{"id":"https://openalex.org/W1504155896","doi":null,"title":"NF-\u03baB and cancer: a paradigm of Yin-Yang.","display_name":"NF-\u03baB and cancer: a paradigm of Yin-Yang.","publication_year":2011,"publication_date":"2011-01-01","ids":{"openalex":"https://openalex.org/W1504155896","mag":"1504155896","pmid":"https://pubmed.ncbi.nlm.nih.gov/21969033","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/3180046"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:2190466","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3180046","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3180046","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110164926","display_name":"Gutian Xiao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I170201317","display_name":"University of Pittsburgh","ror":"https://ror.org/01an3r305","country_code":"US","type":"education","lineage":["https://openalex.org/I170201317"]},{"id":"https://openalex.org/I4210128526","display_name":"UPMC Hillman Cancer Center","ror":"https://ror.org/03bw34a45","country_code":"US","type":"facility","lineage":["https://openalex.org/I170201317","https://openalex.org/I4210128526"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Gutian Xiao","raw_affiliation_strings":["University of Pittsburgh Cancer Institute, Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania 15213, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"University of Pittsburgh Cancer Institute, Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine Pittsburgh, Pennsylvania 15213, USA","institution_ids":["https://openalex.org/I170201317","https://openalex.org/I4210128526"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5102000057","display_name":"Jing Fu","orcid":"https://orcid.org/0000-0002-3894-722X","observed_orcids":["https://orcid.org/0000-0002-3894-722X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jing Fu","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.6373,"has_fulltext":false,"cited_by_count":94,"citation_normalized_percentile":{"value":0.89758841,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":99},"biblio":{"volume":"1","issue":"2","first_page":"192","last_page":"221"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11591","display_name":"NF-\u03baB Signaling Pathways","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11591","display_name":"NF-\u03baB Signaling Pathways","score":1.0,"subfield":{"id":"https://openalex.org/subfields/1306","display_name":"Cancer Research"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12620","display_name":"Signaling Pathways in Disease","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11501","display_name":"TGF-\u03b2 signaling in diseases","score":0.0,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nf-kappab","display_name":"NF-\u03baB","score":0.9980000257492065},{"id":"https://openalex.org/keywords/cancer","display_name":"cancer","score":0.5429999828338623},{"id":"https://openalex.org/keywords/carcinogenesis","display_name":"carcinogenesis","score":0.843999981880188},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.6690000295639038},{"id":"https://openalex.org/keywords/oncogene-activation","display_name":"oncogene activation","score":0.6489999890327454},{"id":"https://openalex.org/keywords/inflammation","display_name":"inflammation","score":0.5339999794960022},{"id":"https://openalex.org/keywords/tumor-surveillance","display_name":"tumor surveillance","score":0.9459999799728394},{"id":"https://openalex.org/keywords/transcription-factor-regulation","display_name":"transcription factor regulation","score":0.6259999871253967},{"id":"https://openalex.org/keywords/tumor-microenvironment","display_name":"tumor microenvironment","score":0.4580000042915344}],"concepts":[{"id":"https://openalex.org/C2776885095","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immunosurveillance","level":3,"score":0.8170808553695679},{"id":"https://openalex.org/C555283112","wikidata":"https://www.wikidata.org/wiki/Q1637543","display_name":"Carcinogenesis","level":3,"score":0.758956789970398},{"id":"https://openalex.org/C2777730290","wikidata":"https://www.wikidata.org/wiki/Q411114","display_name":"NF-\u03baB","level":3,"score":0.71149742603302},{"id":"https://openalex.org/C86339819","wikidata":"https://www.wikidata.org/wiki/Q407384","display_name":"Transcription factor","level":3,"score":0.6741082668304443},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.6734631061553955},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.581538200378418},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.5342309474945068},{"id":"https://openalex.org/C2779013556","wikidata":"https://www.wikidata.org/wiki/Q181876","display_name":"Metastasis","level":3,"score":0.4985802173614502},{"id":"https://openalex.org/C123298856","wikidata":"https://www.wikidata.org/wiki/Q15317427","display_name":"NFKB1","level":4,"score":0.47699645161628723},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.43802914023399353},{"id":"https://openalex.org/C2776914184","wikidata":"https://www.wikidata.org/wiki/Q101991","display_name":"Inflammation","level":2,"score":0.3738941550254822},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.320698082447052},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2946360111236572},{"id":"https://openalex.org/C3020616263","wikidata":"https://www.wikidata.org/wiki/Q1216998","display_name":"Tumor cells","level":2,"score":0.21598035097122192},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.15743225812911987},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.11522766947746277}],"mesh":[],"locations_count":4,"locations":[{"id":"pmh:oai:europepmc.org:2190466","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3180046","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:3180046","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3180046","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Am J Cancer Res","raw_type":"Text"},{"id":"pmid:21969033","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21969033","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"American journal of cancer research","raw_type":"Journal Article"},{"id":"mag:1504155896","doi":null,"is_oa":false,"landing_page_url":"https://europepmc.org/article/MED/21969033","pdf_url":null,"source":{"id":"https://openalex.org/S198195518","display_name":"American Journal of Cancer Research","issn_l":"2156-6976","issn":["2156-6976"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","norway-1","poland-100"],"host_organization":"https://openalex.org/P4310320994","host_organization_name":"e-Century Publishing Corporation","host_organization_lineage":["https://openalex.org/P4310320994"],"host_organization_lineage_names":["e-Century Publishing Corporation"],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"American Journal of Cancer Research","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:2190466","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/3180046","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"score":0.9476000070571899,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G5878003239","display_name":"HTLV deregulation of NF-kappaB2 p100 processing in tumor","funder_award_id":"R01CA116616","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":310,"referenced_works":["https://openalex.org/W38542969","https://openalex.org/W40139942","https://openalex.org/W40693379","https://openalex.org/W51542665","https://openalex.org/W64342747","https://openalex.org/W68080126","https://openalex.org/W87620544","https://openalex.org/W113665966","https://openalex.org/W165235925","https://openalex.org/W306915739","https://openalex.org/W432228268","https://openalex.org/W1482000562","https://openalex.org/W1501881225","https://openalex.org/W1520695706","https://openalex.org/W1537427513","https://openalex.org/W1547063277","https://openalex.org/W1554981631","https://openalex.org/W1563487810","https://openalex.org/W1580723864","https://openalex.org/W1596801838","https://openalex.org/W1607664081","https://openalex.org/W1617532721","https://openalex.org/W1661180389","https://openalex.org/W1782886592","https://openalex.org/W1810265271","https://openalex.org/W1829577351","https://openalex.org/W1846940228","https://openalex.org/W1892912865","https://openalex.org/W1911781926","https://openalex.org/W1922172635","https://openalex.org/W1938606373","https://openalex.org/W1964650077","https://openalex.org/W1965360199","https://openalex.org/W1968334977","https://openalex.org/W1969516822","https://openalex.org/W1969899671","https://openalex.org/W1969903944","https://openalex.org/W1970152161","https://openalex.org/W1970488098","https://openalex.org/W1970583256","https://openalex.org/W1971459774","https://openalex.org/W1971659365","https://openalex.org/W1971707389","https://openalex.org/W1972952746","https://openalex.org/W1973562447","https://openalex.org/W1974768393","https://openalex.org/W1975167804","https://openalex.org/W1976590012","https://openalex.org/W1976765363","https://openalex.org/W1978434703","https://openalex.org/W1979395827","https://openalex.org/W1979816280","https://openalex.org/W1980561309","https://openalex.org/W1981083415","https://openalex.org/W1982273913","https://openalex.org/W1985538305","https://openalex.org/W1985554302","https://openalex.org/W1985590990","https://openalex.org/W1986301169","https://openalex.org/W1987097007","https://openalex.org/W1987105149","https://openalex.org/W1987531976","https://openalex.org/W1988389975","https://openalex.org/W1989292072","https://openalex.org/W1990755038","https://openalex.org/W1992628946","https://openalex.org/W1993731501","https://openalex.org/W1993936200","https://openalex.org/W1994097988","https://openalex.org/W1994126393","https://openalex.org/W1994180393","https://openalex.org/W1994248843","https://openalex.org/W1995747121","https://openalex.org/W1996092482","https://openalex.org/W1996245793","https://openalex.org/W1996699413","https://openalex.org/W1996767494","https://openalex.org/W1997062461","https://openalex.org/W1998142094","https://openalex.org/W1998253936","https://openalex.org/W2000919345","https://openalex.org/W2001448769","https://openalex.org/W2002674047","https://openalex.org/W2002765078","https://openalex.org/W2002800994","https://openalex.org/W2004462371","https://openalex.org/W2004794374","https://openalex.org/W2006211913","https://openalex.org/W2006338784","https://openalex.org/W2007958260","https://openalex.org/W2008231783","https://openalex.org/W2008782135","https://openalex.org/W2010081774","https://openalex.org/W2011439123","https://openalex.org/W2013202536","https://openalex.org/W2015052875","https://openalex.org/W2016246269","https://openalex.org/W2016522022","https://openalex.org/W2016949937","https://openalex.org/W2017742161","https://openalex.org/W2018674722","https://openalex.org/W2019255422","https://openalex.org/W2019864071","https://openalex.org/W2020932061","https://openalex.org/W2021344005","https://openalex.org/W2023032337","https://openalex.org/W2026387078","https://openalex.org/W2026931388","https://openalex.org/W2027260180","https://openalex.org/W2027693396","https://openalex.org/W2028330103","https://openalex.org/W2029039230","https://openalex.org/W2029412954","https://openalex.org/W2029454644","https://openalex.org/W2029988348","https://openalex.org/W2030085084","https://openalex.org/W2030262603","https://openalex.org/W2031855605","https://openalex.org/W2033090511","https://openalex.org/W2033969079","https://openalex.org/W2034391818","https://openalex.org/W2034619319","https://openalex.org/W2034626843","https://openalex.org/W2035135710","https://openalex.org/W2035245019","https://openalex.org/W2035679764","https://openalex.org/W2035918677","https://openalex.org/W2036786326","https://openalex.org/W2037123014","https://openalex.org/W2038626045","https://openalex.org/W2039395669","https://openalex.org/W2039688872","https://openalex.org/W2042504292","https://openalex.org/W2042794796","https://openalex.org/W2043798682","https://openalex.org/W2043801813","https://openalex.org/W2044063668","https://openalex.org/W2044288124","https://openalex.org/W2044778854","https://openalex.org/W2045881743","https://openalex.org/W2046056065","https://openalex.org/W2046265685","https://openalex.org/W2046305482","https://openalex.org/W2046862219","https://openalex.org/W2048915877","https://openalex.org/W2049734724","https://openalex.org/W2050365970","https://openalex.org/W2050402493","https://openalex.org/W2051177828","https://openalex.org/W2051221156","https://openalex.org/W2051307540","https://openalex.org/W2051831012","https://openalex.org/W2052289997","https://openalex.org/W2052658654","https://openalex.org/W2052908553","https://openalex.org/W2053140018","https://openalex.org/W2055573606","https://openalex.org/W2056302937","https://openalex.org/W2056402897","https://openalex.org/W2057482139","https://openalex.org/W2059301162","https://openalex.org/W2059572643","https://openalex.org/W2060513667","https://openalex.org/W2060863314","https://openalex.org/W2060977243","https://openalex.org/W2061115519","https://openalex.org/W2061626409","https://openalex.org/W2062238060","https://openalex.org/W2062378348","https://openalex.org/W2062935439","https://openalex.org/W2064201629","https://openalex.org/W2064299413","https://openalex.org/W2065589361","https://openalex.org/W2067034566","https://openalex.org/W2068010171","https://openalex.org/W2068037459","https://openalex.org/W2069158176","https://openalex.org/W2069800916","https://openalex.org/W2070328448","https://openalex.org/W2071760372","https://openalex.org/W2072537237","https://openalex.org/W2073203272","https://openalex.org/W2073453659","https://openalex.org/W2073929635","https://openalex.org/W2074098407","https://openalex.org/W2074277423","https://openalex.org/W2075223145","https://openalex.org/W2075556692","https://openalex.org/W2076383117","https://openalex.org/W2076421117","https://openalex.org/W2076585881","https://openalex.org/W2077276508","https://openalex.org/W2077725608","https://openalex.org/W2078376874","https://openalex.org/W2079450955","https://openalex.org/W2079470363","https://openalex.org/W2079625864","https://openalex.org/W2080612514","https://openalex.org/W2081119041","https://openalex.org/W2081783036","https://openalex.org/W2083415193","https://openalex.org/W2083436757","https://openalex.org/W2083860480","https://openalex.org/W2084418060","https://openalex.org/W2084889194","https://openalex.org/W2085144387","https://openalex.org/W2085328161","https://openalex.org/W2085637098","https://openalex.org/W2085685524","https://openalex.org/W2087078985","https://openalex.org/W2087215271","https://openalex.org/W2088316325","https://openalex.org/W2089938437","https://openalex.org/W2090499247","https://openalex.org/W2091161875","https://openalex.org/W2092529209","https://openalex.org/W2093340006","https://openalex.org/W2093778278","https://openalex.org/W2094479138","https://openalex.org/W2095281683","https://openalex.org/W2096939339","https://openalex.org/W2097487635","https://openalex.org/W2097583243","https://openalex.org/W2098267886","https://openalex.org/W2101540252","https://openalex.org/W2103856686","https://openalex.org/W2103944436","https://openalex.org/W2104697096","https://openalex.org/W2106395252","https://openalex.org/W2106543129","https://openalex.org/W2108882588","https://openalex.org/W2108949452","https://openalex.org/W2109377963","https://openalex.org/W2110888067","https://openalex.org/W2111503158","https://openalex.org/W2111642458","https://openalex.org/W2114387248","https://openalex.org/W2114395749","https://openalex.org/W2114580401","https://openalex.org/W2116487940","https://openalex.org/W2117293778","https://openalex.org/W2118214974","https://openalex.org/W2118793608","https://openalex.org/W2121055529","https://openalex.org/W2123879591","https://openalex.org/W2124076790","https://openalex.org/W2126247355","https://openalex.org/W2126415922","https://openalex.org/W2126934083","https://openalex.org/W2127494207","https://openalex.org/W2128508005","https://openalex.org/W2129115963","https://openalex.org/W2129363220","https://openalex.org/W2129945166","https://openalex.org/W2130080333","https://openalex.org/W2130436812","https://openalex.org/W2131161803","https://openalex.org/W2132991384","https://openalex.org/W2133398398","https://openalex.org/W2135172903","https://openalex.org/W2135374261","https://openalex.org/W2135760822","https://openalex.org/W2135836598","https://openalex.org/W2136683006","https://openalex.org/W2136828863","https://openalex.org/W2137257146","https://openalex.org/W2137823685","https://openalex.org/W2138929006","https://openalex.org/W2139030718","https://openalex.org/W2140132827","https://openalex.org/W2141773149","https://openalex.org/W2142492088","https://openalex.org/W2142801414","https://openalex.org/W2146204355","https://openalex.org/W2147507133","https://openalex.org/W2148993356","https://openalex.org/W2150572026","https://openalex.org/W2150698399","https://openalex.org/W2152044329","https://openalex.org/W2152045576","https://openalex.org/W2152644051","https://openalex.org/W2158668670","https://openalex.org/W2158671377","https://openalex.org/W2159437901","https://openalex.org/W2160071194","https://openalex.org/W2160844806","https://openalex.org/W2161002061","https://openalex.org/W2161452134","https://openalex.org/W2163617004","https://openalex.org/W2164347552","https://openalex.org/W2164363164","https://openalex.org/W2167715370","https://openalex.org/W2171139781","https://openalex.org/W2232313291","https://openalex.org/W2234403833","https://openalex.org/W2291321734","https://openalex.org/W2315879546","https://openalex.org/W2318334567","https://openalex.org/W2321568747","https://openalex.org/W2326148782","https://openalex.org/W2327175308","https://openalex.org/W2332387324","https://openalex.org/W2333904918","https://openalex.org/W2409184083","https://openalex.org/W2409650525","https://openalex.org/W2415723858","https://openalex.org/W2558450893","https://openalex.org/W3171781738","https://openalex.org/W4313344654","https://openalex.org/W7095992443"],"related_works":["https://openalex.org/W2134062610","https://openalex.org/W1568548809","https://openalex.org/W1533021978","https://openalex.org/W2782630985","https://openalex.org/W2092460415","https://openalex.org/W4411619062","https://openalex.org/W20888715","https://openalex.org/W2007456673","https://openalex.org/W2884378719","https://openalex.org/W2315613727"],"abstract_inverted_index":{"Recent":[0],"studies":[1],"have":[2],"clearly":[3],"linked":[4],"nuclear":[5],"factor-kappaB":[6],"(NF-\u03baB),":[7],"a":[8,13],"transcription":[9],"factor":[10],"that":[11],"plays":[12],"central":[14],"role":[15],"in":[16,49,86,106],"regulating":[17],"immune":[18],"and":[19,26,51,73,83,103],"inflammatory":[20,102],"responses,":[21],"to":[22,62],"tumor":[23,31],"development,":[24],"progression,":[25],"metastasis":[27],"as":[28,30],"well":[29],"therapy":[32],"resistance.":[33],"However,":[34],"it":[35],"still":[36],"remains":[37],"largely":[38],"unknown":[39],"on":[40],"how":[41,52,98],"the":[42,53,80,87,101],"tightly":[43],"regulated":[44],"NF-\u03baB":[45,59,99],"becomes":[46],"constitutively":[47],"activated":[48],"tumorigenesis":[50],"original":[54],"cancer":[55,71],"immunosurveillance":[56],"function":[57],"of":[58,79,90,97],"is":[60],"transformed":[61],"be":[63],"tumorigenic.":[64],"To":[65],"address":[66],"these":[67],"important":[68],"issues":[69],"for":[70],"prevention":[72],"treatment,":[74],"we":[75],"discuss":[76,94],"current":[77,95],"understanding":[78,96],"molecular":[81],"mechanisms":[82],"molecules":[84],"involved":[85],"oncogenic":[88],"activation":[89],"NF-\u03baB.":[91],"We":[92],"also":[93],"coordinates":[100],"malignant":[104],"cells":[105],"tumorigenesis.":[107]},"counts_by_year":[{"year":2026,"cited_by_count":4},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":8},{"year":2020,"cited_by_count":4},{"year":2019,"cited_by_count":5},{"year":2018,"cited_by_count":7},{"year":2017,"cited_by_count":7},{"year":2016,"cited_by_count":9},{"year":2015,"cited_by_count":12},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":12},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-08T12:12:28.789561","created_date":"2016-06-24T00:00:00"}
