{"id":"https://openalex.org/W1478065430","doi":"https://doi.org/10.1016/s1054-3589(08)60011-3","title":"Prenatal and Neonatal Toxicology and Pathology of Heavy Metals","display_name":"Prenatal and Neonatal Toxicology and Pathology of Heavy Metals","publication_year":1980,"publication_date":"1980-01-01","ids":{"openalex":"https://openalex.org/W1478065430","doi":"https://doi.org/10.1016/s1054-3589(08)60011-3","mag":"1478065430","pmid":"https://pubmed.ncbi.nlm.nih.gov/7004140"},"language":"en","primary_location":{"id":"doi:10.1016/s1054-3589(08)60011-3","doi":"https://doi.org/10.1016/s1054-3589(08)60011-3","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s1054-3589(08)60011-3","pdf_url":null,"source":{"id":"https://openalex.org/S2764403048","display_name":"Advances in pharmacology","issn_l":"1054-3589","issn":["1054-3589","1557-8925"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Pharmacology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4246319066","display_name":null},"type":"book-chapter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5028190216","display_name":"Louis W. Chang","orcid":"https://orcid.org/0009-0004-3523-4808","observed_orcids":["https://orcid.org/0009-0004-3523-4808"]},"institutions":[{"id":"https://openalex.org/I79620101","display_name":"University of Arkansas for Medical Sciences","ror":"https://ror.org/00xcryt71","country_code":"US","type":"education","lineage":["https://openalex.org/I79620101"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Louis W. Chang","raw_affiliation_strings":["Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas","institution_ids":["https://openalex.org/I79620101"]}]},{"author_position":"middle","author":{"id":null,"display_name":"Paul R. Wade","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I79620101","display_name":"University of Arkansas for Medical Sciences","ror":"https://ror.org/00xcryt71","country_code":"US","type":"education","lineage":["https://openalex.org/I79620101"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Paul R. Wade","raw_affiliation_strings":["Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Pathology, University of Arkansas for Medical Sciences, Little Rock, Arkansas","institution_ids":["https://openalex.org/I79620101"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5038563335","display_name":"Joel G. Pounds","orcid":"https://orcid.org/0000-0002-6616-1566","observed_orcids":["https://orcid.org/0000-0002-6616-1566"]},"institutions":[{"id":"https://openalex.org/I1304557061","display_name":"National Center for Toxicological Research","ror":"https://ror.org/05jmhh281","country_code":"US","type":"facility","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1304557061","https://openalex.org/I1320320070"]},{"id":"https://openalex.org/I1320320070","display_name":"United States Food and Drug Administration","ror":"https://ror.org/034xvzb47","country_code":"US","type":"government","lineage":["https://openalex.org/I1299022934","https://openalex.org/I1320320070"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joel G. Pounds","raw_affiliation_strings":["Department of Health and Human Services, Food and Drug Administration, National Center for Toxicological Research, Jefferson, Arkansas"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Health and Human Services, Food and Drug Administration, National Center for Toxicological Research, Jefferson, Arkansas","institution_ids":["https://openalex.org/I1304557061","https://openalex.org/I1320320070"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5039403500","display_name":"Kenneth R. Reuhl","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210159778","display_name":"National Research Council Canada","ror":"https://ror.org/04mte1k06","country_code":"CA","type":"government","lineage":["https://openalex.org/I4210159778"]}],"countries":["CA"],"is_corresponding":false,"raw_author_name":"Kenneth R. Reuhl","raw_affiliation_strings":["Division of Biological Sciences, National Research Council of Canada Ottawa, Canada"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Biological Sciences, National Research Council of Canada Ottawa, Canada","institution_ids":["https://openalex.org/I4210159778"]}]}],"institutions":[],"countries_distinct_count":2,"institutions_distinct_count":4,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":5.9456,"has_fulltext":false,"cited_by_count":48,"citation_normalized_percentile":{"value":0.96326531,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":"17","issue":null,"first_page":"195","last_page":"231"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10790","display_name":"Heavy Metal Exposure and Toxicity","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},"topics":[{"id":"https://openalex.org/T10790","display_name":"Heavy Metal Exposure and Toxicity","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}},{"id":"https://openalex.org/T10915","display_name":"Trace Elements in Health","score":9.999999747378752e-05,"subfield":{"id":"https://openalex.org/subfields/2916","display_name":"Nutrition and Dietetics"},"field":{"id":"https://openalex.org/fields/29","display_name":"Nursing"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10819","display_name":"Mercury impact and mitigation studies","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2307","display_name":"Health, Toxicology and Mutagenesis"},"field":{"id":"https://openalex.org/fields/23","display_name":"Environmental Science"},"domain":{"id":"https://openalex.org/domains/3","display_name":"Physical Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/heavy-metal-toxicity","display_name":"heavy metal toxicity","score":0.8539999723434448},{"id":"https://openalex.org/keywords/prenatal-toxicity","display_name":"prenatal toxicity","score":0.7540000081062317},{"id":"https://openalex.org/keywords/neonatal-toxicity","display_name":"neonatal toxicity","score":0.9700000286102295},{"id":"https://openalex.org/keywords/fetal-toxicity","display_name":"fetal toxicity","score":0.8270000219345093},{"id":"https://openalex.org/keywords/teratogenicity","display_name":"teratogenicity","score":0.996999979019165},{"id":"https://openalex.org/keywords/mercury","display_name":"mercury","score":0.9679999947547913},{"id":"https://openalex.org/keywords/cadmium","display_name":"cadmium","score":1.0},{"id":"https://openalex.org/keywords/lead","display_name":"lead","score":1.0},{"id":"https://openalex.org/keywords/fetal-development","display_name":"fetal development","score":0.8640000224113464},{"id":"https://openalex.org/keywords/metal-metal-interactions","display_name":"metal-metal interaction","score":0.7689999938011169},{"id":"https://openalex.org/keywords/animal-to-human-extrapolation","display_name":"animal-to-human extrapolation","score":0.7369999885559082},{"id":"https://openalex.org/keywords/gestational-stage","display_name":"pregnancy stage","score":0.6499999761581421}],"concepts":[{"id":"https://openalex.org/C65290608","wikidata":"https://www.wikidata.org/wiki/Q631521","display_name":"Teratology","level":4,"score":0.6258358955383301},{"id":"https://openalex.org/C544657597","wikidata":"https://www.wikidata.org/wiki/Q1091","display_name":"Cadmium","level":2,"score":0.5770168900489807},{"id":"https://openalex.org/C2777777548","wikidata":"https://www.wikidata.org/wiki/Q206040","display_name":"Mercury (programming language)","level":2,"score":0.5448560118675232},{"id":"https://openalex.org/C2776053758","wikidata":"https://www.wikidata.org/wiki/Q105789","display_name":"Heavy metals","level":2,"score":0.5187604427337646},{"id":"https://openalex.org/C3018923374","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Prenatal exposure","level":4,"score":0.5133196711540222},{"id":"https://openalex.org/C33070731","wikidata":"https://www.wikidata.org/wiki/Q7218","display_name":"Toxicology","level":1,"score":0.4963851571083069},{"id":"https://openalex.org/C172680121","wikidata":"https://www.wikidata.org/wiki/Q26513","display_name":"Fetus","level":3,"score":0.4387560784816742},{"id":"https://openalex.org/C41157215","wikidata":"https://www.wikidata.org/wiki/Q3995923","display_name":"Environmental toxicology","level":3,"score":0.425006628036499},{"id":"https://openalex.org/C42407357","wikidata":"https://www.wikidata.org/wiki/Q521","display_name":"Physiology","level":1,"score":0.3392102122306824},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.33876511454582214},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.3313140869140625},{"id":"https://openalex.org/C107872376","wikidata":"https://www.wikidata.org/wiki/Q321355","display_name":"Environmental chemistry","level":1,"score":0.3094150424003601},{"id":"https://openalex.org/C2779234561","wikidata":"https://www.wikidata.org/wiki/Q11995","display_name":"Pregnancy","level":2,"score":0.3078276216983795},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.26666396856307983},{"id":"https://openalex.org/C29730261","wikidata":"https://www.wikidata.org/wiki/Q274160","display_name":"Toxicity","level":2,"score":0.2458210289478302},{"id":"https://openalex.org/C46973012","wikidata":"https://www.wikidata.org/wiki/Q28627","display_name":"Gestation","level":3,"score":0.16345834732055664},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.1023244559764862},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.09227347373962402},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.06658047437667847},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0},{"id":"https://openalex.org/C199360897","wikidata":"https://www.wikidata.org/wiki/Q9143","display_name":"Programming language","level":1,"score":0.0}],"mesh":[{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000831","descriptor_name":"Animals, Newborn","qualifier_ui":"Q000502","qualifier_name":"physiology","is_major_topic":true},{"descriptor_ui":"D001522","descriptor_name":"Behavior, Animal","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":false},{"descriptor_ui":"D002104","descriptor_name":"Cadmium","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D002104","descriptor_name":"Cadmium","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005333","descriptor_name":"Fetus","qualifier_ui":"Q000187","qualifier_name":"drug effects","is_major_topic":true},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007231","descriptor_name":"Infant, Newborn","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007854","descriptor_name":"Lead","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D007854","descriptor_name":"Lead","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D008628","descriptor_name":"Mercury","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":false},{"descriptor_ui":"D008670","descriptor_name":"Metals","qualifier_ui":"Q000633","qualifier_name":"toxicity","is_major_topic":true},{"descriptor_ui":"D011247","descriptor_name":"Pregnancy","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013723","descriptor_name":"Teratogens","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":2,"locations":[{"id":"doi:10.1016/s1054-3589(08)60011-3","doi":"https://doi.org/10.1016/s1054-3589(08)60011-3","is_oa":false,"landing_page_url":"https://doi.org/10.1016/s1054-3589(08)60011-3","pdf_url":null,"source":{"id":"https://openalex.org/S2764403048","display_name":"Advances in pharmacology","issn_l":"1054-3589","issn":["1054-3589","1557-8925"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["cwts-core","jufo-1","ki-jl-1","medline","norway-1"],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"book series"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Pharmacology","raw_type":"book-chapter"},{"id":"pmid:7004140","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/7004140","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in pharmacology and chemotherapy","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.8199999928474426,"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":184,"referenced_works":["https://openalex.org/W30332703","https://openalex.org/W51287221","https://openalex.org/W63419162","https://openalex.org/W84489622","https://openalex.org/W116436157","https://openalex.org/W124694473","https://openalex.org/W148200661","https://openalex.org/W170328162","https://openalex.org/W232163828","https://openalex.org/W242277415","https://openalex.org/W1509246128","https://openalex.org/W1538916116","https://openalex.org/W1550275794","https://openalex.org/W1566187056","https://openalex.org/W1607511638","https://openalex.org/W1648503383","https://openalex.org/W1649866496","https://openalex.org/W1749452014","https://openalex.org/W1761744046","https://openalex.org/W1764842337","https://openalex.org/W1965867559","https://openalex.org/W1967193527","https://openalex.org/W1967217355","https://openalex.org/W1967258299","https://openalex.org/W1969328312","https://openalex.org/W1969794872","https://openalex.org/W1970457261","https://openalex.org/W1973101262","https://openalex.org/W1973880274","https://openalex.org/W1975670252","https://openalex.org/W1975681137","https://openalex.org/W1978019554","https://openalex.org/W1978725417","https://openalex.org/W1979942205","https://openalex.org/W1980103745","https://openalex.org/W1981133351","https://openalex.org/W1982824291","https://openalex.org/W1984695051","https://openalex.org/W1985744310","https://openalex.org/W1986233053","https://openalex.org/W1987031223","https://openalex.org/W1987843387","https://openalex.org/W1989446088","https://openalex.org/W1989775655","https://openalex.org/W1990716727","https://openalex.org/W1992049367","https://openalex.org/W1994106213","https://openalex.org/W1994247568","https://openalex.org/W1995308822","https://openalex.org/W1995528890","https://openalex.org/W1997526440","https://openalex.org/W1997599298","https://openalex.org/W1998078640","https://openalex.org/W2003655092","https://openalex.org/W2005278487","https://openalex.org/W2005325434","https://openalex.org/W2006848554","https://openalex.org/W2007654283","https://openalex.org/W2008689215","https://openalex.org/W2014580749","https://openalex.org/W2015317486","https://openalex.org/W2017864511","https://openalex.org/W2019216880","https://openalex.org/W2019449265","https://openalex.org/W2019488951","https://openalex.org/W2019625609","https://openalex.org/W2019743214","https://openalex.org/W2022640886","https://openalex.org/W2022951331","https://openalex.org/W2022977525","https://openalex.org/W2023400558","https://openalex.org/W2023886934","https://openalex.org/W2024508848","https://openalex.org/W2026781499","https://openalex.org/W2027318006","https://openalex.org/W2027459319","https://openalex.org/W2029761254","https://openalex.org/W2030803389","https://openalex.org/W2030823419","https://openalex.org/W2032360504","https://openalex.org/W2033062233","https://openalex.org/W2034045346","https://openalex.org/W2034979126","https://openalex.org/W2035892254","https://openalex.org/W2036308176","https://openalex.org/W2036738633","https://openalex.org/W2037816833","https://openalex.org/W2040378243","https://openalex.org/W2040704723","https://openalex.org/W2040815282","https://openalex.org/W2041685263","https://openalex.org/W2044069875","https://openalex.org/W2044227734","https://openalex.org/W2046955346","https://openalex.org/W2047486655","https://openalex.org/W2047915193","https://openalex.org/W2048268631","https://openalex.org/W2048583863","https://openalex.org/W2049487025","https://openalex.org/W2049505012","https://openalex.org/W2049591510","https://openalex.org/W2050425562","https://openalex.org/W2052707854","https://openalex.org/W2053345625","https://openalex.org/W2055866039","https://openalex.org/W2056572740","https://openalex.org/W2057177124","https://openalex.org/W2057903726","https://openalex.org/W2057967367","https://openalex.org/W2059724763","https://openalex.org/W2060386913","https://openalex.org/W2063205842","https://openalex.org/W2063652293","https://openalex.org/W2063819772","https://openalex.org/W2064157415","https://openalex.org/W2065668646","https://openalex.org/W2065834971","https://openalex.org/W2066203733","https://openalex.org/W2066748330","https://openalex.org/W2068122949","https://openalex.org/W2068366947","https://openalex.org/W2068503638","https://openalex.org/W2069392736","https://openalex.org/W2071767806","https://openalex.org/W2073440343","https://openalex.org/W2074349607","https://openalex.org/W2075379709","https://openalex.org/W2077211623","https://openalex.org/W2081917596","https://openalex.org/W2085558466","https://openalex.org/W2089294208","https://openalex.org/W2092328127","https://openalex.org/W2092484381","https://openalex.org/W2092793862","https://openalex.org/W2093973340","https://openalex.org/W2094274377","https://openalex.org/W2094715026","https://openalex.org/W2094918617","https://openalex.org/W2097517784","https://openalex.org/W2097556831","https://openalex.org/W2100051831","https://openalex.org/W2101458682","https://openalex.org/W2115067964","https://openalex.org/W2116898630","https://openalex.org/W2119651157","https://openalex.org/W2121683239","https://openalex.org/W2123913813","https://openalex.org/W2127817071","https://openalex.org/W2127986423","https://openalex.org/W2139277812","https://openalex.org/W2142524521","https://openalex.org/W2142755527","https://openalex.org/W2147813788","https://openalex.org/W2147882440","https://openalex.org/W2162288856","https://openalex.org/W2165017018","https://openalex.org/W2166439728","https://openalex.org/W2169782831","https://openalex.org/W2211952258","https://openalex.org/W2226390603","https://openalex.org/W2273153213","https://openalex.org/W2279104464","https://openalex.org/W2315487530","https://openalex.org/W2320855862","https://openalex.org/W2321378101","https://openalex.org/W2321854006","https://openalex.org/W2325853831","https://openalex.org/W2329577487","https://openalex.org/W2329770198","https://openalex.org/W2333790887","https://openalex.org/W2336101128","https://openalex.org/W2342594101","https://openalex.org/W2409434165","https://openalex.org/W2411775371","https://openalex.org/W2415114006","https://openalex.org/W2416188906","https://openalex.org/W2419572814","https://openalex.org/W2624697376","https://openalex.org/W2887001719","https://openalex.org/W3010405063","https://openalex.org/W3044633628","https://openalex.org/W4206562851","https://openalex.org/W4230213196","https://openalex.org/W4293587391"],"related_works":["https://openalex.org/W152871635","https://openalex.org/W2411473379","https://openalex.org/W7043149085","https://openalex.org/W4385319588","https://openalex.org/W2117397291","https://openalex.org/W4200141104","https://openalex.org/W2048688370","https://openalex.org/W2883229740","https://openalex.org/W2050545674","https://openalex.org/W2144816080"],"abstract_inverted_index":null,"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2014,"cited_by_count":1},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}