{"id":"https://openalex.org/W1492485280","doi":"https://doi.org/10.1016/0002-9343(77)90846-4","title":"von Willebrand's disease and hemorrhagic telangiectasia","display_name":"von Willebrand's disease and hemorrhagic telangiectasia","publication_year":1977,"publication_date":"1977-03-01","ids":{"openalex":"https://openalex.org/W1492485280","doi":"https://doi.org/10.1016/0002-9343(77)90846-4","mag":"1492485280","pmid":"https://pubmed.ncbi.nlm.nih.gov/300225"},"language":"en","primary_location":{"id":"doi:10.1016/0002-9343(77)90846-4","doi":"https://doi.org/10.1016/0002-9343(77)90846-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0002-9343(77)90846-4","pdf_url":null,"source":{"id":"https://openalex.org/S186920367","display_name":"The American Journal of Medicine","issn_l":"0002-9343","issn":["0002-9343","1555-7162"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Medicine","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5016103861","display_name":"David J. Ahr","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David J. Ahr","raw_affiliation_strings":["Washington, D.C., USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Washington, D.C., USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027502498","display_name":"Frederick R. Rickles","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Frederick R. Rickles","raw_affiliation_strings":["Washington, D.C., USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Washington, D.C., USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109204885","display_name":"Leon W. Hoyer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Leon W. Hoyer","raw_affiliation_strings":["Farmington, Connecticut, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Farmington, Connecticut, USA","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110721420","display_name":"Dennis S. O\u2019Leary","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Dennis S. O'Leary","raw_affiliation_strings":["Washington, D.C., USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Washington, D.C., USA","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108800678","display_name":"Marcel E. Conrad","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Marcel E. Conrad","raw_affiliation_strings":["Washington, D.C., USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Washington, D.C., USA","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3770,"currency":"USD","value_usd":3770},"apc_paid":null,"fwci":2.4606,"has_fulltext":false,"cited_by_count":58,"citation_normalized_percentile":{"value":0.87722132,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"62","issue":"3","first_page":"452","last_page":"458"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.6801999807357788,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10746","display_name":"Platelet Disorders and Treatments","score":0.6801999807357788,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12199","display_name":"Vascular Anomalies and Treatments","score":0.2847000062465668,"subfield":{"id":"https://openalex.org/subfields/2716","display_name":"Genetics (clinical)"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11280","display_name":"Hemophilia Treatment and Research","score":0.016599999740719795,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/von-willebrand-disease","display_name":"von Willebrand disease","score":0.9860000014305115},{"id":"https://openalex.org/keywords/hereditary-hemorrhagic-telangiectasia","display_name":"hereditary hemorrhagic telangiectasia","score":0.9909999966621399},{"id":"https://openalex.org/keywords/gastrointestinal-bleeding","display_name":"gastrointestinal bleeding","score":0.8529999852180481},{"id":"https://openalex.org/keywords/von-willebrand-factor","display_name":"von Willebrand factor","score":0.8519999980926514},{"id":"https://openalex.org/keywords/factor-viii","display_name":"factor VIII","score":0.8140000104904175},{"id":"https://openalex.org/keywords/mucocutaneous-bleeding","display_name":"mucocutaneous bleeding","score":0.7440000176429749},{"id":"https://openalex.org/keywords/family-screening","display_name":"family screening","score":0.6340000033378601},{"id":"https://openalex.org/keywords/transfusion-response","display_name":"transfusion response","score":0.8169999718666077}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9502408504486084},{"id":"https://openalex.org/C2776330896","wikidata":"https://www.wikidata.org/wiki/Q1634800","display_name":"Telangiectasia","level":2,"score":0.9402148723602295},{"id":"https://openalex.org/C156662089","wikidata":"https://www.wikidata.org/wiki/Q6931223","display_name":"Mucocutaneous zone","level":3,"score":0.7069082260131836},{"id":"https://openalex.org/C2778780528","wikidata":"https://www.wikidata.org/wiki/Q709360","display_name":"Von Willebrand disease","level":4,"score":0.6826891899108887},{"id":"https://openalex.org/C2779394231","wikidata":"https://www.wikidata.org/wiki/Q412310","display_name":"Von Willebrand factor","level":3,"score":0.6324462294578552},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.489241361618042},{"id":"https://openalex.org/C2778080469","wikidata":"https://www.wikidata.org/wiki/Q1495657","display_name":"Gastrointestinal bleeding","level":2,"score":0.42243391275405884},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.3194769024848938},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.3180781602859497},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.28715604543685913},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.2712647318840027},{"id":"https://openalex.org/C89560881","wikidata":"https://www.wikidata.org/wiki/Q101026","display_name":"Platelet","level":2,"score":0.22443273663520813}],"mesh":[{"descriptor_ui":"D001780","descriptor_name":"Blood Coagulation Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005169","descriptor_name":"Factor VIII","qualifier_ui":"Q000032","qualifier_name":"analysis","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006471","descriptor_name":"Gastrointestinal Hemorrhage","qualifier_ui":"Q000097","qualifier_name":"blood","is_major_topic":false},{"descriptor_ui":"D006471","descriptor_name":"Gastrointestinal Hemorrhage","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010375","descriptor_name":"Pedigree","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012008","descriptor_name":"Recurrence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013683","descriptor_name":"Telangiectasia, Hereditary Hemorrhagic","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D013683","descriptor_name":"Telangiectasia, Hereditary Hemorrhagic","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D014842","descriptor_name":"von Willebrand Diseases","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D014842","descriptor_name":"von Willebrand Diseases","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1016/0002-9343(77)90846-4","doi":"https://doi.org/10.1016/0002-9343(77)90846-4","is_oa":false,"landing_page_url":"https://doi.org/10.1016/0002-9343(77)90846-4","pdf_url":null,"source":{"id":"https://openalex.org/S186920367","display_name":"The American Journal of Medicine","issn_l":"0002-9343","issn":["0002-9343","1555-7162"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American Journal of Medicine","raw_type":"journal-article"},{"id":"pmid:300225","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/300225","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The American journal of medicine","raw_type":"Case Reports"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.9940000176429749}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":74,"referenced_works":["https://openalex.org/W20299691","https://openalex.org/W86417293","https://openalex.org/W110617401","https://openalex.org/W140535456","https://openalex.org/W160258599","https://openalex.org/W161461363","https://openalex.org/W170513206","https://openalex.org/W267077592","https://openalex.org/W1507763922","https://openalex.org/W1928912859","https://openalex.org/W1965850649","https://openalex.org/W1965975940","https://openalex.org/W1966694050","https://openalex.org/W1970241558","https://openalex.org/W1972165192","https://openalex.org/W1973306868","https://openalex.org/W1980804111","https://openalex.org/W1992650719","https://openalex.org/W1993576058","https://openalex.org/W1994085192","https://openalex.org/W1994868311","https://openalex.org/W2001201546","https://openalex.org/W2007499970","https://openalex.org/W2008193699","https://openalex.org/W2011317460","https://openalex.org/W2012214760","https://openalex.org/W2014166250","https://openalex.org/W2016103647","https://openalex.org/W2019570259","https://openalex.org/W2029314356","https://openalex.org/W2036129290","https://openalex.org/W2039069250","https://openalex.org/W2042628078","https://openalex.org/W2044054873","https://openalex.org/W2050923504","https://openalex.org/W2052879843","https://openalex.org/W2055431447","https://openalex.org/W2058530852","https://openalex.org/W2059197944","https://openalex.org/W2060580925","https://openalex.org/W2063536625","https://openalex.org/W2073941685","https://openalex.org/W2077603362","https://openalex.org/W2089401176","https://openalex.org/W2092745603","https://openalex.org/W2129417376","https://openalex.org/W2136994514","https://openalex.org/W2158841112","https://openalex.org/W2164511280","https://openalex.org/W2177941176","https://openalex.org/W2225112376","https://openalex.org/W2257693468","https://openalex.org/W2294264511","https://openalex.org/W2314189699","https://openalex.org/W2316509568","https://openalex.org/W2322148932","https://openalex.org/W2333149001","https://openalex.org/W2333867246","https://openalex.org/W2335302072","https://openalex.org/W2396883455","https://openalex.org/W2403228077","https://openalex.org/W2408988764","https://openalex.org/W2410580551","https://openalex.org/W2413008145","https://openalex.org/W2414389162","https://openalex.org/W2415116911","https://openalex.org/W2415798638","https://openalex.org/W2416853421","https://openalex.org/W2555352600","https://openalex.org/W2980015831","https://openalex.org/W3150128776","https://openalex.org/W4214901863","https://openalex.org/W4252606864","https://openalex.org/W4299822935"],"related_works":["https://openalex.org/W2066275100","https://openalex.org/W4244228767","https://openalex.org/W2408821689","https://openalex.org/W2406039527","https://openalex.org/W2185152077","https://openalex.org/W2001201546","https://openalex.org/W2063536625","https://openalex.org/W4391817572","https://openalex.org/W2266677345","https://openalex.org/W4412642709"],"abstract_inverted_index":null,"counts_by_year":[{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2018,"cited_by_count":4},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}