{"id":"https://openalex.org/W1495348463","doi":"https://doi.org/10.1111/j.1365-313x.2005.02374.x","title":"Multiplicity of different cell\u2010 and organ\u2010specific import routes for the NADPH\u2010protochlorophyllide oxidoreductases A and B in plastids of Arabidopsis seedlings","display_name":"Multiplicity of different cell\u2010 and organ\u2010specific import routes for the NADPH\u2010protochlorophyllide oxidoreductases A and B in plastids of Arabidopsis seedlings","publication_year":2005,"publication_date":"2005-02-28","ids":{"openalex":"https://openalex.org/W1495348463","doi":"https://doi.org/10.1111/j.1365-313x.2005.02374.x","mag":"1495348463","pmid":"https://pubmed.ncbi.nlm.nih.gov/15842619"},"language":"en","primary_location":{"id":"doi:10.1111/j.1365-313x.2005.02374.x","doi":"https://doi.org/10.1111/j.1365-313x.2005.02374.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1365-313x.2005.02374.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-313X.2005.02374.x","source":{"id":"https://openalex.org/S67862205","display_name":"The Plant Journal","issn_l":"0960-7412","issn":["0960-7412","1365-313X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Plant Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-313X.2005.02374.x","any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5088108746","display_name":"Chanhong Kim","orcid":"https://orcid.org/0000-0003-4133-9070","observed_orcids":["https://orcid.org/0000-0003-4133-9070"]},"institutions":[{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]}],"countries":["CH"],"is_corresponding":false,"raw_author_name":"Chanhong Kim","raw_affiliation_strings":["Institute of Plant Sciences, Plant Genetics, Swiss Federal Institute of Technology (ETH), CH-8092, Zurich, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Institute of Plant Sciences, Plant Genetics, Swiss Federal Institute of Technology (ETH), CH-8092, Zurich, Switzerland","institution_ids":["https://openalex.org/I35440088"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032616537","display_name":"Hyemin Ham","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I123900574","display_name":"Pohang University of Science and Technology","ror":"https://ror.org/04xysgw12","country_code":"KR","type":"education","lineage":["https://openalex.org/I123900574"]},{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]}],"countries":["CH","KR"],"is_corresponding":false,"raw_author_name":"Hyemin Ham","raw_affiliation_strings":["Present address: Department of Life Science, Pohang University of Science and Technology, Korea","Institute of Plant Sciences, Plant Genetics, Swiss Federal Institute of Technology (ETH), CH\u20108092, Zurich, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Present address: Department of Life Science, Pohang University of Science and Technology, Korea","institution_ids":["https://openalex.org/I123900574"]},{"raw_affiliation_string":"Institute of Plant Sciences, Plant Genetics, Swiss Federal Institute of Technology (ETH), CH\u20108092, Zurich, Switzerland","institution_ids":["https://openalex.org/I35440088"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5070687867","display_name":"Klaus Apel","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I123900574","display_name":"Pohang University of Science and Technology","ror":"https://ror.org/04xysgw12","country_code":"KR","type":"education","lineage":["https://openalex.org/I123900574"]},{"id":"https://openalex.org/I35440088","display_name":"ETH Zurich","ror":"https://ror.org/05a28rw58","country_code":"CH","type":"education","lineage":["https://openalex.org/I2799323385","https://openalex.org/I35440088"]}],"countries":["CH","KR"],"is_corresponding":true,"raw_author_name":"Klaus Apel","raw_affiliation_strings":["Department of Life Science , Pohang University of Science and Technology , Korea","Institute of Plant Sciences, Plant Genetics, Swiss Federal Institute of Technology (ETH), CH\u20108092, Zurich, Switzerland"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Life Science , Pohang University of Science and Technology , Korea","institution_ids":["https://openalex.org/I123900574"]},{"raw_affiliation_string":"Institute of Plant Sciences, Plant Genetics, Swiss Federal Institute of Technology (ETH), CH\u20108092, Zurich, Switzerland","institution_ids":["https://openalex.org/I35440088"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5070687867"],"corresponding_institution_ids":["https://openalex.org/I123900574","https://openalex.org/I35440088"],"apc_list":{"value":5450,"currency":"USD","value_usd":5450},"apc_paid":null,"fwci":1.3993,"has_fulltext":true,"cited_by_count":27,"citation_normalized_percentile":{"value":0.77572993,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"42","issue":"3","first_page":"329","last_page":"340"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10303","display_name":"Photosynthetic Processes and Mechanisms","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10303","display_name":"Photosynthetic Processes and Mechanisms","score":0.9937000274658203,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11268","display_name":"Light effects on plants","score":0.0017999999690800905,"subfield":{"id":"https://openalex.org/subfields/1110","display_name":"Plant Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11882","display_name":"Plant biochemistry and biosynthesis","score":0.0010999999940395355,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/nadph-protochlorophyllide-oxidoreductase","display_name":"NADPH:protochlorophyllide oxidoreductase","score":0.9300000071525574},{"id":"https://openalex.org/keywords/pora","display_name":"PorA","score":0.8080000281333923},{"id":"https://openalex.org/keywords/porb","display_name":"PorB","score":1.0},{"id":"https://openalex.org/keywords/plastid-protein-import","display_name":"plastid protein import","score":0.9190000295639038},{"id":"https://openalex.org/keywords/toc159","display_name":"Toc159","score":0.9129999876022339},{"id":"https://openalex.org/keywords/toc34","display_name":"Toc34","score":0.9869999885559082},{"id":"https://openalex.org/keywords/cotyledons","display_name":"cotyledons","score":0.7089999914169312},{"id":"https://openalex.org/keywords/arabidopsis-thaliana-seedlings","display_name":"Arabidopsis thaliana seedlings","score":0.8569999933242798},{"id":"https://openalex.org/keywords/nuclear-encoded-plastid-proteins","display_name":"nuclear-encoded plastid proteins","score":0.800000011920929},{"id":"https://openalex.org/keywords/chlorophyll-biosynthesis","display_name":"chlorophyll biosynthesis","score":0.8190000057220459}],"concepts":[{"id":"https://openalex.org/C93829228","wikidata":"https://www.wikidata.org/wiki/Q165963","display_name":"Plastid","level":4,"score":0.9144080877304077},{"id":"https://openalex.org/C2779520027","wikidata":"https://www.wikidata.org/wiki/Q211118","display_name":"Protochlorophyllide","level":4,"score":0.7594394087791443},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.746979296207428},{"id":"https://openalex.org/C2779491563","wikidata":"https://www.wikidata.org/wiki/Q157892","display_name":"Arabidopsis","level":4,"score":0.6869531869888306},{"id":"https://openalex.org/C131934819","wikidata":"https://www.wikidata.org/wiki/Q135390","display_name":"Biogenesis","level":3,"score":0.609920859336853},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.5334855318069458},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.4023990035057068},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.35673287510871887},{"id":"https://openalex.org/C553450214","wikidata":"https://www.wikidata.org/wiki/Q851162","display_name":"Biosynthesis","level":3,"score":0.2761285901069641},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.2647799551486969},{"id":"https://openalex.org/C69305403","wikidata":"https://www.wikidata.org/wiki/Q47263","display_name":"Chloroplast","level":3,"score":0.16082561016082764}],"mesh":[{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D017360","descriptor_name":"Arabidopsis","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D018087","descriptor_name":"Plastids","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D018548","descriptor_name":"Cotyledon","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018548","descriptor_name":"Cotyledon","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D021381","descriptor_name":"Protein Transport","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D029681","descriptor_name":"Arabidopsis Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D030821","descriptor_name":"Plants, Genetically Modified","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D036226","descriptor_name":"Seedlings","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":true},{"descriptor_ui":"D036226","descriptor_name":"Seedlings","qualifier_ui":"Q000648","qualifier_name":"ultrastructure","is_major_topic":false},{"descriptor_ui":"D044925","descriptor_name":"Oxidoreductases Acting on CH-CH Group Donors","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1111/j.1365-313x.2005.02374.x","doi":"https://doi.org/10.1111/j.1365-313x.2005.02374.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1365-313x.2005.02374.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-313X.2005.02374.x","source":{"id":"https://openalex.org/S67862205","display_name":"The Plant Journal","issn_l":"0960-7412","issn":["0960-7412","1365-313X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Plant Journal","raw_type":"journal-article"},{"id":"pmid:15842619","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15842619","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Plant journal : for cell and molecular biology","raw_type":"Journal Article"}],"best_oa_location":{"id":"doi:10.1111/j.1365-313x.2005.02374.x","doi":"https://doi.org/10.1111/j.1365-313x.2005.02374.x","is_oa":true,"landing_page_url":"https://doi.org/10.1111/j.1365-313x.2005.02374.x","pdf_url":"https://onlinelibrary.wiley.com/doi/pdfdirect/10.1111/j.1365-313X.2005.02374.x","source":{"id":"https://openalex.org/S67862205","display_name":"The Plant Journal","issn_l":"0960-7412","issn":["0960-7412","1365-313X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-a","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Plant Journal","raw_type":"journal-article"},"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320307786","display_name":"Adobe Systems","ror":"https://ror.org/059tvcg64"},{"id":"https://openalex.org/F4320320924","display_name":"Schweizerischer Nationalfonds zur F\u00f6rderung der Wissenschaftlichen Forschung","ror":"https://ror.org/00yjd3n13"},{"id":"https://openalex.org/F4320321652","display_name":"Eidgen\u00f6ssische Technische Hochschule Z\u00fcrich","ror":"https://ror.org/05a28rw58"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1495348463.pdf","grobid_xml":"https://content.openalex.org/works/W1495348463.grobid-xml"},"referenced_works_count":46,"referenced_works":["https://openalex.org/W104110300","https://openalex.org/W1551620788","https://openalex.org/W1564544391","https://openalex.org/W1656671666","https://openalex.org/W1665473358","https://openalex.org/W1676597590","https://openalex.org/W1964706895","https://openalex.org/W1965818607","https://openalex.org/W1969472583","https://openalex.org/W1971444391","https://openalex.org/W1973471150","https://openalex.org/W1974256119","https://openalex.org/W1983723489","https://openalex.org/W2010677294","https://openalex.org/W2016052440","https://openalex.org/W2017476232","https://openalex.org/W2023030898","https://openalex.org/W2026869893","https://openalex.org/W2033560852","https://openalex.org/W2046446960","https://openalex.org/W2047158635","https://openalex.org/W2059426360","https://openalex.org/W2064115640","https://openalex.org/W2068609041","https://openalex.org/W2077264930","https://openalex.org/W2091190306","https://openalex.org/W2096615860","https://openalex.org/W2099995178","https://openalex.org/W2101359280","https://openalex.org/W2103422734","https://openalex.org/W2111900922","https://openalex.org/W2111976416","https://openalex.org/W2117213630","https://openalex.org/W2117335544","https://openalex.org/W2118472374","https://openalex.org/W2118983234","https://openalex.org/W2122772605","https://openalex.org/W2126064799","https://openalex.org/W2131948277","https://openalex.org/W2132149094","https://openalex.org/W2133757350","https://openalex.org/W2138965000","https://openalex.org/W2148721211","https://openalex.org/W2161642448","https://openalex.org/W2169146256","https://openalex.org/W4255993837"],"related_works":["https://openalex.org/W2169146256","https://openalex.org/W2140754470","https://openalex.org/W2010677294","https://openalex.org/W1564544391","https://openalex.org/W1960112293","https://openalex.org/W2131948277","https://openalex.org/W1996575008","https://openalex.org/W2094354926","https://openalex.org/W2033560852","https://openalex.org/W1574243523"],"abstract_inverted_index":{"The":[0,34,89,214],"NADPH-dependent":[1],"protochlorophyllide":[2],"(Pchlide)":[3],"oxidoreductase":[4],"(POR)":[5],"is":[6,58,169,183],"a":[7,21,154],"photoenzyme":[8],"that":[9,80,148,196,233,253],"requires":[10],"light":[11],"for":[12,83,171,185,247],"its":[13],"catalytic":[14],"activity":[15],"and":[16,32,36,60,70,103,111,125,140,146,160,176,192,206,218,240],"uses":[17],"Pchlide":[18],"itself":[19],"as":[20],"photoreceptor.":[22],"In":[23,46],"Arabidopsis":[24,135],"there":[25],"are":[26,39,74,81,149,272],"three":[27,142,166],"PORs":[28],"denoted":[29],"PORA,":[30],"PORB":[31,37,49,71,189,207,219],"PORC.":[33],"PORA":[35,53,69,129,180,205,217],"genes":[38],"strongly":[40],"expressed":[41],"early":[42],"in":[43,64,108,121,133,151,190,197,254,274],"seedling":[44],"development.":[45],"contrast":[47],"to":[48,76,250],"the":[50,65,84,95,98,109,141,173,186,201,259,262,276],"import":[51,66,78,130,187,212,220,231,266,277],"of":[52,56,86,94,97,113,115,128,137,158,164,179,188,200,204,216,223,230,245,261,265,278],"into":[54,221],"plastids":[55,222,251],"cotyledons":[57,191],"substrate-dependent":[59],"organ-specific.":[61],"These":[62],"differences":[63],"reactions":[67],"between":[68],"most":[72],"likely":[73],"due":[75],"different":[77],"mechanisms":[79],"responsible":[82],"uptake":[85],"these":[87,165,198],"proteins.":[88,118,281],"two":[90,210],"major":[91],"core":[92,263],"constituents":[93,168,260],"translocon":[96],"outer":[99],"plastid":[100,117,280],"envelope,":[101],"Toc159":[102],"Toc34,":[104],"have":[105],"been":[106],"implicated":[107],"binding":[110],"recognition":[112],"precursors":[114],"nuclear-encoded":[116,279],"Their":[119],"involvement":[120],"conferring":[122],"substrate":[123,177],"dependency":[124,178],"organ":[126,174,241],"specificity":[127,175],"was":[131],"analyzed":[132],"intact":[134,224,255],"seedlings":[136,225,256],"wild":[138],"type":[139],"mutants":[143],"ppi3,":[144],"ppi1":[145],"ppi2":[147],"deficient":[150],"atToc34,":[152,159],"atToc33,":[153],"closely":[155],"related":[156],"isoform":[157],"atToc159.":[161],"Whereas":[162],"none":[163],"Toc":[167],"required":[170],"maintaining":[172],"import,":[181],"atToc33":[182],"indispensable":[184],"true":[193],"leaves":[194],"suggesting":[195],"parts":[199],"plant":[202],"translocation":[203],"occurs":[208],"via":[209],"distinct":[211],"pathways.":[213],"analysis":[215],"revealed":[226],"an":[227],"unexpected":[228],"multiplicity":[229],"routes":[232],"differed":[234],"by":[235],"their":[236],"substrate,":[237],"cell,":[238],"tissue":[239],"specificities.":[242],"This":[243],"versatility":[244],"pathways":[246],"protein":[248],"targeting":[249],"suggests":[252],"not":[257],"only":[258],"complex":[264],"channels":[267],"but":[268],"also":[269],"other":[270],"factors":[271],"involved":[273],"mediating":[275]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}