{"id":"https://openalex.org/W1504092302","doi":"https://doi.org/10.1128/jvi.53.1.94-99.1985","title":"Comparison of endogenous murine leukemia virus proviral organization and RNA expression in 3-methylcholanthrene-induced and spontaneous thymic lymphomas in RF and AKR mice","display_name":"Comparison of endogenous murine leukemia virus proviral organization and RNA expression in 3-methylcholanthrene-induced and spontaneous thymic lymphomas in RF and AKR mice","publication_year":1985,"publication_date":"1985-01-01","ids":{"openalex":"https://openalex.org/W1504092302","doi":"https://doi.org/10.1128/jvi.53.1.94-99.1985","mag":"1504092302","pmid":"https://pubmed.ncbi.nlm.nih.gov/2981367","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/254983"},"language":"en","primary_location":{"id":"doi:10.1128/jvi.53.1.94-99.1985","doi":"https://doi.org/10.1128/jvi.53.1.94-99.1985","is_oa":true,"landing_page_url":"https://doi.org/10.1128/jvi.53.1.94-99.1985","pdf_url":"https://jvi.asm.org/content/jvi/53/1/94.full.pdf","source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://jvi.asm.org/content/jvi/53/1/94.full.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5075362058","display_name":"Jeffrey M. Chinsky","orcid":"https://orcid.org/0000-0003-2344-2306","observed_orcids":["https://orcid.org/0000-0003-2344-2306"]},"institutions":[{"id":"https://openalex.org/I19772626","display_name":"Yeshiva University","ror":"https://ror.org/045x93337","country_code":"US","type":"education","lineage":["https://openalex.org/I19772626"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"J Chinsky","raw_affiliation_strings":["Yeshiva University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yeshiva University","institution_ids":["https://openalex.org/I19772626"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5000314616","display_name":"Maureen M. Goodenow","orcid":"https://orcid.org/0000-0002-4750-9627","observed_orcids":["https://orcid.org/0000-0002-4750-9627"]},"institutions":[{"id":"https://openalex.org/I19772626","display_name":"Yeshiva University","ror":"https://ror.org/045x93337","country_code":"US","type":"education","lineage":["https://openalex.org/I19772626"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M M Goodenow","raw_affiliation_strings":["Yeshiva University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yeshiva University","institution_ids":["https://openalex.org/I19772626"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112690990","display_name":"M Jackson","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I19772626","display_name":"Yeshiva University","ror":"https://ror.org/045x93337","country_code":"US","type":"education","lineage":["https://openalex.org/I19772626"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"M Jackson","raw_affiliation_strings":["Yeshiva University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Yeshiva University","institution_ids":["https://openalex.org/I19772626"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111562500","display_name":"F Lilly","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"F Lilly","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5085095319","display_name":"Leslie Anne Leinwand","orcid":"https://orcid.org/0000-0003-1470-4810","observed_orcids":["https://orcid.org/0000-0003-1470-4810"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"L Leinwand","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5044237462","display_name":"Geoffrey J. Childs","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"G Childs","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.1122,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.76229438,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"53","issue":"1","first_page":"94","last_page":"99"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies","score":0.9961000084877014,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.0024999999441206455,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10185","display_name":"Lymphoma Diagnosis and Treatment","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2734","display_name":"Pathology and Forensic Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/murine-leukemia-virus","display_name":"murine leukemia virus","score":0.9399999976158142},{"id":"https://openalex.org/keywords/thymic-lymphoma","display_name":"thymic lymphoma","score":0.871999979019165},{"id":"https://openalex.org/keywords/3-methylcholanthrene","display_name":"3-methylcholanthrene","score":0.9259999990463257},{"id":"https://openalex.org/keywords/ecotropic-mulv","display_name":"ecotropic MuLV","score":0.8040000200271606},{"id":"https://openalex.org/keywords/long-terminal-repeat","display_name":"long terminal repeat","score":0.6790000200271606},{"id":"https://openalex.org/keywords/rf-mice","display_name":"RF mice","score":0.8370000123977661},{"id":"https://openalex.org/keywords/akr-mice","display_name":"AKR mice","score":0.9980000257492065}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8652334213256836},{"id":"https://openalex.org/C2779562191","wikidata":"https://www.wikidata.org/wiki/Q673848","display_name":"Murine leukemia virus","level":3,"score":0.7846153974533081},{"id":"https://openalex.org/C102906071","wikidata":"https://www.wikidata.org/wiki/Q422467","display_name":"Provirus","level":4,"score":0.6662633419036865},{"id":"https://openalex.org/C67705224","wikidata":"https://www.wikidata.org/wiki/Q11053","display_name":"RNA","level":3,"score":0.5827739834785461},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.5771732926368713},{"id":"https://openalex.org/C121346293","wikidata":"https://www.wikidata.org/wiki/Q1340715","display_name":"Endogenous retrovirus","level":4,"score":0.563423216342926},{"id":"https://openalex.org/C552990157","wikidata":"https://www.wikidata.org/wiki/Q7430","display_name":"DNA","level":2,"score":0.5255250334739685},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.501422643661499},{"id":"https://openalex.org/C199491388","wikidata":"https://www.wikidata.org/wiki/Q1869477","display_name":"Long terminal repeat","level":4,"score":0.4769022464752197},{"id":"https://openalex.org/C2780754187","wikidata":"https://www.wikidata.org/wiki/Q17700","display_name":"Mink","level":2,"score":0.4729937016963959},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.46282702684402466},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.45884478092193604},{"id":"https://openalex.org/C2780303067","wikidata":"https://www.wikidata.org/wiki/Q223099","display_name":"Methylcholanthrene","level":3,"score":0.45757031440734863},{"id":"https://openalex.org/C2778431562","wikidata":"https://www.wikidata.org/wiki/Q189308","display_name":"Retrovirus","level":3,"score":0.4435759484767914},{"id":"https://openalex.org/C16613235","wikidata":"https://www.wikidata.org/wiki/Q285982","display_name":"Endogeny","level":2,"score":0.41029587388038635},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.35225969552993774},{"id":"https://openalex.org/C150194340","wikidata":"https://www.wikidata.org/wiki/Q26972","display_name":"Gene expression","level":3,"score":0.29859304428100586},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16856446862220764},{"id":"https://openalex.org/C141231307","wikidata":"https://www.wikidata.org/wiki/Q7020","display_name":"Genome","level":3,"score":0.13460081815719604},{"id":"https://openalex.org/C114246631","wikidata":"https://www.wikidata.org/wiki/Q187661","display_name":"Carcinogen","level":2,"score":0.11163678765296936},{"id":"https://openalex.org/C18903297","wikidata":"https://www.wikidata.org/wiki/Q7150","display_name":"Ecology","level":1,"score":0.0},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000406","descriptor_name":"AKR murine leukemia virus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001483","descriptor_name":"Base Sequence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002460","descriptor_name":"Cell Line","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004262","descriptor_name":"DNA Restriction Enzymes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005814","descriptor_name":"Genes, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007942","descriptor_name":"Leukemia, Experimental","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D008223","descriptor_name":"Lymphoma","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":false},{"descriptor_ui":"D008748","descriptor_name":"Methylcholanthrene","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008806","descriptor_name":"Mice, Inbred AKR","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008815","descriptor_name":"Mice, Inbred Strains","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009052","descriptor_name":"Leukemia Virus, Murine","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D009693","descriptor_name":"Nucleic Acid Hybridization","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013953","descriptor_name":"Thymus Neoplasms","qualifier_ui":"Q000382","qualifier_name":"microbiology","is_major_topic":true},{"descriptor_ui":"D014158","descriptor_name":"Transcription, Genetic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"doi:10.1128/jvi.53.1.94-99.1985","doi":"https://doi.org/10.1128/jvi.53.1.94-99.1985","is_oa":true,"landing_page_url":"https://doi.org/10.1128/jvi.53.1.94-99.1985","pdf_url":"https://jvi.asm.org/content/jvi/53/1/94.full.pdf","source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:254983","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/254983","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Virol","raw_type":"Text"},{"id":"pmid:2981367","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/2981367","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of virology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1128/jvi.53.1.94-99.1985","doi":"https://doi.org/10.1128/jvi.53.1.94-99.1985","is_oa":true,"landing_page_url":"https://doi.org/10.1128/jvi.53.1.94-99.1985","pdf_url":"https://jvi.asm.org/content/jvi/53/1/94.full.pdf","source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":0.504800021648407,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G1950000034","display_name":"MECHANISMS OF CHEMICAL LYMPHOMAGENESIS","funder_award_id":"P01CA031855","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1504092302.pdf"},"referenced_works_count":31,"referenced_works":["https://openalex.org/W203701027","https://openalex.org/W1507530049","https://openalex.org/W1535366269","https://openalex.org/W1543411722","https://openalex.org/W1568047344","https://openalex.org/W1593026388","https://openalex.org/W1755157643","https://openalex.org/W1916039573","https://openalex.org/W1968230732","https://openalex.org/W1978119836","https://openalex.org/W1981316974","https://openalex.org/W1998971747","https://openalex.org/W2012792526","https://openalex.org/W2014969466","https://openalex.org/W2028082957","https://openalex.org/W2029987769","https://openalex.org/W2045490425","https://openalex.org/W2048330520","https://openalex.org/W2055478880","https://openalex.org/W2058810523","https://openalex.org/W2061311391","https://openalex.org/W2063450941","https://openalex.org/W2068793381","https://openalex.org/W2120818994","https://openalex.org/W2136029008","https://openalex.org/W2136590274","https://openalex.org/W2144634347","https://openalex.org/W2145976561","https://openalex.org/W2148472148","https://openalex.org/W2155645215","https://openalex.org/W2158759865"],"related_works":["https://openalex.org/W1492524150","https://openalex.org/W1964151753","https://openalex.org/W2021119692","https://openalex.org/W2169999866","https://openalex.org/W1627545763","https://openalex.org/W1909390158","https://openalex.org/W2133384327","https://openalex.org/W2432471313","https://openalex.org/W1910373072","https://openalex.org/W2087226065"],"abstract_inverted_index":{"3-Methylcholanthrene-induced":[0],"T-cell":[1],"thymic":[2,121],"lymphomas":[3],"in":[4,17,115,125,165,175],"RF":[5,166],"mice":[6,167,177],"were":[7,34],"examined":[8],"for":[9],"involvement":[10,182],"of":[11,22,29,55,67,136,157,183],"murine":[12],"leukemia":[13],"virus":[14,105],"(MuLV)-related":[15],"sequences":[16],"leukemogenesis.":[18],"Both":[19],"the":[20,27,85,171,181],"expression":[21,107],"MuLV-related":[23,45],"RNA":[24,46,57,73],"species":[25,47,58,74],"and":[26,93,142],"organization":[28],"endogenous":[30,158,184],"MuLV":[31,79,92,159,185],"proviral":[32,149],"DNA":[33,63,137,150],"analyzed.":[35],"Of":[36],"27":[37],"primary":[38,119,140],"tumors":[39,70,123,141],"examined,":[40],"only":[41],"5":[42],"exhibited":[43],"elevated":[44],"homologous":[48],"to":[49,88,146,180],"xenotropic":[50],"specific":[51],"env":[52,153],"DNA.":[53],"None":[54],"these":[56,68],"hybridized":[59,76],"with":[60,77,111,151,178],"ecotropic":[61,78,91],"p15E":[62],"sequences.":[64,186],"Only":[65],"two":[66],"five":[69],"contained":[71],"MuLV-like":[72],"that":[75],"long":[80],"terminal":[81],"repeat":[82],"sequences,":[83],"despite":[84],"probe's":[86],"ability":[87],"detect":[89],"both":[90,139],"mink":[94,102],"cell":[95,103,128,143],"focus-inducing":[96,104],"viral":[97],"RNA.":[98],"No":[99],"muLV":[100],"resembling":[101],"whose":[106],"could":[108],"be":[109],"correlated":[110],"lymphomagenesis":[112,164],"was":[113],"detected":[114],"either":[116,148],"preleukemic":[117],"thymocytes,":[118],"3-methylcholanthrene-induced":[120],"tumors,":[122],"passaged":[124],"vivo,":[126],"or":[127,155],"lines":[129,144],"derived":[130],"from":[131,138,170],"tumors.":[132],"Restriction":[133],"endonuclease":[134],"analysis":[135],"failed":[145],"reveal":[147],"recombinant":[152],"genes":[154],"rearrangement":[156],"proviruses.":[160],"Therefore,":[161],"chemically":[162],"induced":[163],"appears":[168],"different":[169],"spontaneous":[172],"lymphomagenic":[173],"process":[174],"AKR":[176],"respect":[179]},"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}