{"id":"https://openalex.org/W1484493435","doi":"https://doi.org/10.1128/jvi.27.3.490-504.1978","title":"Collaborative complementation study of temperature-sensitive mutants of herpes simplex virus types 1 and 2","display_name":"Collaborative complementation study of temperature-sensitive mutants of herpes simplex virus types 1 and 2","publication_year":1978,"publication_date":"1978-09-01","ids":{"openalex":"https://openalex.org/W1484493435","doi":"https://doi.org/10.1128/jvi.27.3.490-504.1978","mag":"1484493435","pmid":"https://pubmed.ncbi.nlm.nih.gov/212578","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/525836"},"language":"en","primary_location":{"id":"doi:10.1128/jvi.27.3.490-504.1978","doi":"https://doi.org/10.1128/jvi.27.3.490-504.1978","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jvi.27.3.490-504.1978","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["crossref","doaj","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://europepmc.org/pmc/articles/PMC525836","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5039113255","display_name":"Priscilla A. Schaffer","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P A Schaffer","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026181742","display_name":"V C Carter","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"V C Carter","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5113567126","display_name":"Morag C. Timbury","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M C Timbury","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":17.0179,"has_fulltext":false,"cited_by_count":130,"citation_normalized_percentile":{"value":0.99299152,"is_in_top_1_percent":true,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":95},"biblio":{"volume":"27","issue":"3","first_page":"490","last_page":"504"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10625","display_name":"Herpesvirus Infections and Treatments","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10625","display_name":"Herpesvirus Infections and Treatments","score":0.9984999895095825,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10981","display_name":"Cytomegalovirus and herpesvirus research","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11135","display_name":"Virology and Viral Diseases","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2713","display_name":"Epidemiology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/herpes-simplex-virus-type-1","display_name":"herpes simplex virus type 1","score":0.9779999852180481},{"id":"https://openalex.org/keywords/herpes-simplex-virus-type-2","display_name":"herpes simplex virus type 2","score":1.0},{"id":"https://openalex.org/keywords/temperature-sensitive-mutants","display_name":"temperature-sensitive mutants","score":0.9950000047683716},{"id":"https://openalex.org/keywords/complementation-groups","display_name":"complementation groups","score":0.843999981880188},{"id":"https://openalex.org/keywords/complementation-analysis","display_name":"complementation analysis","score":0.7839999794960022},{"id":"https://openalex.org/keywords/viral-gene-function","display_name":"viral gene function","score":0.44600000977516174}],"concepts":[{"id":"https://openalex.org/C188082640","wikidata":"https://www.wikidata.org/wiki/Q1780899","display_name":"Complementation","level":4,"score":0.9685713648796082},{"id":"https://openalex.org/C2781196997","wikidata":"https://www.wikidata.org/wiki/Q655331","display_name":"Herpes simplex virus","level":3,"score":0.8909481763839722},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.8475030660629272},{"id":"https://openalex.org/C143065580","wikidata":"https://www.wikidata.org/wiki/Q3285695","display_name":"Mutant","level":3,"score":0.7626289129257202},{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.7317802309989929},{"id":"https://openalex.org/C115867849","wikidata":"https://www.wikidata.org/wiki/Q753175","display_name":"Protein-fragment complementation assay","level":5,"score":0.5435859560966492},{"id":"https://openalex.org/C36372059","wikidata":"https://www.wikidata.org/wiki/Q376492","display_name":"HSL and HSV","level":3,"score":0.4919099807739258},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.447571337223053},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.23171812295913696},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.10650399327278137}],"mesh":[{"descriptor_ui":"D005814","descriptor_name":"Genes, Viral","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005816","descriptor_name":"Genetic Complementation Test","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":true},{"descriptor_ui":"D009154","descriptor_name":"Mutation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D013696","descriptor_name":"Temperature","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014779","descriptor_name":"Virus Replication","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018139","descriptor_name":"Simplexvirus","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":true},{"descriptor_ui":"D018139","descriptor_name":"Simplexvirus","qualifier_ui":"Q000254","qualifier_name":"growth & development","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1128/jvi.27.3.490-504.1978","doi":"https://doi.org/10.1128/jvi.27.3.490-504.1978","is_oa":false,"landing_page_url":"https://doi.org/10.1128/jvi.27.3.490-504.1978","pdf_url":null,"source":{"id":"https://openalex.org/S96615428","display_name":"Journal of Virology","issn_l":"0022-538X","issn":["0022-538X","1070-6321","1098-5514"],"is_oa":false,"is_in_doaj":true,"is_core":true,"listed_in":["anvur-scientific","cwts-core","doaj","dongbi-a","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320263","host_organization_name":"American Society for Microbiology","host_organization_lineage":["https://openalex.org/P4310320263"],"host_organization_lineage_names":["American Society for Microbiology"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of Virology","raw_type":"journal-article"},{"id":"pmh:oai:europepmc.org:243776","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC525836","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},{"id":"pmid:212578","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/212578","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal of virology","raw_type":"Comparative Study"},{"id":"pmh:oai:pubmedcentral.nih.gov:525836","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC525836/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"J Virol","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:243776","doi":null,"is_oa":true,"landing_page_url":"http://europepmc.org/pmc/articles/PMC525836","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"","raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.4000000059604645}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":33,"referenced_works":["https://openalex.org/W205782560","https://openalex.org/W1041168061","https://openalex.org/W1527418225","https://openalex.org/W1552766729","https://openalex.org/W1562226695","https://openalex.org/W1563094648","https://openalex.org/W1602265228","https://openalex.org/W1608801180","https://openalex.org/W1726413385","https://openalex.org/W1757069992","https://openalex.org/W1818519684","https://openalex.org/W1827992862","https://openalex.org/W1912151827","https://openalex.org/W1958981719","https://openalex.org/W1959686341","https://openalex.org/W1966823058","https://openalex.org/W1969579867","https://openalex.org/W1976112300","https://openalex.org/W1976494728","https://openalex.org/W1981835365","https://openalex.org/W1987045430","https://openalex.org/W1994730933","https://openalex.org/W2017289092","https://openalex.org/W2048150217","https://openalex.org/W2057595718","https://openalex.org/W2062556579","https://openalex.org/W2093475210","https://openalex.org/W2093510574","https://openalex.org/W2103724212","https://openalex.org/W2146829588","https://openalex.org/W2166399014","https://openalex.org/W2199779404","https://openalex.org/W2613645997"],"related_works":["https://openalex.org/W1562226695","https://openalex.org/W1998636126","https://openalex.org/W2166399014","https://openalex.org/W207327999","https://openalex.org/W7034423242","https://openalex.org/W1527418225","https://openalex.org/W1981564366","https://openalex.org/W2049772230","https://openalex.org/W1987045430","https://openalex.org/W2057144573"],"abstract_inverted_index":{"Twenty-three":[0],"complementation":[1,20],"groups":[2],"of":[3,12,28,34],"herpes":[4],"simplex":[5],"virus":[6],"type":[7],"1":[8],"(HSV-1)":[9],"and":[10,18,30],"20":[11],"HSV-2":[13,35],"were":[14],"identified":[15],"by":[16],"qualitative":[17],"quantitative":[19],"analysis":[21],"from":[22],"among":[23],"43":[24],"temperature-sensitive":[25],"(ts)":[26],"mutants":[27,33],"HSV-1":[29],"29":[31],"ts":[32],"which":[36],"had":[37],"been":[38],"isolated":[39],"independently":[40],"in":[41],"10":[42],"laboratories.":[43]},"counts_by_year":[{"year":2026,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":2}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}