{"id":"https://openalex.org/W1494052425","doi":"https://doi.org/10.1046/j.1464-410x.2002.02810.x","title":"Modulation of heat\u2010induced cell death in PC\u20103 prostate cancer cells by the antioxidant inhibitor diethyldithiocarbamate","display_name":"Modulation of heat\u2010induced cell death in PC\u20103 prostate cancer cells by the antioxidant inhibitor diethyldithiocarbamate","publication_year":2002,"publication_date":"2002-07-19","ids":{"openalex":"https://openalex.org/W1494052425","doi":"https://doi.org/10.1046/j.1464-410x.2002.02810.x","mag":"1494052425","pmid":"https://pubmed.ncbi.nlm.nih.gov/12133072"},"language":"en","primary_location":{"id":"doi:10.1046/j.1464-410x.2002.02810.x","doi":"https://doi.org/10.1046/j.1464-410x.2002.02810.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.1464-410x.2002.02810.x","pdf_url":null,"source":{"id":"https://openalex.org/S191188855","display_name":"British Journal of Urology","issn_l":"1464-4096","issn":["1464-4096","1464-410X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BJU International","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5060140916","display_name":"Nobuko Moriyama\u2010Gonda","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285000","display_name":"Shimane Medical University","ror":"https://ror.org/04kg5pk90","country_code":"JP","type":"education","lineage":["https://openalex.org/I169016828","https://openalex.org/I4405285000"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"N. Moriyama\u2010Gonda","raw_affiliation_strings":["Department of Urology, Shimane Medical University, Izumo, Japan. gonada-n@shimane-med.ac.jp","Departments of Urology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Urology, Shimane Medical University, Izumo, Japan. gonada-n@shimane-med.ac.jp","institution_ids":["https://openalex.org/I4405285000"]},{"raw_affiliation_string":"Departments of Urology and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036097429","display_name":"Mikio Igawa","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M. Igawa","raw_affiliation_strings":["Departments of Urology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Urology and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058077375","display_name":"Hiroaki Shiina","orcid":"https://orcid.org/0000-0002-8959-1817","observed_orcids":["https://orcid.org/0000-0002-8959-1817"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"H. Shiina","raw_affiliation_strings":["Departments of Urology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Urology and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5088906257","display_name":"Shinji Urakami","orcid":"https://orcid.org/0000-0003-3753-9950","observed_orcids":["https://orcid.org/0000-0003-3753-9950"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"S. Urakami","raw_affiliation_strings":["Departments of Urology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Urology and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111425568","display_name":"K. Shigeno","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K. Shigeno","raw_affiliation_strings":["Departments of Urology and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Departments of Urology and","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5036310564","display_name":"Masaharu Terashima","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4405285000","display_name":"Shimane Medical University","ror":"https://ror.org/04kg5pk90","country_code":"JP","type":"education","lineage":["https://openalex.org/I169016828","https://openalex.org/I4405285000"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"M. Terashima","raw_affiliation_strings":["Biochemistry, Shimane Medical University, Izumo, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biochemistry, Shimane Medical University, Izumo, Japan","institution_ids":["https://openalex.org/I4405285000"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":4770,"currency":"USD","value_usd":4770},"apc_paid":null,"fwci":0.2868,"has_fulltext":false,"cited_by_count":29,"citation_normalized_percentile":{"value":0.46238063,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"90","issue":"3","first_page":"317","last_page":"325"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":0.3792000114917755,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10934","display_name":"Heat shock proteins research","score":0.3792000114917755,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10294","display_name":"Cell death mechanisms and regulation","score":0.22990000247955322,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10958","display_name":"Ultrasound and Hyperthermia Applications","score":0.15160000324249268,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heat-induced-cell-death","display_name":"heat-induced cell death","score":0.8029999732971191},{"id":"https://openalex.org/keywords/pc-3-cells","display_name":"PC-3 cells","score":0.8539999723434448},{"id":"https://openalex.org/keywords/diethyldithiocarbamate","display_name":"diethyldithiocarbamate","score":0.9520000219345093},{"id":"https://openalex.org/keywords/thermotherapy","display_name":"heat therapy","score":0.871999979019165},{"id":"https://openalex.org/keywords/apoptosis","display_name":"apoptosis","score":0.5809999704360962},{"id":"https://openalex.org/keywords/necrosis","display_name":"necrosis","score":0.996999979019165},{"id":"https://openalex.org/keywords/reactive-oxygen-species","display_name":"reactive oxygen species","score":0.9860000014305115},{"id":"https://openalex.org/keywords/superoxide-dismutase","display_name":"superoxide dismutase","score":0.9990000128746033},{"id":"https://openalex.org/keywords/hsp70","display_name":"HSP70","score":0.9539999961853027},{"id":"https://openalex.org/keywords/antioxidant-therapy","display_name":"antioxidant therapy","score":0.6389999985694885},{"id":"https://openalex.org/keywords/cell-proliferation-inhibition","display_name":"cell proliferation inhibition","score":0.4790000021457672},{"id":"https://openalex.org/keywords/oxidative-stress","display_name":"oxidative stress","score":0.4909999966621399}],"concepts":[{"id":"https://openalex.org/C2775934118","wikidata":"https://www.wikidata.org/wiki/Q424169","display_name":"Propidium iodide","level":4,"score":0.8665936589241028},{"id":"https://openalex.org/C190283241","wikidata":"https://www.wikidata.org/wiki/Q14599311","display_name":"Apoptosis","level":2,"score":0.6714440584182739},{"id":"https://openalex.org/C2779964046","wikidata":"https://www.wikidata.org/wiki/Q209286","display_name":"Dichlorofluorescein","level":3,"score":0.635486900806427},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.6293522119522095},{"id":"https://openalex.org/C88634738","wikidata":"https://www.wikidata.org/wiki/Q24769543","display_name":"Annexin","level":3,"score":0.6185113191604614},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5610139966011047},{"id":"https://openalex.org/C2775838275","wikidata":"https://www.wikidata.org/wiki/Q410776","display_name":"Superoxide dismutase","level":3,"score":0.5535172820091248},{"id":"https://openalex.org/C553184892","wikidata":"https://www.wikidata.org/wiki/Q1141429","display_name":"Flow cytometry","level":2,"score":0.5250325202941895},{"id":"https://openalex.org/C503630168","wikidata":"https://www.wikidata.org/wiki/Q178069","display_name":"Necrosis","level":2,"score":0.5213069319725037},{"id":"https://openalex.org/C48349386","wikidata":"https://www.wikidata.org/wiki/Q424361","display_name":"Reactive oxygen species","level":2,"score":0.47121018171310425},{"id":"https://openalex.org/C31573885","wikidata":"https://www.wikidata.org/wiki/Q304484","display_name":"Programmed cell death","level":3,"score":0.44893842935562134},{"id":"https://openalex.org/C2779949491","wikidata":"https://www.wikidata.org/wiki/Q242165","display_name":"Hyperthermia","level":2,"score":0.43200838565826416},{"id":"https://openalex.org/C68991219","wikidata":"https://www.wikidata.org/wiki/Q419102","display_name":"Hsp70","level":4,"score":0.41014957427978516},{"id":"https://openalex.org/C205260736","wikidata":"https://www.wikidata.org/wiki/Q418939","display_name":"Heat shock protein","level":3,"score":0.34910160303115845},{"id":"https://openalex.org/C2778004101","wikidata":"https://www.wikidata.org/wiki/Q133948","display_name":"Antioxidant","level":2,"score":0.2724646329879761},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.26999425888061523},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.23040583729743958},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.20089688897132874},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.1625017523765564},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.10546305775642395},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000964","descriptor_name":"Antimetabolites, Antineoplastic","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000975","descriptor_name":"Antioxidants","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D002470","descriptor_name":"Cell Survival","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003131","descriptor_name":"Combined Modality Therapy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004050","descriptor_name":"Ditiocarb","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D004050","descriptor_name":"Ditiocarb","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006979","descriptor_name":"Hyperthermia, Induced","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009336","descriptor_name":"Necrosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D011471","descriptor_name":"Prostatic Neoplasms","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D014407","descriptor_name":"Tumor Cells, Cultured","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016923","descriptor_name":"Cell Death","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D016923","descriptor_name":"Cell Death","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D017209","descriptor_name":"Apoptosis","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D017382","descriptor_name":"Reactive Oxygen Species","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D018840","descriptor_name":"HSP70 Heat-Shock Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1046/j.1464-410x.2002.02810.x","doi":"https://doi.org/10.1046/j.1464-410x.2002.02810.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.1464-410x.2002.02810.x","pdf_url":null,"source":{"id":"https://openalex.org/S191188855","display_name":"British Journal of Urology","issn_l":"1464-4096","issn":["1464-4096","1464-410X"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BJU International","raw_type":"journal-article"},{"id":"pmid:12133072","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12133072","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BJU international","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9763000011444092}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":32,"referenced_works":["https://openalex.org/W105638494","https://openalex.org/W149974636","https://openalex.org/W1480914201","https://openalex.org/W1589415602","https://openalex.org/W1934775191","https://openalex.org/W1965784202","https://openalex.org/W1969502142","https://openalex.org/W1977004881","https://openalex.org/W1979632245","https://openalex.org/W1982768676","https://openalex.org/W2001858086","https://openalex.org/W2025652267","https://openalex.org/W2043402257","https://openalex.org/W2051180448","https://openalex.org/W2052707749","https://openalex.org/W2055681319","https://openalex.org/W2056168344","https://openalex.org/W2058579380","https://openalex.org/W2074132377","https://openalex.org/W2084765853","https://openalex.org/W2085306532","https://openalex.org/W2100837269","https://openalex.org/W2114918609","https://openalex.org/W2128729627","https://openalex.org/W2169295801","https://openalex.org/W2202347873","https://openalex.org/W2316022525","https://openalex.org/W2410819654","https://openalex.org/W2467122296","https://openalex.org/W3142105803","https://openalex.org/W4299835378","https://openalex.org/W4302600621"],"related_works":["https://openalex.org/W1984562362","https://openalex.org/W2025652267","https://openalex.org/W2320970371","https://openalex.org/W1568432920","https://openalex.org/W2033620285","https://openalex.org/W2044045413","https://openalex.org/W1965004529","https://openalex.org/W1970142260","https://openalex.org/W2002764921","https://openalex.org/W4214640017"],"abstract_inverted_index":{"OBJECTIVE:":[0],"To":[1],"examine":[2],"the":[3,6,24,43,53,190,231,275,287,404,422,441,467],"relationships":[4],"between":[5,274,286],"form":[7,423],"of":[8,26,35,46,136,192,233,277,395,406,424,430,445,453,455,469],"cell":[9,407,425],"death":[10,426],"(apoptosis":[11],"or":[12,70,78,147,215],"necrosis),":[13],"reactive":[14],"oxygen":[15],"species":[16],"(ROS)":[17],"generation,":[18,84],"superoxide":[19],"dismutase":[20],"(SOD)":[21],"activity":[22,86,293,323,412],"and":[23,52,87,100,107,113,123,143,170,173,194,235,256,260,280,290,312,336,360,364,371,375,390,397,403,409,443,458],"level":[25,91,276,289,350],"heat-shock":[27],"protein":[28],"70":[29,90,349,379],"(hsp":[30],"70)":[31],"expression":[32],"after":[33,133,160,198,223,238,297,341,382],"thermotherapy":[34,66,144,429,448],"PC-3":[36,61,137,431,456],"prostate":[37,470],"cancer":[38],"cells;":[39],"also":[40,131],"assessed":[41],"were":[42,63,92,116,130,245,344],"tumoricidal":[44],"effects":[45],"combined":[47,134],"treatment":[48,135,468],"with":[49,65,120,139,189,229,236,303,339],"both":[50,230],"heat":[51],"antioxidant":[54],"inhibitor":[55],"diethyldithiocarbamate":[56],"(DDC).":[57],"MATERIALS":[58],"AND":[59],"METHODS:":[60],"cells":[62,115,138,162,296,307,327,352,457],"treated":[64],"at":[67,145,163,174,200,213,225,249,261,265,299,318,354,365,384],"42,":[68],"43":[69,146,164,184,216,250,300,355],"44":[71,148,175,201,226,262,319,366,385],"degrees":[72,149,165,176,185,202,217,227,251,263,301,320,356,367,386],"C":[73,150,166,177,186,203,228,252,264,357,368,387],"for":[74,151,167,178,204,253,309,329,358,369,388,466],"30,":[75],"60,":[76,168,254,310],"90":[77,169,255,311,359,389],"120":[79,171,257,313,361,391],"min.":[80,153,206,392],"Cell":[81,155],"proliferation,":[82],"ROS":[83,278,288,401],"SOD":[85,292,322,411],"cellular":[88],"hsp":[89,348],"determined":[93,117],"using":[94],"tetrazolium-based":[95],"cytotoxicity,":[96],"fluorescent":[97],"dichlorofluorescein":[98],"(DCF)":[99],"nitroblue":[101],"tetrazolium":[102],"assays,":[103],"Western":[104],"blot":[105],"analysis":[106],"flow":[108],"cytometry,":[109],"respectively.":[110],"The":[111,393],"apoptotic":[112],"necrotic":[114],"by":[118,211,247,333,428],"staining":[119],"propidium":[121],"iodide":[122],"fluorescein":[124],"isothiocyanate-labelled":[125],"annexin":[126],"V.":[127],"These":[128,415],"variable":[129],"measured":[132],"1":[140],"mmol/L":[141],"DDC":[142,396,459],"60":[152,372],"RESULTS:":[154],"survival":[156],"was":[157,195,208,220,270,324],"significantly":[158,399],"lower":[159],"heating":[161,193,199,212,224,234,248,298,317,383,398],"min":[172,258,314,331,335,362,373],"all":[179,266],"periods":[180],"tested":[181],"(P<0.05).":[182,315,413],"At":[183],"apoptosis":[187,436,454],"increased":[188,210,294,400],"duration":[191,232,444],"similarly":[196],"enhanced":[197,222],"30":[205,330,334,370],"Necrosis":[207],"not":[209],"42":[214],"C,":[218,302,321],"but":[219,283],"markedly":[221],"time":[237,340],"heating.":[239,342,446],"Significant":[240],"increases":[241,346],"in":[242,295,326,347,351,421],"DCF":[243],"production":[244],"induced":[246,427,449],"(P<0.05)":[259,363],"times":[267],"(P<0.010-0.005).":[268],"There":[269,343],"a":[271,418,462],"significant":[272,304,345],"correlation":[273,285],"generation":[279,402],"necrosis":[281,438],"(P<0.001)":[282],"no":[284],"apoptosis.":[291],"differences":[305],"among":[306],"heated":[308,328,353],"After":[316],"maximal":[325],"(P<0.005),":[332],"then":[337],"decreased":[338,381,410],"(P<0.05":[374],"<0.025,":[376],"respectively).":[377],"Hsp":[378],"levels":[380],"combination":[394],"percentage":[405],"death,":[408],"CONCLUSION:":[414],"findings":[416],"show":[417],"qualitative":[419],"change":[420],"cells,":[432],"which":[433],"changed":[434],"from":[435],"to":[437,440],"according":[439],"degree":[442],"Mild":[447],"marginally":[450],"low":[451],"occurrence":[452],"may":[460],"represent":[461],"useful":[463],"future":[464],"strategy":[465],"carcinoma.":[471]},"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":3},{"year":2017,"cited_by_count":2},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":2},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}