org/W2118485393","https://openalex.org/W2118511790","https://openalex.org/W2118656013","https://openalex.org/W2119241406","https://openalex.org/W2119629835","https://openalex.org/W2119990616","https://openalex.org/W2120190354","https://openalex.org/W2121037023","https://openalex.org/W2121183277","https://openalex.org/W2121261969","https://openalex.org/W2121834970","https://openalex.org/W2122033091","https://openalex.org/W2122289183","https://openalex.org/W2122308980","https://openalex.org/W2122342818","https://openalex.org/W2123005075","https://openalex.org/W2123019823","https://openalex.org/W2123449896","https://openalex.org/W2123721271","https://openalex.org/W2124469032","https://openalex.org/W2124502040","https://openalex.org/W2124614845","https://openalex.org/W2124715146","https://openalex.org/W2124815451","https://openalex.org/W2125214575","https://openalex.org/W2125373492","https://openalex.org/W2125809370","https://openalex.org/W2126294946","https://openalex.org/W2126556619","https://openalex.org/W2126730534","https://openalex.org/W2126848848","https://openalex.org/W2127090048","https://openalex.org/W2127593856","https://openalex.org/W2127707170","https://openalex.org/W2128366838","https://openalex.org/W2128787099","https://openalex.org/W2129136044","https://openalex.org/W2129333552","https://openalex.org/W2129464214","https://openalex.org/W2129566110","https://openalex.org/W2129609211","https://openalex.org/W2130076705","https://openalex.org/W2130657959","https://openalex.org/W2130685017","https://openalex.org/W2130892718","https://openalex.org/W2131233598","https://openalex.org/W2131245700","https://openalex.org/W2131445177","https://openalex.org/W2131517280","https://openalex.org/W2132300826","https://openalex.org/W2132759801","https://openalex.org/W2133342796","https://openalex.org/W2134275666","https://openalex.org/W2134738317","https://openalex.org/W2134997389","https://openalex.org/W2135076356","https://openalex.org/W2135080095","https://openalex.org/W2135087521","https://openalex.org/W2135241378","https://openalex.org/W2135471102","https://openalex.org/W2135493103","https://openalex.org/W2136273864","https://openalex.org/W2136686995","https://openalex.org/W2136849872","https://openalex.org/W2137283204","https://openalex.org/W2137681938","https://openalex.org/W2137867170","https://openalex.org/W2138110425","https://openalex.org/W2138165292","https://openalex.org/W2138204634","https://openalex.org/W2138364237","https://openalex.org/W2138397691","https://openalex.org/W2138657329","https://openalex.org/W2139168442","https://openalex.org/W2139507233","https://openalex.org/W2139631855","https://openalex.org/W2139746879","https://openalex.org/W2140186583","https://openalex.org/W2140468862","https://openalex.org/W2140536809","https://openalex.org/W2140553495","https://openalex.org/W2140576339","https://openalex.org/W2140643621","https://openalex.org/W2140791473","https://openalex.org/W2140896857","https://openalex.org/W2140927361","https://openalex.org/W2140995557","https://openalex.org/W2141262351","https://openalex.org/W2141475323","https://openalex.org/W2141610087","https://openalex.org/W2142122497","https://openalex.org/W2142299476","https://openalex.org/W2142519388","https://openalex.org/W2142648346","https://openalex.org/W2142707328","https://openalex.org/W2142732844","https://openalex.org/W2143079500","https://openalex.org/W2143146123","https://openalex.org/W2143350291","https://openalex.org/W2143356450","https://openalex.org/W2143408261","https://openalex.org/W2143567623","https://openalex.org/W2144144425","https://openalex.org/W2145237465","https://openalex.org/W2145292103","https://openalex.org/W2145479669","https://openalex.org/W2145678829","https://openalex.org/W2146377171","https://openalex.org/W2146404878","https://openalex.org/W2146589802","https://openalex.org/W2146870828","https://openalex.org/W2147195316","https://openalex.org/W2147515018","https://openalex.org/W2147613443","https://openalex.org/W2147767880","https://openalex.org/W2147896158","https://openalex.org/W2147973149","https://openalex.org/W2148597965","https://openalex.org/W2148750580","https://openalex.org/W2148838665","https://openalex.org/W2148954829","https://openalex.org/W2149062070","https://openalex.org/W2149139293","https://openalex.org/W2149299119","https://openalex.org/W2149863495","https://openalex.org/W2150344629","https://openalex.org/W2150364154","https://openalex.org/W2150409766","https://openalex.org/W2150728394","https://openalex.org/W2150995202","https://openalex.org/W2152156251","https://openalex.org/W2152348733","https://openalex.org/W2152419816","https://openalex.org/W2152442213","https://openalex.org/W2152470748","https://openalex.org/W2152807182","https://openalex.org/W2153150264","https://openalex.org/W2153161471","https://openalex.org/W2153176195","https://openalex.org/W2153231414","https://openalex.org/W2153542488","https://openalex.org/W2153710947","https://openalex.org/W2153790089","https://openalex.org/W2155375498","https://openalex.org/W2155705991","https://openalex.org/W2155781667","https://openalex.org/W2156150950","https://openalex.org/W2156452197","https://openalex.org/W2156786214","https://openalex.org/W2157642353","https://openalex.org/W2158529979","https://openalex.org/W2158857731","https://openalex.org/W2158990839","https://openalex.org/W2159081113","https://openalex.org/W2159601181","https://openalex.org/W2159829912","https://openalex.org/W2160265494","https://openalex.org/W2160276168","https://openalex.org/W2160575460","https://openalex.org/W2160683304","https://openalex.org/W2160872319","https://openalex.org/W2161902637","https://openalex.org/W2162450109","https://openalex.org/W2162530599","https://openalex.org/W2162620374","https://openalex.org/W2162648910","https://openalex.org/W2162692975","https://openalex.org/W2162897963","https://openalex.org/W2163010298","https://openalex.org/W2163643581","https://openalex.org/W2163669373","https://openalex.org/W2163793886","https://openalex.org/W2163887454","https://openalex.org/W2164269732","https://openalex.org/W2164294989","https://openalex.org/W2164440528","https://openalex.org/W2164458996","https://openalex.org/W2164609914","https://openalex.org/W2164880484","https://openalex.org/W2165131038","https://openalex.org/W2165226718","https://openalex.org/W2165532730","https://openalex.org/W2165896601","https://openalex.org/W2166002553","https://openalex.org/W2166043441","https://openalex.org/W2166842178","https://openalex.org/W2166885155","https://openalex.org/W2167299010","https://openalex.org/W2167331686","https://openalex.org/W2167570765","https://openalex.org/W2167786336","https://openalex.org/W2167939720","https://openalex.org/W2168652503","https://openalex.org/W2168879519","https://openalex.org/W2168971544","https://openalex.org/W2169864486","https://openalex.org/W2170299265","https://openalex.org/W2170325846","https://openalex.org/W2170645981","https://openalex.org/W2170736126","https://openalex.org/W2170753410","https://openalex.org/W2170819844","https://openalex.org/W2170886452","https://openalex.org/W2171029513","https://openalex.org/W2171168707","https://openalex.org/W2171258458","https://openalex.org/W2171304774","https://openalex.org/W2171449127","https://openalex.org/W2171477438","https://openalex.org/W2171578468","https://openalex.org/W2248056767","https://openalex.org/W2249729856","https://openalex.org/W2262829041","https://openalex.org/W2275191855","https://openalex.org/W2280340122","https://openalex.org/W2290524938","https://openalex.org/W2313254115","https://openalex.org/W2316543256","https://openalex.org/W2326787949","https://openalex.org/W2334093679","https://openalex.org/W2346539064","https://openalex.org/W2349905826","https://openalex.org/W2398896370","https://openalex.org/W2401051457","https://openalex.org/W2407046590","https://openalex.org/W2414660779","https://openalex.org/W2429124956","https://openalex.org/W2437085630","https://openalex.org/W3216705818","https://openalex.org/W7100382521"],"related_works":["https://openalex.org/W4387357218","https://openalex.org/W1979520474","https://openalex.org/W7166612531","https://openalex.org/W2051455566","https://openalex.org/W2079233637","https://openalex.org/W2019152000","https://openalex.org/W2102651248","https://openalex.org/W2053516485","https://openalex.org/W7096979205","https://openalex.org/W2026885676"],"abstract_inverted_index":{"Human":[0],"adenoviruses":[1],"(Ads)":[2],"are":[3],"DNA":[4],"viruses":[5,398],"believed":[6],"to":[7,96,127,144,269,281,308,369,406,434],"hold":[8],"potential":[9],"as":[10,70],"gene":[11,44,311],"therapy":[12],"vectors.":[13],"However,":[14,108,278],"Ad":[15,42,104,115,138,212,216,233,241,250,265,293,319,329,349,377,447],"vectors":[16],"often":[17],"express":[18],"residual":[19],"late":[20,43,50,105,116,237],"structural":[21],"proteins,":[22,295],"which":[23],"stimulate":[24],"immune":[25],"responses":[26],"resulting":[27],"in":[28,66,100,114,196,254,264,279,286,289,328,343,361,376,387,410,425,441],"rapid":[29],"clearance":[30],"of":[31,38,52,90,103,112,123,131,148,155,171,186,222,232,249,292,318,339,374,382,427,439],"the":[32,39,49,71,87,101,109,129,146,180,184,209,225,230,275,290,337,353,371,416,436],"vector.":[33],"Therefore":[34],"a":[35,62,98,262,326,357,383,408],"greater":[36],"understanding":[37],"mechanisms":[40],"controlling":[41],"expression":[45,102,118,243],"is":[46,75,119,352,366,399,415,432],"required.":[47],"During":[48],"phase":[51,106,238],"adenovirus":[53],"5":[54],"(Ad5)":[55],"infection":[56,154,395,448,451],"it":[57],"was":[58,94,126,142,160,175,194,244,252,306,404],"previously":[59],"shown":[60],"that":[61,259,323,420],"nuclear":[63,247],"compartment":[64],"involved":[65,424],"RNA":[67,200],"metabolism":[68],"known":[69,405],"Cajal":[72],"body":[73],"(CB)":[74],"disassembled":[76],"from":[77,162,177],"1-6":[78],"punctate":[79],"domains":[80],"per":[81],"cell":[82],"into":[83,164,179],"numerous":[84],"microfoci.":[85],"Furthermore,":[86,380],"marker":[88],"protein":[89,117],"CBs,":[91],"p80":[92],"coilin,":[93,270,282],"suggested":[95,322],"play":[97,407],"role":[99,263,327,358,384,409],"proteins.":[107,239],"exact":[110,372],"function":[111,373,438],"coilin":[113,132,159,187,193,223,260,375,386],"unknown.":[120],"The":[121],"aim":[122],"this":[124,414],"investigation":[125,335,381],"determine":[128],"roles":[130,185,347],"and":[133,188,208,215,228,236,313,331,391,443,449],"additional":[134],"CB":[135,150,167,341],"proteins":[136,151,213,298,342],"during":[137,190,348,394,446,450],"infection.":[139,350],"\\nImmunofluorescence":[140],"microscopy":[141],"utilised":[143],"investigate":[145],"redistribution":[147],"key":[149],"following":[152],"Ad5":[153,191,207],"A549":[156,197],"cells.":[157,256],"Whilst":[158],"redistributed":[161,176],"CBs":[163,178,360],"microfoci,":[165],"another":[166],"protein,":[168],"termed":[169],"survival":[170],"motor":[172],"neuron":[173],"(SMN),":[174],"nucleoplasm.":[181],"To":[182],"assess":[183],"SMN":[189,271,283,304,324,403,421,440],"infection,":[192],"depleted":[195],"cells":[198],"by":[199],"interference":[201],"(RNAi).":[202],"Cells":[203],"were":[204,219,299],"infected":[205],"with":[206,396,452],"virus":[210,226,276,428,454],"yield,":[211],"levels":[214,218,291],"mRNA":[217,242,266,332,362,378,389,392,412,444],"assessed.":[220],"Depletion":[221],"reduced":[224,274],"yield":[227],"decreased":[229],"synthesis":[231],"early,":[234],"intermediate":[235],"Although":[240,402],"mostly":[245],"unaffected,":[246],"export":[248,390,393],"mRNAs":[251],"abrogated":[253],"coilin-depleted":[255],"This":[257,321,351],"indicated":[258],"plays":[261,325],"transport.":[267],"Similar":[268],"depletion":[272,284,305],"significantly":[273],"yield.":[277],"contrast":[280],"resulted":[285],"significant":[287],"decreases":[288],"capsid":[294],"whilst":[296],"non-structural":[297],"either":[300],"increased":[301],"or":[302],"unaffected.":[303],"found":[307],"reduce":[309],"early":[310],"transcription":[312,330,442],"altered":[314],"alternative":[315],"splicing":[316,426,445],"patterns":[317],"mRNAs.":[320,429],"splicing.":[333],"\\nThis":[334],"uncovered":[336],"involvement":[338],"two":[340,344],"very":[345],"distinct":[346],"first":[354,417],"report":[355,418],"suggesting":[356],"for":[359,385],"export.":[363,379],"Further":[364],"study":[365],"now":[367],"required":[368,433],"identify":[370],"cellular":[388,411],"other":[397,453],"also":[400],"warranted.":[401],"splicing,":[413],"indicating":[419],"may":[422],"be":[423],"Additional":[430],"work":[431],"define":[435],"precise":[437],"species.":[455]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
