{"id":"https://openalex.org/W1488028899","doi":null,"title":"Grave's disease - HAART induced immune reconstitution syndrome","display_name":"Grave's disease - HAART induced immune reconstitution syndrome","publication_year":2008,"publication_date":"2008-05-01","ids":{"openalex":"https://openalex.org/W1488028899","mag":"1488028899"},"language":"en","primary_location":{"id":"mag:1488028899","doi":null,"is_oa":true,"landing_page_url":"https://www.thetrp.net/article.asp?issn=0973-0354;year=2008;volume=5;issue=2;spage=48;epage=50;aulast=Jegan;type=0;aid=ThyroidResPract_2008_5_2_48_90583","pdf_url":null,"source":{"id":"https://openalex.org/S2764746808","display_name":"Thyroid Research and Practice","issn_l":"0973-0354","issn":["0973-0354","2250-1452"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Thyroid Research and Practice","raw_type":null},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":true,"oa_status":"diamond","oa_url":"https://www.thetrp.net/article.asp?issn=0973-0354;year=2008;volume=5;issue=2;spage=48;epage=50;aulast=Jegan;type=0;aid=ThyroidResPract_2008_5_2_48_90583","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5080630092","display_name":"P Jegan","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210165321","display_name":"Manipal Hospital","ror":"https://ror.org/05mryn396","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210165321"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"P Jegan","raw_affiliation_strings":["Department of Diabetes & Endocrinology, Manipal Hospital and Department of Chest, Wockhardt Hospital, Bangalore-560017, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diabetes & Endocrinology, Manipal Hospital and Department of Chest, Wockhardt Hospital, Bangalore-560017, India","institution_ids":["https://openalex.org/I4210165321"]}]},{"author_position":"middle","author":{"id":null,"display_name":"R. Menaka","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210165321","display_name":"Manipal Hospital","ror":"https://ror.org/05mryn396","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210165321"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"R. Menaka","raw_affiliation_strings":["Department of Diabetes & Endocrinology, Manipal Hospital and Department of Chest, Wockhardt Hospital, Bangalore-560017, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diabetes & Endocrinology, Manipal Hospital and Department of Chest, Wockhardt Hospital, Bangalore-560017, India","institution_ids":["https://openalex.org/I4210165321"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103505324","display_name":"KS Satish","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210165321","display_name":"Manipal Hospital","ror":"https://ror.org/05mryn396","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210165321"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"KS Satish","raw_affiliation_strings":["Department of Diabetes & Endocrinology, Manipal Hospital and Department of Chest, Wockhardt Hospital, Bangalore-560017, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diabetes & Endocrinology, Manipal Hospital and Department of Chest, Wockhardt Hospital, Bangalore-560017, India","institution_ids":["https://openalex.org/I4210165321"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5017435417","display_name":"Arpita Bhattacharyya","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210165321","display_name":"Manipal Hospital","ror":"https://ror.org/05mryn396","country_code":"IN","type":"healthcare","lineage":["https://openalex.org/I4210165321"]}],"countries":["IN"],"is_corresponding":false,"raw_author_name":"Arpita Bhattacharyya","raw_affiliation_strings":["Department of Diabetes & Endocrinology, Manipal Hospital and Department of Chest, Wockhardt Hospital, Bangalore-560017, India"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Diabetes & Endocrinology, Manipal Hospital and Department of Chest, Wockhardt Hospital, Bangalore-560017, India","institution_ids":["https://openalex.org/I4210165321"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210165321"],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.11253544,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"5","issue":"2","first_page":"48","last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9096999764442444,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10293","display_name":"Thyroid Disorders and Treatments","score":0.9096999764442444,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11655","display_name":"HIV-related health complications and treatments","score":0.014499999582767487,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11538","display_name":"Ophthalmology and Eye Disorders","score":0.009200000204145908,"subfield":{"id":"https://openalex.org/subfields/2731","display_name":"Ophthalmology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/graves-disease","display_name":"Graves' disease","score":0.9710000157356262},{"id":"https://openalex.org/keywords/immune-reconstitution-inflammatory-syndrome","display_name":"immune reconstitution inflammatory syndrome","score":0.9700000286102295},{"id":"https://openalex.org/keywords/hiv-infection","display_name":"HIV infection","score":0.7720000147819519},{"id":"https://openalex.org/keywords/highly-active-antiretroviral-therapy","display_name":"highly active antiretroviral therapy","score":0.9520000219345093},{"id":"https://openalex.org/keywords/thyrotoxicosis","display_name":"thyrotoxicosis","score":0.968999981880188},{"id":"https://openalex.org/keywords/radioiodine-ablation","display_name":"radioiodine ablation","score":0.8149999976158142},{"id":"https://openalex.org/keywords/antithyroid-drugs","display_name":"antithyroid drugs","score":0.7870000004768372},{"id":"https://openalex.org/keywords/hypothyroidism","display_name":"hypothyroidism","score":0.859000027179718},{"id":"https://openalex.org/keywords/beta-blockers","display_name":"beta-blockers","score":0.46799999475479126},{"id":"https://openalex.org/keywords/methimazole","display_name":"methimazole","score":0.6919999718666077}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9252375364303589},{"id":"https://openalex.org/C2993143319","wikidata":"https://www.wikidata.org/wiki/Q583050","display_name":"Antiretroviral therapy","level":4,"score":0.7556777000427246},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5781500339508057},{"id":"https://openalex.org/C8891405","wikidata":"https://www.wikidata.org/wiki/Q1059","display_name":"Immune system","level":2,"score":0.5739225745201111},{"id":"https://openalex.org/C2776652619","wikidata":"https://www.wikidata.org/wiki/Q16483","display_name":"Graves' disease","level":3,"score":0.5282948017120361},{"id":"https://openalex.org/C2779778235","wikidata":"https://www.wikidata.org/wiki/Q539986","display_name":"Immune reconstitution inflammatory syndrome","level":5,"score":0.47815069556236267},{"id":"https://openalex.org/C526584372","wikidata":"https://www.wikidata.org/wiki/Q16399","display_name":"Thyroid","level":2,"score":0.47361040115356445},{"id":"https://openalex.org/C3013748606","wikidata":"https://www.wikidata.org/wiki/Q15787","display_name":"Human immunodeficiency virus (HIV)","level":2,"score":0.4421154260635376},{"id":"https://openalex.org/C2909564963","wikidata":"https://www.wikidata.org/wiki/Q1365501","display_name":"Antithyroid drugs","level":4,"score":0.4251483380794525},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.382470965385437},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.35967928171157837},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.32874661684036255},{"id":"https://openalex.org/C142462285","wikidata":"https://www.wikidata.org/wiki/Q2528140","display_name":"Viral load","level":3,"score":0.1523182988166809}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:1488028899","doi":null,"is_oa":true,"landing_page_url":"https://www.thetrp.net/article.asp?issn=0973-0354;year=2008;volume=5;issue=2;spage=48;epage=50;aulast=Jegan;type=0;aid=ThyroidResPract_2008_5_2_48_90583","pdf_url":null,"source":{"id":"https://openalex.org/S2764746808","display_name":"Thyroid Research and Practice","issn_l":"0973-0354","issn":["0973-0354","2250-1452"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Thyroid Research and Practice","raw_type":null}],"best_oa_location":{"id":"mag:1488028899","doi":null,"is_oa":true,"landing_page_url":"https://www.thetrp.net/article.asp?issn=0973-0354;year=2008;volume=5;issue=2;spage=48;epage=50;aulast=Jegan;type=0;aid=ThyroidResPract_2008_5_2_48_90583","pdf_url":null,"source":{"id":"https://openalex.org/S2764746808","display_name":"Thyroid Research and Practice","issn_l":"0973-0354","issn":["0973-0354","2250-1452"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj"],"host_organization":"https://openalex.org/P4310320448","host_organization_name":"Medknow","host_organization_lineage":["https://openalex.org/P4310320448","https://openalex.org/P4310318547"],"host_organization_lineage_names":["Medknow","Wolters Kluwer"],"type":"journal"},"license":"cc-by-nc-nd","license_id":"https://openalex.org/licenses/cc-by-nc-nd","version":null,"is_accepted":false,"is_published":false,"raw_source_name":"Thyroid Research and Practice","raw_type":null},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/case-report","display_name":"Case Report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W1981812592","https://openalex.org/W2040320862","https://openalex.org/W2131914792","https://openalex.org/W3165996181","https://openalex.org/W2079169004","https://openalex.org/W2027995394","https://openalex.org/W2013296377","https://openalex.org/W275710625","https://openalex.org/W2074046663","https://openalex.org/W3203153192"],"abstract_inverted_index":{"Highly":[0],"Active":[1],"Anti":[2],"Retroviral":[3],"Therapy":[4],"(HAART)":[5],"for":[6],"the":[7,16,24,62,122],"treatment":[8,144],"of":[9,15,26,64,71,124,133,151],"HIV":[10,50],"causes":[11],"a":[12,30,45,94,130],"paradoxical":[13],"deterioration":[14],"clinical":[17,96],"status":[18],"after":[19,61,93,121,148],"it's":[20],"initiation,":[21],"due":[22],"to":[23,29,76],"reactivation":[25],"immune":[27],"response":[28],"latent":[31],"or":[32,118],"sub-clinical":[33],"process.":[34],"This":[35],"phenomenon":[36],"is":[37,129,141],"called":[38],"Immune":[39,110],"Reconstitution":[40],"Syndromes":[41],"(1RS).":[42],"We":[43],"report":[44],"48-year":[46],"old":[47],"man":[48],"with":[49,135,153],"infection":[51],"who":[52],"was":[53,74,82,91],"started":[54,83],"on":[55,84,107],"combination":[56],"antiretroviral":[57,125],"therapy.":[58,109,126],"Three":[59],"years":[60,120],"initiation":[63,123],"therapy,":[65],"he":[66],"developed":[67],"symptoms":[68],"and":[69,81,87,97,103],"signs":[70],"thyrotoxicosis.":[72],"He":[73,100],"diagnosd":[75],"have":[77],"Graves":[78],"'":[79],"disease":[80,114],"beta":[85],"blockers":[86],"Neomercazole.":[88],"Radioactive":[89],"iodine":[90],"given":[92],"good":[95],"biochemical":[98],"improvement.":[99],"became":[101],"hypothyroid":[102],"currently":[104],"doing":[105],"well":[106],"replacement":[108],"reconstitution":[111],"syndrome":[112],"Grave's":[113],"may":[115],"appear":[116],"months":[117],"even":[119],"As":[127],"there":[128],"high":[131],"chance":[132],"relapse":[134],"anti-thyroid":[136,154],"drugs,":[137],"radioiodine":[138],"ablation":[139],"probably":[140],"more":[142],"appropriate":[143],"in":[145],"this":[146],"condition":[147],"initial":[149],"stabilization":[150],"thyrotoxicosis":[152],"drugs":[155]},"counts_by_year":[],"updated_date":"2026-10-28T10:33:24.094632","created_date":"2016-06-24T00:00:00"}