{"id":"https://openalex.org/W1480788348","doi":null,"title":"Increased oncogenicity of the murine sarcoma virus (Moloney) by co-infection with murine leukemia viruses.","display_name":"Increased oncogenicity of the murine sarcoma virus (Moloney) by co-infection with murine leukemia viruses.","publication_year":1968,"publication_date":"1968-06-01","ids":{"openalex":"https://openalex.org/W1480788348","mag":"1480788348","pmid":"https://pubmed.ncbi.nlm.nih.gov/5658439"},"language":"en","primary_location":{"id":"pmid:5658439","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/5658439","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer research","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5109924216","display_name":"M. A. Chirigos","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M A Chirigos","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5045315266","display_name":"Kalman Perk","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"K Perk","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5111926518","display_name":"Willie Turner","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"W Turner","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5026512851","display_name":"B. L. Burka","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"B Burka","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5072789162","display_name":"Mar\u00eda de las Mercedes G\u00f3mez","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Gomez","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.8584,"has_fulltext":false,"cited_by_count":21,"citation_normalized_percentile":{"value":0.83607875,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"28","issue":"6","first_page":"1055","last_page":"63"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12159","display_name":"T-cell and Retrovirus Studies","score":0.9965999722480774,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10685","display_name":"Viral-associated cancers and disorders","score":0.00279999990016222,"subfield":{"id":"https://openalex.org/subfields/2730","display_name":"Oncology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T13385","display_name":"Infectious Diseases and Mycology","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2725","display_name":"Infectious Diseases"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/moloney-murine-sarcoma-virus","display_name":"Moloney murine sarcoma virus","score":0.9290000200271606},{"id":"https://openalex.org/keywords/rauscher-murine-leukemia-virus","display_name":"Rauscher leukemia virus","score":0.8309999704360962},{"id":"https://openalex.org/keywords/friend-leukemia-virus","display_name":"Friend leukemia virus","score":0.9649999737739563},{"id":"https://openalex.org/keywords/coinfection","display_name":"co-infection","score":0.7910000085830688},{"id":"https://openalex.org/keywords/oncogenicity","display_name":"oncogenicity","score":0.8510000109672546},{"id":"https://openalex.org/keywords/tumor-regression","display_name":"tumor regression","score":0.8799999952316284},{"id":"https://openalex.org/keywords/metastasis","display_name":"metastasis","score":0.8709999918937683},{"id":"https://openalex.org/keywords/helper-virus","display_name":"helper virus","score":0.7129999995231628},{"id":"https://openalex.org/keywords/immunosuppression","display_name":"immunosuppression","score":0.9900000095367432},{"id":"https://openalex.org/keywords/murine-leukemia-virus","display_name":"murine leukemia virus","score":0.7390000224113464},{"id":"https://openalex.org/keywords/sarcoma","display_name":"sarcoma","score":0.5870000123977661}],"concepts":[{"id":"https://openalex.org/C159047783","wikidata":"https://www.wikidata.org/wiki/Q7215","display_name":"Virology","level":1,"score":0.7049890756607056},{"id":"https://openalex.org/C2522874641","wikidata":"https://www.wikidata.org/wiki/Q808","display_name":"Virus","level":2,"score":0.6850596070289612},{"id":"https://openalex.org/C2778461978","wikidata":"https://www.wikidata.org/wiki/Q29496","display_name":"Leukemia","level":2,"score":0.6766852140426636},{"id":"https://openalex.org/C2778256501","wikidata":"https://www.wikidata.org/wiki/Q223911","display_name":"Sarcoma","level":2,"score":0.6756001114845276},{"id":"https://openalex.org/C2779562191","wikidata":"https://www.wikidata.org/wiki/Q673848","display_name":"Murine leukemia virus","level":3,"score":0.6441311240196228},{"id":"https://openalex.org/C2780635560","wikidata":"https://www.wikidata.org/wiki/Q1216998","display_name":"Neoplasm","level":2,"score":0.6155470013618469},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.6027034521102905},{"id":"https://openalex.org/C2780414542","wikidata":"https://www.wikidata.org/wiki/Q627992","display_name":"Rickettsia","level":3,"score":0.4154001474380493},{"id":"https://openalex.org/C180032290","wikidata":"https://www.wikidata.org/wiki/Q1664296","display_name":"Inoculation","level":2,"score":0.41209226846694946},{"id":"https://openalex.org/C142724271","wikidata":"https://www.wikidata.org/wiki/Q7208","display_name":"Pathology","level":1,"score":0.30662840604782104},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.2797147333621979},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.22301647067070007},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000917","descriptor_name":"Antibody Formation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005622","descriptor_name":"Friend murine leukemia virus","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":true},{"descriptor_ui":"D007273","descriptor_name":"Injections, Intramuscular","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007274","descriptor_name":"Injections, Intraperitoneal","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007279","descriptor_name":"Injections, Subcutaneous","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008979","descriptor_name":"Moloney murine leukemia virus","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":true},{"descriptor_ui":"D009365","descriptor_name":"Neoplasm Regression, Spontaneous","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D011925","descriptor_name":"Rauscher Virus","qualifier_ui":"Q000472","qualifier_name":"pathogenicity","is_major_topic":true},{"descriptor_ui":"D012513","descriptor_name":"Sarcoma, Experimental","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D012513","descriptor_name":"Sarcoma, Experimental","qualifier_ui":"Q000276","qualifier_name":"immunology","is_major_topic":false},{"descriptor_ui":"D012513","descriptor_name":"Sarcoma, Experimental","qualifier_ui":"Q000473","qualifier_name":"pathology","is_major_topic":false},{"descriptor_ui":"D014774","descriptor_name":"Virulence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"pmid:5658439","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/5658439","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Cancer research","raw_type":"Journal Article"},{"id":"mag:1480788348","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/5658439","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":20,"referenced_works":["https://openalex.org/W1512023473","https://openalex.org/W1541469138","https://openalex.org/W1547461742","https://openalex.org/W1550738411","https://openalex.org/W1574896010","https://openalex.org/W1594334572","https://openalex.org/W1595554659","https://openalex.org/W1999033249","https://openalex.org/W2017638565","https://openalex.org/W2024605339","https://openalex.org/W2032405381","https://openalex.org/W2067271037","https://openalex.org/W2079285600","https://openalex.org/W2099425538","https://openalex.org/W2106986883","https://openalex.org/W2122114629","https://openalex.org/W2143990736","https://openalex.org/W2162455476","https://openalex.org/W2408544175","https://openalex.org/W2415816874"],"related_works":["https://openalex.org/W2136756818","https://openalex.org/W1557318563","https://openalex.org/W1529218168","https://openalex.org/W7097021108","https://openalex.org/W2257571731","https://openalex.org/W2015121030","https://openalex.org/W72607960","https://openalex.org/W2116085998","https://openalex.org/W2129133543","https://openalex.org/W1926697983"],"abstract_inverted_index":{"The":[0,76],"high":[1],"incidence":[2],"of":[3,6,35,62,72,78],"spontaneous":[4],"regressions":[5],"primary":[7,63],"tumors":[8,42,65],"induced":[9],"by":[10,21,69],"the":[11,79],"Moloney":[12],"sarcoma":[13,36],"virus":[14],"in":[15,49,56],"adult":[16],"mice":[17],"was":[18],"significantly":[19],"altered":[20,68],"co-infection":[22],"with":[23],"Rauscher,":[24],"Moloney,":[25],"and":[26,59],"Friend":[27],"leukemia":[28,74,80],"viruses.":[29],"Intramuscular,":[30],"intraperitoneal,":[31],"or":[32,85],"subcutaneous":[33],"inoculation":[34],"extracts,":[37],"prepared":[38],"from":[39,44],"progressively":[40],"growing":[41],"obtained":[43],"dually":[45],"infected":[46],"animals,":[47],"resulted":[48],"extensive":[50],"metastases.":[51],"Tumor":[52],"nodules":[53],"were":[54],"observed":[55],"several":[57],"tissues":[58],"organs.":[60],"Regression":[61],"virus-induced":[64],"could":[66],"be":[67],"low":[70],"concentrations":[71],"Rauscher":[73],"virus.":[75],"role":[77],"virus,":[81],"acting":[82],"as":[83,86],"\u201chelper\u201d":[84],"an":[87],"immunosuppressor,":[88],"is":[89],"discussed.":[90]},"counts_by_year":[{"year":2020,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}