{"id":"https://openalex.org/W1504355207","doi":"https://doi.org/10.1007/2789_2008_102","title":"Transcriptional Control and the Ubiquitin\u2013Proteasome System","display_name":"Transcriptional Control and the Ubiquitin\u2013Proteasome System","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W1504355207","doi":"https://doi.org/10.1007/2789_2008_102","mag":"1504355207","pmid":"https://pubmed.ncbi.nlm.nih.gov/19198065"},"language":"en","primary_location":{"id":"doi:10.1007/2789_2008_102","doi":"https://doi.org/10.1007/2789_2008_102","is_oa":false,"landing_page_url":"https://doi.org/10.1007/2789_2008_102","pdf_url":null,"source":{"id":"https://openalex.org/S4210183215","display_name":"Ernst Schering Research Foundation workshop/Ernst Schering Foundation Symposium proceedings","issn_l":"0947-6075","issn":["0947-6075","1860-8140","1866-9425"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ernst Schering Foundation Symposium Proceedings","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2502132480","display_name":"The Ubiquitin System in Health and Disease"},"type":"conference-paper","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016317673","display_name":"Amy Leung","orcid":"https://orcid.org/0000-0002-5175-430X","observed_orcids":["https://orcid.org/0000-0002-5175-430X"]},"institutions":[{"id":"https://openalex.org/I2750212522","display_name":"Cold Spring Harbor Laboratory","ror":"https://ror.org/02qz8b764","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2750212522"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Leung","raw_affiliation_strings":["Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY, 11724, USA","#N##TAB##TAB##TAB##TAB# Cold Spring Harbor Laboratory#N##TAB##TAB##TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY, 11724, USA","institution_ids":["https://openalex.org/I2750212522"]},{"raw_affiliation_string":"#N##TAB##TAB##TAB##TAB# Cold Spring Harbor Laboratory#N##TAB##TAB##TAB#","institution_ids":["https://openalex.org/I2750212522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077865454","display_name":"Fuqiang Geng","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2750212522","display_name":"Cold Spring Harbor Laboratory","ror":"https://ror.org/02qz8b764","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2750212522"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"F. Geng","raw_affiliation_strings":["Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY, 11724, USA","#N##TAB##TAB##TAB##TAB# Cold Spring Harbor Laboratory#N##TAB##TAB##TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY, 11724, USA","institution_ids":["https://openalex.org/I2750212522"]},{"raw_affiliation_string":"#N##TAB##TAB##TAB##TAB# Cold Spring Harbor Laboratory#N##TAB##TAB##TAB#","institution_ids":["https://openalex.org/I2750212522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5048622309","display_name":"Anne Daulny","orcid":"https://orcid.org/0000-0003-3387-7856","observed_orcids":["https://orcid.org/0000-0003-3387-7856"]},"institutions":[{"id":"https://openalex.org/I2750212522","display_name":"Cold Spring Harbor Laboratory","ror":"https://ror.org/02qz8b764","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2750212522"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"A. Daulny","raw_affiliation_strings":["Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY, 11724, USA","#N##TAB##TAB##TAB##TAB# Cold Spring Harbor Laboratory#N##TAB##TAB##TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY, 11724, USA","institution_ids":["https://openalex.org/I2750212522"]},{"raw_affiliation_string":"#N##TAB##TAB##TAB##TAB# Cold Spring Harbor Laboratory#N##TAB##TAB##TAB#","institution_ids":["https://openalex.org/I2750212522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010944849","display_name":"Galen Andrew Collins","orcid":"https://orcid.org/0000-0002-3926-9483","observed_orcids":["https://orcid.org/0000-0002-3926-9483"]},"institutions":[{"id":"https://openalex.org/I2750212522","display_name":"Cold Spring Harbor Laboratory","ror":"https://ror.org/02qz8b764","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2750212522"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"G. Collins","raw_affiliation_strings":["Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY, 11724, USA","#N##TAB##TAB##TAB##TAB# Cold Spring Harbor Laboratory#N##TAB##TAB##TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY, 11724, USA","institution_ids":["https://openalex.org/I2750212522"]},{"raw_affiliation_string":"#N##TAB##TAB##TAB##TAB# Cold Spring Harbor Laboratory#N##TAB##TAB##TAB#","institution_ids":["https://openalex.org/I2750212522"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108075919","display_name":"Paloma M. Guzzardo","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2750212522","display_name":"Cold Spring Harbor Laboratory","ror":"https://ror.org/02qz8b764","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2750212522"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"P. Guzzardo","raw_affiliation_strings":["Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY, 11724, USA","#N##TAB##TAB##TAB##TAB# Cold Spring Harbor Laboratory#N##TAB##TAB##TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY, 11724, USA","institution_ids":["https://openalex.org/I2750212522"]},{"raw_affiliation_string":"#N##TAB##TAB##TAB##TAB# Cold Spring Harbor Laboratory#N##TAB##TAB##TAB#","institution_ids":["https://openalex.org/I2750212522"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5049915899","display_name":"William P. Tansey","orcid":"https://orcid.org/0000-0002-3900-0978","observed_orcids":["https://orcid.org/0000-0002-3900-0978"]},"institutions":[{"id":"https://openalex.org/I2750212522","display_name":"Cold Spring Harbor Laboratory","ror":"https://ror.org/02qz8b764","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I2750212522"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"W. P. Tansey","raw_affiliation_strings":["Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY, 11724, USA","#N##TAB##TAB##TAB##TAB# Cold Spring Harbor Laboratory#N##TAB##TAB##TAB#"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cold Spring Harbor Laboratory, 1 Bungtown Road, Cold Spring Harbor, NY, 11724, USA","institution_ids":["https://openalex.org/I2750212522"]},{"raw_affiliation_string":"#N##TAB##TAB##TAB##TAB# Cold Spring Harbor Laboratory#N##TAB##TAB##TAB#","institution_ids":["https://openalex.org/I2750212522"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5049915899"],"corresponding_institution_ids":["https://openalex.org/I2750212522"],"apc_list":null,"apc_paid":null,"fwci":6.2487,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.95707237,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":89,"max":97},"biblio":{"volume":null,"issue":"1","first_page":"75","last_page":"97"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11041","display_name":"Ubiquitin and proteasome pathways","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11041","display_name":"Ubiquitin and proteasome pathways","score":0.9940999746322632,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10222","display_name":"Genomics and Chromatin Dynamics","score":0.00419999985024333,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10269","display_name":"Epigenetics and DNA Methylation","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transcriptional-regulation","display_name":"transcriptional regulation","score":0.8619999885559082},{"id":"https://openalex.org/keywords/ubiquitin-proteasome-system","display_name":"ubiquitin-proteasome system","score":0.9679999947547913},{"id":"https://openalex.org/keywords/ubiquitin","display_name":"ubiquitin","score":0.875},{"id":"https://openalex.org/keywords/proteasome","display_name":"proteasome","score":0.9909999966621399},{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.5329999923706055},{"id":"https://openalex.org/keywords/protein-degradation","display_name":"protein degradation","score":0.625}],"concepts":[{"id":"https://openalex.org/C27740335","wikidata":"https://www.wikidata.org/wiki/Q14878333","display_name":"Proteasome","level":2,"score":0.7434486150741577},{"id":"https://openalex.org/C25602115","wikidata":"https://www.wikidata.org/wiki/Q407111","display_name":"Ubiquitin","level":3,"score":0.7341234683990479},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5113460421562195},{"id":"https://openalex.org/C2775924081","wikidata":"https://www.wikidata.org/wiki/Q55608371","display_name":"Control (management)","level":2,"score":0.4722275733947754},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4168933033943176},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3759700059890747},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.2916455566883087},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.2505114674568176},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0863385796546936},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.05488637089729309}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D009369","descriptor_name":"Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014157","descriptor_name":"Transcription Factors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D025801","descriptor_name":"Ubiquitin","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D025801","descriptor_name":"Ubiquitin","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D046988","descriptor_name":"Proteasome Endopeptidase Complex","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D046988","descriptor_name":"Proteasome Endopeptidase Complex","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":3,"locations":[{"id":"doi:10.1007/2789_2008_102","doi":"https://doi.org/10.1007/2789_2008_102","is_oa":false,"landing_page_url":"https://doi.org/10.1007/2789_2008_102","pdf_url":null,"source":{"id":"https://openalex.org/S4210183215","display_name":"Ernst Schering Research Foundation workshop/Ernst Schering Foundation Symposium proceedings","issn_l":"0947-6075","issn":["0947-6075","1860-8140","1866-9425"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core"],"host_organization":"https://openalex.org/P4310319900","host_organization_name":"Springer Science+Business Media","host_organization_lineage":["https://openalex.org/P4310319900","https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Science+Business Media","Springer Nature"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ernst Schering Foundation Symposium Proceedings","raw_type":"book-chapter"},{"id":"pmid:19198065","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19198065","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Ernst Schering Foundation symposium proceedings","raw_type":"Journal Article"},{"id":"pmh:oai:repository.cshl.edu:27635","doi":null,"is_oa":false,"landing_page_url":"https://repository.cshl.edu/id/eprint/27635/","pdf_url":null,"source":{"id":"https://openalex.org/S4306402288","display_name":"Cold Spring Harbor Laboratory Institutional Repository (Cold Spring Harbor Laboratory)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I2750212522","host_organization_name":"Cold Spring Harbor Laboratory","host_organization_lineage":["https://openalex.org/I2750212522"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Paper"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G1200689522","display_name":null,"funder_award_id":"CA13106","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G5005785543","display_name":null,"funder_award_id":"GM-067728","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G756923313","display_name":null,"funder_award_id":"CA45508","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G8386752786","display_name":"Transcription Control by the Ubiquitin-Proteasome System","funder_award_id":"R01GM067728","funder_id":"https://openalex.org/F4320337354","funder_display_name":"National Institute of General Medical Sciences"},{"id":"https://openalex.org/G9000856157","display_name":"Targeting Transcription and Splicing in Cancer","funder_award_id":"P01CA013106","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G940439027","display_name":"CSHL Cancer Center Support Grant","funder_award_id":"5p30ca045508-35","funder_id":"https://openalex.org/F4320332161","funder_display_name":"National Institutes of Health"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"},{"id":"https://openalex.org/F4320337354","display_name":"National Institute of General Medical Sciences","ror":"https://ror.org/04q48ey07"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":69,"referenced_works":["https://openalex.org/W1497151945","https://openalex.org/W1507143828","https://openalex.org/W1507844821","https://openalex.org/W1515490675","https://openalex.org/W1562107474","https://openalex.org/W1749022239","https://openalex.org/W1914441096","https://openalex.org/W1963996414","https://openalex.org/W1964931840","https://openalex.org/W1966266513","https://openalex.org/W1970078607","https://openalex.org/W1972780353","https://openalex.org/W1977290507","https://openalex.org/W1977733856","https://openalex.org/W1983970621","https://openalex.org/W1987195602","https://openalex.org/W1988351397","https://openalex.org/W1991287841","https://openalex.org/W1992518796","https://openalex.org/W1992741271","https://openalex.org/W1999255494","https://openalex.org/W2002103750","https://openalex.org/W2005635949","https://openalex.org/W2013844573","https://openalex.org/W2016736163","https://openalex.org/W2021394112","https://openalex.org/W2028003321","https://openalex.org/W2033889343","https://openalex.org/W2037168837","https://openalex.org/W2038580923","https://openalex.org/W2038834815","https://openalex.org/W2039503906","https://openalex.org/W2040249554","https://openalex.org/W2044633101","https://openalex.org/W2049647279","https://openalex.org/W2050018101","https://openalex.org/W2050145162","https://openalex.org/W2050432515","https://openalex.org/W2053806606","https://openalex.org/W2056234356","https://openalex.org/W2059247879","https://openalex.org/W2060328159","https://openalex.org/W2064420752","https://openalex.org/W2065362756","https://openalex.org/W2067233094","https://openalex.org/W2073004429","https://openalex.org/W2078197564","https://openalex.org/W2080892506","https://openalex.org/W2082195309","https://openalex.org/W2082979850","https://openalex.org/W2087148381","https://openalex.org/W2087988002","https://openalex.org/W2089840805","https://openalex.org/W2092629648","https://openalex.org/W2096881442","https://openalex.org/W2099765629","https://openalex.org/W2102143993","https://openalex.org/W2119714784","https://openalex.org/W2127144150","https://openalex.org/W2132173502","https://openalex.org/W2132485651","https://openalex.org/W2135776390","https://openalex.org/W2138786316","https://openalex.org/W2145345398","https://openalex.org/W2149920358","https://openalex.org/W2154665053","https://openalex.org/W2158985006","https://openalex.org/W2172107732","https://openalex.org/W2356498392"],"related_works":["https://openalex.org/W2356498392","https://openalex.org/W2155080972","https://openalex.org/W1995953017","https://openalex.org/W2132529930","https://openalex.org/W3150581528","https://openalex.org/W2039675519","https://openalex.org/W7160468960","https://openalex.org/W1968406801","https://openalex.org/W2298206326","https://openalex.org/W1602690591"],"abstract_inverted_index":null,"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}