{"id":"https://openalex.org/W1490835233","doi":"https://doi.org/10.4049/jimmunol.176.1.291","title":"Ly9 (CD229)-Deficient Mice Exhibit T Cell Defects yet Do Not Share Several Phenotypic Characteristics Associated with SLAM- and SAP-Deficient Mice","display_name":"Ly9 (CD229)-Deficient Mice Exhibit T Cell Defects yet Do Not Share Several Phenotypic Characteristics Associated with SLAM- and SAP-Deficient Mice","publication_year":2006,"publication_date":"2006-01-01","ids":{"openalex":"https://openalex.org/W1490835233","doi":"https://doi.org/10.4049/jimmunol.176.1.291","mag":"1490835233","pmid":"https://pubmed.ncbi.nlm.nih.gov/16365421"},"language":"en","primary_location":{"id":"doi:10.4049/jimmunol.176.1.291","doi":"https://doi.org/10.4049/jimmunol.176.1.291","is_oa":false,"landing_page_url":"https://doi.org/10.4049/jimmunol.176.1.291","pdf_url":null,"source":{"id":"https://openalex.org/S38008053","display_name":"The Journal of Immunology","issn_l":"0022-1767","issn":["0022-1767","1550-6606"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4320800377","host_organization_name":"American Association of Immunologists","host_organization_lineage":["https://openalex.org/P4320800377"],"host_organization_lineage_names":["American Association of Immunologists"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Immunology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026016872","display_name":"Daniel B. Graham","orcid":"https://orcid.org/0000-0002-8403-8115","observed_orcids":["https://orcid.org/0000-0002-8403-8115"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Daniel B Graham","raw_affiliation_strings":["Department of Immunology , Rochester, MN 55905","*Department of Immunology,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology , Rochester, MN 55905","institution_ids":[]},{"raw_affiliation_string":"*Department of Immunology,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110223302","display_name":"Michael P. Bell","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michael P Bell","raw_affiliation_strings":["Department of Immunology , Rochester, MN 55905","*Department of Immunology,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology , Rochester, MN 55905","institution_ids":[]},{"raw_affiliation_string":"*Department of Immunology,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5079535759","display_name":"Megan M. McCausland","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1311191458","display_name":"La Jolla Institute for Immunology","ror":"https://ror.org/05vkpd318","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1311191458"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Megan M McCausland","raw_affiliation_strings":["\u00a7Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, San Diego, CA 92121"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u00a7Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, San Diego, CA 92121","institution_ids":["https://openalex.org/I1311191458"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110058830","display_name":"Catherine J. Huntoon","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Catherine J Huntoon","raw_affiliation_strings":["Department of Immunology , Rochester, MN 55905","*Department of Immunology,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology , Rochester, MN 55905","institution_ids":[]},{"raw_affiliation_string":"*Department of Immunology,","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5072542382","display_name":"Jan van Deursen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jan van Deursen","raw_affiliation_strings":["Department of Pediatric and Adolescent Medicine , Rochester, MN 55905","\u2020Department of Pediatric and Adolescent Medicine, and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatric and Adolescent Medicine , Rochester, MN 55905","institution_ids":[]},{"raw_affiliation_string":"\u2020Department of Pediatric and Adolescent Medicine, and","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5018558381","display_name":"William A. Faubion","orcid":"https://orcid.org/0000-0003-1291-5745","observed_orcids":["https://orcid.org/0000-0003-1291-5745"]},"institutions":[{"id":"https://openalex.org/I1330342723","display_name":"Mayo Clinic","ror":"https://ror.org/02qp3tb03","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1330342723"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"William A Faubion","raw_affiliation_strings":["Department of Gastroenterology, Mayo Clinic College of Medicine , Rochester, MN 55905","\u2021Department of Gastroenterology, Mayo Clinic College of Medicine, Rochester, MN 55905; and"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Gastroenterology, Mayo Clinic College of Medicine , Rochester, MN 55905","institution_ids":["https://openalex.org/I1330342723"]},{"raw_affiliation_string":"\u2021Department of Gastroenterology, Mayo Clinic College of Medicine, Rochester, MN 55905; and","institution_ids":["https://openalex.org/I1330342723"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5030160770","display_name":"Shane Crotty","orcid":"https://orcid.org/0000-0002-6484-6262","observed_orcids":["https://orcid.org/0000-0002-6484-6262"]},"institutions":[{"id":"https://openalex.org/I1311191458","display_name":"La Jolla Institute for Immunology","ror":"https://ror.org/05vkpd318","country_code":"US","type":"nonprofit","lineage":["https://openalex.org/I1311191458"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Shane Crotty","raw_affiliation_strings":["\u00a7Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, San Diego, CA 92121"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"\u00a7Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, San Diego, CA 92121","institution_ids":["https://openalex.org/I1311191458"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5108805419","display_name":"DAVID J. McKEAN","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"David J McKean","raw_affiliation_strings":["Department of Immunology , Rochester, MN 55905","*Department of Immunology,"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Immunology , Rochester, MN 55905","institution_ids":[]},{"raw_affiliation_string":"*Department of Immunology,","institution_ids":[]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3500,"currency":"USD","value_usd":3500},"apc_paid":null,"fwci":3.242,"has_fulltext":false,"cited_by_count":87,"citation_normalized_percentile":{"value":0.92375449,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"176","issue":"1","first_page":"291","last_page":"300"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.8115000128746033,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10031","display_name":"T-cell and B-cell Immunology","score":0.8115000128746033,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11725","display_name":"Immunodeficiency and Autoimmune Disorders","score":0.17219999432563782,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10371","display_name":"Immune Response and Inflammation","score":0.004000000189989805,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/ly9","display_name":"LY9","score":0.8209999799728394},{"id":"https://openalex.org/keywords/cd229","display_name":"CD229","score":0.9950000047683716},{"id":"https://openalex.org/keywords/slam-family-receptors","display_name":"SLAM family receptors","score":0.9390000104904175},{"id":"https://openalex.org/keywords/simultaneous-localization-and-mapping","display_name":"SLAM","score":0.6790000200271606},{"id":"https://openalex.org/keywords/slam-associated-protein","display_name":"SLAM-associated protein","score":0.8029999732971191},{"id":"https://openalex.org/keywords/x-linked-lymphoproliferative-disease","display_name":"X-linked lymphoproliferative disease","score":0.9200000166893005},{"id":"https://openalex.org/keywords/t-cell-activation","display_name":"T cell activation","score":0.9079999923706055},{"id":"https://openalex.org/keywords/th2-polarization","display_name":"Th2 polarization","score":0.7850000262260437},{"id":"https://openalex.org/keywords/il-4","display_name":"IL-4","score":0.8880000114440918},{"id":"https://openalex.org/keywords/interleukin-2","display_name":"interleukin-2","score":0.949999988079071},{"id":"https://openalex.org/keywords/macrophage-function","display_name":"macrophage function","score":0.8159999847412109},{"id":"https://openalex.org/keywords/nkt-cell-development","display_name":"NKT cell development","score":0.8790000081062317},{"id":"https://openalex.org/keywords/lymphocytic-choriomeningitis-virus","display_name":"lymphocytic choriomeningitis virus","score":0.9440000057220459},{"id":"https://openalex.org/keywords/t-cell-proliferation","display_name":"T cell proliferation","score":0.5}],"concepts":[{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6736559867858887},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.587422251701355},{"id":"https://openalex.org/C19317047","wikidata":"https://www.wikidata.org/wiki/Q412037","display_name":"T-cell receptor","level":4,"score":0.5724323987960815},{"id":"https://openalex.org/C127716648","wikidata":"https://www.wikidata.org/wiki/Q104053","display_name":"Phenotype","level":3,"score":0.5419898629188538},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.5069366097450256},{"id":"https://openalex.org/C148125776","wikidata":"https://www.wikidata.org/wiki/Q1622348","display_name":"CD28","level":4,"score":0.48319900035858154},{"id":"https://openalex.org/C24998067","wikidata":"https://www.wikidata.org/wiki/Q4114622","display_name":"Stimulation","level":2,"score":0.4650237560272217},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.4596303403377533},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.4593278765678406},{"id":"https://openalex.org/C2776090121","wikidata":"https://www.wikidata.org/wiki/Q193529","display_name":"T cell","level":3,"score":0.325700044631958},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.20286065340042114},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.1807289719581604},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.1403055489063263}],"mesh":[{"descriptor_ui":"D000071176","descriptor_name":"Signaling Lymphocytic Activation Molecule Family","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000071177","descriptor_name":"Signaling Lymphocytic Activation Molecule Family Member 1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005434","descriptor_name":"Flow Cytometry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006023","descriptor_name":"Glycoproteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D006023","descriptor_name":"Glycoproteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007136","descriptor_name":"Immunoglobulins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D007136","descriptor_name":"Immunoglobulins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007694","descriptor_name":"Killer Cells, Natural","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008213","descriptor_name":"Lymphocyte Activation","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008216","descriptor_name":"Lymphocytic Choriomeningitis","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008217","descriptor_name":"Lymphocytic choriomeningitis virus","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D008264","descriptor_name":"Macrophages","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D011956","descriptor_name":"Receptors, Cell Surface","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013601","descriptor_name":"T-Lymphocytes","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D015703","descriptor_name":"Antigens, CD","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D015703","descriptor_name":"Antigens, CD","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D016133","descriptor_name":"Polymerase Chain Reaction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D047908","descriptor_name":"Intracellular Signaling Peptides and Proteins","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":true},{"descriptor_ui":"D047908","descriptor_name":"Intracellular Signaling Peptides and Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.4049/jimmunol.176.1.291","doi":"https://doi.org/10.4049/jimmunol.176.1.291","is_oa":false,"landing_page_url":"https://doi.org/10.4049/jimmunol.176.1.291","pdf_url":null,"source":{"id":"https://openalex.org/S38008053","display_name":"The Journal of Immunology","issn_l":"0022-1767","issn":["0022-1767","1550-6606"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-b","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4320800377","host_organization_name":"American Association of Immunologists","host_organization_lineage":["https://openalex.org/P4320800377"],"host_organization_lineage_names":["American Association of Immunologists"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Journal of Immunology","raw_type":"journal-article"},{"id":"pmid:16365421","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/16365421","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of immunology (Baltimore, Md. : 1950)","raw_type":"Comparative Study"}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being","score":0.8371999859809875}],"study_designs":[],"awards":[{"id":"https://openalex.org/G151254113","display_name":"COACTIVATION SIGNALS REGULATE THYMOCYTE DEVELOPMENT","funder_award_id":"R01AI044959","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"},{"id":"https://openalex.org/G302415004","display_name":"Ph. D. Training Program in Basic Immunology","funder_award_id":"T32AI007425","funder_id":"https://openalex.org/F4320337355","funder_display_name":"National Institute of Allergy and Infectious Diseases"}],"funders":[{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337355","display_name":"National Institute of Allergy and Infectious Diseases","ror":"https://ror.org/043z4tv69"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":27,"referenced_works":["https://openalex.org/W1487843912","https://openalex.org/W1510178802","https://openalex.org/W1520006748","https://openalex.org/W1522096076","https://openalex.org/W1530742573","https://openalex.org/W1567696770","https://openalex.org/W1777336049","https://openalex.org/W1971382394","https://openalex.org/W1988441535","https://openalex.org/W1990755959","https://openalex.org/W2014686737","https://openalex.org/W2031006767","https://openalex.org/W2040678488","https://openalex.org/W2053104039","https://openalex.org/W2076124836","https://openalex.org/W2094555693","https://openalex.org/W2099465341","https://openalex.org/W2110045901","https://openalex.org/W2118362622","https://openalex.org/W2122693469","https://openalex.org/W2131810356","https://openalex.org/W2131925046","https://openalex.org/W2133864160","https://openalex.org/W2136589340","https://openalex.org/W2142746570","https://openalex.org/W2156961356","https://openalex.org/W2168821585"],"related_works":["https://openalex.org/W1966006735","https://openalex.org/W2169317161","https://openalex.org/W1991218269","https://openalex.org/W7098266109","https://openalex.org/W2138576885","https://openalex.org/W2017213329","https://openalex.org/W2055336436","https://openalex.org/W2276150087","https://openalex.org/W1984036332","https://openalex.org/W2020212971"],"abstract_inverted_index":{"Signaling":[0],"lymphocyte":[1],"activation":[2],"molecule":[3,29],"(SLAM)":[4],"family":[5,19,57],"receptors":[6,20],"are":[7],"critically":[8],"involved":[9,249],"in":[10,40,114,120,128,138,164,176,185,195,242,250],"modulating":[11],"innate":[12],"and":[13,81,89,112,145,155,204,208,230,236],"adaptive":[14],"immune":[15],"responses.":[16],"Several":[17],"SLAM":[18,56],"have":[21,72,77,167,217],"been":[22],"shown":[23],"to":[24,45,63,122,143,212],"interact":[25,64],"with":[26,65,85,104,110,162,227],"the":[27,55,67,123],"adaptor":[28],"SAP;":[30],"however,":[31],"subsequent":[32],"intracellular":[33],"signaling":[34],"is":[35,61,118,132,247],"poorly":[36,154],"defined.":[37],"Notably,":[38],"mutations":[39],"SLAM-associated":[41],"protein":[42],"(SAP)":[43],"lead":[44],"X-linked":[46],"lymphoproliferative":[47],"disease,":[48],"a":[49,99,239],"rare":[50],"but":[51,131],"fatal":[52],"immunodeficiency.":[53],"Although":[54,233],"member":[58],"Ly9":[59],"(CD229)":[60],"known":[62],"SAP,":[66],"functions":[68],"of":[69,87,201],"this":[70],"receptor":[71],"remained":[73],"elusive.":[74],"Therefore,":[75],"we":[76],"generated":[78],"Ly9-/-":[79,95,151,171,189],"mice":[80,130,152,190,194,224],"compared":[82,226],"their":[83],"phenotype":[84],"that":[86,94,136,170,196],"SLAM-/-":[88,129,144,186,229],"SAP-/-":[90,139,146,193,231],"mice.":[91,140,232],"We":[92,166,216],"report":[93],"T":[96,148,207,252],"cells":[97,149,203],"exhibit":[98,173],"mild":[100],"Th2":[101,126,244],"defect":[102,117,127],"associated":[103],"reduced":[105],"IL-4":[106],"production":[107,178],"after":[108,159],"stimulation":[109,161],"anti-TCR":[111],"anti-CD28":[113],"vitro.":[115,165],"This":[116],"similar":[119],"magnitude":[121],"previously":[124],"reported":[125],"more":[133],"subtle":[134],"than":[135],"observed":[137,184],"In":[141],"contrast":[142],"mice,":[147],"from":[150,192],"proliferate":[153],"produce":[156],"little":[157],"IL-2":[158],"suboptimal":[160],"anti-CD3":[163],"also":[168],"found":[169],"macrophages":[172],"no":[174],"defects":[175],"cytokine":[177],"or":[179],"bacterial":[180],"killing":[181],"as":[182,225],"was":[183],"macrophages.":[187],"Additionally,":[188],"differ":[191],"they":[197],"foster":[198],"normal":[199],"development":[200],"NKT":[202],"mount":[205],"appropriate":[206],"B":[209],"cell":[210,253],"responses":[211],"lymphocytic":[213],"choriomeningitis":[214],"virus.":[215],"identified":[218],"significant":[219],"phenotypic":[220],"differences":[221],"between":[222],"Ly-9-/-":[223],"both":[228],"Ly9,":[234],"SLAM,":[235],"SAP":[237],"play":[238],"common":[240],"role":[241],"promoting":[243],"polarization,":[245],"Ly-9":[246],"uniquely":[248],"enhancing":[251],"activation.":[254]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":5},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":4},{"year":2015,"cited_by_count":4},{"year":2014,"cited_by_count":1},{"year":2013,"cited_by_count":4},{"year":2012,"cited_by_count":3}],"updated_date":"2026-11-11T12:16:26.678958","created_date":"2016-06-24T00:00:00"}