{"id":"https://openalex.org/W1487308593","doi":null,"title":"A novel topical ingredient derived from seaweed significantly reduces symptoms of acne vulgaris: a general literature review.","display_name":"A novel topical ingredient derived from seaweed significantly reduces symptoms of acne vulgaris: a general literature review.","publication_year":2013,"publication_date":"2013-05-01","ids":{"openalex":"https://openalex.org/W1487308593","mag":"1487308593","pmid":"https://pubmed.ncbi.nlm.nih.gov/23752036"},"language":"en","primary_location":{"id":"pmid:23752036","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23752036","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of cosmetic science","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5067626176","display_name":"C. H. S. Ruxton","orcid":"https://orcid.org/0000-0002-0132-6331","observed_orcids":["https://orcid.org/0000-0002-0132-6331"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Carrie H S Ruxton","raw_affiliation_strings":["Nutrition Communications, Cupar, United Kingdom. carrie@nutrition-communications.com"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Nutrition Communications, Cupar, United Kingdom. carrie@nutrition-communications.com","institution_ids":[]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039182505","display_name":"Gill Jenkins","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Gill Jenkins","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.0562,"has_fulltext":false,"cited_by_count":11,"citation_normalized_percentile":{"value":0.74615704,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"64","issue":"3","first_page":"219","last_page":"26"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11553","display_name":"Acne and Rosacea Treatments and Effects","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11553","display_name":"Acne and Rosacea Treatments and Effects","score":0.9980000257492065,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11390","display_name":"Seaweed-derived Bioactive Compounds","score":0.00139999995008111,"subfield":{"id":"https://openalex.org/subfields/1104","display_name":"Aquatic Science"},"field":{"id":"https://openalex.org/fields/11","display_name":"Agricultural and Biological Sciences"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10837","display_name":"Dermatology and Skin Diseases","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2708","display_name":"Dermatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/acne-vulgaris","display_name":"acne","score":0.996999979019165},{"id":"https://openalex.org/keywords/laminaria-digitata","display_name":"Laminaria digitata","score":0.984000027179718},{"id":"https://openalex.org/keywords/zinc-complexes","display_name":"zinc complexes","score":0.7559999823570251},{"id":"https://openalex.org/keywords/topical-therapy","display_name":"topical treatment","score":0.7139999866485596},{"id":"https://openalex.org/keywords/sebum-secretion","display_name":"sebum production","score":0.968999981880188},{"id":"https://openalex.org/keywords/cutibacterium-acnes","display_name":"Propionibacterium acnes","score":0.9940000176429749},{"id":"https://openalex.org/keywords/marine-polysaccharides","display_name":"marine polysaccharides","score":0.8159999847412109}],"concepts":[{"id":"https://openalex.org/C2777345499","wikidata":"https://www.wikidata.org/wiki/Q1093337","display_name":"Laminaria digitata","level":3,"score":0.7383955717086792},{"id":"https://openalex.org/C2777673923","wikidata":"https://www.wikidata.org/wiki/Q79928","display_name":"Acne","level":2,"score":0.7084695100784302},{"id":"https://openalex.org/C2777450936","wikidata":"https://www.wikidata.org/wiki/Q310748","display_name":"Laminaria","level":3,"score":0.5929647088050842},{"id":"https://openalex.org/C16005928","wikidata":"https://www.wikidata.org/wiki/Q171171","display_name":"Dermatology","level":1,"score":0.5157520771026611},{"id":"https://openalex.org/C45904493","wikidata":"https://www.wikidata.org/wiki/Q912807","display_name":"Active ingredient","level":2,"score":0.4943971633911133},{"id":"https://openalex.org/C168563851","wikidata":"https://www.wikidata.org/wiki/Q1436668","display_name":"Randomized controlled trial","level":2,"score":0.46294841170310974},{"id":"https://openalex.org/C556039675","wikidata":"https://www.wikidata.org/wiki/Q771035","display_name":"Traditional medicine","level":1,"score":0.46003517508506775},{"id":"https://openalex.org/C2779900937","wikidata":"https://www.wikidata.org/wiki/Q2442109","display_name":"Propionibacterium acnes","level":3,"score":0.4301919937133789},{"id":"https://openalex.org/C559758991","wikidata":"https://www.wikidata.org/wiki/Q37868","display_name":"Algae","level":2,"score":0.41565725207328796},{"id":"https://openalex.org/C2780589914","wikidata":"https://www.wikidata.org/wiki/Q10675206","display_name":"Ingredient","level":2,"score":0.41291409730911255},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3997018337249756},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3613869845867157},{"id":"https://openalex.org/C31903555","wikidata":"https://www.wikidata.org/wiki/Q1637030","display_name":"Food science","level":1,"score":0.2805424630641937},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.2709083557128906},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.2402147352695465},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.17492446303367615}],"mesh":[{"descriptor_ui":"D000152","descriptor_name":"Acne Vulgaris","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D004311","descriptor_name":"Double-Blind Method","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010919","descriptor_name":"Placebos","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010936","descriptor_name":"Plant Extracts","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":true},{"descriptor_ui":"D012624","descriptor_name":"Seaweed","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":true},{"descriptor_ui":"D016032","descriptor_name":"Randomized Controlled Trials as Topic","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D019317","descriptor_name":"Evidence-Based Medicine","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:23752036","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23752036","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of cosmetic science","raw_type":"Journal Article"},{"id":"mag:1487308593","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/23752036","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2166911109","https://openalex.org/W2464423087","https://openalex.org/W2501919527","https://openalex.org/W2408186967","https://openalex.org/W2114844954","https://openalex.org/W4412830755","https://openalex.org/W4406083341","https://openalex.org/W2988571091","https://openalex.org/W3085403175","https://openalex.org/W2437523994"],"abstract_inverted_index":{"Currently,":[0],"benzoyl":[1],"peroxide,":[2],"antibiotics,":[3],"and":[4,56,85,110],"retinoids":[5],"are":[6,46],"the":[7,37,50],"mainstay":[8],"topical":[9],"treatments":[10],"for":[11],"acne":[12,101],"vulgaris.":[13],"However,":[14],"potential":[15],"benefits":[16],"may":[17],"be":[18,83],"offered":[19],"by":[20],"natural,":[21],"marine-derived":[22],"ingredients,":[23],"such":[24],"as":[25],"those":[26,47],"derived":[27,48],"from":[28,49,72],"brown":[29],"seaweed":[30,59],"(Laminaria":[31],"digitata).":[32],"This":[33],"article":[34],"will":[35,81],"review":[36],"available":[38],"literature":[39],"on":[40],"two":[41],"ingredients;":[42],"\"seaweed":[43],"oligosaccharides,\"":[44],"which":[45],"polysaccharide":[51],"membrane":[52],"of":[53,100,106,112],"Laminaria":[54],"digitata,":[55],"a":[57,73],"novel":[58],"oligosaccharide-zinc":[60],"complex":[61],"(SOZC)":[62],"(Phycosaccharide":[63],"AC,":[64],"The":[65,89],"Mentholatum":[66],"Company,":[67],"East":[68],"Kilbride,":[69],"UK).":[70],"Findings":[71],"recent":[74],"double-blind,":[75],"placebo-controlled,":[76],"randomized":[77],"clinical":[78],"trial":[79],"(RCT)":[80],"also":[82],"reported":[84],"likely":[86],"mechanisms":[87],"discussed.":[88],"findings":[90],"taken":[91],"together":[92],"suggest":[93],"that":[94],"SOZC":[95],"can":[96],"significantly":[97],"ameliorate":[98],"symptoms":[99],"vulgaris,":[102],"particularly":[103],"in":[104],"terms":[105],"reducing":[107],"sebum":[108],"production":[109],"populations":[111],"Propionibacterium":[113],"acnes.":[114]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":1},{"year":2022,"cited_by_count":2},{"year":2019,"cited_by_count":1},{"year":2017,"cited_by_count":1},{"year":2014,"cited_by_count":3}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}