{"id":"https://openalex.org/W1486892708","doi":"https://doi.org/10.1046/j.1471-4159.2003.01519.x","title":"Specific interactions of neuronal focal adhesion kinase isoforms with Src kinases and amphiphysin","display_name":"Specific interactions of neuronal focal adhesion kinase isoforms with Src kinases and amphiphysin","publication_year":2003,"publication_date":"2003-01-01","ids":{"openalex":"https://openalex.org/W1486892708","doi":"https://doi.org/10.1046/j.1471-4159.2003.01519.x","mag":"1486892708","pmid":"https://pubmed.ncbi.nlm.nih.gov/12558988"},"language":"en","primary_location":{"id":"doi:10.1046/j.1471-4159.2003.01519.x","doi":"https://doi.org/10.1046/j.1471-4159.2003.01519.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.1471-4159.2003.01519.x","pdf_url":null,"source":{"id":"https://openalex.org/S135837084","display_name":"Journal of Neurochemistry","issn_l":"0022-3042","issn":["0022-3042","1471-4159"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurochemistry","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5057699430","display_name":"Samantha Messina","orcid":"https://orcid.org/0000-0003-2185-8236","observed_orcids":["https://orcid.org/0000-0003-2185-8236"]},"institutions":[{"id":"https://openalex.org/I83816512","display_name":"University of Genoa","ror":"https://ror.org/0107c5v14","country_code":"IT","type":"education","lineage":["https://openalex.org/I83816512"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Samantha Messina","raw_affiliation_strings":["Department of Experimental Medicine, Section of Human Physiology, University of Genova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Medicine, Section of Human Physiology, University of Genova, Italy","institution_ids":["https://openalex.org/I83816512"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044611405","display_name":"Franco Onofri","orcid":"https://orcid.org/0000-0001-5595-0036","observed_orcids":["https://orcid.org/0000-0001-5595-0036"]},"institutions":[{"id":"https://openalex.org/I83816512","display_name":"University of Genoa","ror":"https://ror.org/0107c5v14","country_code":"IT","type":"education","lineage":["https://openalex.org/I83816512"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Franco Onofri","raw_affiliation_strings":["Department of Experimental Medicine, Section of Human Physiology, University of Genova, Genova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Medicine, Section of Human Physiology, University of Genova, Genova, Italy","institution_ids":["https://openalex.org/I83816512"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5081106994","display_name":"Lucilla Bongiorno\u2010Borbone","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210137787","display_name":"Institut du Fer \u00e0 Moulin","ror":"https://ror.org/03x9frp33","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210137787","https://openalex.org/I4405255169"]},{"id":"https://openalex.org/I4405264447","display_name":"Universit\u00e9 Pierre-et-Marie-Curie","ror":"https://ror.org/01yvrd251","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081","https://openalex.org/I4405264447"]},{"id":"https://openalex.org/I83816512","display_name":"University of Genoa","ror":"https://ror.org/0107c5v14","country_code":"IT","type":"education","lineage":["https://openalex.org/I83816512"]}],"countries":["FR","IT"],"is_corresponding":false,"raw_author_name":"Lucilla Bongiorno\u2010Borbone","raw_affiliation_strings":["Department of Experimental Medicine, Section of Human Physiology, University of Genova, Genova, Italy","INSERM/UPMC U536, Institut du Fer \u00e0 Moulin, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Medicine, Section of Human Physiology, University of Genova, Genova, Italy","institution_ids":["https://openalex.org/I83816512"]},{"raw_affiliation_string":"INSERM/UPMC U536, Institut du Fer \u00e0 Moulin, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210137787","https://openalex.org/I4405264447"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057013395","display_name":"Silvia Gioved\u00ec","orcid":"https://orcid.org/0000-0001-7949-4274","observed_orcids":["https://orcid.org/0000-0001-7949-4274"]},"institutions":[{"id":"https://openalex.org/I83816512","display_name":"University of Genoa","ror":"https://ror.org/0107c5v14","country_code":"IT","type":"education","lineage":["https://openalex.org/I83816512"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Silvia Gioved\u00ec","raw_affiliation_strings":["Department of Experimental Medicine, Section of Human Physiology, University of Genova, Genova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Medicine, Section of Human Physiology, University of Genova, Genova, Italy","institution_ids":["https://openalex.org/I83816512"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5089355174","display_name":"Flavia Valtorta","orcid":"https://orcid.org/0000-0001-9556-4746","observed_orcids":["https://orcid.org/0000-0001-9556-4746"]},"institutions":[{"id":"https://openalex.org/I4210133214","display_name":"IRCCS Ospedale San Raffaele","ror":"https://ror.org/039zxt351","country_code":"IT","type":"healthcare","lineage":["https://openalex.org/I4210133214","https://openalex.org/I4210153126"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Flavia Valtorta","raw_affiliation_strings":["Department of Neuroscience, San Raffaele Scientific Institute, Milano, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Neuroscience, San Raffaele Scientific Institute, Milano, Italy","institution_ids":["https://openalex.org/I4210133214"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5065550629","display_name":"Jean\u2010Antoine Girault","orcid":"https://orcid.org/0000-0002-7900-1705","observed_orcids":["https://orcid.org/0000-0002-7900-1705"]},"institutions":[{"id":"https://openalex.org/I154526488","display_name":"Inserm","ror":"https://ror.org/02vjkv261","country_code":"FR","type":"government","lineage":["https://openalex.org/I154526488"]},{"id":"https://openalex.org/I4210137787","display_name":"Institut du Fer \u00e0 Moulin","ror":"https://ror.org/03x9frp33","country_code":"FR","type":"facility","lineage":["https://openalex.org/I1294671590","https://openalex.org/I154526488","https://openalex.org/I39804081","https://openalex.org/I4210137787","https://openalex.org/I4405255169"]},{"id":"https://openalex.org/I4405264447","display_name":"Universit\u00e9 Pierre-et-Marie-Curie","ror":"https://ror.org/01yvrd251","country_code":"FR","type":"education","lineage":["https://openalex.org/I39804081","https://openalex.org/I4405264447"]}],"countries":["FR"],"is_corresponding":false,"raw_author_name":"Jean\u2010Antoine Girault","raw_affiliation_strings":["INSERM/UPMC U536, Institut du Fer \u00e0 Moulin, Paris, France"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"INSERM/UPMC U536, Institut du Fer \u00e0 Moulin, Paris, France","institution_ids":["https://openalex.org/I154526488","https://openalex.org/I4210137787","https://openalex.org/I4405264447"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5073562468","display_name":"Fabio Benfenati","orcid":"https://orcid.org/0000-0002-0653-8368","observed_orcids":["https://orcid.org/0000-0002-0653-8368"]},"institutions":[{"id":"https://openalex.org/I83816512","display_name":"University of Genoa","ror":"https://ror.org/0107c5v14","country_code":"IT","type":"education","lineage":["https://openalex.org/I83816512"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Fabio Benfenati","raw_affiliation_strings":["Department of Experimental Medicine, Section of Human Physiology, University of Genova, Genova, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Experimental Medicine, Section of Human Physiology, University of Genova, Genova, Italy","institution_ids":["https://openalex.org/I83816512"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":5,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":5330,"currency":"USD","value_usd":5330},"apc_paid":null,"fwci":1.6444,"has_fulltext":false,"cited_by_count":29,"citation_normalized_percentile":{"value":0.7978529,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"84","issue":"2","first_page":"253","last_page":"265"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.49149999022483826,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10831","display_name":"Cell Adhesion Molecules Research","score":0.49149999022483826,"subfield":{"id":"https://openalex.org/subfields/2723","display_name":"Immunology and Allergy"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10169","display_name":"Protein Kinase Regulation and GTPase Signaling","score":0.47920000553131104,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10077","display_name":"Neuroscience and Neuropharmacology Research","score":0.009999999776482582,"subfield":{"id":"https://openalex.org/subfields/2804","display_name":"Cellular and Molecular Neuroscience"},"field":{"id":"https://openalex.org/fields/28","display_name":"Neuroscience"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/focal-adhesion-kinase","display_name":"focal adhesion kinase","score":0.9869999885559082},{"id":"https://openalex.org/keywords/src-family-kinases","display_name":"Src family kinases","score":0.8709999918937683},{"id":"https://openalex.org/keywords/src-kinase","display_name":"Src kinase","score":0.9309999942779541},{"id":"https://openalex.org/keywords/sh3-domain-binding","display_name":"SH3 domain binding","score":0.7110000252723694},{"id":"https://openalex.org/keywords/sh2-domain","display_name":"SH2 domain","score":0.777999997138977},{"id":"https://openalex.org/keywords/amphiphysin","display_name":"amphiphysin","score":0.9430000185966492},{"id":"https://openalex.org/keywords/proline-rich-region","display_name":"proline-rich region","score":0.7239999771118164},{"id":"https://openalex.org/keywords/neuronal-signaling","display_name":"neuronal signaling","score":0.5170000195503235},{"id":"https://openalex.org/keywords/endocytosis","display_name":"endocytosis","score":0.8339999914169312},{"id":"https://openalex.org/keywords/synaptosomes","display_name":"synaptosomes","score":0.8569999933242798},{"id":"https://openalex.org/keywords/membrane-trafficking","display_name":"membrane trafficking","score":0.7549999952316284},{"id":"https://openalex.org/keywords/neurotransmitter-signaling","display_name":"neurotransmitter signaling","score":0.5450000166893005},{"id":"https://openalex.org/keywords/actin-cytoskeleton","display_name":"actin cytoskeleton","score":0.9010000228881836}],"concepts":[{"id":"https://openalex.org/C196347352","wikidata":"https://www.wikidata.org/wiki/Q24771787","display_name":"SH3 domain","level":4,"score":0.9129998683929443},{"id":"https://openalex.org/C2780976139","wikidata":"https://www.wikidata.org/wiki/Q14906081","display_name":"Amphiphysin","level":5,"score":0.8645211458206177},{"id":"https://openalex.org/C108636557","wikidata":"https://www.wikidata.org/wiki/Q21109354","display_name":"Proto-oncogene tyrosine-protein kinase Src","level":3,"score":0.8293693661689758},{"id":"https://openalex.org/C37686147","wikidata":"https://www.wikidata.org/wiki/Q423628","display_name":"FYN","level":4,"score":0.6522671580314636},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.6339854001998901},{"id":"https://openalex.org/C197153747","wikidata":"https://www.wikidata.org/wiki/Q24780316","display_name":"SH2 domain","level":4,"score":0.6143327355384827},{"id":"https://openalex.org/C151166631","wikidata":"https://www.wikidata.org/wiki/Q904514","display_name":"Focal adhesion","level":3,"score":0.5949133038520813},{"id":"https://openalex.org/C2776000893","wikidata":"https://www.wikidata.org/wiki/Q14906154","display_name":"Cortactin","level":4,"score":0.5519247055053711},{"id":"https://openalex.org/C175818844","wikidata":"https://www.wikidata.org/wiki/Q2463389","display_name":"LYN","level":4,"score":0.5338280200958252},{"id":"https://openalex.org/C42362537","wikidata":"https://www.wikidata.org/wiki/Q87099740","display_name":"Tyrosine kinase","level":3,"score":0.4844053387641907},{"id":"https://openalex.org/C177917778","wikidata":"https://www.wikidata.org/wiki/Q14905188","display_name":"GRB2","level":4,"score":0.45877063274383545},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4546731412410736},{"id":"https://openalex.org/C184235292","wikidata":"https://www.wikidata.org/wiki/Q421851","display_name":"Kinase","level":2,"score":0.4004484713077545},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3797107934951782},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3138728737831116},{"id":"https://openalex.org/C62478195","wikidata":"https://www.wikidata.org/wiki/Q828130","display_name":"Signal transduction","level":2,"score":0.31111058592796326},{"id":"https://openalex.org/C156407911","wikidata":"https://www.wikidata.org/wiki/Q420160","display_name":"Dynamin","level":4,"score":0.21525052189826965},{"id":"https://openalex.org/C142669718","wikidata":"https://www.wikidata.org/wiki/Q154626","display_name":"Cytoskeleton","level":3,"score":0.1904551088809967},{"id":"https://openalex.org/C28005876","wikidata":"https://www.wikidata.org/wiki/Q189814","display_name":"Endocytosis","level":3,"score":0.1349671483039856},{"id":"https://openalex.org/C170493617","wikidata":"https://www.wikidata.org/wiki/Q208467","display_name":"Receptor","level":2,"score":0.11906969547271729},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001923","descriptor_name":"Brain Chemistry","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D009419","descriptor_name":"Nerve Tissue Proteins","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D009419","descriptor_name":"Nerve Tissue Proteins","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000201","qualifier_name":"enzymology","is_major_topic":false},{"descriptor_ui":"D009474","descriptor_name":"Neurons","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011233","descriptor_name":"Precipitin Tests","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011485","descriptor_name":"Protein Binding","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D011505","descriptor_name":"Protein-Tyrosine Kinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D011505","descriptor_name":"Protein-Tyrosine Kinases","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D013574","descriptor_name":"Synaptosomes","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D013574","descriptor_name":"Synaptosomes","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D015151","descriptor_name":"Immunoblotting","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018909","descriptor_name":"src Homology Domains","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D019061","descriptor_name":"src-Family Kinases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D019061","descriptor_name":"src-Family Kinases","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D019556","descriptor_name":"COS Cells","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D020033","descriptor_name":"Protein Isoforms","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051416","descriptor_name":"Focal Adhesion Protein-Tyrosine Kinases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051417","descriptor_name":"Focal Adhesion Kinase 1","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":5,"locations":[{"id":"doi:10.1046/j.1471-4159.2003.01519.x","doi":"https://doi.org/10.1046/j.1471-4159.2003.01519.x","is_oa":false,"landing_page_url":"https://doi.org/10.1046/j.1471-4159.2003.01519.x","pdf_url":null,"source":{"id":"https://openalex.org/S135837084","display_name":"Journal of Neurochemistry","issn_l":"0022-3042","issn":["0022-3042","1471-4159"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","dongbi-d","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Neurochemistry","raw_type":"journal-article"},{"id":"pmid:12558988","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/12558988","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of neurochemistry","raw_type":"Journal Article"},{"id":"pmh:oai:iris.unicas.it:11580/10768","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11580/10768","pdf_url":null,"source":{"id":"https://openalex.org/S7407055277","display_name":"Archivio Istituzionale della Ricerca - Universit\u00e0 degli Studi di Cassino","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:iris.unige.it:11567/251364","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/11567/251364","pdf_url":null,"source":{"id":"https://openalex.org/S4377196291","display_name":"CINECA IRIS Institutial Research Information System (University of Genoa)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I83816512","host_organization_name":"University of Genoa","host_organization_lineage":["https://openalex.org/I83816512"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"info:eu-repo/semantics/article"},{"id":"pmh:oai:iris.unisr.it:20.500.11768/2922","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/20.500.11768/2922","pdf_url":null,"source":{"id":"https://openalex.org/S7407055348","display_name":"Archivio Istituzionale della Ricerca - Universit\u00e0 Vita-Salute San Raffaele","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"info:eu-repo/semantics/article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[],"funders":[{"id":"https://openalex.org/F4320323054","display_name":"Associazione Italiana per la Ricerca sul Cancro","ror":"https://ror.org/02g2x7380"}],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":57,"referenced_works":["https://openalex.org/W1501756998","https://openalex.org/W1514018207","https://openalex.org/W1785533687","https://openalex.org/W1969352183","https://openalex.org/W1972910989","https://openalex.org/W1974195264","https://openalex.org/W1988452929","https://openalex.org/W1991015390","https://openalex.org/W1998232144","https://openalex.org/W2001977579","https://openalex.org/W2002038355","https://openalex.org/W2005216725","https://openalex.org/W2009623574","https://openalex.org/W2014914858","https://openalex.org/W2021581599","https://openalex.org/W2031188680","https://openalex.org/W2034710767","https://openalex.org/W2035429354","https://openalex.org/W2041541858","https://openalex.org/W2043761739","https://openalex.org/W2047131896","https://openalex.org/W2047841570","https://openalex.org/W2054779757","https://openalex.org/W2055455533","https://openalex.org/W2060057909","https://openalex.org/W2063014852","https://openalex.org/W2063118638","https://openalex.org/W2063259786","https://openalex.org/W2069246118","https://openalex.org/W2074031136","https://openalex.org/W2074382485","https://openalex.org/W2076364749","https://openalex.org/W2076636373","https://openalex.org/W2076649773","https://openalex.org/W2078897717","https://openalex.org/W2080579127","https://openalex.org/W2087799476","https://openalex.org/W2088760800","https://openalex.org/W2088847457","https://openalex.org/W2090501101","https://openalex.org/W2094389040","https://openalex.org/W2100837269","https://openalex.org/W2105356859","https://openalex.org/W2105417881","https://openalex.org/W2105512558","https://openalex.org/W2124757700","https://openalex.org/W2131734392","https://openalex.org/W2133263385","https://openalex.org/W2136203552","https://openalex.org/W2137985055","https://openalex.org/W2146529473","https://openalex.org/W2147177984","https://openalex.org/W2148560401","https://openalex.org/W2151766851","https://openalex.org/W2160625381","https://openalex.org/W2172158217","https://openalex.org/W2314225431"],"related_works":["https://openalex.org/W1514018207","https://openalex.org/W7025038633","https://openalex.org/W2063014852","https://openalex.org/W2053582875","https://openalex.org/W2043761739","https://openalex.org/W2001050126","https://openalex.org/W1966708072","https://openalex.org/W2056577444","https://openalex.org/W2079163466","https://openalex.org/W2012799785"],"abstract_inverted_index":{"Focal":[0],"adhesion":[1],"kinase":[2,8],"(FAK)":[3],"is":[4],"a":[5,95,111,123,155,177],"non-receptor":[6],"tyrosine":[7],"that":[9],"activates":[10],"Src":[11,119,197],"family":[12],"kinases":[13,198],"via":[14],"SH2-":[15],"and":[16,26,39,55,84,106,110,154,196,199,214],"SH3-mediated":[17],"interactions.":[18],"Specific":[19],"FAK":[20,195,209,216],"isoforms":[21,42],"(FAK+),":[22],"responsive":[23],"to":[24,65,103,117,159,181,208],"depolarization":[25],"neurotransmitters,":[27],"are":[28],"enriched":[29],"in":[30,98,114,172,211,217,223],"neurons.":[31],"We":[32],"analyzed":[33],"the":[34,56,66,99,104,115,118,126,135,140,151,162,182,190,200,204,212,218],"interactions":[35],"of":[36,52,69,89,101,125,129,144,150,168,176,184,194,203,220],"endogenous":[37],"FAK+":[38,41,62,102],"recombinant":[40],"containing":[43],"amino":[44],"acid":[45],"insertions":[46],"(boxes":[47],"6,7,28)":[48],"with":[49,94,134],"an":[50,166],"array":[51],"SH3":[53,67,108,137],"domains":[54,68],"c-Src":[57,70,105],"SH2/SH3":[58],"domain":[59],"tandem.":[60],"Endogenous":[61],"bound":[63],"specifically":[64],"(but":[71],"not":[72],"n-Src),":[73],"Fyn,":[74],"Yes,":[75],"phosphtidylinositol-3":[76],"kinase,":[77],"amphiphysin":[78,80,136],"II,":[79],"I,":[81],"phospholipase":[82],"Cgamma":[83],"NH2-terminal":[85],"Grb2.":[86],"The":[87,131,186],"inclusion":[88],"boxes":[90],"6,7":[91],"was":[92,146,170],"associated":[93],"significant":[96,112],"decrease":[97],"binding":[100,116],"Fyn":[107],"domains,":[109],"increase":[113],"SH2":[120],"domain,":[121,138],"as":[122],"consequence":[124],"higher":[127],"phosphorylation":[128],"Tyr-397.":[130],"novel":[132],"interaction":[133],"involving":[139],"COOH-terminal":[141],"proline-rich":[142,178],"region":[143],"FAK,":[145],"confirmed":[147],"by":[148],"coimmunoprecipitation":[149],"two":[152],"proteins":[153],"closely":[156],"similar":[157],"response":[158],"stimuli":[160],"affecting":[161],"actin":[163],"cytoskeleton.":[164],"Moreover,":[165],"impairment":[167],"endocytosis":[169],"observed":[171],"synaptosomes":[173],"after":[174],"internalization":[175],"peptide":[179],"corresponding":[180],"site":[183],"interaction.":[185],"data":[187],"account":[188],"for":[189],"different":[191],"subcellular":[192],"distribution":[193],"specific":[201],"regulation":[202,219],"transduction":[205],"pathways":[206],"linked":[207],"activation":[210],"brain":[213],"implicate":[215],"membrane":[221],"trafficking":[222],"nerve":[224],"terminals.":[225]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2017,"cited_by_count":1},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":1},{"year":2012,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}