{"id":"https://openalex.org/W1505756599","doi":null,"title":"Abstract 20027: Decellularized Aortic Allograft Vs. Pulmonary Autograft for Aortic Valve Replacement in Growing Sheep Model: Haemodynamic and Morphological Results After Implantation for 20 Months","display_name":"Abstract 20027: Decellularized Aortic Allograft Vs. Pulmonary Autograft for Aortic Valve Replacement in Growing Sheep Model: Haemodynamic and Morphological Results After Implantation for 20 Months","publication_year":2014,"publication_date":"2014-11-25","ids":{"openalex":"https://openalex.org/W1505756599","mag":"1505756599"},"language":"en","primary_location":{"id":"mag:1505756599","doi":null,"is_oa":false,"landing_page_url":"https://www.ahajournals.org/doi/abs/10.1161/circ.130.suppl_2.20027","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Circulation","raw_type":null},"volume":null,"type":"conference-abstract","is_traditional":false,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5079491654","display_name":"I. Tudorache","orcid":"https://orcid.org/0000-0002-7556-8229","observed_orcids":["https://orcid.org/0000-0002-7556-8229"]},"institutions":[{"id":"https://openalex.org/I34809795","display_name":"Medizinische Hochschule Hannover","ror":"https://ror.org/00f2yqf98","country_code":"DE","type":"education","lineage":["https://openalex.org/I34809795"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"I. Tudorache","raw_affiliation_strings":["1Cardiothoracic, Transplantation and Vascular Surgery, Medizinische Hochschule Hannover, Hannover, Germany"],"raw_orcid":"https://orcid.org/0000-0002-7556-8229","affiliations":[{"raw_affiliation_string":"1Cardiothoracic, Transplantation and Vascular Surgery, Medizinische Hochschule Hannover, Hannover, Germany","institution_ids":["https://openalex.org/I34809795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111014680","display_name":"Karolina Theodoridis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I34809795","display_name":"Medizinische Hochschule Hannover","ror":"https://ror.org/00f2yqf98","country_code":"DE","type":"education","lineage":["https://openalex.org/I34809795"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Karolina Theodoridis","raw_affiliation_strings":["1Cardiothoracic, Transplantation and Vascular Surgery, Medizinische Hochschule Hannover, Hannover, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Cardiothoracic, Transplantation and Vascular Surgery, Medizinische Hochschule Hannover, Hannover, Germany","institution_ids":["https://openalex.org/I34809795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033197648","display_name":"Samir Sarikouch","orcid":"https://orcid.org/0000-0001-7277-7597","observed_orcids":["https://orcid.org/0000-0001-7277-7597"]},"institutions":[{"id":"https://openalex.org/I34809795","display_name":"Medizinische Hochschule Hannover","ror":"https://ror.org/00f2yqf98","country_code":"DE","type":"education","lineage":["https://openalex.org/I34809795"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Samir Sarikouch","raw_affiliation_strings":["1Cardiothoracic, Transplantation and Vascular Surgery, Medizinische Hochschule Hannover, Hannover, Germany"],"raw_orcid":"https://orcid.org/0000-0001-7277-7597","affiliations":[{"raw_affiliation_string":"1Cardiothoracic, Transplantation and Vascular Surgery, Medizinische Hochschule Hannover, Hannover, Germany","institution_ids":["https://openalex.org/I34809795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5042625958","display_name":"Christoph Bara","orcid":"https://orcid.org/0000-0001-8905-7684","observed_orcids":["https://orcid.org/0000-0001-8905-7684"]},"institutions":[{"id":"https://openalex.org/I34809795","display_name":"Medizinische Hochschule Hannover","ror":"https://ror.org/00f2yqf98","country_code":"DE","type":"education","lineage":["https://openalex.org/I34809795"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Christoph Bara","raw_affiliation_strings":["1Cardiothoracic, Transplantation and Vascular Surgery, Medizinische Hochschule Hannover, Hannover, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Cardiothoracic, Transplantation and Vascular Surgery, Medizinische Hochschule Hannover, Hannover, Germany","institution_ids":["https://openalex.org/I34809795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109394420","display_name":"Tanja S. Meyer","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I34809795","display_name":"Medizinische Hochschule Hannover","ror":"https://ror.org/00f2yqf98","country_code":"DE","type":"education","lineage":["https://openalex.org/I34809795"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Tanja Meyer","raw_affiliation_strings":["1Cardiothoracic, Transplantation and Vascular Surgery, Medizinische Hochschule Hannover, Hannover, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Cardiothoracic, Transplantation and Vascular Surgery, Medizinische Hochschule Hannover, Hannover, Germany","institution_ids":["https://openalex.org/I34809795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081566492","display_name":"Klaus H\u00f6ffler","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I34809795","display_name":"Medizinische Hochschule Hannover","ror":"https://ror.org/00f2yqf98","country_code":"DE","type":"education","lineage":["https://openalex.org/I34809795"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Klaus H\u00f6ffler","raw_affiliation_strings":["1Cardiothoracic, Transplantation and Vascular Surgery, Medizinische Hochschule Hannover, Hannover, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Cardiothoracic, Transplantation and Vascular Surgery, Medizinische Hochschule Hannover, Hannover, Germany","institution_ids":["https://openalex.org/I34809795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111750625","display_name":"Dagmar Hartung","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I34809795","display_name":"Medizinische Hochschule Hannover","ror":"https://ror.org/00f2yqf98","country_code":"DE","type":"education","lineage":["https://openalex.org/I34809795"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Dagmar Hartung","raw_affiliation_strings":["2Radiology, Medizinische Hochschule Hannover, Hannover, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"2Radiology, Medizinische Hochschule Hannover, Hannover, Germany","institution_ids":["https://openalex.org/I34809795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5033411549","display_name":"Andres Hilfiker","orcid":"https://orcid.org/0000-0002-7123-2410","observed_orcids":["https://orcid.org/0000-0002-7123-2410"]},"institutions":[{"id":"https://openalex.org/I34809795","display_name":"Medizinische Hochschule Hannover","ror":"https://ror.org/00f2yqf98","country_code":"DE","type":"education","lineage":["https://openalex.org/I34809795"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Andres Hilfiker","raw_affiliation_strings":["1Cardiothoracic, Transplantation and Vascular Surgery, Medizinische Hochschule Hannover, Hannover, Germany"],"raw_orcid":"https://orcid.org/0000-0002-7123-2410","affiliations":[{"raw_affiliation_string":"1Cardiothoracic, Transplantation and Vascular Surgery, Medizinische Hochschule Hannover, Hannover, Germany","institution_ids":["https://openalex.org/I34809795"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109839319","display_name":"Axel Haverich","orcid":"https://orcid.org/0000-0002-0991-2650","observed_orcids":["https://orcid.org/0000-0002-0991-2650"]},"institutions":[{"id":"https://openalex.org/I34809795","display_name":"Medizinische Hochschule Hannover","ror":"https://ror.org/00f2yqf98","country_code":"DE","type":"education","lineage":["https://openalex.org/I34809795"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Axel Haverich","raw_affiliation_strings":["1Cardiothoracic, Transplantation and Vascular Surgery, Medizinische Hochschule Hannover, Hannover, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Cardiothoracic, Transplantation and Vascular Surgery, Medizinische Hochschule Hannover, Hannover, Germany","institution_ids":["https://openalex.org/I34809795"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5024318756","display_name":"Serghei Cebotari","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I34809795","display_name":"Medizinische Hochschule Hannover","ror":"https://ror.org/00f2yqf98","country_code":"DE","type":"education","lineage":["https://openalex.org/I34809795"]}],"countries":["DE"],"is_corresponding":false,"raw_author_name":"Serghei Cebotari","raw_affiliation_strings":["1Cardiothoracic, Transplantation and Vascular Surgery, Medizinische Hochschule Hannover, Hannover, Germany"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"1Cardiothoracic, Transplantation and Vascular Surgery, Medizinische Hochschule Hannover, Hannover, Germany","institution_ids":["https://openalex.org/I34809795"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I34809795"],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":"130","issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.7846999764442444,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T12264","display_name":"Tissue Engineering and Regenerative Medicine","score":0.7846999764442444,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10172","display_name":"Cardiac Valve Diseases and Treatments","score":0.1860000044107437,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10618","display_name":"Aortic Disease and Treatment Approaches","score":0.020999999716877937,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/pulmonary-autograft","display_name":"pulmonary autograft","score":0.9940000176429749},{"id":"https://openalex.org/keywords/aortic-valve-replacement","display_name":"aortic valve replacement","score":0.8960000276565552},{"id":"https://openalex.org/keywords/ross-procedure","display_name":"Ross procedure","score":0.9900000095367432},{"id":"https://openalex.org/keywords/hemodynamics","display_name":"hemodynamics","score":0.6869999766349792},{"id":"https://openalex.org/keywords/graft-immunology","display_name":"graft immunology","score":0.4009999930858612},{"id":"https://openalex.org/keywords/valve-insufficiency","display_name":"valve insufficiency","score":0.6019999980926514},{"id":"https://openalex.org/keywords/transvalvular-pressure-gradient","display_name":"transvalvular gradient","score":0.6919999718666077}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8180255889892578},{"id":"https://openalex.org/C190672674","wikidata":"https://www.wikidata.org/wiki/Q3866591","display_name":"Decellularization","level":3,"score":0.692497193813324},{"id":"https://openalex.org/C178853913","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Hemodynamics","level":2,"score":0.5871173143386841},{"id":"https://openalex.org/C2780714102","wikidata":"https://www.wikidata.org/wiki/Q616071","display_name":"Aortic valve","level":2,"score":0.5652675628662109},{"id":"https://openalex.org/C2776570981","wikidata":"https://www.wikidata.org/wiki/Q4413093","display_name":"Aortic valve replacement","level":3,"score":0.5323038101196289},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.46157750487327576},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.3778419494628906},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3230215311050415},{"id":"https://openalex.org/C49892992","wikidata":"https://www.wikidata.org/wiki/Q1540285","display_name":"Tissue engineering","level":2,"score":0.15228158235549927},{"id":"https://openalex.org/C2780007028","wikidata":"https://www.wikidata.org/wiki/Q2343082","display_name":"Stenosis","level":2,"score":0.10679349303245544},{"id":"https://openalex.org/C136229726","wikidata":"https://www.wikidata.org/wiki/Q327092","display_name":"Biomedical engineering","level":1,"score":0.1024584174156189}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:1505756599","doi":null,"is_oa":false,"landing_page_url":"https://www.ahajournals.org/doi/abs/10.1161/circ.130.suppl_2.20027","pdf_url":null,"source":{"id":"https://openalex.org/S116251202","display_name":"Circulation","issn_l":"0009-7322","issn":["0009-7322","1524-4539"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310315671","host_organization_name":"Lippincott Williams & Wilkins","host_organization_lineage":["https://openalex.org/P4310315671","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Lippincott Williams & Wilkins","Wolters Kluwer"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Circulation","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.6240000128746033,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1850747728","https://openalex.org/W2318841381","https://openalex.org/W120428669","https://openalex.org/W2072039655","https://openalex.org/W2277824627","https://openalex.org/W2010766417","https://openalex.org/W2000464667","https://openalex.org/W2073618498","https://openalex.org/W2092085731","https://openalex.org/W2029265156"],"abstract_inverted_index":{"Introduction:":[0],"Pulmonary":[1],"autograft":[2],"(PA)":[3],"represents":[4],"the":[5,31,50,169,209,213],"substitute":[6],"of":[7,36,142,151,160,165,203,208],"choice":[8],"for":[9,215],"aortic":[10,21,184,195],"valve":[11,57,103,196,210],"replacement":[12,59,197],"especially":[13],"in":[14,49,62,73,114,136,198,218],"children":[15],"and":[16,81,92,97,110,116,147,171,186,191],"young":[17],"adults.":[18],"Similarly,":[19],"decellularized":[20],"valves":[22],"(DAV)":[23],"showed":[24],"excellent":[25],"midterm":[26],"function":[27],"when":[28],"implanted":[29,121],"into":[30],"systemic":[32],"circulation.":[33],"The":[34,85,101,177],"aim":[35],"this":[37],"study":[38],"was":[39,60,180],"to":[40,43,108,112],"compare":[41],"DAVs":[42,67,115,166],"pulmonary":[44,187],"autografts":[45,188],"after":[46,194],"Ross":[47,74],"procedure":[48],"growing":[51,199],"sheep":[52],"model.\n\nMETHODS":[53],"AND":[54],"RESULTS:":[55],"Aortic":[56],"root":[58],"performed":[61],"lambs":[63],"(35-45kg)":[64],"using":[65],"either":[66],"(n=5)":[68,71],"or":[69],"PAs":[70],"as":[72],"procedure.":[75],"Haemodynamics":[76],"were":[77,87,134,154],"investigated":[78,93],"by":[79,94],"echocardiography":[80],"magnetic":[82],"resonance":[83],"imaging.":[84],"roots":[86],"explanted":[88],"at":[89,129,145,168],"20":[90],"months":[91],"histology,":[95],"immunohistochemistry,":[96],"transmission":[98],"electron":[99],"microscopy.":[100],"mean":[102,137],"diameter":[104],"increased":[105],"from":[106],"14":[107],"23mm":[109],"from15":[111],"25mm":[113],"PAs,":[117],"respectively.":[118],"Of":[119],"all":[120,152],"grafts,":[122],"only":[123],"one":[124],"PA":[125],"exhibited":[126],"moderate":[127],"insufficiency":[128],"explantation.":[130,149],"No":[131],"significant":[132],"differences":[133],"determined":[135],"transvalvular":[138],"gradient":[139],"between":[140],"grafts":[141],"both":[143,219],"groups":[144],"implantation":[146],"prior":[148],"Cusps":[150],"implants":[153],"soft,":[155],"pliable":[156],"without":[157,174],"gross":[158],"signs":[159],"degeneration.":[161],"Repopulation":[162],"with":[163],"cells":[164],"occurred":[167],"wall":[170],"cusp":[172],"level":[173],"immune":[175],"reaction.":[176],"endothelial":[178],"lining":[179],"regularly":[181],"restored.\n\nConclusion:":[182],"Decellularized":[183],"allografts":[185],"provide":[189],"adequate":[190],"comparable":[192],"haemodynamics":[193],"sheep.":[200],"Furthermore,":[201],"maintenance":[202],"valvular":[204],"competence":[205],"during":[206],"enlargement":[207],"ring":[211],"indicates":[212],"capacity":[214],"physiological":[216],"growth":[217],"graft":[220],"types.":[221]},"counts_by_year":[],"updated_date":"2026-09-22T06:50:58.402377","created_date":"2016-06-24T00:00:00"}
