{"id":"https://openalex.org/W1503164232","doi":"https://doi.org/10.1111/j.1369-1600.2010.00241.x","title":"High cocaine dosage decreases neurogenesis in the hippocampus and impairs working memory","display_name":"High cocaine dosage decreases neurogenesis in the hippocampus and impairs working memory","publication_year":2010,"publication_date":"2010-08-23","ids":{"openalex":"https://openalex.org/W1503164232","doi":"https://doi.org/10.1111/j.1369-1600.2010.00241.x","mag":"1503164232","pmid":"https://pubmed.ncbi.nlm.nih.gov/20731634"},"language":"en","primary_location":{"id":"doi:10.1111/j.1369-1600.2010.00241.x","doi":"https://doi.org/10.1111/j.1369-1600.2010.00241.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1369-1600.2010.00241.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1369-1600.2010.00241.x","source":{"id":"https://openalex.org/S118332200","display_name":"Addiction Biology","issn_l":"1355-6215","issn":["1355-6215","1369-1600"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Addiction Biology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1369-1600.2010.00241.x","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5061902089","display_name":"Einav Sudai","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Einav Sudai","raw_affiliation_strings":["Neuropharmacology Laboratory, The Mina & Everard Goodman Faculty of Life Sciences, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuropharmacology Laboratory, The Mina & Everard Goodman Faculty of Life Sciences, Israel","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5020508452","display_name":"Ofri Croitoru","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ofri Croitoru","raw_affiliation_strings":["Neuropharmacology Laboratory, The Mina & Everard Goodman Faculty of Life Sciences, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuropharmacology Laboratory, The Mina & Everard Goodman Faculty of Life Sciences, Israel","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088307130","display_name":"Alona Shaldubina","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Alona Shaldubina","raw_affiliation_strings":["The Leslie and Susan Gonda (Goldschmied) Multidisciplinary Brain Research Center, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"The Leslie and Susan Gonda (Goldschmied) Multidisciplinary Brain Research Center, Israel","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5001878324","display_name":"Lital Abraham","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Lital Abraham","raw_affiliation_strings":["Neuropharmacology Laboratory, The Mina & Everard Goodman Faculty of Life Sciences, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuropharmacology Laboratory, The Mina & Everard Goodman Faculty of Life Sciences, Israel","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5077845472","display_name":"Iris Herman Gispan","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Iris Gispan","raw_affiliation_strings":["Neuropharmacology Laboratory, The Mina & Everard Goodman Faculty of Life Sciences, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuropharmacology Laboratory, The Mina & Everard Goodman Faculty of Life Sciences, Israel","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5054315278","display_name":"Yakov Flaumenhaft","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Yakov Flaumenhaft","raw_affiliation_strings":["Neuropharmacology Laboratory, The Mina & Everard Goodman Faculty of Life Sciences, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuropharmacology Laboratory, The Mina & Everard Goodman Faculty of Life Sciences, Israel","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5014482587","display_name":"Ilana Roth\u2010Deri","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Ilana Roth\u2010Deri","raw_affiliation_strings":["Neuropharmacology Laboratory, The Mina & Everard Goodman Faculty of Life Sciences, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuropharmacology Laboratory, The Mina & Everard Goodman Faculty of Life Sciences, Israel","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5037209358","display_name":"Noa Kinor","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Noa Kinor","raw_affiliation_strings":["Neuropharmacology Laboratory, The Mina & Everard Goodman Faculty of Life Sciences, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuropharmacology Laboratory, The Mina & Everard Goodman Faculty of Life Sciences, Israel","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062071547","display_name":"Shai Aharoni","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Shai Aharoni","raw_affiliation_strings":["Neuropharmacology Laboratory, The Mina & Everard Goodman Faculty of Life Sciences, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuropharmacology Laboratory, The Mina & Everard Goodman Faculty of Life Sciences, Israel","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5016035389","display_name":"Moshe Ben\u2010Tzion","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I13955877","display_name":"Bar-Ilan University","ror":"https://ror.org/03kgsv495","country_code":"IL","type":"education","lineage":["https://openalex.org/I13955877"]}],"countries":["IL"],"is_corresponding":false,"raw_author_name":"Moshe Ben\u2010Tzion","raw_affiliation_strings":["Department of Chemistry, Bar-Ilan University, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Chemistry, Bar-Ilan University, Israel","institution_ids":["https://openalex.org/I13955877"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5088336881","display_name":"Gal Yadid","orcid":"https://orcid.org/0000-0002-4379-8505","observed_orcids":["https://orcid.org/0000-0002-4379-8505"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Gal Yadid","raw_affiliation_strings":["Neuropharmacology Laboratory, The Mina & Everard Goodman Faculty of Life Sciences, Israel","The Leslie and Susan Gonda (Goldschmied) Multidisciplinary Brain Research Center, Israel"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Neuropharmacology Laboratory, The Mina & Everard Goodman Faculty of Life Sciences, Israel","institution_ids":[]},{"raw_affiliation_string":"The Leslie and Susan Gonda (Goldschmied) Multidisciplinary Brain Research Center, Israel","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":["https://openalex.org/A5088336881"],"corresponding_institution_ids":[],"apc_list":{"value":3150,"currency":"USD","value_usd":3150},"apc_paid":null,"fwci":2.1263,"has_fulltext":true,"cited_by_count":82,"citation_normalized_percentile":{"value":0.85608424,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":93,"max":99},"biblio":{"volume":"16","issue":"2","first_page":"251","last_page":"260"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10608","display_name":"Neurogenesis and neuroplasticity mechanisms","score":0.9955999851226807,"subfield":{"id":"https://openalex.org/subfields/2806","display_name":"Developmental Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10056","display_name":"Neurotransmitter Receptor Influence on Behavior","score":0.0020000000949949026,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10448","display_name":"Memory and Neural Mechanisms","score":0.00039999998989515007,"subfield":{"id":"https://openalex.org/subfields/2805","display_name":"Cognitive Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cocaine","display_name":"cocaine","score":0.9950000047683716},{"id":"https://openalex.org/keywords/neurogenesis","display_name":"neurogenesis","score":0.640999972820282},{"id":"https://openalex.org/keywords/hippocampus","display_name":"hippocampus","score":0.9160000085830688},{"id":"https://openalex.org/keywords/dentate-gyrus","display_name":"dentate gyrus","score":0.9430000185966492},{"id":"https://openalex.org/keywords/working-memory","display_name":"working memory","score":0.9359999895095825},{"id":"https://openalex.org/keywords/drug-dosage","display_name":"drug dosing","score":0.5609999895095825},{"id":"https://openalex.org/keywords/cell-proliferation","display_name":"cell proliferation","score":0.628000020980835},{"id":"https://openalex.org/keywords/drug-addiction","display_name":"drug addiction","score":0.6800000071525574},{"id":"https://openalex.org/keywords/abstinence","display_name":"abstinence","score":0.7139999866485596},{"id":"https://openalex.org/keywords/learning-and-memory","display_name":"learning and memory","score":0.6269999742507935}],"concepts":[{"id":"https://openalex.org/C4746552","wikidata":"https://www.wikidata.org/wiki/Q1456827","display_name":"Neurogenesis","level":2,"score":0.9267630577087402},{"id":"https://openalex.org/C2776464000","wikidata":"https://www.wikidata.org/wiki/Q545787","display_name":"Dentate gyrus","level":3,"score":0.804021954536438},{"id":"https://openalex.org/C2781161787","wikidata":"https://www.wikidata.org/wiki/Q48360","display_name":"Hippocampus","level":2,"score":0.8014136552810669},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.6884023547172546},{"id":"https://openalex.org/C48856860","wikidata":"https://www.wikidata.org/wiki/Q12029","display_name":"Addiction","level":2,"score":0.6799630522727966},{"id":"https://openalex.org/C15744967","wikidata":"https://www.wikidata.org/wiki/Q9418","display_name":"Psychology","level":0,"score":0.5663647651672363}],"mesh":[{"descriptor_ui":"D000697","descriptor_name":"Central Nervous System Stimulants","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002455","descriptor_name":"Cell Division","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D003042","descriptor_name":"Cocaine","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D004305","descriptor_name":"Dose-Response Relationship, Drug","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D006624","descriptor_name":"Hippocampus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008570","descriptor_name":"Memory, Short-Term","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D008570","descriptor_name":"Memory, Short-Term","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012646","descriptor_name":"Self Administration","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013375","descriptor_name":"Substance Withdrawal Syndrome","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018765","descriptor_name":"Dopamine Uptake Inhibitors","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D018782","descriptor_name":"Maze Learning","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D018782","descriptor_name":"Maze Learning","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D018891","descriptor_name":"Dentate Gyrus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D018891","descriptor_name":"Dentate Gyrus","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D019970","descriptor_name":"Cocaine-Related Disorders","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":true},{"descriptor_ui":"D019970","descriptor_name":"Cocaine-Related Disorders","qualifier_ui":"Q000523","qualifier_name":"psychology","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D055495","descriptor_name":"Neurogenesis","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D055495","descriptor_name":"Neurogenesis","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1369-1600.2010.00241.x","doi":"https://doi.org/10.1111/j.1369-1600.2010.00241.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1369-1600.2010.00241.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1369-1600.2010.00241.x","source":{"id":"https://openalex.org/S118332200","display_name":"Addiction Biology","issn_l":"1355-6215","issn":["1355-6215","1369-1600"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Addiction Biology","raw_type":"journal-article"},{"id":"pmid:20731634","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/20731634","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Addiction biology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1111/j.1369-1600.2010.00241.x","doi":"https://doi.org/10.1111/j.1369-1600.2010.00241.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1369-1600.2010.00241.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1369-1600.2010.00241.x","source":{"id":"https://openalex.org/S118332200","display_name":"Addiction Biology","issn_l":"1355-6215","issn":["1355-6215","1369-1600"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-c","doyens","jufo-2","ki-jl-1","medline","norway-1","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Addiction Biology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320321449","display_name":"Bar-Ilan University","ror":"https://ror.org/03kgsv495"},{"id":"https://openalex.org/F4320323944","display_name":"Ministry of Health, State of Israel","ror":"https://ror.org/016n0q862"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1503164232.pdf","grobid_xml":"https://content.openalex.org/works/W1503164232.grobid-xml"},"referenced_works_count":43,"referenced_works":["https://openalex.org/W1561258900","https://openalex.org/W1670625131","https://openalex.org/W1704778993","https://openalex.org/W1813867068","https://openalex.org/W1968375954","https://openalex.org/W1975274954","https://openalex.org/W1978631167","https://openalex.org/W1980492003","https://openalex.org/W1983226940","https://openalex.org/W1991249144","https://openalex.org/W2003292964","https://openalex.org/W2006942542","https://openalex.org/W2012389501","https://openalex.org/W2019888004","https://openalex.org/W2025604203","https://openalex.org/W2031550956","https://openalex.org/W2045788878","https://openalex.org/W2049372723","https://openalex.org/W2053068006","https://openalex.org/W2054749214","https://openalex.org/W2055117351","https://openalex.org/W2055887456","https://openalex.org/W2057135100","https://openalex.org/W2064323269","https://openalex.org/W2065754676","https://openalex.org/W2070794162","https://openalex.org/W2072060777","https://openalex.org/W2073068789","https://openalex.org/W2078070194","https://openalex.org/W2089482332","https://openalex.org/W2096547256","https://openalex.org/W2100636840","https://openalex.org/W2103081123","https://openalex.org/W2105619265","https://openalex.org/W2128160796","https://openalex.org/W2129789527","https://openalex.org/W2136108338","https://openalex.org/W2140592478","https://openalex.org/W2148727841","https://openalex.org/W2151422895","https://openalex.org/W2153533547","https://openalex.org/W2166346862","https://openalex.org/W2415636866"],"related_works":["https://openalex.org/W2610917075","https://openalex.org/W2045656102","https://openalex.org/W2064323269","https://openalex.org/W2342965781","https://openalex.org/W2326474043","https://openalex.org/W7098625781","https://openalex.org/W2982951105","https://openalex.org/W2948194747","https://openalex.org/W1968660479","https://openalex.org/W2170608366"],"abstract_inverted_index":{"Drug":[0],"addiction":[1,21],"is":[2,22,50],"a":[3,72],"chronic":[4],"brain":[5],"disorder,":[6],"characterized":[7],"by":[8],"the":[9,12,27,31,34,53,66,80,94,98,107,121,126,136,144],"loss":[10],"of":[11,20,30,47,52,57,63,82,85,97,140],"ability":[13],"to":[14,25,120],"control":[15],"drug":[16],"consumption.":[17],"The":[18],"neurobiology":[19],"traditionally":[23],"thought":[24],"involve":[26],"mesocorticolimbic":[28],"system":[29],"brain.":[32],"However,":[33],"hippocampus":[35,68,99],"has":[36],"received":[37],"renewed":[38],"interest":[39],"for":[40],"its":[41],"potential":[42],"role":[43],"in":[44,65,93,111,118,125,131,143],"addiction.":[45],"Part":[46],"this":[48],"attention":[49],"because":[51],"fact":[54],"that":[55,116],"drugs":[56],"abuse":[58],"are":[59],"potent":[60],"negative":[61],"regulators":[62],"neurogenesis":[64,92],"adult":[67,112],"and":[69,76,91,100,138,146],"may":[70],"as":[71],"result":[73],"impair":[74],"learning":[75],"memory.":[77,149],"We":[78,114],"investigated":[79],"effects":[81],"different":[83],"dosages":[84],"contingent":[86],"cocaine":[87],"on":[88,101],"cell":[89],"proliferation":[90],"dentate":[95],"gyrus":[96],"working":[102,148],"memory":[103],"during":[104],"abstinence,":[105],"using":[106],"water":[108],"T-maze":[109],"test,":[110],"rats.":[113],"found":[115],"cocaine,":[117],"addition":[119],"changes":[122],"it":[123],"produces":[124],"reward":[127],"system,":[128],"if":[129],"taken":[130],"high":[132],"doses,":[133],"can":[134],"attenuate":[135],"production":[137],"development":[139],"new":[141],"neurons":[142],"hippocampus,":[145],"reduce":[147]},"counts_by_year":[{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":4},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":5},{"year":2020,"cited_by_count":9},{"year":2019,"cited_by_count":2},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":9},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":3},{"year":2014,"cited_by_count":12},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":11}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}