{"id":"https://openalex.org/W1502852025","doi":null,"title":"Study of the impact of oseltamivir on the risk for pneumonia and other outcomes of influenza, 2000-2005.","display_name":"Study of the impact of oseltamivir on the risk for pneumonia and other outcomes of influenza, 2000-2005.","publication_year":2008,"publication_date":"2008-06-04","ids":{"openalex":"https://openalex.org/W1502852025","mag":"1502852025","pmid":"https://pubmed.ncbi.nlm.nih.gov/18679536","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2491667"},"language":"en","primary_location":{"id":"pmid:18679536","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18679536","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medscape journal of medicine","raw_type":"Comparative Study"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2491667/","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5065800405","display_name":"Patrick H. Peters","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Patrick H Peters","raw_affiliation_strings":["Texas Medical Research Associates L.L.C., San Antonio, Texas, USA. PPeters856@aol.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Texas Medical Research Associates L.L.C., San Antonio, Texas, USA. PPeters856@aol.com","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079683892","display_name":"Anne Moscona","orcid":"https://orcid.org/0000-0002-1796-8320","observed_orcids":["https://orcid.org/0000-0002-1796-8320"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Anne Moscona","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112477201","display_name":"Kathy L. Schulman","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kathy L Schulman","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5039002709","display_name":"Charles E. Barr","orcid":"https://orcid.org/0000-0001-9883-1897","observed_orcids":["https://orcid.org/0000-0001-9883-1897"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Charles E Barr","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":2.2051,"has_fulltext":false,"cited_by_count":30,"citation_normalized_percentile":{"value":0.85596501,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"10","issue":"6","first_page":"131","last_page":"131"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10167","display_name":"Influenza Virus Research Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10167","display_name":"Influenza Virus Research Studies","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11243","display_name":"Respiratory viral infections research","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10654","display_name":"Pneumonia and Respiratory Infections","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/oseltamivir","display_name":"oseltamivir","score":0.9210000038146973},{"id":"https://openalex.org/keywords/influenza","display_name":"influenza","score":0.9139999747276306},{"id":"https://openalex.org/keywords/antiviral-therapy","display_name":"antiviral therapy","score":0.9120000004768372},{"id":"https://openalex.org/keywords/pneumonia","display_name":"pneumonia","score":0.8080000281333923},{"id":"https://openalex.org/keywords/otitis-media","display_name":"otitis media","score":0.824999988079071},{"id":"https://openalex.org/keywords/hospitalization","display_name":"hospitalization","score":0.7429999709129333},{"id":"https://openalex.org/keywords/influenza-complications","display_name":"influenza complications","score":0.7730000019073486},{"id":"https://openalex.org/keywords/respiratory-diseases","display_name":"respiratory diseases","score":0.7649999856948853},{"id":"https://openalex.org/keywords/health-care-expenditure","display_name":"health care expenditure","score":0.7139999866485596},{"id":"https://openalex.org/keywords/children","display_name":"children","score":0.8560000061988831},{"id":"https://openalex.org/keywords/health-insurance-claims-data","display_name":"health insurance claims data","score":0.6859999895095825},{"id":"https://openalex.org/keywords/propensity-score-matching","display_name":"propensity score matching","score":0.39500001072883606}],"concepts":[{"id":"https://openalex.org/C2780374985","wikidata":"https://www.wikidata.org/wiki/Q211509","display_name":"Oseltamivir","level":5,"score":0.9362372756004333},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8632125854492188},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6391311883926392},{"id":"https://openalex.org/C82789193","wikidata":"https://www.wikidata.org/wiki/Q2142611","display_name":"Relative risk","level":3,"score":0.6333531141281128},{"id":"https://openalex.org/C2777914695","wikidata":"https://www.wikidata.org/wiki/Q12192","display_name":"Pneumonia","level":2,"score":0.5742756128311157},{"id":"https://openalex.org/C44249647","wikidata":"https://www.wikidata.org/wiki/Q208498","display_name":"Confidence interval","level":2,"score":0.5495921969413757},{"id":"https://openalex.org/C2779343474","wikidata":"https://www.wikidata.org/wiki/Q3109175","display_name":"Context (archaeology)","level":2,"score":0.5330179333686829},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.5311564207077026},{"id":"https://openalex.org/C2426938","wikidata":"https://www.wikidata.org/wiki/Q3355478","display_name":"Medical prescription","level":2,"score":0.48678991198539734},{"id":"https://openalex.org/C50382708","wikidata":"https://www.wikidata.org/wiki/Q223218","display_name":"Proportional hazards model","level":2,"score":0.44874829053878784},{"id":"https://openalex.org/C201903717","wikidata":"https://www.wikidata.org/wiki/Q1778788","display_name":"Cohort study","level":2,"score":0.43423566222190857},{"id":"https://openalex.org/C3008058167","wikidata":"https://www.wikidata.org/wiki/Q84263196","display_name":"Coronavirus disease 2019 (COVID-19)","level":4,"score":0.11500224471092224},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.09454548358917236},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.06029999256134033},{"id":"https://openalex.org/C524204448","wikidata":"https://www.wikidata.org/wiki/Q788926","display_name":"Infectious disease (medical specialty)","level":3,"score":0.05232095718383789},{"id":"https://openalex.org/C151730666","wikidata":"https://www.wikidata.org/wiki/Q7205","display_name":"Paleontology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000998","descriptor_name":"Antiviral Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007251","descriptor_name":"Influenza, Human","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D007251","descriptor_name":"Influenza, Human","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D007251","descriptor_name":"Influenza, Human","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011014","descriptor_name":"Pneumonia","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D011014","descriptor_name":"Pneumonia","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D011014","descriptor_name":"Pneumonia","qualifier_ui":"Q000517","qualifier_name":"prevention & control","is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015331","descriptor_name":"Cohort Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016896","descriptor_name":"Treatment Outcome","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D053139","descriptor_name":"Oseltamivir","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:18679536","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18679536","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medscape journal of medicine","raw_type":"Comparative Study"},{"id":"pmh:oai:pubmedcentral.nih.gov:2491667","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2491667/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medscape J Med","raw_type":"Text"},{"id":"mag:1502852025","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18679536","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2491667","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC2491667/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Medscape J Med","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Observational Study","id":"https://openalex.org/study-designs/observational-study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":42,"referenced_works":["https://openalex.org/W121585274","https://openalex.org/W181573057","https://openalex.org/W1886211768","https://openalex.org/W1969595878","https://openalex.org/W1974879176","https://openalex.org/W1977775160","https://openalex.org/W1980500906","https://openalex.org/W1981513529","https://openalex.org/W2000445173","https://openalex.org/W2004554957","https://openalex.org/W2010284659","https://openalex.org/W2026309239","https://openalex.org/W2029292325","https://openalex.org/W2040210640","https://openalex.org/W2045197177","https://openalex.org/W2048679896","https://openalex.org/W2051796467","https://openalex.org/W2056207626","https://openalex.org/W2058144955","https://openalex.org/W2065420324","https://openalex.org/W2072658090","https://openalex.org/W2075704126","https://openalex.org/W2080927210","https://openalex.org/W2082036062","https://openalex.org/W2089030557","https://openalex.org/W2092237993","https://openalex.org/W2095981561","https://openalex.org/W2100620897","https://openalex.org/W2101366722","https://openalex.org/W2103031068","https://openalex.org/W2104244770","https://openalex.org/W2107176478","https://openalex.org/W2116911900","https://openalex.org/W2124198996","https://openalex.org/W2126822076","https://openalex.org/W2130441728","https://openalex.org/W2132542802","https://openalex.org/W2138003466","https://openalex.org/W2139841187","https://openalex.org/W2404764639","https://openalex.org/W2952905171","https://openalex.org/W4298928527"],"related_works":["https://openalex.org/W2097373894","https://openalex.org/W2069686304","https://openalex.org/W2155379386","https://openalex.org/W2076867675","https://openalex.org/W2095981561","https://openalex.org/W2038967598","https://openalex.org/W4235882368","https://openalex.org/W3035426551","https://openalex.org/W2096199944","https://openalex.org/W2473067680"],"abstract_inverted_index":{"CONTEXT:":[0],"Influenza":[1],"results":[2],"in":[3,178,221,234],"large":[4],"numbers":[5],"of":[6,16,64,78,88,136,138,181,251,261],"secondary":[7],"complications":[8,20,166,253],"and":[9,21,83,86,95,122,161,164,183,198,237,254],"hospitalizations.":[10],"OBJECTIVE:":[11],"To":[12],"assess":[13],"the":[14,42,93,134,222,227,235,248],"impact":[15],"oseltamivir":[17,60,94,121,223,236],"on":[18],"influenza-related":[19,252],"hospitalizations":[22],"by":[23,140,153,167,213],"analyzing":[24],"health":[25],"insurance":[26],"claims":[27,39],"data":[28,40,48],"for":[29,92,106,187],"6":[30],"influenza":[31,44,65],"seasons.":[32,45],"DESIGN:":[33],"A":[34],"retrospective":[35],"cohort":[36],"study":[37],"utilizing":[38],"from":[41,51],"2000-2005":[43],"SETTING:":[46],"Claims":[47],"were":[49,67,90,123,185,211,241],"obtained":[50],"Thomson":[52],"Healthcare":[53],"MarketScan":[54],"Research":[55],"Databases.":[56],"PATIENTS:":[57],"Patients":[58],"prescribed":[59,71,257],"within":[61],"1":[62],"day":[63],"diagnosis":[66,137],"compared":[68,91,225],"to":[69,126],"those":[70],"no":[72,96,129,228,238],"antiviral":[73,97,130,229,239],"therapy":[74],"(controls).":[75],"OUTCOMES:":[76],"Frequencies":[77],"pneumonia,":[79],"other":[80,150],"respiratory":[81,151],"illnesses,":[82],"otitis":[84,162],"media,":[85],"rates":[87,210],"hospitalization,":[89],"groups.":[98],"Expenditure":[99],"was":[100,109],"also":[101],"analyzed.":[102],"Relative":[103],"risk":[104,135,250],"(RR)":[105],"each":[107],"outcome":[108],"assessed":[110],"using":[111],"Cox":[112],"proportional":[113],"hazards":[114],"regression.":[115],"RESULTS:":[116],"Overall,":[117,208],"31,674":[118],"patients":[119,127],"received":[120],"propensity":[124],"matched":[125],"with":[128,226],"prescription.":[131],"Oseltamivir":[132,246],"reduced":[133,212,247],"pneumonia":[139,179],"15%":[141],"(RR":[142,155,169,192,201,215],"0.85,":[143],"95%":[144,157,171,194,203,217],"confidence":[145],"interval":[146],"[CI]":[147],"0.73,":[148],"0.98),":[149],"illnesses":[152],"20%":[154],"0.80,":[156],"CI:":[158,172,195,204,218],"0.76,":[159],"0.83),":[160],"media":[163],"its":[165],"31%":[168],"0.69,":[170],"0.61,":[173],"0.79).":[174],"The":[175],"greatest":[176],"reductions":[177],"risk,":[180],"57%":[182],"52%,":[184],"observed":[186],"children":[188],"aged":[189],"6-12":[190],"years":[191,200],"0.43,":[193],"0.26,":[196],"0.71)":[197],"1-2":[199],"0.48,":[202],"0.24,":[205],"0.99),":[206],"respectively.":[207],"hospitalization":[209,255],"38%":[214],"0.62,":[216],"0.52,":[219],"0.74)":[220],"group":[224],"group.":[230],"Total":[231],"adjusted":[232],"expenditures":[233],"groups":[240],"not":[242],"significantly":[243],"different.":[244],"CONCLUSIONS:":[245],"relative":[249],"when":[256],"immediately":[258],"upon":[259],"presentation":[260],"influenza.":[262]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":2},{"year":2012,"cited_by_count":5}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}