{"id":"https://openalex.org/W1497863497","doi":"https://doi.org/10.1002/j.1460-2075.1992.tb05301.x","title":"Three\u2010dimensional structure of transketolase, a thiamine diphosphate dependent enzyme, at 2.5 A resolution.","display_name":"Three\u2010dimensional structure of transketolase, a thiamine diphosphate dependent enzyme, at 2.5 A resolution.","publication_year":1992,"publication_date":"1992-07-01","ids":{"openalex":"https://openalex.org/W1497863497","doi":"https://doi.org/10.1002/j.1460-2075.1992.tb05301.x","mag":"1497863497","pmid":"https://pubmed.ncbi.nlm.nih.gov/1628611","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/556711"},"language":"en","primary_location":{"id":"doi:10.1002/j.1460-2075.1992.tb05301.x","doi":"https://doi.org/10.1002/j.1460-2075.1992.tb05301.x","is_oa":true,"landing_page_url":"https://doi.org/10.1002/j.1460-2075.1992.tb05301.x","pdf_url":"https://www.embopress.org/doi/pdf/10.1002/j.1460-2075.1992.tb05301.x?download=true","source":{"id":"https://openalex.org/S127916151","display_name":"The EMBO Journal","issn_l":"0261-4189","issn":["0261-4189","1460-2075"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO Journal","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://www.embopress.org/doi/pdf/10.1002/j.1460-2075.1992.tb05301.x?download=true","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5053178273","display_name":"Ylva Lindqvist","orcid":"https://orcid.org/0000-0003-3162-8661","observed_orcids":["https://orcid.org/0000-0003-3162-8661"]},"institutions":[{"id":"https://openalex.org/I298625061","display_name":"Swedish University of Agricultural Sciences","ror":"https://ror.org/02yy8x990","country_code":"SE","type":"education","lineage":["https://openalex.org/I298625061"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"Y. Lindqvist","raw_affiliation_strings":["Department of Molecular Biology, Swedish University of Agricultural Sciences, Uppsala Biomedical Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Swedish University of Agricultural Sciences, Uppsala Biomedical Center","institution_ids":["https://openalex.org/I298625061"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5010549483","display_name":"Gunter Schneider","orcid":"https://orcid.org/0000-0003-0622-5713","observed_orcids":["https://orcid.org/0000-0003-0622-5713"]},"institutions":[{"id":"https://openalex.org/I298625061","display_name":"Swedish University of Agricultural Sciences","ror":"https://ror.org/02yy8x990","country_code":"SE","type":"education","lineage":["https://openalex.org/I298625061"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"G. Schneider","raw_affiliation_strings":["Department of Molecular Biology, Swedish University of Agricultural Sciences, Uppsala Biomedical Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Swedish University of Agricultural Sciences, Uppsala Biomedical Center","institution_ids":["https://openalex.org/I298625061"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5071428495","display_name":"Ulrich Ermler","orcid":"https://orcid.org/0000-0002-9583-1418","observed_orcids":["https://orcid.org/0000-0002-9583-1418","https://orcid.org/0000-0001-7190-0434"]},"institutions":[{"id":"https://openalex.org/I298625061","display_name":"Swedish University of Agricultural Sciences","ror":"https://ror.org/02yy8x990","country_code":"SE","type":"education","lineage":["https://openalex.org/I298625061"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"U. Ermler","raw_affiliation_strings":["Department of Molecular Biology, Swedish University of Agricultural Sciences, Uppsala Biomedical Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Swedish University of Agricultural Sciences, Uppsala Biomedical Center","institution_ids":["https://openalex.org/I298625061"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010007630","display_name":"M. Sundstr\u00f6m","orcid":"https://orcid.org/0009-0000-4972-5481","observed_orcids":["https://orcid.org/0009-0000-4972-5481"]},"institutions":[{"id":"https://openalex.org/I298625061","display_name":"Swedish University of Agricultural Sciences","ror":"https://ror.org/02yy8x990","country_code":"SE","type":"education","lineage":["https://openalex.org/I298625061"]}],"countries":["SE"],"is_corresponding":false,"raw_author_name":"M. Sundstr\u00f6m","raw_affiliation_strings":["Department of Molecular Biology, Swedish University of Agricultural Sciences, Uppsala Biomedical Center"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular Biology, Swedish University of Agricultural Sciences, Uppsala Biomedical Center","institution_ids":["https://openalex.org/I298625061"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I298625061"],"apc_list":{"value":7990,"currency":"USD","value_usd":7990},"apc_paid":null,"fwci":6.6765,"has_fulltext":true,"cited_by_count":365,"citation_normalized_percentile":{"value":0.98407432,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":95,"max":100},"biblio":{"volume":"11","issue":"7","first_page":"2373","last_page":"2379"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12915","display_name":"Biochemical Acid Research Studies","score":0.611299991607666,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12915","display_name":"Biochemical Acid Research Studies","score":0.611299991607666,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11162","display_name":"Enzyme Structure and Function","score":0.38350000977516174,"subfield":{"id":"https://openalex.org/subfields/1315","display_name":"Structural Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10044","display_name":"Protein Structure and Dynamics","score":0.0019000000320374966,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/transketolase","display_name":"transketolase","score":0.9990000128746033},{"id":"https://openalex.org/keywords/thiamine-pyrophosphate","display_name":"thiamine pyrophosphate","score":0.9350000023841858},{"id":"https://openalex.org/keywords/thiamine-dependent-enzymes","display_name":"thiamine-dependent enzymes","score":0.7229999899864197},{"id":"https://openalex.org/keywords/saccharomyces-cerevisiae","display_name":"Saccharomyces cerevisiae","score":0.9179999828338623},{"id":"https://openalex.org/keywords/enzyme-dimer","display_name":"enzyme dimer","score":0.6269999742507935},{"id":"https://openalex.org/keywords/cofactor-binding","display_name":"cofactor binding","score":0.8529999852180481},{"id":"https://openalex.org/keywords/calcium-binding","display_name":"calcium binding","score":0.5690000057220459},{"id":"https://openalex.org/keywords/alpha-beta-domain","display_name":"alpha/beta domain","score":0.9100000262260437},{"id":"https://openalex.org/keywords/enzyme-active-site","display_name":"enzyme active site","score":0.5540000200271606},{"id":"https://openalex.org/keywords/pyrimidine-ring","display_name":"pyrimidine ring","score":0.47699999809265137},{"id":"https://openalex.org/keywords/hydrophobic-pocket","display_name":"hydrophobic pocket","score":0.6959999799728394}],"concepts":[{"id":"https://openalex.org/C103432212","wikidata":"https://www.wikidata.org/wiki/Q412719","display_name":"Transketolase","level":3,"score":0.9661157131195068},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8463087677955627},{"id":"https://openalex.org/C2776203871","wikidata":"https://www.wikidata.org/wiki/Q83187","display_name":"Thiamine","level":2,"score":0.7705037593841553},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.6312835812568665},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.59550541639328},{"id":"https://openalex.org/C2780047943","wikidata":"https://www.wikidata.org/wiki/Q415003","display_name":"Thiamine pyrophosphate","level":4,"score":0.47366437315940857},{"id":"https://openalex.org/C197957613","wikidata":"https://www.wikidata.org/wiki/Q407280","display_name":"Cofactor","level":3,"score":0.20937290787696838}],"mesh":[{"descriptor_ui":"D001665","descriptor_name":"Binding Sites","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003198","descriptor_name":"Computer Simulation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011487","descriptor_name":"Protein Conformation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012441","descriptor_name":"Saccharomyces cerevisiae","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D013835","descriptor_name":"Thiamine Pyrophosphate","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D014174","descriptor_name":"Transketolase","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014174","descriptor_name":"Transketolase","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D014961","descriptor_name":"X-Ray Diffraction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1002/j.1460-2075.1992.tb05301.x","doi":"https://doi.org/10.1002/j.1460-2075.1992.tb05301.x","is_oa":true,"landing_page_url":"https://doi.org/10.1002/j.1460-2075.1992.tb05301.x","pdf_url":"https://www.embopress.org/doi/pdf/10.1002/j.1460-2075.1992.tb05301.x?download=true","source":{"id":"https://openalex.org/S127916151","display_name":"The EMBO Journal","issn_l":"0261-4189","issn":["0261-4189","1460-2075"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO Journal","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:224172","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC556711","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:556711","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/556711","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"EMBO J","raw_type":"Text"},{"id":"pmid:1628611","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1628611","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO journal","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1002/j.1460-2075.1992.tb05301.x","doi":"https://doi.org/10.1002/j.1460-2075.1992.tb05301.x","is_oa":true,"landing_page_url":"https://doi.org/10.1002/j.1460-2075.1992.tb05301.x","pdf_url":"https://www.embopress.org/doi/pdf/10.1002/j.1460-2075.1992.tb05301.x?download=true","source":{"id":"https://openalex.org/S127916151","display_name":"The EMBO Journal","issn_l":"0261-4189","issn":["0261-4189","1460-2075"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-3","ki-jl-3","medline","norway-2","oarl","poland-200","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The EMBO Journal","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320322581","display_name":"Vetenskapsr\u00e5det","ror":"https://ror.org/03zttf063"},{"id":"https://openalex.org/F4320323741","display_name":"Magnus Bergvalls Stiftelse","ror":"https://ror.org/040ya8k73"}],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1497863497.pdf","grobid_xml":"https://content.openalex.org/works/W1497863497.grobid-xml"},"referenced_works_count":19,"referenced_works":["https://openalex.org/W79362862","https://openalex.org/W135160761","https://openalex.org/W1499335874","https://openalex.org/W1557525759","https://openalex.org/W1557657530","https://openalex.org/W1606011614","https://openalex.org/W1977488321","https://openalex.org/W1984670390","https://openalex.org/W1994303513","https://openalex.org/W1995812274","https://openalex.org/W1996726147","https://openalex.org/W2001595933","https://openalex.org/W2013083986","https://openalex.org/W2056402927","https://openalex.org/W2060728728","https://openalex.org/W2068441466","https://openalex.org/W2075521810","https://openalex.org/W6600651459","https://openalex.org/W6629771334"],"related_works":["https://openalex.org/W1976773992","https://openalex.org/W2066424538","https://openalex.org/W4254043210","https://openalex.org/W1971308409","https://openalex.org/W1981159588","https://openalex.org/W2050970795","https://openalex.org/W2034371095","https://openalex.org/W2132886727","https://openalex.org/W252948261","https://openalex.org/W2040509024"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":8},{"year":2024,"cited_by_count":10},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":4},{"year":2021,"cited_by_count":7},{"year":2020,"cited_by_count":7},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":3},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":11},{"year":2013,"cited_by_count":17},{"year":2012,"cited_by_count":10}],"updated_date":"2026-11-07T11:25:07.637180","created_date":"2016-06-24T00:00:00"}