{"id":"https://openalex.org/W1482490816","doi":null,"title":"Susceptibility of Candida albicans to peroxidase-catalyzed oxidation products of thiocyanate, iodide and bromide.","display_name":"Susceptibility of Candida albicans to peroxidase-catalyzed oxidation products of thiocyanate, iodide and bromide.","publication_year":1992,"publication_date":"1992-12-01","ids":{"openalex":"https://openalex.org/W1482490816","mag":"1482490816","pmid":"https://pubmed.ncbi.nlm.nih.gov/1306188"},"language":"en","primary_location":{"id":"pmid:1306188","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1306188","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal de biologie buccale","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5024293443","display_name":"Patrick Majerus","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I132053463","display_name":"Universit\u00e9 Libre de Bruxelles","ror":"https://ror.org/01r9htc13","country_code":"BE","type":"education","lineage":["https://openalex.org/I132053463"]}],"countries":["BE"],"is_corresponding":false,"raw_author_name":"P M Majerus","raw_affiliation_strings":["Universit\u00e9 Libre de Bruxelles - Laboratoire Facultaire de Stomatologie, Belgium"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Universit\u00e9 Libre de Bruxelles - Laboratoire Facultaire de Stomatologie, Belgium","institution_ids":["https://openalex.org/I132053463"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5050781210","display_name":"Philippe Courtois","orcid":"https://orcid.org/0000-0002-1135-3157","observed_orcids":["https://orcid.org/0000-0002-1135-3157"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"P A Courtois","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3467,"has_fulltext":false,"cited_by_count":44,"citation_normalized_percentile":{"value":0.58939221,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":97},"biblio":{"volume":"20","issue":"4","first_page":"241","last_page":"5"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.7333999872207642,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10150","display_name":"Antifungal resistance and susceptibility","score":0.7333999872207642,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11597","display_name":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","score":0.030300000682473183,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12526","display_name":"Antimicrobial agents and applications","score":0.025800000876188278,"subfield":{"id":"https://openalex.org/subfields/2402","display_name":"Applied Microbiology and Biotechnology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/candida-albicans","display_name":"Candida albicans","score":1.0},{"id":"https://openalex.org/keywords/lactoperoxidase-system","display_name":"lactoperoxidase system","score":0.9139999747276306},{"id":"https://openalex.org/keywords/hypoiodite","display_name":"hypoiodite","score":0.7979999780654907},{"id":"https://openalex.org/keywords/thiocyanate","display_name":"thiocyanate","score":0.847000002861023},{"id":"https://openalex.org/keywords/iodide","display_name":"iodide","score":0.7720000147819519},{"id":"https://openalex.org/keywords/bromide","display_name":"bromide","score":0.9800000190734863},{"id":"https://openalex.org/keywords/peroxidase-catalyzed-oxidation","display_name":"peroxidase-catalyzed oxidation","score":0.871999979019165},{"id":"https://openalex.org/keywords/oral-candidiasis","display_name":"oral candidiasis","score":0.7210000157356262},{"id":"https://openalex.org/keywords/orthodontic-appliances","display_name":"orthodontic appliances","score":0.8529999852180481},{"id":"https://openalex.org/keywords/oral-candida","display_name":"oral candida","score":0.37299999594688416},{"id":"https://openalex.org/keywords/saliva","display_name":"saliva","score":0.3930000066757202},{"id":"https://openalex.org/keywords/antifungal-activity","display_name":"antifungal activity","score":0.652999997138977}],"concepts":[{"id":"https://openalex.org/C201956729","wikidata":"https://www.wikidata.org/wiki/Q412728","display_name":"Lactoperoxidase","level":4,"score":0.9322713017463684},{"id":"https://openalex.org/C2780917455","wikidata":"https://www.wikidata.org/wiki/Q310443","display_name":"Candida albicans","level":2,"score":0.8341268301010132},{"id":"https://openalex.org/C2776294642","wikidata":"https://www.wikidata.org/wiki/Q77747995","display_name":"Thiocyanate","level":2,"score":0.7164449691772461},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6313326358795166},{"id":"https://openalex.org/C2776300020","wikidata":"https://www.wikidata.org/wiki/Q422423","display_name":"Bromide","level":2,"score":0.623773992061615},{"id":"https://openalex.org/C2778870691","wikidata":"https://www.wikidata.org/wiki/Q44794658","display_name":"Iodide","level":2,"score":0.5912577509880066},{"id":"https://openalex.org/C89423630","wikidata":"https://www.wikidata.org/wiki/Q7193","display_name":"Microbiology","level":1,"score":0.5245097875595093},{"id":"https://openalex.org/C504460877","wikidata":"https://www.wikidata.org/wiki/Q155925","display_name":"Saliva","level":2,"score":0.5158395171165466},{"id":"https://openalex.org/C2778660310","wikidata":"https://www.wikidata.org/wiki/Q177998","display_name":"Agar","level":3,"score":0.4675053060054779},{"id":"https://openalex.org/C162008176","wikidata":"https://www.wikidata.org/wiki/Q419305","display_name":"Peroxidase","level":3,"score":0.3340425193309784},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.20348885655403137},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.19030633568763733},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.16856122016906738},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.13026165962219238},{"id":"https://openalex.org/C523546767","wikidata":"https://www.wikidata.org/wiki/Q10876","display_name":"Bacteria","level":2,"score":0.09309390187263489},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000143","descriptor_name":"Acids","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D001959","descriptor_name":"Bromates","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D001965","descriptor_name":"Bromides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D002176","descriptor_name":"Candida albicans","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006861","descriptor_name":"Hydrogen Peroxide","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D007454","descriptor_name":"Iodides","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D007455","descriptor_name":"Iodine","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D007784","descriptor_name":"Lactoperoxidase","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":false},{"descriptor_ui":"D010084","descriptor_name":"Oxidation-Reduction","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D010544","descriptor_name":"Peroxidases","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D012463","descriptor_name":"Saliva","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":false},{"descriptor_ui":"D012463","descriptor_name":"Saliva","qualifier_ui":"Q000737","qualifier_name":"chemistry","is_major_topic":false},{"descriptor_ui":"D012907","descriptor_name":"Smoking","qualifier_ui":"Q000503","qualifier_name":"physiopathology","is_major_topic":false},{"descriptor_ui":"D013861","descriptor_name":"Thiocyanates","qualifier_ui":"Q000494","qualifier_name":"pharmacology","is_major_topic":true},{"descriptor_ui":"D017613","descriptor_name":"Iodine Compounds","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"pmid:1306188","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1306188","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Journal de biologie buccale","raw_type":"Journal Article"},{"id":"pmh:oai:dipot.ulb.ac.be:2013/261055","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/2013/ULB-DIPOT:oai:dipot.ulb.ac.be:2013/261055","pdf_url":null,"source":{"id":"https://openalex.org/S4306401063","display_name":"D\u00e9p\u00f4t institutionnel de l'Universit\u00e9 libre de Bruxelles (Universit\u00e9 Libre de Bruxelles)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I132053463","host_organization_name":"Universit\u00e9 Libre de Bruxelles","host_organization_lineage":["https://openalex.org/I132053463"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Journal de biologie buccale, 20","raw_type":"info:eu-repo/semantics/article"},{"id":"mag:1482490816","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/1306188","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.4043000042438507,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W4256502347","https://openalex.org/W2013089488","https://openalex.org/W792406900","https://openalex.org/W1531672164","https://openalex.org/W50535422","https://openalex.org/W837480540","https://openalex.org/W1723147420","https://openalex.org/W1121089630","https://openalex.org/W2884455493","https://openalex.org/W235677281"],"abstract_inverted_index":{"The":[0,47],"susceptibility":[1],"of":[2,25,36,50,69,80,92,118,132],"Candida":[3,26,51,110],"albicans":[4,27,111],"(ATCC":[5],"10231":[6],"and":[7,41,84],"wild":[8],"strains)":[9],"to":[10,58,64,75,87,127],"hypo(pseudo)halous":[11],"ions":[12],"(OSCN-,":[13],"OBr-,":[14],"OI-)":[15],"produced":[16],"by":[17],"the":[18,34,67,78,90,116,119,130],"lactoperoxidase":[19,59],"system":[20,60,122],"was":[21,125],"tested.":[22],"Six":[23],"strains":[24],"were":[28],"isolated":[29],"from":[30,33,62,73,85],"swabs":[31],"taken":[32],"mouths":[35],"children":[37],"with":[38],"orthodontic":[39],"appliances":[40],"selected":[42],"on":[43,109],"Sabouraud-Chloramphenicol-Actidione":[44],"agar":[45],"plates.":[46],"survival":[48],"rate":[49],"blastospores":[52],"after":[53],"a":[54,103],"30":[55],"min":[56],"exposure":[57],"ranged":[61],"79":[63],"105%":[65],"in":[66,77,89,107,123],"presence":[68,79,91],"615":[70],"microM":[71,82,94],"thiocyanate,":[72],"56":[74],"88%":[76],"345":[81],"bromide":[83],"0":[86],"4%":[88],"250":[93],"iodide.":[95],"Results":[96],"showed":[97],"that":[98],"only":[99],"OI-":[100],"could":[101],"exert":[102],"strong":[104],"inhibiting":[105],"effect":[106],"vitro":[108],"at":[112],"physiological":[113],"concentrations.":[114],"Nevertheless,":[115],"activity":[117],"hypoiodite":[120],"generating":[121],"saliva":[124],"found":[126],"be":[128],"under":[129],"control":[131],"thiocyanate":[133],"concentration.":[134]},"counts_by_year":[{"year":2025,"cited_by_count":1},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":1},{"year":2021,"cited_by_count":2},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":2},{"year":2016,"cited_by_count":1},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2012,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}