{"id":"https://openalex.org/W1493851027","doi":"https://doi.org/10.4049/jimmunol.181.5.3643","title":"Potent Simian Immunodeficiency Virus-Specific Cellular Immune Responses in the Breast Milk of Simian Immunodeficiency Virus-Infected, Lactating Rhesus Monkeys","display_name":"Potent Simian Immunodeficiency Virus-Specific Cellular Immune Responses in the Breast Milk of Simian Immunodeficiency Virus-Infected, Lactating Rhesus Monkeys","publication_year":2008,"publication_date":"2008-09-01","ids":{"openalex":"https://openalex.org/W1493851027","doi":"https://doi.org/10.4049/jimmunol.181.5.3643","mag":"1493851027","pmid":"https://pubmed.ncbi.nlm.nih.gov/18714039","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/2593904"},"language":"en","primary_location":{"id":"doi:10.4049/jimmunol.181.5.3643","doi":"https://doi.org/10.4049/jimmunol.181.5.3643","is_oa":true,"landing_page_url":"https://doi.org/10.4049/jimmunol.181.5.3643","pdf_url":"https://journals.aai.org/jimmunol/article-pdf/181/5/3643/1267065/zim01708003643.pdf","source":{"id":"https://openalex.org/S38008053","display_name":"The Journal of Immunology","issn_l":"0022-1767","issn":["0022-1767","1550-6606"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4320800377","host_organization_name":"American Association of Immunologists","host_organization_lineage":["https://openalex.org/P4320800377"],"host_organization_lineage_names":["American Association of Immunologists"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Immunology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"bronze","oa_url":"https://journals.aai.org/jimmunol/article-pdf/181/5/3643/1267065/zim01708003643.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5056778092","display_name":"Sallie R. Permar","orcid":"https://orcid.org/0000-0003-1438-4554","observed_orcids":["https://orcid.org/0000-0003-1438-4554"]},"institutions":[{"id":"https://openalex.org/I1288882113","display_name":"Boston Children's Hospital","ror":"https://ror.org/00dvg7y05","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1288882113"]},{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sallie R Permar","raw_affiliation_strings":["Division of Infectious Disease, Children\u2019s Hospital Boston, Harvard Medical School , Boston, MA 02115","Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, Harvard Medical School , Boston, MA 02115"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Infectious Disease, Children\u2019s Hospital Boston, Harvard Medical School , Boston, MA 02115","institution_ids":["https://openalex.org/I1288882113","https://openalex.org/I136199984"]},{"raw_affiliation_string":"Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, Harvard Medical School , Boston, MA 02115","institution_ids":["https://openalex.org/I1316535847","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5112188404","display_name":"Helen H. Kang","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Helen H Kang","raw_affiliation_strings":["Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, Harvard Medical School , Boston, MA 02115"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, Harvard Medical School , Boston, MA 02115","institution_ids":["https://openalex.org/I1316535847","https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5036031443","display_name":"Angela Carville","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Angela Carville","raw_affiliation_strings":["New England Regional Primate Research Center, Harvard Medical School , Southboro, MA 01772"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New England Regional Primate Research Center, Harvard Medical School , Southboro, MA 01772","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5013669743","display_name":"Keith G. Mansfield","orcid":"https://orcid.org/0000-0002-5191-270X","observed_orcids":["https://orcid.org/0000-0002-5191-270X"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Keith G Mansfield","raw_affiliation_strings":["New England Regional Primate Research Center, Harvard Medical School , Southboro, MA 01772"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"New England Regional Primate Research Center, Harvard Medical School , Southboro, MA 01772","institution_ids":["https://openalex.org/I136199984"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062329369","display_name":"Rebecca Sue Gelman","orcid":"https://orcid.org/0000-0003-3189-4396","observed_orcids":["https://orcid.org/0000-0003-3189-4396"]},"institutions":[{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]},{"id":"https://openalex.org/I4210117453","display_name":"Dana-Farber Cancer Institute","ror":"https://ror.org/02jzgtq86","country_code":"US","type":"facility","lineage":["https://openalex.org/I4210117453"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Rebecca S Gelman","raw_affiliation_strings":["Dana Farber Cancer Institute, Harvard Medical School , Boston, MA 02115","\u00a7Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Dana Farber Cancer Institute, Harvard Medical School , Boston, MA 02115","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453"]},{"raw_affiliation_string":"\u00a7Dana Farber Cancer Institute, Harvard Medical School, Boston, MA 02115; and","institution_ids":["https://openalex.org/I136199984","https://openalex.org/I4210117453"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5113458828","display_name":"Srinivas S. Rao","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1299303238","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1299303238"]},{"id":"https://openalex.org/I4405268911","display_name":"Vaccine Research Center","ror":"https://ror.org/02fve6a73","country_code":"US","type":"facility","lineage":["https://openalex.org/I4405268911"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Srinivas S Rao","raw_affiliation_strings":["\u00b6Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u00b6Vaccine Research Center, National Institutes of Health, Bethesda, MD 20892","institution_ids":["https://openalex.org/I1299303238","https://openalex.org/I4405268911"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012672197","display_name":"James B. Whitney","orcid":"https://orcid.org/0000-0003-3674-0193","observed_orcids":["https://orcid.org/0000-0003-3674-0193"]},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"James B Whitney","raw_affiliation_strings":["Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, Harvard Medical School , Boston, MA 02115"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, Harvard Medical School , Boston, MA 02115","institution_ids":["https://openalex.org/I1316535847","https://openalex.org/I136199984"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108363333","display_name":"Norman L. Letvin","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1316535847","display_name":"Beth Israel Deaconess Medical Center","ror":"https://ror.org/04drvxt59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1316535847"]},{"id":"https://openalex.org/I136199984","display_name":"Harvard University","ror":"https://ror.org/03vek6s52","country_code":"US","type":"education","lineage":["https://openalex.org/I136199984"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Norman L Letvin","raw_affiliation_strings":["Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, Harvard Medical School , Boston, MA 02115"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Viral Pathogenesis, Beth Israel Deaconess Medical Center, Harvard Medical School , Boston, MA 02115","institution_ids":["https://openalex.org/I1316535847","https://openalex.org/I136199984"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":6,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":null,"fwci":0.8971,"has_fulltext":true,"cited_by_count":24,"citation_normalized_percentile":{"value":0.70138889,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":98},"biblio":{"volume":"181","issue":"5","first_page":"3643","last_page":"3650"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10112","display_name":"HIV Research and Treatment","score":0.9970999956130981,"subfield":{"id":"https://openalex.org/subfields/2406","display_name":"Virology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10082","display_name":"HIV/AIDS Research and Interventions","score":0.001500000013038516,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/simian-immunodeficiency-virus","display_name":"simian immunodeficiency virus","score":0.9620000123977661},{"id":"https://openalex.org/keywords/breast-milk","display_name":"breast milk","score":0.8989999890327454},{"id":"https://openalex.org/keywords/hiv-transmission","display_name":"HIV transmission","score":0.5180000066757202},{"id":"https://openalex.org/keywords/breastfeeding","display_name":"breastfeeding","score":0.49300000071525574},{"id":"https://openalex.org/keywords/cd8-t-cells","display_name":"CD8+ T cells","score":0.7979999780654907},{"id":"https://openalex.org/keywords/viral-load","display_name":"viral load","score":0.5009999871253967},{"id":"https://openalex.org/keywords/lactation","display_name":"lactation","score":0.609000027179718},{"id":"https://openalex.org/keywords/rhesus-macaques","display_name":"rhesus monkeys","score":0.7319999933242798},{"id":"https://openalex.org/keywords/mamu-a-01","display_name":"Mamu-A*01","score":0.8659999966621399},{"id":"https://openalex.org/keywords/viral-set-point","display_name":"viral set point","score":0.5799999833106995}],"concepts":[{"id":"https://openalex.org/C2777995582","wikidata":"https://www.wikidata.org/wiki/Q1890246","display_name":"Simian immunodeficiency virus","level":3,"score":0.9114251136779785},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.7786540985107422},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.6526354551315308},{"id":"https://openalex.org/C2776488936","wikidata":"https://www.wikidata.org/wiki/Q5452918","display_name":"Simian","level":3,"score":0.6400924921035767},{"id":"https://openalex.org/C2775871700","wikidata":"https://www.wikidata.org/wiki/Q22728","display_name":"Breast milk","level":2,"score":0.6177374124526978},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.5937128067016602},{"id":"https://openalex.org/C2777607303","wikidata":"https://www.wikidata.org/wiki/Q641307","display_name":"Immunodeficiency","level":3,"score":0.5827419757843018},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.5449735522270203},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.48635727167129517},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.43741652369499207},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000956","descriptor_name":"Antigens, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007111","descriptor_name":"Immunity, Cellular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007774","descriptor_name":"Lactation","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D008253","descriptor_name":"Macaca mulatta","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008892","descriptor_name":"Milk","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D015302","descriptor_name":"Simian Immunodeficiency Virus","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D016056","descriptor_name":"Immunodominant Epitopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D016097","descriptor_name":"Simian Acquired Immunodeficiency Syndrome","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D016131","descriptor_name":"Lymphocyte Subsets","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018414","descriptor_name":"CD8-Positive T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D019562","descriptor_name":"Viral Load","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.4049/jimmunol.181.5.3643","doi":"https://doi.org/10.4049/jimmunol.181.5.3643","is_oa":true,"landing_page_url":"https://doi.org/10.4049/jimmunol.181.5.3643","pdf_url":"https://journals.aai.org/jimmunol/article-pdf/181/5/3643/1267065/zim01708003643.pdf","source":{"id":"https://openalex.org/S38008053","display_name":"The Journal of Immunology","issn_l":"0022-1767","issn":["0022-1767","1550-6606"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4320800377","host_organization_name":"American Association of Immunologists","host_organization_lineage":["https://openalex.org/P4320800377"],"host_organization_lineage_names":["American Association of Immunologists"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Immunology","raw_type":"journal-article"},{"id":"pmid:18714039","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/18714039","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of immunology (Baltimore, Md. : 1950)","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:1501914","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2593904","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:2593904","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/2593904","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"J Immunol","raw_type":"Text"}],"best_oa_location":{"id":"doi:10.4049/jimmunol.181.5.3643","doi":"https://doi.org/10.4049/jimmunol.181.5.3643","is_oa":true,"landing_page_url":"https://doi.org/10.4049/jimmunol.181.5.3643","pdf_url":"https://journals.aai.org/jimmunol/article-pdf/181/5/3643/1267065/zim01708003643.pdf","source":{"id":"https://openalex.org/S38008053","display_name":"The Journal of Immunology","issn_l":"0022-1767","issn":["0022-1767","1550-6606"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4320800377","host_organization_name":"American Association of Immunologists","host_organization_lineage":["https://openalex.org/P4320800377"],"host_organization_lineage_names":["American Association of Immunologists"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Immunology","raw_type":"journal-article"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9940000176429749,"id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"display_name":"Good health and well-being","score":0.8500000238418579,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2668117508","display_name":"SIV-specific Immunity in breast milk during infection and after vaccination","funder_award_id":"K08AI087992","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G3775530793","display_name":null,"funder_award_id":"L40 AI066264","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G7631011224","display_name":"(CHAVI) Center for HIV/AIDS Vaccine Immunology","funder_award_id":"U01AI067854","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G7726996618","display_name":null,"funder_award_id":"R01AI067854","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G9000904381","display_name":"Harvard University Center for AIDS Research","funder_award_id":"P30AI060354","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320332582","display_name":"Center for AIDS Research, University of Washington","ror":"https://ror.org/00cvxb145"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":true,"grobid_xml":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1493851027.pdf","grobid_xml":"https://content.openalex.org/works/W1493851027.grobid-xml"},"referenced_works_count":62,"referenced_works":["https://openalex.org/W67535539","https://openalex.org/W95554365","https://openalex.org/W128586213","https://openalex.org/W1487648921","https://openalex.org/W1559538353","https://openalex.org/W1571842523","https://openalex.org/W1617110473","https://openalex.org/W1963559981","https://openalex.org/W1965131021","https://openalex.org/W1968947724","https://openalex.org/W1973376781","https://openalex.org/W1993196674","https://openalex.org/W2005930237","https://openalex.org/W2009082030","https://openalex.org/W2010011171","https://openalex.org/W2010444031","https://openalex.org/W2010551795","https://openalex.org/W2031491768","https://openalex.org/W2038675754","https://openalex.org/W2049785056","https://openalex.org/W2051544192","https://openalex.org/W2056253110","https://openalex.org/W2059181398","https://openalex.org/W2062394657","https://openalex.org/W2065616105","https://openalex.org/W2068780088","https://openalex.org/W2069370553","https://openalex.org/W2070310463","https://openalex.org/W2072749590","https://openalex.org/W2073370230","https://openalex.org/W2077710632","https://openalex.org/W2093209837","https://openalex.org/W2095331952","https://openalex.org/W2100258665","https://openalex.org/W2100387196","https://openalex.org/W2102674010","https://openalex.org/W2106750237","https://openalex.org/W2110782358","https://openalex.org/W2113509739","https://openalex.org/W2116476092","https://openalex.org/W2124039449","https://openalex.org/W2130635171","https://openalex.org/W2130675572","https://openalex.org/W2136777660","https://openalex.org/W2138692807","https://openalex.org/W2144882745","https://openalex.org/W2148638005","https://openalex.org/W2152091763","https://openalex.org/W2153560557","https://openalex.org/W2154664295","https://openalex.org/W2155225197","https://openalex.org/W2166583938","https://openalex.org/W2169795300","https://openalex.org/W2170134220","https://openalex.org/W2317460462","https://openalex.org/W2394712212","https://openalex.org/W2396460710","https://openalex.org/W2984129124","https://openalex.org/W4256312031","https://openalex.org/W4285719527","https://openalex.org/W4301859017","https://openalex.org/W4313311519"],"related_works":["https://openalex.org/W7097188261","https://openalex.org/W2109726743","https://openalex.org/W2164717858","https://openalex.org/W1963840088","https://openalex.org/W2095882617","https://openalex.org/W2132803922","https://openalex.org/W2168892888","https://openalex.org/W2043718145","https://openalex.org/W2084660949","https://openalex.org/W2095331952"],"abstract_inverted_index":{"Breast":[0],"milk":[1,32,43,77,124,130,159,177,204,212,237,244],"transmission":[2],"of":[3,9,21,70,146,152,162,168,195,242],"HIV":[4,29],"is":[5],"a":[6,18,208],"leading":[7],"cause":[8],"infant":[10],"HIV/AIDS":[11],"in":[12,40,56,63,73,85,119,157,175,189,202,210,222,235],"the":[13,35,41,47,150,153,163,165,169,185,190,193,196,223],"developing":[14],"world.":[15],"Remarkably,":[16],"only":[17],"small":[19],"minority":[20],"breastfeeding":[22],"infants":[23,48],"born":[24],"to":[25,46,80,83,240],"HIV-infected":[26],"mothers":[27],"contract":[28],"via":[30],"breast":[31,42,57,76,88,123,129,158,176,203,211,236,243],"exposure,":[33],"raising":[34],"possibility":[36],"that":[37,84,161,221],"immune":[38,187,233],"factors":[39],"confer":[44],"protection":[45],"who":[49],"remain":[50],"uninfected.":[51],"To":[52],"model":[53],"HIV-specific":[54],"immunity":[55,156],"milk,":[58],"lactation":[59,75,87],"was":[60,78,133,178,205],"pharmacologically":[61],"induced":[62],"Mamu-A*01(+)":[64],"female":[65],"rhesus":[66],"monkeys.":[67],"The":[68,128],"composition":[69],"lymphocyte":[71,173,200],"subsets":[72],"hormone-induced":[74],"found":[79],"be":[81],"similar":[82],"natural":[86],"milk.":[89],"Hormone-induced":[90],"lactating":[91],"monkeys":[92],"were":[93,117],"inoculated":[94],"i.v.":[95],"with":[96,207],"SIVmac251":[97],"and":[98,110,113,122,143,215],"CD8(+)":[99,171,198],"T":[100,172,199],"lymphocytes":[101],"specific":[102],"for":[103],"two":[104],"immunodominant":[105],"SIV":[106,114],"epitopes,":[107],"Gag":[108],"p11C":[109],"Tat":[111],"TL8,":[112],"viral":[115,131,139,213,226],"load":[116,132,140],"monitored":[118],"peripheral":[120],"blood":[121,224],"during":[125],"acute":[126],"infection.":[127],"1-2":[134],"logs":[135],"lower":[136],"than":[137,180,220],"plasma":[138],"through":[141],"peak":[142,166],"set":[144,227],"point":[145],"viremia.":[147],"Surprisingly,":[148],"whereas":[149],"kinetics":[151],"SIV-specific":[154,170,197],"cellular":[155,186,232],"mirrored":[160],"blood,":[164],"magnitude":[167],"response":[174,188,201,217,234],"more":[179],"twice":[181],"as":[182,184],"high":[183],"blood.":[191],"Furthermore,":[192],"appearance":[194],"associated":[206],"reduction":[209],"load,":[214],"this":[216],"remained":[218],"higher":[219],"after":[225],"point.":[228],"This":[229],"robust":[230],"viral-specific":[231],"may":[238],"contribute":[239],"control":[241],"virus":[245],"replication.":[246]},"counts_by_year":[{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":3},{"year":2012,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}