{"id":"https://openalex.org/W1500817271","doi":null,"title":"Algorithms for computational genetic epidemiology","display_name":"Algorithms for computational genetic epidemiology","publication_year":2006,"publication_date":"2006-01-01","ids":{"openalex":"https://openalex.org/W1500817271","mag":"1500817271"},"language":"en","primary_location":{"id":"mag:1500817271","doi":null,"is_oa":false,"landing_page_url":"https://dl.acm.org/citation.cfm?id=1269371","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5072751459","display_name":"Alex Zelikovsky","orcid":"https://orcid.org/0000-0003-4424-4691","observed_orcids":["https://orcid.org/0000-0003-4424-4691"]},"institutions":[{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Alex Zelikovsky","raw_affiliation_strings":["Georgia State University,"],"raw_orcid":"https://orcid.org/0000-0003-4424-4691","affiliations":[{"raw_affiliation_string":"Georgia State University,","institution_ids":["https://openalex.org/I181565077"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5004407603","display_name":"Jingwu He","orcid":"https://orcid.org/0000-0002-2651-2317","observed_orcids":["https://orcid.org/0000-0002-2651-2317"]},"institutions":[{"id":"https://openalex.org/I181565077","display_name":"Georgia State University","ror":"https://ror.org/03qt6ba18","country_code":"US","type":"education","lineage":["https://openalex.org/I181565077"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jingwu He","raw_affiliation_strings":["Georgia State University,"],"raw_orcid":"https://orcid.org/0000-0002-2651-2317","affiliations":[{"raw_affiliation_string":"Georgia State University,","institution_ids":["https://openalex.org/I181565077"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I181565077"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.9916999936103821,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10751","display_name":"Forensic and Genetic Research","score":0.0027000000700354576,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11468","display_name":"Genetic Mapping and Diversity in Plants and Animals","score":0.0013000000035390258,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/haplotype-phasing","display_name":"haplotype phasing","score":0.8889999985694885},{"id":"https://openalex.org/keywords/haplotype-inference","display_name":"haplotype inference","score":0.9729999899864197},{"id":"https://openalex.org/keywords/single-nucleotide-polymorphisms","display_name":"single nucleotide polymorphisms","score":0.9179999828338623},{"id":"https://openalex.org/keywords/tag-snp-selection","display_name":"tag SNP selection","score":0.6600000262260437},{"id":"https://openalex.org/keywords/disease-association","display_name":"disease association","score":0.5680000185966492},{"id":"https://openalex.org/keywords/graph-based-methods","display_name":"graph-based methods","score":0.6800000071525574},{"id":"https://openalex.org/keywords/linear-programming","display_name":"linear programming","score":0.7440000176429749},{"id":"https://openalex.org/keywords/greedy-algorithm","display_name":"greedy algorithm","score":0.8640000224113464},{"id":"https://openalex.org/keywords/computational-complexity","display_name":"computational complexity","score":0.38199999928474426}],"concepts":[{"id":"https://openalex.org/C55060382","wikidata":"https://www.wikidata.org/wiki/Q7675093","display_name":"Tag SNP","level":5,"score":0.5998736619949341},{"id":"https://openalex.org/C153209595","wikidata":"https://www.wikidata.org/wiki/Q501128","display_name":"Single-nucleotide polymorphism","level":4,"score":0.5730114579200745},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.5027110576629639},{"id":"https://openalex.org/C163691529","wikidata":"https://www.wikidata.org/wiki/Q7391886","display_name":"SNP genotyping","level":5,"score":0.45891842246055603},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.4541168212890625},{"id":"https://openalex.org/C139275648","wikidata":"https://www.wikidata.org/wiki/Q17134011","display_name":"SNP","level":5,"score":0.421450674533844},{"id":"https://openalex.org/C186413461","wikidata":"https://www.wikidata.org/wiki/Q744727","display_name":"Genetic association","level":5,"score":0.42073673009872437},{"id":"https://openalex.org/C2776214188","wikidata":"https://www.wikidata.org/wiki/Q408386","display_name":"Inference","level":2,"score":0.415483295917511},{"id":"https://openalex.org/C31467283","wikidata":"https://www.wikidata.org/wiki/Q912147","display_name":"Genotyping","level":4,"score":0.412925660610199},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.3677034378051758},{"id":"https://openalex.org/C124101348","wikidata":"https://www.wikidata.org/wiki/Q172491","display_name":"Data mining","level":1,"score":0.3518867790699005},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3472011387348175},{"id":"https://openalex.org/C135763542","wikidata":"https://www.wikidata.org/wiki/Q106016","display_name":"Genotype","level":3,"score":0.29464191198349},{"id":"https://openalex.org/C154945302","wikidata":"https://www.wikidata.org/wiki/Q11660","display_name":"Artificial intelligence","level":1,"score":0.18133369088172913},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:1500817271","doi":null,"is_oa":false,"landing_page_url":"https://dl.acm.org/citation.cfm?id=1269371","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.428600013256073}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":72,"referenced_works":["https://openalex.org/W160412291","https://openalex.org/W1479694561","https://openalex.org/W1508985588","https://openalex.org/W1519521580","https://openalex.org/W1527532036","https://openalex.org/W1546828436","https://openalex.org/W1577092089","https://openalex.org/W1598648881","https://openalex.org/W1804762335","https://openalex.org/W1823969227","https://openalex.org/W1867257815","https://openalex.org/W1875901059","https://openalex.org/W1891919506","https://openalex.org/W1964901903","https://openalex.org/W1971771243","https://openalex.org/W1975676017","https://openalex.org/W1980175560","https://openalex.org/W1981232754","https://openalex.org/W1985849948","https://openalex.org/W1989681157","https://openalex.org/W1990390726","https://openalex.org/W1993494830","https://openalex.org/W1995945562","https://openalex.org/W2007006124","https://openalex.org/W2013892975","https://openalex.org/W2015408724","https://openalex.org/W2022005040","https://openalex.org/W2030327143","https://openalex.org/W2039237094","https://openalex.org/W2040615655","https://openalex.org/W2042413629","https://openalex.org/W2042441137","https://openalex.org/W2058401000","https://openalex.org/W2059543915","https://openalex.org/W2060268739","https://openalex.org/W2067455153","https://openalex.org/W2076744915","https://openalex.org/W2085406197","https://openalex.org/W2086370911","https://openalex.org/W2091062414","https://openalex.org/W2092450585","https://openalex.org/W2103647262","https://openalex.org/W2105257490","https://openalex.org/W2107349212","https://openalex.org/W2109342343","https://openalex.org/W2110755408","https://openalex.org/W2114335588","https://openalex.org/W2116794174","https://openalex.org/W2122227569","https://openalex.org/W2133610390","https://openalex.org/W2133712572","https://openalex.org/W2135732313","https://openalex.org/W2136204492","https://openalex.org/W2137321308","https://openalex.org/W2145838157","https://openalex.org/W2149512324","https://openalex.org/W2149796867","https://openalex.org/W2152664025","https://openalex.org/W2156179144","https://openalex.org/W2157249267","https://openalex.org/W2159267146","https://openalex.org/W2161351649","https://openalex.org/W2164628101","https://openalex.org/W2165792170","https://openalex.org/W2171359060","https://openalex.org/W2171792915","https://openalex.org/W2327088997","https://openalex.org/W2537403558","https://openalex.org/W2798153726","https://openalex.org/W4239510810","https://openalex.org/W4245892713","https://openalex.org/W7095201380"],"related_works":["https://openalex.org/W3135706862","https://openalex.org/W6955003779","https://openalex.org/W2248005775","https://openalex.org/W7207957789","https://openalex.org/W7101033897","https://openalex.org/W7097143819","https://openalex.org/W2767571853","https://openalex.org/W1525398553","https://openalex.org/W2143999835","https://openalex.org/W2056799531"],"abstract_inverted_index":{"The":[0,36,196],"most":[1],"intriguing":[2],"problems":[3,180],"in":[4,33,118,144],"genetics":[5],"epidemiology":[6],"are":[7,56],"to":[8,14,29,71,79,146,213],"predict":[9],"genetic":[10,34,142],"disease":[11,214,220,224],"susceptibility":[12,171],"and":[13,110,156,193,216,222],"associate":[15],"single":[16],"nucleotide":[17],"polymorphisms":[18],"(SNPs)":[19],"with":[20,181],"diseases.":[21,174],"In":[22],"such":[23],"these":[24],"studies,":[25],"it":[26,76,161],"is":[27,42,63,77,159,162],"necessary":[28],"resolve":[30],"the":[31,44,91,94,125,170],"ambiguities":[32],"data.":[35],"primary":[37],"obstacle":[38],"for":[39,47,138,219],"ambiguity":[40],"resolution":[41],"that":[43],"physical":[45],"methods":[46,167],"separating":[48],"two":[49],"haplotypes":[50],"from":[51],"an":[52],"individual":[53],"genotype":[54,150],"(phasing)":[55],"too":[57],"expensive.":[58],"Although":[59],"computational":[60,179],"haplotype":[61],"inference":[62],"a":[64,81,105,182],"well-explored":[65],"problem,":[66],"high":[67,119],"error":[68],"rates":[69],"continue":[70],"deteriorate":[72],"association":[73],"accuracy.":[74],"Secondly,":[75],"essential":[78],"use":[80],"small":[82],"subset":[83],"of":[84,93,108,127,134,140,172,184,201],"informative":[85,135],"SNPs":[86,95,109],"(tag":[87],"SNPs)":[88],"accurately":[89],"representing":[90],"rest":[92],"(tagging).":[96],"Tagging":[97],"can":[98,168],"achieve":[99],"budget":[100],"savings":[101],"by":[102],"genotyping":[103,121],"only":[104],"limited":[106],"number":[107],"computationally":[111],"inferring":[112],"all":[113],"other":[114],"SNPs.":[115],"Recent":[116],"successes":[117],"throughput":[120],"technologies":[122],"drastically":[123],"increase":[124],"length":[126],"available":[128],"SNP":[129,136],"sequences.":[130],"This":[131],"elevates":[132],"importance":[133],"selection":[137],"compaction":[139],"huge":[141],"data":[143,158],"order":[145],"make":[147],"feasible":[148],"fine":[149],"analysis.":[151],"Finally,":[152],"even":[153],"if":[154,164],"complete":[155],"accurate":[157],"available,":[160],"unclear":[163],"common":[165],"statistical":[166],"determine":[169],"complex":[173],"\r\nThe":[175],"dissertation":[176],"explores":[177],"above":[178],"variety":[183],"methods,":[185],"including":[186],"linear":[187,191],"algebra,":[188],"graph":[189],"theory,":[190],"programming,":[192],"greedy":[194],"methods.":[195],"contributions":[197],"include":[198],"(1)\u00a0significant":[199],"speed-up":[200],"popular":[202],"phasing":[203],"tools":[204,211],"without":[205],"compromising":[206],"their":[207],"quality,":[208],"(2)\u00a0stat-of-the-art":[209],"tagging":[210,221],"applied":[212],"association,":[215],"(3)\u00a0graph-based":[217],"method":[218],"predicting":[223],"susceptibility.":[225]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
