{"id":"https://openalex.org/W1501473386","doi":null,"title":"Paediatric organophosphate poisoning--a rural hospital experience.","display_name":"Paediatric organophosphate poisoning--a rural hospital experience.","publication_year":2005,"publication_date":"2005-09-01","ids":{"openalex":"https://openalex.org/W1501473386","mag":"1501473386","pmid":"https://pubmed.ncbi.nlm.nih.gov/16327926"},"language":"en","primary_location":{"id":"pmid:16327926","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16327926","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5012226355","display_name":"Ricky Dippenaar","orcid":"https://orcid.org/0000-0003-2191-9158","observed_orcids":["https://orcid.org/0000-0003-2191-9158"]},"institutions":[{"id":"https://openalex.org/I4210092469","display_name":"Tygerberg Children\u2019s Hospital","ror":"https://ror.org/00je08x63","country_code":"ZA","type":"healthcare","lineage":["https://openalex.org/I4210092469"]}],"countries":["ZA"],"is_corresponding":false,"raw_author_name":"R Dippenaar","raw_affiliation_strings":["Tygerberg Children's Hospital, Tygerberg, Western Cape, South Africa. rickydip@sun.ac.za"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tygerberg Children's Hospital, Tygerberg, Western Cape, South Africa. rickydip@sun.ac.za","institution_ids":["https://openalex.org/I4210092469"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5012767733","display_name":"Ralph Diedericks","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"R J Diedericks","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":24.4251,"has_fulltext":false,"cited_by_count":622,"citation_normalized_percentile":{"value":0.99948151,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":100},"biblio":{"volume":"95","issue":"9","first_page":"678","last_page":"81"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10875","display_name":"Pesticide Exposure and Toxicity","score":0.7666000127792358,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10875","display_name":"Pesticide Exposure and Toxicity","score":0.7666000127792358,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11635","display_name":"Poisoning and overdose treatments","score":0.22059999406337738,"subfield":{"id":"https://openalex.org/subfields/2711","display_name":"Emergency Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13639","display_name":"Paraquat toxicity studies and treatments","score":0.002300000051036477,"subfield":{"id":"https://openalex.org/subfields/3005","display_name":"Toxicology"},"field":{"id":"https://openalex.org/fields/30","display_name":"Pharmacology, Toxicology and Pharmaceutics"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/organophosphate-poisoning","display_name":"organophosphate poisoning","score":0.9789999723434448},{"id":"https://openalex.org/keywords/pediatric-poisoning","display_name":"pediatric poisoning","score":0.9660000205039978},{"id":"https://openalex.org/keywords/atropine-toxicity","display_name":"atropine toxicity","score":0.925000011920929},{"id":"https://openalex.org/keywords/atropine","display_name":"atropine","score":0.5139999985694885},{"id":"https://openalex.org/keywords/glycopyrrolate","display_name":"glycopyrrolate","score":0.8740000128746033},{"id":"https://openalex.org/keywords/pesticide-ingestion","display_name":"pesticide ingestion","score":0.6399999856948853},{"id":"https://openalex.org/keywords/seasonal-variation","display_name":"seasonal variation","score":0.6959999799728394},{"id":"https://openalex.org/keywords/butyrylcholinesterase","display_name":"butyrylcholinesterase","score":0.8610000014305115},{"id":"https://openalex.org/keywords/length-of-hospital-stay","display_name":"length of hospital stay","score":0.5630000233650208},{"id":"https://openalex.org/keywords/pesticide-exposure","display_name":"pesticide exposure","score":0.43700000643730164},{"id":"https://openalex.org/keywords/fruit-production","display_name":"fruit growing","score":0.7160000205039978},{"id":"https://openalex.org/keywords/rural-hospitals","display_name":"rural hospitals","score":0.4449999928474426}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8855283260345459},{"id":"https://openalex.org/C2775859210","wikidata":"https://www.wikidata.org/wiki/Q26272","display_name":"Atropine","level":2,"score":0.6972019672393799},{"id":"https://openalex.org/C2778736120","wikidata":"https://www.wikidata.org/wiki/Q3153685","display_name":"Organophosphate poisoning","level":4,"score":0.5978649258613586},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.5113970637321472},{"id":"https://openalex.org/C167135981","wikidata":"https://www.wikidata.org/wiki/Q2146302","display_name":"Retrospective cohort study","level":2,"score":0.4954286813735962},{"id":"https://openalex.org/C23131810","wikidata":"https://www.wikidata.org/wiki/Q818574","display_name":"Observational study","level":2,"score":0.46908584237098694},{"id":"https://openalex.org/C187155963","wikidata":"https://www.wikidata.org/wiki/Q629029","display_name":"Occupational safety and health","level":2,"score":0.4324090778827667},{"id":"https://openalex.org/C2908993608","wikidata":"https://www.wikidata.org/wiki/Q45959","display_name":"Accidental poisoning","level":4,"score":0.42203211784362793},{"id":"https://openalex.org/C2777601897","wikidata":"https://www.wikidata.org/wiki/Q3409113","display_name":"Presentation (obstetrics)","level":2,"score":0.4102354049682617},{"id":"https://openalex.org/C194828623","wikidata":"https://www.wikidata.org/wiki/Q2861470","display_name":"Emergency medicine","level":1,"score":0.39966335892677307},{"id":"https://openalex.org/C3017944768","wikidata":"https://www.wikidata.org/wiki/Q1450463","display_name":"Poison control","level":2,"score":0.37292060256004333},{"id":"https://openalex.org/C2776588719","wikidata":"https://www.wikidata.org/wiki/Q411097","display_name":"Organophosphate","level":3,"score":0.37275248765945435},{"id":"https://openalex.org/C190385971","wikidata":"https://www.wikidata.org/wiki/Q373494","display_name":"Injury prevention","level":3,"score":0.34315019845962524},{"id":"https://openalex.org/C161176658","wikidata":"https://www.wikidata.org/wiki/Q131656","display_name":"Pesticide","level":2,"score":0.3371523916721344},{"id":"https://openalex.org/C42219234","wikidata":"https://www.wikidata.org/wiki/Q131130","display_name":"Anesthesia","level":1,"score":0.30175474286079407},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.22617200016975403},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.14177998900413513},{"id":"https://openalex.org/C6557445","wikidata":"https://www.wikidata.org/wiki/Q173113","display_name":"Agronomy","level":1,"score":0.0},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.0},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000383","descriptor_name":"Agriculture","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001285","descriptor_name":"Atropine","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D001285","descriptor_name":"Atropine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007306","descriptor_name":"Insecticides","qualifier_ui":"Q000506","qualifier_name":"poisoning","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011041","descriptor_name":"Poisoning","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D011041","descriptor_name":"Poisoning","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D011041","descriptor_name":"Poisoning","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012621","descriptor_name":"Seasons","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013019","descriptor_name":"South Africa","qualifier_ui":"Q000453","qualifier_name":"epidemiology","is_major_topic":false},{"descriptor_ui":"D018727","descriptor_name":"Muscarinic Antagonists","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D018727","descriptor_name":"Muscarinic Antagonists","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D062025","descriptor_name":"Organophosphate Poisoning","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"pmid:16327926","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16327926","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde","raw_type":"Journal Article"},{"id":"mag:1501473386","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16327926","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":1.0}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W3115647326","https://openalex.org/W2042824048","https://openalex.org/W2188339910","https://openalex.org/W4286511903","https://openalex.org/W2087031687","https://openalex.org/W1777266335","https://openalex.org/W2518684051","https://openalex.org/W2103781759","https://openalex.org/W2396487614","https://openalex.org/W4417089540"],"abstract_inverted_index":{"OBJECTIVES:":[0],"To":[1],"document":[2],"the":[3,16,67,71,79,109,113,136,149,161,224,231,263],"presentation":[4,141,238],"and":[5,13,144,239],"course":[6],"of":[7,18,30,35,70,108,125,140,154,160,180,197,223,233,248,278],"organophosphate":[8],"poisoning":[9,119],"(OPP)":[10],"in":[11,66,158],"children":[12,88,187],"to":[14,38,50,148,190,218,230,252,254],"record":[15],"frequency":[17],"atropine":[19,155,175],"toxicity":[20,156],"during":[21],"treatment.":[22],"DESIGN:":[23],"A":[24,127],"retrospective":[25],"observational":[26],"study":[27,56,85],"was":[28,57,131,142,145,172,182],"conducted":[29,58],"all":[31,87],"recorded":[32],"paediatric":[33],"cases":[34,110,163],"OPP":[36],"admitted":[37],"a":[39,43,63,200,206,255,276],"regional":[40,64],"hospital":[41,65],"over":[42],"5-year":[44],"period":[45],"from":[46,112,199],"1":[47],"June":[48],"1996":[49],"31":[51],"May":[52],"2001.":[53],"SETTING:":[54],"The":[55,84,177,194,250],"at":[59],"Eben":[60],"Donges":[61],"Hospital,":[62],"Boland/Overberg":[68],"area":[69,116,213],"Western":[72],"Cape,":[73],"where":[74,214],"pesticide-intensive":[75],"fruit":[76],"farming":[77],"remains":[78],"largest":[80],"revenue":[81],"generator.":[82],"SUBJECTS.":[83],"included":[86],"aged":[89],"12":[90],"years":[91],"or":[92],"less":[93],"(as":[94],"per":[95],"health":[96],"services":[97],"classification)":[98],"with":[99,118,135,165,185,205,246,268],"confirmed":[100],"OPP.":[101],"RESULTS:":[102],"There":[103],"were":[104],"23":[105],"patients.":[106],"Most":[107],"came":[111],"De":[114],"Doorns":[115],"(35%),":[117],"by":[120],"ingestion":[121,209],"accounting":[122],"for":[123,174],"61%":[124,207],"cases.":[126],"distinct":[128],"seasonal":[129,225],"predominance":[130,226],"found":[132,173],"that":[133],"coincided":[134],"summer":[137],"harvest.":[138],"Mode":[139],"variable":[143],"not":[146,244],"related":[147],"initial":[150],"pseudocholinesterase":[151,241],"level.":[152],"Evidence":[153],"occurred":[157],"8":[159],"18":[162],"treated":[164],"atropine.":[166,269],"No":[167],"statistically":[168],"significant":[169],"risk":[170,277],"factor":[171],"toxicity.":[176,279],"average":[178],"duration":[179,247],"hospitalisation":[181],"5.05":[183],"days,":[184],"2":[186],"requiring":[188],"transfer":[189,253],"tertiary":[191,256],"facilities.":[192],"CONCLUSIONS:":[193],"high":[195],"number":[196],"referrals":[198],"specific":[201],"geographical":[202],"area,":[203],"combined":[204],"accidental":[208],"rate,":[210],"illustrates":[211],"an":[212,283],"legislation":[215],"has":[216,265],"failed":[217],"limit":[219],"unnecessary":[220],"exposure.":[221],"Awareness":[222],"could":[227],"prove":[228],"pivotal":[229],"success":[232],"future":[234],"preventive":[235],"strategies.":[236],"Initial":[237],"serum":[240],"levels":[242],"did":[243],"correlate":[245],"stay.":[249],"decision":[251],"facility":[257],"should":[258],"only":[259],"be":[260],"explored":[261],"once":[262],"patient":[264],"been":[266],"stabilised":[267],"Atropine":[270],"treatment":[271,285],"is":[272],"effective":[273],"but":[274],"carries":[275],"Glycopyrrolate":[280],"may":[281],"constitute":[282],"alternative":[284],"option.":[286]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":20},{"year":2021,"cited_by_count":4},{"year":2020,"cited_by_count":2},{"year":2019,"cited_by_count":23},{"year":2018,"cited_by_count":163},{"year":2017,"cited_by_count":109},{"year":2016,"cited_by_count":22},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":12},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":10}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}