{"id":"https://openalex.org/W1497869727","doi":null,"title":"Treating acute \"no-reflow\" with intracoronary adenosine in 4 patients during percutaneous coronary intervention.","display_name":"Treating acute \"no-reflow\" with intracoronary adenosine in 4 patients during percutaneous coronary intervention.","publication_year":2008,"publication_date":"2008-01-01","ids":{"openalex":"https://openalex.org/W1497869727","mag":"1497869727","pmid":"https://pubmed.ncbi.nlm.nih.gov/19156238","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2607097"},"language":"en","primary_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2607097","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2607097","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tex Heart Inst J","raw_type":"Text"},"volume":null,"type":"article","indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2607097","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016150099","display_name":"Mervyn B. Forman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210095179","display_name":"Saint Joseph's Hospital","ror":"https://ror.org/00m72p590","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I132943300","https://openalex.org/I150468666","https://openalex.org/I4210095179"]},{"id":"https://openalex.org/I4210117921","display_name":"Saint Joseph\u2019s Translational Research Institute","ror":"https://ror.org/02esr1a07","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I4210117921"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Mervyn B Forman","raw_affiliation_strings":["Saint Joseph's Translational Research Institute, Saint Joseph's Hospital, Atlanta, Georgia 30342, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Saint Joseph's Translational Research Institute, Saint Joseph's Hospital, Atlanta, Georgia 30342, USA","institution_ids":["https://openalex.org/I4210095179","https://openalex.org/I4210117921"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5068359233","display_name":"Dongming Hou","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dongming Hou","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5005780035","display_name":"Edwin Kerry Jackson","orcid":"https://orcid.org/0000-0002-8101-6009","observed_orcids":["https://orcid.org/0000-0002-8101-6009"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Edwin K Jackson","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3512,"has_fulltext":false,"cited_by_count":13,"citation_normalized_percentile":{"value":0.66411506,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"35","issue":"4","first_page":"439","last_page":"46"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.8794000148773193,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10193","display_name":"Coronary Interventions and Diagnostics","score":0.8794000148773193,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10292","display_name":"Acute Myocardial Infarction Research","score":0.07020000368356705,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11064","display_name":"Antiplatelet Therapy and Cardiovascular Diseases","score":0.017500000074505806,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/no-reflow-phenomenon","display_name":"no-reflow phenomenon","score":0.9879999756813049},{"id":"https://openalex.org/keywords/adenosine","display_name":"adenosine","score":0.8370000123977661},{"id":"https://openalex.org/keywords/intracoronary-adenosine","display_name":"intracoronary adenosine","score":0.8479999899864197},{"id":"https://openalex.org/keywords/percutaneous-coronary-intervention-complications","display_name":"percutaneous coronary intervention complications","score":0.9610000252723694},{"id":"https://openalex.org/keywords/saphenous-vein-graft","display_name":"saphenous vein graft","score":0.8899999856948853},{"id":"https://openalex.org/keywords/timi-flow-grade","display_name":"TIMI flow","score":0.746999979019165},{"id":"https://openalex.org/keywords/myocardial-blush","display_name":"myocardial blush","score":0.7620000243186951},{"id":"https://openalex.org/keywords/tissue-perfusion","display_name":"tissue perfusion","score":0.6790000200271606}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9509094953536987},{"id":"https://openalex.org/C2778300992","wikidata":"https://www.wikidata.org/wiki/Q7045267","display_name":"No reflow phenomenon","level":4,"score":0.9194159507751465},{"id":"https://openalex.org/C2777995511","wikidata":"https://www.wikidata.org/wiki/Q2897649","display_name":"TIMI","level":4,"score":0.8062869310379028},{"id":"https://openalex.org/C2780400711","wikidata":"https://www.wikidata.org/wiki/Q2008344","display_name":"Percutaneous coronary intervention","level":3,"score":0.7491920590400696},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.6893290877342224},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6055065393447876},{"id":"https://openalex.org/C2776991684","wikidata":"https://www.wikidata.org/wiki/Q190012","display_name":"Adenosine","level":2,"score":0.603374183177948},{"id":"https://openalex.org/C146957229","wikidata":"https://www.wikidata.org/wiki/Q1266915","display_name":"Perfusion","level":2,"score":0.574510395526886},{"id":"https://openalex.org/C500558357","wikidata":"https://www.wikidata.org/wiki/Q12152","display_name":"Myocardial infarction","level":2,"score":0.5539261698722839},{"id":"https://openalex.org/C2779581417","wikidata":"https://www.wikidata.org/wiki/Q1931577","display_name":"Thrombolysis","level":3,"score":0.47036904096603394},{"id":"https://openalex.org/C2776157398","wikidata":"https://www.wikidata.org/wiki/Q497232","display_name":"Coronary circulation","level":3,"score":0.45274031162261963},{"id":"https://openalex.org/C2780813298","wikidata":"https://www.wikidata.org/wiki/Q2071287","display_name":"Percutaneous","level":2,"score":0.4398147761821747},{"id":"https://openalex.org/C2781267111","wikidata":"https://www.wikidata.org/wiki/Q652297","display_name":"Catheter","level":2,"score":0.4128755033016205},{"id":"https://openalex.org/C158846371","wikidata":"https://www.wikidata.org/wiki/Q1642137","display_name":"Blood flow","level":2,"score":0.2929448187351227},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.22283953428268433}],"mesh":[{"descriptor_ui":"D000208","descriptor_name":"Acute Disease","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000241","descriptor_name":"Adenosine","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D000241","descriptor_name":"Adenosine","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003324","descriptor_name":"Coronary Artery Disease","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D003326","descriptor_name":"Coronary Circulation","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D003331","descriptor_name":"Coronary Vessels","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006085","descriptor_name":"Graft Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006439","descriptor_name":"Hemodynamics","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010477","descriptor_name":"Perfusion","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014665","descriptor_name":"Vasodilator Agents","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":false},{"descriptor_ui":"D014665","descriptor_name":"Vasodilator Agents","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D015906","descriptor_name":"Angioplasty, Balloon, Coronary","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":true}],"locations_count":3,"locations":[{"id":"pmh:oai:pubmedcentral.nih.gov:2607097","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2607097","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tex Heart Inst J","raw_type":"Text"},{"id":"pmid:19156238","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19156238","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Texas Heart Institute journal","raw_type":"Case Reports"},{"id":"mag:1497869727","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/19156238","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:pubmedcentral.nih.gov:2607097","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2607097","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Tex Heart Inst J","raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9922999739646912,"display_name":"Good health and well-being"}],"sustainable_development_goals_aurora":[{"id":"https://metadata.un.org/sdg/3","score":0.8899999856948853,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":30,"referenced_works":["https://openalex.org/W51406211","https://openalex.org/W78037676","https://openalex.org/W1964874304","https://openalex.org/W1966937352","https://openalex.org/W1989556513","https://openalex.org/W1992334086","https://openalex.org/W1996959516","https://openalex.org/W2001194331","https://openalex.org/W2004451265","https://openalex.org/W2013800949","https://openalex.org/W2014111139","https://openalex.org/W2016735950","https://openalex.org/W2021926698","https://openalex.org/W2025430764","https://openalex.org/W2036024297","https://openalex.org/W2046200498","https://openalex.org/W2074131116","https://openalex.org/W2075723991","https://openalex.org/W2076446257","https://openalex.org/W2080941089","https://openalex.org/W2083009969","https://openalex.org/W2092416729","https://openalex.org/W2095244715","https://openalex.org/W2103949379","https://openalex.org/W2107867617","https://openalex.org/W2108082043","https://openalex.org/W2122571743","https://openalex.org/W2126109777","https://openalex.org/W2161231462","https://openalex.org/W2327567334"],"related_works":["https://openalex.org/W2095244715","https://openalex.org/W2367449058","https://openalex.org/W3011080274","https://openalex.org/W2096102521","https://openalex.org/W2357535284","https://openalex.org/W2099350151","https://openalex.org/W2775889981","https://openalex.org/W7100574437","https://openalex.org/W4386104716","https://openalex.org/W3011671109"],"abstract_inverted_index":{"Angiographic":[0],"evidence":[1],"of":[2,15,34,47,80,112,122],"impaired":[3],"tissue":[4],"perfusion,":[5,104],"known":[6],"as":[7],"the":[8,35,45,52,83,119,125,141],"\"no-reflow\"":[9],"phenomenon,":[10],"is":[11,20,27],"a":[12],"serious":[13],"complication":[14],"percutaneous":[16,57,130],"coronary":[17,58,63,131],"intervention-one":[18],"that":[19,31,37],"associated":[21],"with":[22],"increased":[23],"mortality":[24],"rates.":[25],"Adenosine":[26],"an":[28],"endogenous":[29],"nucleoside":[30],"attenuates":[32],"many":[33],"mechanisms":[36],"are":[38],"responsible":[39],"for":[40],"no-reflow.":[41],"Herein,":[42],"we":[43],"report":[44],"cases":[46],"4":[48,71],"patients":[49],"who":[50],"developed":[51],"no-reflow":[53,142],"phenomenon":[54],"after":[55],"elective":[56],"intervention":[59,132],"to":[60,107],"their":[61],"native":[62],"arteries":[64],"and":[65,73],"saphenous":[66],"vein":[67],"grafts.":[68],"In":[69,92,110],"all":[70],"patients,":[72],"without":[74],"adverse":[75],"effects,":[76],"small":[77],"bolus":[78],"doses":[79],"adenosine":[81,123],"through":[82],"guiding":[84],"catheter":[85],"improved":[86],"epicardial":[87],"perfusion--measured":[88],"by":[89,137],"either":[90],"Thrombolysis":[91],"Myocardial":[93],"Infarction":[94],"(TIMI)":[95],"flow":[96],"grade":[97],"or":[98,139],"corrected":[99],"TIMI":[100],"frame":[101],"count-and":[102],"tissue-level":[103],"graded":[105],"according":[106],"myocardial":[108],"blush.":[109],"view":[111],"adenosine's":[113],"extremely":[114],"short":[115],"half-life":[116],"in":[117],"blood,":[118],"continuous":[120],"administration":[121],"into":[124],"distal":[126],"vascular":[127],"bed":[128],"throughout":[129],"may":[133],"further":[134],"improve":[135],"outcomes":[136],"reversing":[138],"preventing":[140],"phenomenon.":[143]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2021,"cited_by_count":3},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}