{"id":"https://openalex.org/W1487705489","doi":"https://doi.org/10.1186/1471-230x-4-26","title":"An unusual case of an ulcerative colitis flare resulting in disseminated intravascular coagulopathy and a bladder hematoma: a case report","display_name":"An unusual case of an ulcerative colitis flare resulting in disseminated intravascular coagulopathy and a bladder hematoma: a case report","publication_year":2004,"publication_date":"2004-10-07","ids":{"openalex":"https://openalex.org/W1487705489","doi":"https://doi.org/10.1186/1471-230x-4-26","mag":"1487705489","pmid":"https://pubmed.ncbi.nlm.nih.gov/15471542","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/526371"},"language":"en","primary_location":{"id":"doi:10.1186/1471-230x-4-26","doi":"https://doi.org/10.1186/1471-230x-4-26","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-230x-4-26","pdf_url":"https://link.springer.com/content/pdf/10.1186/1471-230X-4-26.pdf","source":{"id":"https://openalex.org/S180811554","display_name":"BMC Gastroenterology","issn_l":"1471-230X","issn":["1471-230X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Gastroenterology","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"gold","oa_url":"https://link.springer.com/content/pdf/10.1186/1471-230X-4-26.pdf","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5049522610","display_name":"David L. Suskind","orcid":"https://orcid.org/0000-0002-3524-5150","observed_orcids":["https://orcid.org/0000-0002-3524-5150"]},"institutions":[{"id":"https://openalex.org/I1295499534","display_name":"Seattle Children's Hospital","ror":"https://ror.org/01njes783","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295499534"]},{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"David L Suskind","raw_affiliation_strings":["Department of Pediatrics, Seattle Children's Hospital and Regional Medical Center, University of Washington, 4800 Sand Point Way NE, Seattle, Washington, USA. david.suskind@seattlechildrens.org","Department of Pediatrics, Seattle Children's Hospital and Regional Medical Center, University of Washington, Washington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Seattle Children's Hospital and Regional Medical Center, University of Washington, 4800 Sand Point Way NE, Seattle, Washington, USA. david.suskind@seattlechildrens.org","institution_ids":["https://openalex.org/I1295499534","https://openalex.org/I201448701"]},{"raw_affiliation_string":"Department of Pediatrics, Seattle Children's Hospital and Regional Medical Center, University of Washington, Washington, USA","institution_ids":["https://openalex.org/I1295499534","https://openalex.org/I201448701"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103061016","display_name":"Karen F. Murray","orcid":"https://orcid.org/0000-0001-9898-1430","observed_orcids":["https://orcid.org/0000-0001-9898-1430"]},"institutions":[{"id":"https://openalex.org/I1295499534","display_name":"Seattle Children's Hospital","ror":"https://ror.org/01njes783","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295499534"]},{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Karen Murray","raw_affiliation_strings":["Department of Pediatrics, Seattle Children's Hospital and Regional Medical Center, University of Washington, 4800 Sand Point Way NE, Seattle, Washington, USA","Department of Pediatrics, Seattle Children's Hospital and Regional Medical Center, University of Washington, Washington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Seattle Children's Hospital and Regional Medical Center, University of Washington, 4800 Sand Point Way NE, Seattle, Washington, USA","institution_ids":["https://openalex.org/I1295499534","https://openalex.org/I201448701"]},{"raw_affiliation_string":"Department of Pediatrics, Seattle Children's Hospital and Regional Medical Center, University of Washington, Washington, USA","institution_ids":["https://openalex.org/I1295499534","https://openalex.org/I201448701"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5103615124","display_name":"Dennis L. Christie","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I1295499534","display_name":"Seattle Children's Hospital","ror":"https://ror.org/01njes783","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I1295499534"]},{"id":"https://openalex.org/I201448701","display_name":"University of Washington","ror":"https://ror.org/00cvxb145","country_code":"US","type":"education","lineage":["https://openalex.org/I201448701"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dennis Christie","raw_affiliation_strings":["Department of Pediatrics, Seattle Children's Hospital and Regional Medical Center, University of Washington, 4800 Sand Point Way NE, Seattle, Washington, USA","Department of Pediatrics, Seattle Children's Hospital and Regional Medical Center, University of Washington, Washington, USA"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pediatrics, Seattle Children's Hospital and Regional Medical Center, University of Washington, 4800 Sand Point Way NE, Seattle, Washington, USA","institution_ids":["https://openalex.org/I1295499534","https://openalex.org/I201448701"]},{"raw_affiliation_string":"Department of Pediatrics, Seattle Children's Hospital and Regional Medical Center, University of Washington, Washington, USA","institution_ids":["https://openalex.org/I1295499534","https://openalex.org/I201448701"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":2,"corresponding_author_ids":["https://openalex.org/A5049522610"],"corresponding_institution_ids":["https://openalex.org/I1295499534","https://openalex.org/I201448701"],"apc_list":{"value":3190,"currency":"USD","value_usd":3190},"apc_paid":{"value":3190,"currency":"USD","value_usd":3190},"fwci":0.1779,"has_fulltext":true,"cited_by_count":5,"citation_normalized_percentile":{"value":0.52792116,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":89,"max":94},"biblio":{"volume":"4","issue":"1","first_page":"26","last_page":"26"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.7397000193595886,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10134","display_name":"Inflammatory Bowel Disease","score":0.7397000193595886,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.13259999454021454,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11625","display_name":"Abdominal vascular conditions and treatments","score":0.02250000089406967,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/disseminated-intravascular-coagulation","display_name":"disseminated intravascular coagulation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/inflammatory-bowel-disease","display_name":"inflammatory bowel disease","score":0.8820000290870667},{"id":"https://openalex.org/keywords/hypercoagulability","display_name":"hypercoagulability","score":0.906000018119812},{"id":"https://openalex.org/keywords/hematuria","display_name":"hematuria","score":0.8939999938011169},{"id":"https://openalex.org/keywords/hematochezia","display_name":"hematochezia","score":0.9850000143051147},{"id":"https://openalex.org/keywords/intravenous-corticosteroids","display_name":"intravenous corticosteroids","score":0.8370000123977661},{"id":"https://openalex.org/keywords/pediatric-inflammatory-bowel-disease","display_name":"pediatric inflammatory bowel disease","score":0.7160000205039978}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9295564889907837},{"id":"https://openalex.org/C2778734968","wikidata":"https://www.wikidata.org/wiki/Q823027","display_name":"Disseminated intravascular coagulation","level":2,"score":0.872028112411499},{"id":"https://openalex.org/C2779936836","wikidata":"https://www.wikidata.org/wiki/Q890200","display_name":"Coagulopathy","level":2,"score":0.7063183784484863},{"id":"https://openalex.org/C2780479503","wikidata":"https://www.wikidata.org/wiki/Q1477","display_name":"Ulcerative colitis","level":3,"score":0.6194744110107422},{"id":"https://openalex.org/C2776611563","wikidata":"https://www.wikidata.org/wiki/Q588321","display_name":"Toxic megacolon","level":4,"score":0.4572888910770416},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.4344542622566223},{"id":"https://openalex.org/C90924648","wikidata":"https://www.wikidata.org/wiki/Q120569","display_name":"Gastroenterology","level":1,"score":0.3813284635543823},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.3398987054824829},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.09432259202003479}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001745","descriptor_name":"Urinary Bladder Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D003093","descriptor_name":"Colitis, Ulcerative","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D004211","descriptor_name":"Disseminated Intravascular Coagulation","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D006406","descriptor_name":"Hematoma","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1186/1471-230x-4-26","doi":"https://doi.org/10.1186/1471-230x-4-26","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-230x-4-26","pdf_url":"https://link.springer.com/content/pdf/10.1186/1471-230X-4-26.pdf","source":{"id":"https://openalex.org/S180811554","display_name":"BMC Gastroenterology","issn_l":"1471-230X","issn":["1471-230X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Gastroenterology","raw_type":"journal-article"},{"id":"pmh:oai:pubmedcentral.nih.gov:526371","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/526371","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Gastroenterol","raw_type":"Text"},{"id":"pmid:15471542","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/15471542","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC gastroenterology","raw_type":"Case Reports"},{"id":"pmh:oai:doaj.org/article:82a89e6de0554864bf44d95636be1195","doi":null,"is_oa":false,"landing_page_url":"https://doaj.org/article/82a89e6de0554864bf44d95636be1195","pdf_url":null,"source":{"id":"https://openalex.org/S4306401280","display_name":"DOAJ (DOAJ: Directory of Open Access Journals)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"BMC Gastroenterology, Vol 4, Iss 1, p 26 (2004)","raw_type":"article"}],"best_oa_location":{"id":"doi:10.1186/1471-230x-4-26","doi":"https://doi.org/10.1186/1471-230x-4-26","is_oa":true,"landing_page_url":"https://doi.org/10.1186/1471-230x-4-26","pdf_url":"https://link.springer.com/content/pdf/10.1186/1471-230X-4-26.pdf","source":{"id":"https://openalex.org/S180811554","display_name":"BMC Gastroenterology","issn_l":"1471-230X","issn":["1471-230X"],"is_oa":true,"is_in_doaj":true,"is_core":true,"listed_in":["cwts-core","doaj","dongbi-d","doyens","jufo-1","ki-jl-1","medline","norway-1","oarl","poland-100","russia-white-list-3","vabb-shw"],"host_organization":"https://openalex.org/P4310320256","host_organization_name":"BioMed Central","host_organization_lineage":["https://openalex.org/P4310320256","https://openalex.org/P4310319965"],"host_organization_lineage_names":["BioMed Central","Springer Nature"],"type":"journal"},"license":"cc-by","license_id":"https://openalex.org/licenses/cc-by","version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"BMC Gastroenterology","raw_type":"journal-article"},"sustainable_development_goals":[{"score":1.0,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"sustainable_development_goals_aurora":[{"score":0.8199999928474426,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[{"display_name":"Case Report","id":"https://openalex.org/study-designs/case-report"}],"awards":[],"funders":[],"has_content":{"grobid_xml":true,"pdf":true},"content_urls":{"pdf":"https://content.openalex.org/works/W1487705489.pdf","grobid_xml":"https://content.openalex.org/works/W1487705489.grobid-xml"},"referenced_works_count":18,"referenced_works":["https://openalex.org/W1983321643","https://openalex.org/W1987440738","https://openalex.org/W2013351709","https://openalex.org/W2050371307","https://openalex.org/W2070132802","https://openalex.org/W2070424138","https://openalex.org/W2070737656","https://openalex.org/W2081187824","https://openalex.org/W2100176961","https://openalex.org/W2132748540","https://openalex.org/W2136971812","https://openalex.org/W2155279047","https://openalex.org/W2295729920","https://openalex.org/W2325892862","https://openalex.org/W2326474248","https://openalex.org/W2335209382","https://openalex.org/W2409377436","https://openalex.org/W2411367595"],"related_works":["https://openalex.org/W2409377436","https://openalex.org/W2415427558","https://openalex.org/W7100684618","https://openalex.org/W2912778530","https://openalex.org/W2122247332","https://openalex.org/W2396762726","https://openalex.org/W4412020904","https://openalex.org/W2977404049","https://openalex.org/W2256443507","https://openalex.org/W4417171106"],"abstract_inverted_index":{"BACKGROUND:":[0],"Disorders":[1],"of":[2,40,50,55,64,92,128,137,146,162,180,192,215,248],"coagulation":[3,30,35,75,184,230,257],"have":[4,24,28],"long":[5],"been":[6,25,70],"associated":[7,71,165,218,231],"with":[8,17,72,78,89,98,166,178,219,232],"inflammatory":[9],"bowel":[10],"disease.":[11],"Children,":[12],"as":[13,15,141,143],"well":[14,142],"adults,":[16],"both":[18],"active":[19],"and":[20,31,52,82,102,135,151,190,258],"inactive":[21],"ulcerative":[22,95,220,233,250],"colitis":[23,68,96,221,234,251],"found":[26],"to":[27,46,60,207,225,238],"abnormal":[29],"fibrinolysis.":[32],"Disseminated":[33],"intravascular":[34,74,108,168,183,194,210,229,256],"arises":[36],"from":[37,223],"an":[38,47,249],"overwhelming":[39],"the":[41,56,129,138,147,181],"haemostatic":[42],"regulatory":[43],"mechanisms":[44],"leading":[45],"excessive":[48],"generation":[49],"thrombin":[51],"a":[53,90,132,160,246,259],"failure":[54],"normal":[57],"inhibitory":[58],"pathways":[59],"prevent":[61],"systemic":[62],"effects":[63],"this":[65],"enzyme.":[66],"Ulcerative":[67],"has":[69],"disseminated":[73,107,167,182,193,209,228,255],"in":[76,254],"conjunction":[77],"septicemia,":[79,239],"toxic":[80,240],"megacolon":[81,241],"surgery.":[83],"CASE":[84],"PRESENTATION:":[85],"A":[86,123,199],"fourteen-year-old":[87],"boy":[88],"history":[91],"poorly":[93],"controlled":[94],"presented":[97],"nonbilious":[99],"emesis,":[100],"hematochezia,":[101],"hematuria.":[103],"Laboratory":[104],"workup":[105,119,202],"revealed":[106,131,203],"coagulation.":[109,169,211],"He":[110],"was":[111,171],"placed":[112],"on":[113,173],"triple":[114],"antibiotics":[115],"therapy.":[116],"An":[117],"infectious":[118,201],"came":[120],"back":[121],"negative.":[122],"computerized":[124],"tomography":[125],"(CT)":[126],"scan":[127],"abdomen":[130],"marked":[133],"thickening":[134,145],"irregularity":[136],"bladder":[139,260],"wall":[140,144],"rectosigmoid,":[148],"ascending,":[149],"transverse,":[150],"descending":[152],"colon.":[153],"Patient's":[154],"clinical":[155],"status":[156],"remained":[157],"stable":[158],"despite":[159],"worsening":[161],"laboratory":[163,185],"values":[164,186],"Patient":[170],"begun":[172],"high":[174],"dose":[175],"intravenous":[176],"steroids":[177],"improvement":[179],"within":[187,196],"12":[188],"hours":[189],"resolution":[191],"coagulopathy":[195],"4":[197],"days.":[198],"thorough":[200],"no":[204],"other":[205],"causes":[206],"his":[208],"CONCLUSIONS:":[212],"The":[213],"spectrum":[214],"hypercoagulable":[216],"states":[217],"varies":[222],"mild":[224],"severe.":[226],"Although":[227],"is":[235],"usually":[236],"related":[237],"or":[242],"surgery,":[243],"we":[244],"present":[245],"case":[247],"flare":[252],"resulting":[253],"hematoma.":[261]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2018,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}