{"id":"https://openalex.org/W150172269","doi":"https://doi.org/10.1007/978-1-4757-2582-7_1","title":"Permeability of the Blood-Brain Barrier to Circulating Free Fatty Acids","display_name":"Permeability of the Blood-Brain Barrier to Circulating Free Fatty Acids","publication_year":1997,"publication_date":"1997-01-01","ids":{"openalex":"https://openalex.org/W150172269","doi":"https://doi.org/10.1007/978-1-4757-2582-7_1","mag":"150172269"},"language":"en","primary_location":{"id":"doi:10.1007/978-1-4757-2582-7_1","doi":"https://doi.org/10.1007/978-1-4757-2582-7_1","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4757-2582-7_1","pdf_url":null,"source":{"id":"https://openalex.org/S4306463399","display_name":"Humana Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315801","host_organization_name":"Humana Press","host_organization_lineage":["https://openalex.org/P4310315801","https://openalex.org/P4310319900"],"host_organization_lineage_names":["Humana Press","Springer Science+Business Media"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Handbook of Essential Fatty Acid Biology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W2491644137","display_name":"Handbook of Essential Fatty Acid Biology"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5054959155","display_name":"William A. Banks","orcid":"https://orcid.org/0000-0002-0496-3619","observed_orcids":["https://orcid.org/0000-0002-0496-3619"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"William A. Banks","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032152107","display_name":"Abba J. Kastin","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Abba J. Kastin","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5105414771","display_name":"Stanley Isaac Rapoport","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Stanley I. Rapoport","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.7943,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.83534137,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":null,"issue":null,"first_page":"3","last_page":"14"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11872","display_name":"Barrier Structure and Function Studies","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2808","display_name":"Neurology"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10387","display_name":"Fatty Acid Research and Health","score":0.000699999975040555,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10570","display_name":"Drug Transport and Resistance Mechanisms","score":0.0006000000284984708,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/blood-brain-barrier","display_name":"blood-brain barrier","score":0.9800000190734863},{"id":"https://openalex.org/keywords/free-fatty-acids","display_name":"free fatty acids","score":0.968999981880188},{"id":"https://openalex.org/keywords/brain-fatty-acid-metabolism","display_name":"brain fatty acid metabolism","score":0.9319999814033508}],"concepts":[{"id":"https://openalex.org/C2778402981","wikidata":"https://www.wikidata.org/wiki/Q221694","display_name":"Blood\u2013brain barrier","level":3,"score":0.8014247417449951},{"id":"https://openalex.org/C120882062","wikidata":"https://www.wikidata.org/wiki/Q28352","display_name":"Permeability (electromagnetism)","level":3,"score":0.49381765723228455},{"id":"https://openalex.org/C169760540","wikidata":"https://www.wikidata.org/wiki/Q207011","display_name":"Neuroscience","level":1,"score":0.44758808612823486},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4460045397281647},{"id":"https://openalex.org/C62231903","wikidata":"https://www.wikidata.org/wiki/Q1057","display_name":"Metabolism","level":2,"score":0.41645684838294983},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.39208269119262695},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3184601068496704},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2693522572517395},{"id":"https://openalex.org/C529278444","wikidata":"https://www.wikidata.org/wiki/Q47273","display_name":"Central nervous system","level":2,"score":0.14561566710472107},{"id":"https://openalex.org/C41625074","wikidata":"https://www.wikidata.org/wiki/Q176088","display_name":"Membrane","level":2,"score":0.05481955409049988}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1007/978-1-4757-2582-7_1","doi":"https://doi.org/10.1007/978-1-4757-2582-7_1","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-1-4757-2582-7_1","pdf_url":null,"source":{"id":"https://openalex.org/S4306463399","display_name":"Humana Press eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310315801","host_organization_name":"Humana Press","host_organization_lineage":["https://openalex.org/P4310315801","https://openalex.org/P4310319900"],"host_organization_lineage_names":["Humana Press","Springer Science+Business Media"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Handbook of Essential Fatty Acid Biology","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9391000270843506,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":50,"referenced_works":["https://openalex.org/W1063220","https://openalex.org/W166071099","https://openalex.org/W264483085","https://openalex.org/W640170556","https://openalex.org/W965024924","https://openalex.org/W1490336136","https://openalex.org/W1541446070","https://openalex.org/W1603776666","https://openalex.org/W1666690834","https://openalex.org/W1964863479","https://openalex.org/W1964919630","https://openalex.org/W1968531694","https://openalex.org/W1971307443","https://openalex.org/W1975195966","https://openalex.org/W1980410488","https://openalex.org/W1992469267","https://openalex.org/W1994991276","https://openalex.org/W2001567447","https://openalex.org/W2005390270","https://openalex.org/W2009295700","https://openalex.org/W2010377986","https://openalex.org/W2016291243","https://openalex.org/W2017037574","https://openalex.org/W2019505196","https://openalex.org/W2022868578","https://openalex.org/W2025680807","https://openalex.org/W2033406189","https://openalex.org/W2034891698","https://openalex.org/W2039736891","https://openalex.org/W2040294687","https://openalex.org/W2040683695","https://openalex.org/W2057743936","https://openalex.org/W2060371158","https://openalex.org/W2066136648","https://openalex.org/W2071383579","https://openalex.org/W2078877172","https://openalex.org/W2087264002","https://openalex.org/W2088077128","https://openalex.org/W2135884645","https://openalex.org/W2181591541","https://openalex.org/W2288113889","https://openalex.org/W2294335852","https://openalex.org/W2324040239","https://openalex.org/W2325257210","https://openalex.org/W2346847393","https://openalex.org/W2396250046","https://openalex.org/W2401055714","https://openalex.org/W2405280951","https://openalex.org/W2418277597","https://openalex.org/W3022037017"],"related_works":["https://openalex.org/W194894686","https://openalex.org/W1955938972","https://openalex.org/W2040294687","https://openalex.org/W2598814368","https://openalex.org/W2073400782","https://openalex.org/W4241278586","https://openalex.org/W1495489270","https://openalex.org/W2095260583","https://openalex.org/W2992917092","https://openalex.org/W2231442599"],"abstract_inverted_index":{"The":[0,21],"uptake":[1],"and":[2,18,55,69],"incorporation":[3],"by":[4],"brain":[5,28,64],"of":[6,23,46],"blood-borne":[7],"free":[8],"fatty":[9],"acids":[10],"(FFA)":[11],"is":[12],"a":[13],"topic":[14],"with":[15],"important":[16],"physiological":[17],"diagnostic":[19],"ramifications.":[20],"passage":[22],"FFA":[24,53,65],"from":[25],"blood":[26],"into":[27],"requires":[29],"penetration":[30],"through":[31],"the":[32,39,44,47],"blood-brain":[33],"barrier":[34],"(BBB).":[35],"We":[36],"review":[37],"here":[38],"basic":[40],"principles":[41,58],"that":[42],"underlie":[43],"concept":[45],"BBB":[48],"as":[49],"they":[50],"apply":[51],"to":[52,62],"permeability":[54],"how":[56],"such":[57],"can":[59],"be":[60],"used":[61],"study":[63],"metabolism":[66],"in":[67],"health":[68],"disease.":[70]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":1},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-10T09:11:00.788812","created_date":"2016-06-24T00:00:00"}