{"id":"https://openalex.org/W1499995259","doi":null,"title":"Ant\u00edgenos tumorales y desarrollo de vacunas contra el c\u00e1ncer utilizando p\u00e9ptidos antig\u00e9nicos","display_name":"Ant\u00edgenos tumorales y desarrollo de vacunas contra el c\u00e1ncer utilizando p\u00e9ptidos antig\u00e9nicos","publication_year":2013,"publication_date":"2013-03-12","ids":{"openalex":"https://openalex.org/W1499995259","mag":"1499995259"},"language":"es","primary_location":{"id":"mag:1499995259","doi":null,"is_oa":true,"landing_page_url":"https://biblat.unam.mx/es/revista/vertientes-mexico-d-f/articulo/antigenos-tumorales-y-desarrollo-de-vacunas-contra-el-cancer-utilizando-peptidos-antigenicos","pdf_url":null,"source":{"id":"https://openalex.org/S4306534154","display_name":"Vertientes. Revista Especializada en Ciencias de la Salud","issn_l":"1405-7867","issn":["1405-7867"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Vertientes. Revista Especializada en Ciencias de la Salud","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://biblat.unam.mx/es/revista/vertientes-mexico-d-f/articulo/antigenos-tumorales-y-desarrollo-de-vacunas-contra-el-cancer-utilizando-peptidos-antigenicos","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"Alberto Monroy","orcid":"https://orcid.org/0000-0002-9733-9013","observed_orcids":["https://orcid.org/0000-0002-9733-9013"]},"institutions":[{"id":"https://openalex.org/I8961855","display_name":"Universidad Nacional Aut\u00f3noma de M\u00e9xico","ror":"https://ror.org/01tmp8f25","country_code":"MX","type":"education","lineage":["https://openalex.org/I8961855"]}],"countries":["MX"],"is_corresponding":false,"raw_author_name":"Alberto Monroy","raw_affiliation_strings":["Universidad Nacional Aut\u00f3noma de M\u00e9xico, Facultad de Estudios Superiores Zaragoza, M\u00e9xico, Distrito Federal, M\u00e9xico"],"raw_orcid":"https://orcid.org/0000-0002-9733-9013","affiliations":[{"raw_affiliation_string":"Universidad Nacional Aut\u00f3noma de M\u00e9xico, Facultad de Estudios Superiores Zaragoza, M\u00e9xico, Distrito Federal, M\u00e9xico","institution_ids":["https://openalex.org/I8961855"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057006322","display_name":"Jorge Hern\u00e1ndez\u2010Montes","orcid":"https://orcid.org/0000-0003-0825-928X","observed_orcids":["https://orcid.org/0000-0003-0825-928X"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jorge Hern\u00e1ndez Montes","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5021663325","display_name":"Mar\u00eda de Lourdes Mora Garc\u00eda","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Mar\u00eda de Lourdes Mora Garc\u00eda","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.06124246,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"6","issue":"1","first_page":"26","last_page":"39"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10580","display_name":"Immunotherapy and Immune Responses","score":0.9994999766349792,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12576","display_name":"vaccines and immunoinformatics approaches","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10158","display_name":"Cancer Immunotherapy and Biomarkers","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/tumor-antigens","display_name":"tumor antigens","score":0.968999981880188},{"id":"https://openalex.org/keywords/cancer-vaccines","display_name":"cancer vaccines","score":0.9549999833106995},{"id":"https://openalex.org/keywords/antigenic-peptides","display_name":"antigenic peptides","score":0.8640000224113464},{"id":"https://openalex.org/keywords/tumor-associated-antigens","display_name":"tumor-associated antigens","score":0.718999981880188},{"id":"https://openalex.org/keywords/cd8-t-cells","display_name":"CD8+ T cells","score":0.652999997138977},{"id":"https://openalex.org/keywords/cd4-t-cells","display_name":"CD4+ T cells","score":0.9760000109672546},{"id":"https://openalex.org/keywords/testicular-antigens","display_name":"testicular antigens","score":0.7250000238418579},{"id":"https://openalex.org/keywords/differentiation-antigens","display_name":"differentiation antigens","score":0.7210000157356262},{"id":"https://openalex.org/keywords/her2-neu","display_name":"HER2/neu","score":0.9779999852180481},{"id":"https://openalex.org/keywords/hpv16-e7","display_name":"HPV16 E7","score":0.9290000200271606},{"id":"https://openalex.org/keywords/prostate-specific-membrane-antigen","display_name":"prostate-specific membrane antigen","score":0.8569999933242798},{"id":"https://openalex.org/keywords/carcinoembryonic-antigen","display_name":"carcinoembryonic antigen","score":0.9629999995231628},{"id":"https://openalex.org/keywords/muc1","display_name":"MUC1","score":0.9769999980926514},{"id":"https://openalex.org/keywords/kras","display_name":"KRAS","score":0.9860000014305115},{"id":"https://openalex.org/keywords/h-ras","display_name":"H-Ras","score":0.9769999980926514},{"id":"https://openalex.org/keywords/cancer-immunotherapy","display_name":"cancer immunotherapy","score":0.699999988079071},{"id":"https://openalex.org/keywords/prophylactic-vaccination","display_name":"prophylactic vaccination","score":0.7990000247955322}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.26751428842544556}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:1499995259","doi":null,"is_oa":true,"landing_page_url":"https://biblat.unam.mx/es/revista/vertientes-mexico-d-f/articulo/antigenos-tumorales-y-desarrollo-de-vacunas-contra-el-cancer-utilizando-peptidos-antigenicos","pdf_url":null,"source":{"id":"https://openalex.org/S4306534154","display_name":"Vertientes. Revista Especializada en Ciencias de la Salud","issn_l":"1405-7867","issn":["1405-7867"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Vertientes. Revista Especializada en Ciencias de la Salud","raw_type":null}],"best_oa_location":{"id":"mag:1499995259","doi":null,"is_oa":true,"landing_page_url":"https://biblat.unam.mx/es/revista/vertientes-mexico-d-f/articulo/antigenos-tumorales-y-desarrollo-de-vacunas-contra-el-cancer-utilizando-peptidos-antigenicos","pdf_url":null,"source":{"id":"https://openalex.org/S4306534154","display_name":"Vertientes. Revista Especializada en Ciencias de la Salud","issn_l":"1405-7867","issn":["1405-7867"],"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Vertientes. Revista Especializada en Ciencias de la Salud","raw_type":null},"sustainable_development_goals":[{"score":1.0,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":70,"referenced_works":["https://openalex.org/W33774928","https://openalex.org/W124736089","https://openalex.org/W601111552","https://openalex.org/W1445322489","https://openalex.org/W1509190187","https://openalex.org/W1558813989","https://openalex.org/W1579641819","https://openalex.org/W1815677039","https://openalex.org/W1946102895","https://openalex.org/W1965680142","https://openalex.org/W1972423862","https://openalex.org/W1974782765","https://openalex.org/W1979154086","https://openalex.org/W1982752226","https://openalex.org/W1987350137","https://openalex.org/W1988437817","https://openalex.org/W2002038445","https://openalex.org/W2003652884","https://openalex.org/W2005448550","https://openalex.org/W2005973682","https://openalex.org/W2007646169","https://openalex.org/W2010340952","https://openalex.org/W2010955189","https://openalex.org/W2014733698","https://openalex.org/W2016832628","https://openalex.org/W2017873985","https://openalex.org/W2029080338","https://openalex.org/W2029993034","https://openalex.org/W2031693363","https://openalex.org/W2033720551","https://openalex.org/W2035703380","https://openalex.org/W2038500217","https://openalex.org/W2043052307","https://openalex.org/W2044215567","https://openalex.org/W2047018074","https://openalex.org/W2053508680","https://openalex.org/W2060786724","https://openalex.org/W2064793974","https://openalex.org/W2068917085","https://openalex.org/W2072461945","https://openalex.org/W2073673847","https://openalex.org/W2074566129","https://openalex.org/W2080063940","https://openalex.org/W2080956086","https://openalex.org/W2083904539","https://openalex.org/W2084518949","https://openalex.org/W2085604990","https://openalex.org/W2092815945","https://openalex.org/W2094094710","https://openalex.org/W2095224412","https://openalex.org/W2095510701","https://openalex.org/W2096395857","https://openalex.org/W2096882514","https://openalex.org/W2098315731","https://openalex.org/W2106982482","https://openalex.org/W2107857115","https://openalex.org/W2118722884","https://openalex.org/W2125913713","https://openalex.org/W2126500509","https://openalex.org/W2127101164","https://openalex.org/W2131609927","https://openalex.org/W2136263976","https://openalex.org/W2141143434","https://openalex.org/W2143019738","https://openalex.org/W2149912943","https://openalex.org/W2151152262","https://openalex.org/W2159594827","https://openalex.org/W2172005924","https://openalex.org/W2412992458","https://openalex.org/W2464961741"],"related_works":["https://openalex.org/W2612415057","https://openalex.org/W7065649249","https://openalex.org/W2044215567","https://openalex.org/W2156728748","https://openalex.org/W7061166769","https://openalex.org/W1583507462","https://openalex.org/W7018460782","https://openalex.org/W2151592805","https://openalex.org/W2066392027","https://openalex.org/W1025211914"],"abstract_inverted_index":{"Menos":[0],"de":[1,4,42,62,84,94,99,120,139],"medio":[2],"centenar":[3],"genes":[5],"que":[6,28,100],"codifican":[7],"para":[8,112],"antigenos":[9,22,37,41,45],"asociados":[10],"a":[11,114],"tumores":[12,116,140],"malignos":[13],"en":[14,26,57,65,89,117,128],"humanos":[15],"han":[16,79],"sidoidentificados":[17],"hasta":[18],"nuestros":[19],"dias.":[20],"Los":[21],"tumorales":[23,46],"se":[24],"dividen":[25],"aquellos":[27],"son":[29],"reconocidos":[30],"ya":[31],"sea":[32],"por":[33],"linfocitosT":[34],"citotoxicos":[35],"CD8+:":[36],"testiculares":[38],"o":[39,48],"compartidos;":[40],"diferenciacion":[43],"y":[44,60,77],"mutados,":[47],"porlos":[49],"linfocitos":[50],"T":[51],"auxiliares":[52],"CD4+.":[53],"La":[54],"aplicacion":[55,102,127],"clinica":[56,103],"fase":[58],"I":[59],"II":[61],"vacunas":[63,129],"basadas":[64],"peptidos":[66],"antigenicos":[67],"derivados":[68],"deantigenos":[69],"como":[70],"HER-2/neu,":[71],"HPV16-E7,":[72],"PSMA,":[73],"CEA,":[74],"MUC-1,":[75],"K-ras":[76],"H-ras,":[78],"mostrado":[80],"tener":[81],"la":[82,118],"capacidad":[83],"estimularla":[85],"respuesta":[86],"inmune":[87],"celular":[88],"pacientes":[90],"con":[91],"diferentes":[92],"tipos":[93],"cancer":[95,107],"avanzado.":[96],"A":[97],"pesar":[98],"su":[101,126],"enel":[104],"tratamiento":[105],"del":[106],"no":[108],"ha":[109],"sido":[110],"suficiente":[111],"erradicar":[113],"los":[115,121],"mayoria":[119],"casos,":[122],"existen":[123],"evidencias":[124],"deque":[125],"profilacticas":[130],"puede":[131],"ser":[132],"una":[133],"mejor":[134],"estrategia":[135],"contra":[136],"el":[137],"desarrollo":[138],"cancerosos":[141]},"counts_by_year":[],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2016-06-24T00:00:00"}