{"id":"https://openalex.org/W1483659760","doi":"https://doi.org/10.1002/ijc.29632","title":"Clostridium perfringens enterotoxin C \u2010terminal domain labeled to fluorescent dyes for in vivo visualization of micrometastatic chemotherapy\u2010resistant ovarian cancer","display_name":"Clostridium perfringens enterotoxin C \u2010terminal domain labeled to fluorescent dyes for in vivo visualization of micrometastatic chemotherapy\u2010resistant ovarian cancer","publication_year":2015,"publication_date":"2015-06-11","ids":{"openalex":"https://openalex.org/W1483659760","doi":"https://doi.org/10.1002/ijc.29632","mag":"1483659760","pmid":"https://pubmed.ncbi.nlm.nih.gov/26060989","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/4573336"},"language":"en","primary_location":{"id":"doi:10.1002/ijc.29632","doi":"https://doi.org/10.1002/ijc.29632","is_oa":false,"landing_page_url":"https://doi.org/10.1002/ijc.29632","pdf_url":null,"source":{"id":"https://openalex.org/S5382288","display_name":"International Journal of Cancer","issn_l":"0020-7136","issn":["0020-7136","1097-0215"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Cancer","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4573336","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5041993659","display_name":"Emiliano Cocco","orcid":"https://orcid.org/0000-0002-1397-2656","observed_orcids":["https://orcid.org/0000-0002-1397-2656"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]},{"id":"https://openalex.org/I79940851","display_name":"University of Brescia","ror":"https://ror.org/02q2d2610","country_code":"IT","type":"education","lineage":["https://openalex.org/I79940851"]}],"countries":["IT","US"],"is_corresponding":false,"raw_author_name":"Emiliano Cocco","raw_affiliation_strings":["Department of Molecular and Translational Medicine, Palazzetto Polifunzionale, Brescia, Italy","Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Molecular and Translational Medicine, Palazzetto Polifunzionale, Brescia, Italy","institution_ids":["https://openalex.org/I79940851"]},{"raw_affiliation_string":"Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5049750913","display_name":"Erik M. Shapiro","orcid":"https://orcid.org/0000-0002-0901-5781","observed_orcids":["https://orcid.org/0000-0002-0901-5781"]},"institutions":[{"id":"https://openalex.org/I87216513","display_name":"Michigan State University","ror":"https://ror.org/05hs6h993","country_code":"US","type":"education","lineage":["https://openalex.org/I87216513"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Erik M. Shapiro","raw_affiliation_strings":["Department of Radiology, Michigan State University, East Lansing, MI"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Radiology, Michigan State University, East Lansing, MI","institution_ids":["https://openalex.org/I87216513"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5087338346","display_name":"Sara Gasparrini","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Sara Gasparrini","raw_affiliation_strings":["Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045925318","display_name":"Salvatore Lopez","orcid":"https://orcid.org/0000-0001-7705-3715","observed_orcids":["https://orcid.org/0000-0001-7705-3715"]},"institutions":[{"id":"https://openalex.org/I155125353","display_name":"Universit\u00e0 Campus Bio-Medico","ror":"https://ror.org/04gqx4x78","country_code":"IT","type":"education","lineage":["https://openalex.org/I155125353"]},{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["IT","US"],"is_corresponding":false,"raw_author_name":"Salvatore Lopez","raw_affiliation_strings":["Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT","Division of Gynecologic Oncology, University Campus Bio-Medico of Rome, Rome, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]},{"raw_affiliation_string":"Division of Gynecologic Oncology, University Campus Bio-Medico of Rome, Rome, Italy","institution_ids":["https://openalex.org/I155125353"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110450300","display_name":"Carlton L. Schwab","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Carlton L. Schwab","raw_affiliation_strings":["Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5046857977","display_name":"Stefania Bellone","orcid":"https://orcid.org/0000-0001-5909-5292","observed_orcids":["https://orcid.org/0000-0001-5909-5292"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Stefania Bellone","raw_affiliation_strings":["Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5075330842","display_name":"Ileana Bortolomai","orcid":"https://orcid.org/0000-0002-2592-1274","observed_orcids":["https://orcid.org/0000-0002-2592-1274"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ileana Bortolomai","raw_affiliation_strings":["Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110196551","display_name":"Nat\u00e1lia J. Sumi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Natalia J. Sumi","raw_affiliation_strings":["Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5027337412","display_name":"Elena Bonazzoli","orcid":"https://orcid.org/0000-0003-2024-8102","observed_orcids":["https://orcid.org/0000-0003-2024-8102"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elena Bonazzoli","raw_affiliation_strings":["Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5029807655","display_name":"Roberta Nicoletti","orcid":"https://orcid.org/0000-0001-6191-3856","observed_orcids":["https://orcid.org/0000-0001-6191-3856"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Roberta Nicoletti","raw_affiliation_strings":["Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5101419719","display_name":"Yang Deng","orcid":"https://orcid.org/0000-0001-9233-9500","observed_orcids":["https://orcid.org/0000-0001-9233-9500"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Yang Deng","raw_affiliation_strings":["Department of Biomedical Engineering, Yale University, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Yale University, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5012106344","display_name":"W. Mark Saltzman","orcid":"https://orcid.org/0000-0002-2163-549X","observed_orcids":["https://orcid.org/0000-0002-2163-549X"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"W. Mark Saltzman","raw_affiliation_strings":["Department of Biomedical Engineering, Yale University, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Biomedical Engineering, Yale University, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5024405586","display_name":"Caroline J. Zeiss","orcid":"https://orcid.org/0000-0003-1181-3544","observed_orcids":["https://orcid.org/0000-0003-1181-3544"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Caroline J. Zeiss","raw_affiliation_strings":["Department of Comparative Medicine, Yale School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Comparative Medicine, Yale School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5083529085","display_name":"Floriana Centritto","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Floriana Centritto","raw_affiliation_strings":["Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103653978","display_name":"Jonathan D. Black","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jonathan D. Black","raw_affiliation_strings":["Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5108433612","display_name":"Dan\u2010Arin Silasi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Dan\u2010Arin Silasi","raw_affiliation_strings":["Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5021257078","display_name":"Elena Ratner","orcid":"https://orcid.org/0000-0002-6277-6002","observed_orcids":["https://orcid.org/0000-0002-6277-6002"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Elena Ratner","raw_affiliation_strings":["Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5032849063","display_name":"Masoud Azodi","orcid":"https://orcid.org/0000-0002-0570-8089","observed_orcids":["https://orcid.org/0000-0002-0570-8089"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Masoud Azodi","raw_affiliation_strings":["Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5008166734","display_name":"Thomas Rutherford","orcid":"https://orcid.org/0000-0003-0087-8748","observed_orcids":["https://orcid.org/0000-0003-0087-8748"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Thomas J. Rutherford","raw_affiliation_strings":["Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026827320","display_name":"Peter E. Schwartz","orcid":"https://orcid.org/0000-0002-0845-3624","observed_orcids":["https://orcid.org/0000-0002-0845-3624"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Peter E. Schwartz","raw_affiliation_strings":["Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5103016982","display_name":"Sergio L. Pecorelli","orcid":"https://orcid.org/0000-0002-5126-4300","observed_orcids":["https://orcid.org/0000-0002-5126-4300"]},"institutions":[{"id":"https://openalex.org/I79940851","display_name":"University of Brescia","ror":"https://ror.org/02q2d2610","country_code":"IT","type":"education","lineage":["https://openalex.org/I79940851"]}],"countries":["IT"],"is_corresponding":false,"raw_author_name":"Sergio Pecorelli","raw_affiliation_strings":["Division of Gynecologic Oncology, University of Brescia, Brescia, Italy"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Gynecologic Oncology, University of Brescia, Brescia, Italy","institution_ids":["https://openalex.org/I79940851"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010339370","display_name":"Alessandro Davide Santin","orcid":"https://orcid.org/0000-0003-4724-9738","observed_orcids":["https://orcid.org/0000-0003-4724-9738"]},"institutions":[{"id":"https://openalex.org/I32971472","display_name":"Yale University","ror":"https://ror.org/03v76x132","country_code":"US","type":"education","lineage":["https://openalex.org/I32971472"]}],"countries":["US"],"is_corresponding":true,"raw_author_name":"Alessandro D. Santin","raw_affiliation_strings":["Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Obstetrics, Gynecology and Reproductive Sciences, Yale School of Medicine, New Haven, CT","institution_ids":["https://openalex.org/I32971472"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":["https://openalex.org/A5010339370"],"corresponding_institution_ids":["https://openalex.org/I32971472"],"apc_list":{"value":5030,"currency":"USD","value_usd":5030},"apc_paid":null,"fwci":5.3307,"has_fulltext":false,"cited_by_count":31,"citation_normalized_percentile":{"value":0.94891261,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"137","issue":"11","first_page":"2618","last_page":"2629"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10550","display_name":"Ovarian cancer diagnosis and treatment","score":0.6015999913215637,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10550","display_name":"Ovarian cancer diagnosis and treatment","score":0.6015999913215637,"subfield":{"id":"https://openalex.org/subfields/2743","display_name":"Reproductive Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12996","display_name":"Cancer Research and Treatments","score":0.1720000058412552,"subfield":{"id":"https://openalex.org/subfields/1305","display_name":"Biotechnology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10782","display_name":"Nanoplatforms for cancer theranostics","score":0.05719999969005585,"subfield":{"id":"https://openalex.org/subfields/2204","display_name":"Biomedical Engineering"},"field":{"id":"https://openalex.org/fields/22","display_name":"Engineering"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/clostridium-perfringens-enterotoxin","display_name":"Clostridium perfringens enterotoxin","score":0.9729999899864197},{"id":"https://openalex.org/keywords/c-terminal-binding-domain","display_name":"C-terminal binding domain","score":0.8330000042915344},{"id":"https://openalex.org/keywords/ovarian-cancer","display_name":"ovarian cancer","score":0.6940000057220459},{"id":"https://openalex.org/keywords/micrometastasis","display_name":"micrometastases","score":0.925000011920929},{"id":"https://openalex.org/keywords/in-vivo-fluorescence-imaging","display_name":"in vivo fluorescence imaging","score":0.6449999809265137},{"id":"https://openalex.org/keywords/claudin-3","display_name":"claudin-3","score":0.949999988079071},{"id":"https://openalex.org/keywords/claudin-4","display_name":"claudin-4","score":1.0},{"id":"https://openalex.org/keywords/chemoresistance","display_name":"chemoresistance","score":0.6520000100135803},{"id":"https://openalex.org/keywords/patient-derived-xenografts","display_name":"patient-derived xenografts","score":0.8870000243186951},{"id":"https://openalex.org/keywords/malignant-ascites","display_name":"malignant ascites","score":0.7760000228881836},{"id":"https://openalex.org/keywords/tumor-spheroids","display_name":"tumor spheroids","score":0.8399999737739563},{"id":"https://openalex.org/keywords/near-infrared-fluorescent-dyes","display_name":"near-infrared fluorescent dyes","score":0.5519999861717224},{"id":"https://openalex.org/keywords/peritoneal-metastasis-detection","display_name":"peritoneal metastasis detection","score":0.5960000157356262},{"id":"https://openalex.org/keywords/cytoreductive-surgery","display_name":"cytoreductive surgery","score":0.7730000019073486},{"id":"https://openalex.org/keywords/residual-disease-detection","display_name":"residual disease detection","score":0.6159999966621399}],"concepts":[{"id":"https://openalex.org/C2780427987","wikidata":"https://www.wikidata.org/wiki/Q172341","display_name":"Ovarian cancer","level":3,"score":0.7347526550292969},{"id":"https://openalex.org/C207001950","wikidata":"https://www.wikidata.org/wiki/Q141124","display_name":"In vivo","level":2,"score":0.6975882053375244},{"id":"https://openalex.org/C502942594","wikidata":"https://www.wikidata.org/wiki/Q3421914","display_name":"Cancer research","level":1,"score":0.5199381113052368},{"id":"https://openalex.org/C91881484","wikidata":"https://www.wikidata.org/wiki/Q191807","display_name":"Fluorescence","level":2,"score":0.468397855758667},{"id":"https://openalex.org/C66999527","wikidata":"https://www.wikidata.org/wiki/Q421978","display_name":"Enterotoxin","level":4,"score":0.4376300871372223},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.43384677171707153},{"id":"https://openalex.org/C2776694085","wikidata":"https://www.wikidata.org/wiki/Q974135","display_name":"Chemotherapy","level":2,"score":0.4145588278770447},{"id":"https://openalex.org/C121608353","wikidata":"https://www.wikidata.org/wiki/Q12078","display_name":"Cancer","level":2,"score":0.39319273829460144},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3811541199684143},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.3416646718978882},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.29569169878959656},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.13686051964759827},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.09693002700805664},{"id":"https://openalex.org/C121332964","wikidata":"https://www.wikidata.org/wiki/Q413","display_name":"Physics","level":0,"score":0.0},{"id":"https://openalex.org/C150903083","wikidata":"https://www.wikidata.org/wiki/Q7108","display_name":"Biotechnology","level":1,"score":0.0},{"id":"https://openalex.org/C547475151","wikidata":"https://www.wikidata.org/wiki/Q25419","display_name":"Escherichia coli","level":3,"score":0.0},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.0},{"id":"https://openalex.org/C62520636","wikidata":"https://www.wikidata.org/wiki/Q944","display_name":"Quantum mechanics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004768","descriptor_name":"Enterotoxins","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005456","descriptor_name":"Fluorescent Dyes","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010051","descriptor_name":"Ovarian Neoplasms","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D016513","descriptor_name":"Mice, SCID","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D023041","descriptor_name":"Xenograft Model Antitumor Assays","qualifier_ui":"Q000379","qualifier_name":"methods","is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D061206","descriptor_name":"Neoplasm Micrometastasis","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":true},{"descriptor_ui":"D062465","descriptor_name":"Claudin-3","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D062506","descriptor_name":"Claudin-4","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false}],"locations_count":4,"locations":[{"id":"doi:10.1002/ijc.29632","doi":"https://doi.org/10.1002/ijc.29632","is_oa":false,"landing_page_url":"https://doi.org/10.1002/ijc.29632","pdf_url":null,"source":{"id":"https://openalex.org/S5382288","display_name":"International Journal of Cancer","issn_l":"0020-7136","issn":["0020-7136","1097-0215"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International Journal of Cancer","raw_type":"journal-article"},{"id":"pmid:26060989","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/26060989","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"International journal of cancer","raw_type":"Journal Article"},{"id":"pmh:oai:europepmc.org:4048778","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4573336","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},{"id":"pmh:oai:pubmedcentral.nih.gov:4573336","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4573336","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":"Int J Cancer","raw_type":"Text"}],"best_oa_location":{"id":"pmh:oai:europepmc.org:4048778","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/4573336","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":0.9476000070571899,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[{"id":"https://openalex.org/G2085510428","display_name":null,"funder_award_id":"CA 16359","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G2894246699","display_name":null,"funder_award_id":"RF-2010-2313497","funder_id":"https://openalex.org/F4320321781","funder_display_name":"Ministero della Salute"},{"id":"https://openalex.org/G7413457524","display_name":"Integrated genomic analysis of racial disparities in endometrial cancer","funder_award_id":"U01CA176067","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G8586497223","display_name":"CPE Peptide-Based Nanoparticles for the Diagnosis and Therapy of Chemotherapy Res","funder_award_id":"R01CA154460","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"},{"id":"https://openalex.org/G9000916849","display_name":"Cancer Center Support Grant","funder_award_id":"P30CA016359","funder_id":"https://openalex.org/F4320337351","funder_display_name":"National Cancer Institute"}],"funders":[{"id":"https://openalex.org/F4320313344","display_name":"Discovery To Cure","ror":null},{"id":"https://openalex.org/F4320321781","display_name":"Ministero della Salute","ror":"https://ror.org/00789fa95"},{"id":"https://openalex.org/F4320332161","display_name":"National Institutes of Health","ror":"https://ror.org/01cwqze88"},{"id":"https://openalex.org/F4320337351","display_name":"National Cancer Institute","ror":"https://ror.org/040gcmg81"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":48,"referenced_works":["https://openalex.org/W1549719228","https://openalex.org/W1926941638","https://openalex.org/W1974452295","https://openalex.org/W1975857514","https://openalex.org/W1978467020","https://openalex.org/W1980760878","https://openalex.org/W1982723015","https://openalex.org/W1993215855","https://openalex.org/W1993728532","https://openalex.org/W2007918447","https://openalex.org/W2011486625","https://openalex.org/W2012139361","https://openalex.org/W2012964951","https://openalex.org/W2017751746","https://openalex.org/W2023519068","https://openalex.org/W2026762108","https://openalex.org/W2028946041","https://openalex.org/W2029108055","https://openalex.org/W2031210403","https://openalex.org/W2037222119","https://openalex.org/W2047739340","https://openalex.org/W2050817655","https://openalex.org/W2051980540","https://openalex.org/W2053777247","https://openalex.org/W2059931622","https://openalex.org/W2068854353","https://openalex.org/W2086105866","https://openalex.org/W2093408082","https://openalex.org/W2100265880","https://openalex.org/W2102280506","https://openalex.org/W2103997262","https://openalex.org/W2107204729","https://openalex.org/W2108664963","https://openalex.org/W2109793454","https://openalex.org/W2112579958","https://openalex.org/W2117954295","https://openalex.org/W2118012186","https://openalex.org/W2118952409","https://openalex.org/W2122191305","https://openalex.org/W2129234932","https://openalex.org/W2156631561","https://openalex.org/W2166933821","https://openalex.org/W2167722650","https://openalex.org/W2167829312","https://openalex.org/W2168544783","https://openalex.org/W2169961966","https://openalex.org/W2219978888","https://openalex.org/W2254624872"],"related_works":["https://openalex.org/W1985448148","https://openalex.org/W1560057429","https://openalex.org/W1982723015","https://openalex.org/W2063202596","https://openalex.org/W2581792764","https://openalex.org/W2126700451","https://openalex.org/W2412413417","https://openalex.org/W2030727139","https://openalex.org/W1985589802","https://openalex.org/W2732146598"],"abstract_inverted_index":{"Identification":[0],"of":[1,7,72,109,132,168,176,195,211,219,232,238],"micrometastatic":[2,170,220],"disease":[3,222,234],"at":[4,103,137,150,208,235],"the":[5,68,73,83,111,114,141,164,174,196,209,216,224,230,236],"time":[6,210,237],"surgery":[8,214,241],"remains":[9],"extremely":[10],"challenging":[11],"in":[12,21,34,123,153,165,181],"ovarian":[13,38,58,177,221],"cancer":[14,59],"patients.":[15],"We":[16,97],"used":[17],"fluorescence":[18,27,32,100,135,145],"microscopy,":[19],"an":[20],"vivo":[22,166],"imaging":[23],"system":[24],"and":[25,36,46,55,113,117,173,204,226],"a":[26,202],"stereo":[28],"microscope":[29],"to":[30,79,101,118],"evaluate":[31],"distribution":[33],"Claudin-3-":[35],"-4-overexpressing":[37],"tumors,":[39],"floating":[40,180],"tumor":[41,99,134,171,178],"clumps":[42],"isolated":[43],"from":[44],"ascites":[45,183],"healthy":[47,124],"organs.":[48],"To":[49],"do":[50],"so,":[51],"mice":[52],"harboring":[53],"chemotherapy-na\u00efve":[54],"chemotherapy-resistant":[56],"human":[57],"xenografts":[60,63],"or":[61,82,94,229],"patient-derived":[62],"(PDXs)":[64],"were":[65,185],"treated":[66],"with":[67],"carboxyl-terminal":[69],"binding":[70],"domain":[71],"Clostridium":[74],"perfringens":[75],"enterotoxin":[76],"(c-CPE)":[77],"conjugated":[78],"FITC":[80],"(FITC-c-CPE)":[81],"near-infrared":[84],"(NIR)":[85],"fluorescent":[86,158,197],"tag":[87],"IRDye":[88],"CW800":[89],"(CW800-c-CPE)":[90],"either":[91],"intraperitoneally":[92],"(IP)":[93],"intravenously":[95],"(IV).":[96],"found":[98,149],"plateau":[102],"30":[104],"min":[105],"after":[106,242],"IP":[107],"injection":[108,131],"both":[110,154],"FITC-c-CPE":[112],"CW800-c-CPE":[115],"peptides":[116],"be":[119],"significantly":[120],"higher":[121],"than":[122],"organs":[125],"(p":[126],"<":[127],"0.01).":[128],"After":[129],"IV":[130],"CW800-c-CPE,":[133],"plateaued":[136],"6":[138],"hr":[139,152],"while":[140],"most":[142],"favorable":[143],"tumor-to-background":[144],"ratio":[146],"(TBR)":[147],"was":[148,160],"48":[151],"mouse":[155],"models.":[156],"Importantly,":[157],"c-CPE":[159,198],"highly":[161],"sensitive":[162],"for":[163,215],"visualization":[167],"peritoneal":[169],"implants":[172],"identification":[175,231],"spheroids":[179],"malignant":[182],"that":[184],"otherwise":[186],"not":[187],"detectable":[188],"by":[189],"conventional":[190],"visual":[191],"observation.":[192],"The":[193],"use":[194],"peptide":[199],"may":[200],"represent":[201],"novel":[203],"effective":[205],"optical":[206],"approach":[207],"primary":[212],"debulking":[213,240],"real-time":[217],"detection":[218],"overexpressing":[223],"Claudin-3":[225],"-4":[227],"receptors":[228],"residual":[233],"interval":[239],"neoadjuvant":[243],"chemotherapy":[244],"treatment.":[245]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":2},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":1},{"year":2019,"cited_by_count":6},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":3},{"year":2016,"cited_by_count":8},{"year":2015,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}
