{"id":"https://openalex.org/W147687554","doi":null,"title":"Clinical care of adult Turner syndrome--new aspects.","display_name":"Clinical care of adult Turner syndrome--new aspects.","publication_year":2012,"publication_date":"2012-05-01","ids":{"openalex":"https://openalex.org/W147687554","mag":"147687554","pmid":"https://pubmed.ncbi.nlm.nih.gov/22946288"},"language":"en","primary_location":{"id":"pmid:22946288","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22946288","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric endocrinology reviews : PER","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026693541","display_name":"Christian Trolle","orcid":"https://orcid.org/0000-0003-4556-9113","observed_orcids":["https://orcid.org/0000-0003-4556-9113"]},"institutions":[{"id":"https://openalex.org/I2802335433","display_name":"Aarhus University Hospital","ror":"https://ror.org/040r8fr65","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802335433"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Christian Trolle","raw_affiliation_strings":["Department of Endocrinology and Internal Medicine, Aarhus University Hospital, DK-8000 Aarhus C, Denmark"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Department of Endocrinology and Internal Medicine, Aarhus University Hospital, DK-8000 Aarhus C, Denmark","institution_ids":["https://openalex.org/I2802335433"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5066195458","display_name":"Kristian Havmand Mortensen","orcid":"https://orcid.org/0000-0002-8986-6067","observed_orcids":["https://orcid.org/0000-0002-8986-6067"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Kristian Havmand Mortensen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5061161904","display_name":"Britta Hjerrild","orcid":"https://orcid.org/0000-0002-1409-0516","observed_orcids":["https://orcid.org/0000-0002-1409-0516"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Britta E Hjerrild","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5086490370","display_name":"Line Hartvig Cleemann","orcid":"https://orcid.org/0000-0001-7734-5857","observed_orcids":["https://orcid.org/0000-0001-7734-5857"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Line Cleemann","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5054960294","display_name":"Claus H\u00f8jbjerg Gravholt","orcid":"https://orcid.org/0000-0001-5924-1720","observed_orcids":["https://orcid.org/0000-0001-5924-1720"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Claus H Gravholt","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":1.1739,"has_fulltext":false,"cited_by_count":20,"citation_normalized_percentile":{"value":0.76544792,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":97},"biblio":{"volume":"9 Suppl 2","issue":null,"first_page":"739","last_page":"49"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11077","display_name":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","score":0.9345999956130981,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T11077","display_name":"Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities","score":0.9345999956130981,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11956","display_name":"Sexual Differentiation and Disorders","score":0.03620000183582306,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T12823","display_name":"Adolescent and Pediatric Healthcare","score":0.018300000578165054,"subfield":{"id":"https://openalex.org/subfields/2735","display_name":"Pediatrics, Perinatology and Child Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/turner-syndrome","display_name":"Turner syndrome","score":0.9980000257492065},{"id":"https://openalex.org/keywords/adult-care","display_name":"adult care","score":0.8859999775886536},{"id":"https://openalex.org/keywords/sex-hormone-replacement-therapy","display_name":"sex hormone replacement therapy","score":0.7990000247955322},{"id":"https://openalex.org/keywords/puberty-induction","display_name":"puberty induction","score":0.8510000109672546},{"id":"https://openalex.org/keywords/aortic-dissection","display_name":"aortic dissection","score":0.8220000267028809},{"id":"https://openalex.org/keywords/cardiovascular-disease","display_name":"cardiovascular disease","score":0.9570000171661377},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.9789999723434448},{"id":"https://openalex.org/keywords/hypertension","display_name":"hypertension","score":0.7620000243186951},{"id":"https://openalex.org/keywords/osteoporosis","display_name":"osteoporosis","score":1.0},{"id":"https://openalex.org/keywords/hypothyroidism","display_name":"hypothyroidism","score":0.9409999847412109},{"id":"https://openalex.org/keywords/obesity","display_name":"obesity","score":0.8709999918937683},{"id":"https://openalex.org/keywords/growth-hormone-therapy","display_name":"growth hormone therapy","score":0.8460000157356262},{"id":"https://openalex.org/keywords/oxandrolone","display_name":"oxandrolone","score":0.9789999723434448},{"id":"https://openalex.org/keywords/transition-to-adult-care","display_name":"transition to adult care","score":0.7649999856948853},{"id":"https://openalex.org/keywords/multidisciplinary-care","display_name":"multidisciplinary care","score":0.878000020980835},{"id":"https://openalex.org/keywords/endocrine-disorders","display_name":"endocrine disorders","score":0.4869999885559082}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7185993790626526},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.6208178400993347},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.5556859970092773},{"id":"https://openalex.org/C2779683239","wikidata":"https://www.wikidata.org/wiki/Q202849","display_name":"Turner syndrome","level":2,"score":0.5426242351531982},{"id":"https://openalex.org/C187212893","wikidata":"https://www.wikidata.org/wiki/Q123028","display_name":"Pediatrics","level":1,"score":0.509028434753418},{"id":"https://openalex.org/C2777180221","wikidata":"https://www.wikidata.org/wiki/Q3025883","display_name":"Type 2 diabetes","level":3,"score":0.45714712142944336},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.42919525504112244},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.36822086572647095},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.2538660764694214},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.2447187602519989}],"mesh":[{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D002318","descriptor_name":"Cardiovascular Diseases","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D003920","descriptor_name":"Diabetes Mellitus","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008107","descriptor_name":"Liver Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D008107","descriptor_name":"Liver Diseases","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D010024","descriptor_name":"Osteoporosis","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D010024","descriptor_name":"Osteoporosis","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D013959","descriptor_name":"Thyroid Diseases","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D013959","descriptor_name":"Thyroid Diseases","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D014424","descriptor_name":"Turner Syndrome","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":true},{"descriptor_ui":"D014424","descriptor_name":"Turner Syndrome","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D016649","descriptor_name":"Primary Ovarian Insufficiency","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D016649","descriptor_name":"Primary Ovarian Insufficiency","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":false},{"descriptor_ui":"D060305","descriptor_name":"Transition to Adult Care","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true}],"locations_count":3,"locations":[{"id":"pmid:22946288","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22946288","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Pediatric endocrinology reviews : PER","raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:publications/f948c1ad-f8d3-4f18-939d-ef05cf81c0e5","doi":null,"is_oa":false,"landing_page_url":"https://pure.au.dk/portal/en/publications/f948c1ad-f8d3-4f18-939d-ef05cf81c0e5","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Trolle, C, Mortensen, K H, Hjerrild, B E, Cleemann, L H & Gravholt, C H 2012, 'Clinical care of adult Turner syndrome--new aspects', Pediatric Endocrinology Reviews, vol. 9 Suppl 2, pp. 739-49.","raw_type":"info:eu-repo/semantics/review"},{"id":"mag:147687554","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/22946288","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":89,"referenced_works":["https://openalex.org/W36487605","https://openalex.org/W1546212635","https://openalex.org/W1588917798","https://openalex.org/W1917209917","https://openalex.org/W1963941815","https://openalex.org/W1964360761","https://openalex.org/W1967551750","https://openalex.org/W1973648331","https://openalex.org/W1976544212","https://openalex.org/W1980043911","https://openalex.org/W1983539820","https://openalex.org/W1988504386","https://openalex.org/W1990858220","https://openalex.org/W1992965424","https://openalex.org/W1994973510","https://openalex.org/W1999569888","https://openalex.org/W2004805091","https://openalex.org/W2005859246","https://openalex.org/W2015479973","https://openalex.org/W2016362474","https://openalex.org/W2020025580","https://openalex.org/W2022349338","https://openalex.org/W2022948625","https://openalex.org/W2023067951","https://openalex.org/W2023931008","https://openalex.org/W2024866744","https://openalex.org/W2028306497","https://openalex.org/W2029105451","https://openalex.org/W2029653395","https://openalex.org/W2031255132","https://openalex.org/W2032912756","https://openalex.org/W2037733089","https://openalex.org/W2038913799","https://openalex.org/W2044446803","https://openalex.org/W2045123237","https://openalex.org/W2045253224","https://openalex.org/W2048818063","https://openalex.org/W2051963283","https://openalex.org/W2057378502","https://openalex.org/W2057862933","https://openalex.org/W2070324435","https://openalex.org/W2070564732","https://openalex.org/W2072016440","https://openalex.org/W2072679514","https://openalex.org/W2075443461","https://openalex.org/W2079591877","https://openalex.org/W2081983661","https://openalex.org/W2082405711","https://openalex.org/W2082690628","https://openalex.org/W2082901911","https://openalex.org/W2083931900","https://openalex.org/W2090621101","https://openalex.org/W2092513001","https://openalex.org/W2095486026","https://openalex.org/W2099082882","https://openalex.org/W2101988535","https://openalex.org/W2104963471","https://openalex.org/W2105153540","https://openalex.org/W2107988491","https://openalex.org/W2109534439","https://openalex.org/W2109605450","https://openalex.org/W2109669806","https://openalex.org/W2109706659","https://openalex.org/W2110292790","https://openalex.org/W2112322536","https://openalex.org/W2115279370","https://openalex.org/W2116129756","https://openalex.org/W2117364932","https://openalex.org/W2120147367","https://openalex.org/W2120922659","https://openalex.org/W2126606606","https://openalex.org/W2128005191","https://openalex.org/W2128831381","https://openalex.org/W2134441368","https://openalex.org/W2135591025","https://openalex.org/W2135755215","https://openalex.org/W2137201431","https://openalex.org/W2142558128","https://openalex.org/W2144783013","https://openalex.org/W2149926350","https://openalex.org/W2152860648","https://openalex.org/W2153857443","https://openalex.org/W2158801862","https://openalex.org/W2161581155","https://openalex.org/W2162829213","https://openalex.org/W2166383227","https://openalex.org/W2168216303","https://openalex.org/W2170664803","https://openalex.org/W3133615983"],"related_works":["https://openalex.org/W2120137153","https://openalex.org/W1977310611","https://openalex.org/W2130049764","https://openalex.org/W2794780280","https://openalex.org/W2082823863","https://openalex.org/W2124474702","https://openalex.org/W2782262128","https://openalex.org/W2090600711","https://openalex.org/W2085257614","https://openalex.org/W2115639395"],"abstract_inverted_index":{"Turner":[0],"syndrome":[1],"(TS)":[2],"is":[3,50,63,147,220,226,279,286],"characterized":[4],"by":[5,39],"numerous":[6],"medical":[7],"challenges":[8],"during":[9,30,153,261,305],"adolescence":[10],"and":[11,21,61,75,92,133,168,181,196,200,207,217,228,246,249,266,295],"adulthood.":[12,306],"Puberty":[13],"has":[14,104,139,243],"to":[15,67,125,129,281],"be":[16,55,130,230,264,272],"induced":[17],"in":[18,148,156,213,273],"most":[19,160,276],"cases,":[20],"female":[22,46,101],"sex":[23,102],"hormone":[24,180],"replacement":[25],"therapy":[26],"(HRT)":[27],"should":[28,54,263,271],"continue":[29],"adult":[31,126,154,239],"years.":[32],"These":[33],"issues":[34],"are":[35,163,169,187,209,252],"normally":[36],"dealt":[37],"with":[38,100,241,290],"the":[40,56,68,73,82,134,299],"paediatrician,":[41],"but":[42],"once":[43],"a":[44,201,231,256,267,287,291,302],"TS":[45,242,285],"enters":[47],"adulthood":[48,262],"it":[49],"less":[51],"clear":[52],"who":[53],"primary":[57],"care":[58,127,260,270],"giver.":[59],"Morbidity":[60],"mortality":[62],"increased,":[64],"especially":[65,131],"due":[66],"risk":[69,83],"of":[70,72,84,98,203,233,238,293,301],"dissection":[71],"aorta":[74],"other":[76,93,204],"cardiovascular":[77,234],"diseases,":[78],"as":[79,81,178],"well":[80,189],"type":[85,194],"2":[86],"diabetes,":[87,192],"hypertension,":[88],"osteoporosis,":[89],"thyroid":[90],"disease":[91],"diseases.":[94],"The":[95,120,236],"proper":[96,135,218],"dose":[97],"HRT":[99,114],"steroids":[103],"not":[105,116,140,171],"been":[106,117,142,244],"established,":[107],"and,":[108],"likewise,":[109],"benefits":[110],"and/or":[111],"drawbacks":[112],"from":[113,123],"have":[115],"thoroughly":[118],"evaluated.":[119],"transition":[121,138],"period":[122],"paediatric":[124],"seems":[128],"vulnerable":[132],"framework":[136,146,268],"for":[137,150,184,269],"yet":[141],"established.":[143],"Likewise,":[144],"no":[145],"place":[149],"continuous":[151],"follow-up":[152],"years":[155],"many":[157],"countries.":[158],"Today,":[159],"treatment":[161,183,219],"recommendations":[162],"based":[164],"on":[165],"expert":[166],"opinion":[167],"unfortunately":[170],"evidence":[172],"based,":[173],"although":[174],"more":[175,211],"areas,":[176],"such":[177],"growth":[179],"oxandrolone":[182],"increasing":[185],"height,":[186],"becoming":[188],"founded.":[190],"Osteoporosis,":[191],"both":[193],"1":[195],"2,":[197],"hypothyroidism,":[198],"obesity":[199],"host":[202],"endocrine":[205],"diseases":[206,294],"conditions":[208,296],"seen":[210],"frequently":[212],"TS.":[214],"Prevention,":[215],"intervention":[216],"only":[221],"just":[222],"being":[223,253],"recognized.":[224],"Hypertension":[225],"frequent":[227],"can":[229],"forerunner":[232],"disease.":[235],"description":[237],"life":[240],"broadened":[245],"medical,":[247],"social":[248],"psychological":[250],"aspects":[251],"added":[254],"at":[255],"compelling":[257],"pace.":[258],"Proper":[259],"studied":[265],"place,":[274],"since":[275],"morbidity":[277],"potentially":[278],"amenable":[280],"intervention.":[282],"In":[283],"summary,":[284],"condition":[288],"associated":[289],"number":[292],"which":[297],"need":[298],"attention":[300],"multi-disciplinary":[303],"team":[304]},"counts_by_year":[{"year":2024,"cited_by_count":2},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":1},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":1},{"year":2019,"cited_by_count":2},{"year":2016,"cited_by_count":2},{"year":2015,"cited_by_count":1},{"year":2014,"cited_by_count":3},{"year":2013,"cited_by_count":4}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}