{"id":"https://openalex.org/W146366320","doi":null,"title":"Aetiology, treatment and mortality after oesophageal perforation in Denmark.","display_name":"Aetiology, treatment and mortality after oesophageal perforation in Denmark.","publication_year":2011,"publication_date":"2011-05-01","ids":{"openalex":"https://openalex.org/W146366320","mag":"146366320","pmid":"https://pubmed.ncbi.nlm.nih.gov/21535984"},"language":"en","primary_location":{"id":"pmid:21535984","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21535984","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Danish medical bulletin","raw_type":"Journal Article"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5026253260","display_name":"Philip Ryom","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2802709434","display_name":"Rigshospitalet","ror":"https://ror.org/03mchdq19","country_code":"DK","type":"healthcare","lineage":["https://openalex.org/I2802567020","https://openalex.org/I2802709434","https://openalex.org/I4210145385"]}],"countries":["DK"],"is_corresponding":false,"raw_author_name":"Philip Ryom","raw_affiliation_strings":["Thoracic Surgery Department, Rigshospitalet, Blegdamsvej 9, Copenhagen, Denmark. philip.ryom@regionh.rh.dk"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Thoracic Surgery Department, Rigshospitalet, Blegdamsvej 9, Copenhagen, Denmark. philip.ryom@regionh.rh.dk","institution_ids":["https://openalex.org/I2802709434"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5062860495","display_name":"Jesper Bohsen Ravn","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Jesper Bohsen Ravn","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5047546792","display_name":"Luit Penninga","orcid":"https://orcid.org/0000-0002-8531-1865","observed_orcids":["https://orcid.org/0000-0002-8531-1865"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Luit Penninga","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":null,"display_name":"Susanne Schmidt","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Susanne Schmidt","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5110172083","display_name":"Maria Gerding Iversen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Maria Gerding Iversen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"middle","author":{"id":"https://openalex.org/A5069909682","display_name":"Peter Skov-Olsen","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Peter Skov-Olsen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]},{"author_position":"last","author":{"id":"https://openalex.org/A5025881972","display_name":"Henrik Kehlet","orcid":"https://orcid.org/0000-0002-2209-1711","observed_orcids":["https://orcid.org/0000-0002-2209-1711"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Henrik Kehlet","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":5.9523,"has_fulltext":false,"cited_by_count":66,"citation_normalized_percentile":{"value":0.9609589,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":99},"biblio":{"volume":"58","issue":"5","first_page":"A4267","last_page":"A4267"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11658","display_name":"Esophageal and GI Pathology","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11658","display_name":"Esophageal and GI Pathology","score":0.9990000128746033,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10619","display_name":"Esophageal Cancer Research and Treatment","score":0.0003000000142492354,"subfield":{"id":"https://openalex.org/subfields/2746","display_name":"Surgery"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11910","display_name":"Foreign Body Medical Cases","score":0.00019999999494757503,"subfield":{"id":"https://openalex.org/subfields/2733","display_name":"Otorhinolaryngology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/esophageal-perforation","display_name":"esophageal perforation","score":0.9990000128746033},{"id":"https://openalex.org/keywords/etiology","display_name":"etiology","score":0.8270000219345093},{"id":"https://openalex.org/keywords/iatrogenic-perforation","display_name":"iatrogenic perforation","score":0.9509999752044678},{"id":"https://openalex.org/keywords/endoscopic-instruments","display_name":"endoscopic instruments","score":0.6129999756813049},{"id":"https://openalex.org/keywords/boerhaave-syndrome","display_name":"Boerhaave syndrome","score":0.8820000290870667},{"id":"https://openalex.org/keywords/thoracotomy","display_name":"thoracotomy","score":0.7210000157356262},{"id":"https://openalex.org/keywords/debridement","display_name":"debridement","score":0.8650000095367432},{"id":"https://openalex.org/keywords/mortality","display_name":"mortality","score":0.5830000042915344},{"id":"https://openalex.org/keywords/conservative-treatment","display_name":"conservative treatment","score":0.7850000262260437},{"id":"https://openalex.org/keywords/length-of-hospital-stay","display_name":"length of hospital stay","score":0.6510000228881836},{"id":"https://openalex.org/keywords/rigid-endoscopy","display_name":"rigid endoscopy","score":0.7599999904632568},{"id":"https://openalex.org/keywords/treatment-guidelines","display_name":"treatment guidelines","score":0.628000020980835},{"id":"https://openalex.org/keywords/denmark","display_name":"Denmark","score":0.8379999995231628}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.9878910183906555},{"id":"https://openalex.org/C137627325","wikidata":"https://www.wikidata.org/wiki/Q156318","display_name":"Etiology","level":2,"score":0.7443009614944458},{"id":"https://openalex.org/C2778456384","wikidata":"https://www.wikidata.org/wiki/Q1508510","display_name":"Perforation","level":3,"score":0.5953852534294128},{"id":"https://openalex.org/C61434518","wikidata":"https://www.wikidata.org/wiki/Q932510","display_name":"General surgery","level":1,"score":0.4347727298736572},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4016014337539673},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.36530300974845886},{"id":"https://openalex.org/C191897082","wikidata":"https://www.wikidata.org/wiki/Q11467","display_name":"Metallurgy","level":1,"score":0.0},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.0},{"id":"https://openalex.org/C2778527123","wikidata":"https://www.wikidata.org/wiki/Q11750728","display_name":"Punching","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000293","descriptor_name":"Adolescent","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000328","descriptor_name":"Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000369","descriptor_name":"Aged, 80 and over","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002404","descriptor_name":"Catheterization","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D002648","descriptor_name":"Child","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002675","descriptor_name":"Child, Preschool","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003718","descriptor_name":"Denmark","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004106","descriptor_name":"Dilatation","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D004939","descriptor_name":"Esophageal Perforation","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":true},{"descriptor_ui":"D004939","descriptor_name":"Esophageal Perforation","qualifier_ui":"Q000401","qualifier_name":"mortality","is_major_topic":false},{"descriptor_ui":"D004939","descriptor_name":"Esophageal Perforation","qualifier_ui":"Q000628","qualifier_name":"therapy","is_major_topic":true},{"descriptor_ui":"D004945","descriptor_name":"Esophagoscopy","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D004945","descriptor_name":"Esophagoscopy","qualifier_ui":"Q000295","qualifier_name":"instrumentation","is_major_topic":false},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007223","descriptor_name":"Infant","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007441","descriptor_name":"Intubation, Gastrointestinal","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D007902","descriptor_name":"Length of Stay","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012189","descriptor_name":"Retrospective Studies","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012422","descriptor_name":"Rupture, Spontaneous","qualifier_ui":"Q000150","qualifier_name":"complications","is_major_topic":false},{"descriptor_ui":"D055815","descriptor_name":"Young Adult","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:21535984","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21535984","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Danish medical bulletin","raw_type":"Journal Article"},{"id":"pmh:oai:pure.atira.dk:openaire_cris_publications/bc4dbda0-f03a-4975-aa2f-cc92a5fddb8c","doi":null,"is_oa":false,"landing_page_url":"https://researchprofiles.ku.dk/da/publications/bc4dbda0-f03a-4975-aa2f-cc92a5fddb8c","pdf_url":null,"source":{"id":"https://openalex.org/S4306401983","display_name":"Research at the University of Copenhagen (University of Copenhagen)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I124055696","host_organization_name":"University of Copenhagen","host_organization_lineage":["https://openalex.org/I124055696"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Ryom, P, Ravn, J B, Penninga, L, Schmidt, S, Iversen, M G, Skov-Olsen, P & Kehlet, H 2011, 'Aetiology, treatment and mortality after oesophageal perforation in Denmark', Danish Medical Bulletin (Online), vol. 58, no. 5, pp. A4267.","raw_type":"info:eu-repo/semantics/article"},{"id":"mag:146366320","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/21535984","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"id":"https://metadata.un.org/sdg/3","score":1.0,"display_name":"Good health and well-being"}],"study_designs":[{"id":"https://openalex.org/study-designs/observational-study","display_name":"Observational Study"}],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":17,"referenced_works":["https://openalex.org/W1966049781","https://openalex.org/W1966513027","https://openalex.org/W1967983167","https://openalex.org/W1972419420","https://openalex.org/W1991253213","https://openalex.org/W1995428771","https://openalex.org/W2067313080","https://openalex.org/W2082313220","https://openalex.org/W2121307328","https://openalex.org/W2134732343","https://openalex.org/W2156340286","https://openalex.org/W2160437367","https://openalex.org/W2165527070","https://openalex.org/W2170863223","https://openalex.org/W2222522476","https://openalex.org/W2412979991","https://openalex.org/W2425715439"],"related_works":["https://openalex.org/W2083020154","https://openalex.org/W2053970570","https://openalex.org/W2141547703","https://openalex.org/W2025967801","https://openalex.org/W4297216541","https://openalex.org/W2418117280","https://openalex.org/W2418791286","https://openalex.org/W1966049781","https://openalex.org/W2060912367","https://openalex.org/W2981420804"],"abstract_inverted_index":{"INTRODUCTION:":[0],"Perforation":[1],"of":[2,32,37,64,71,88,94,114,124,139,204,213,237],"the":[3,6,30,35,57,72,95,115,125,165,196,199,205,211],"oesophagus":[4,73,96],"into":[5],"thoracic":[7,131],"cavity":[8],"is":[9,39,218,228],"a":[10,130,159,214],"potentially":[11],"life-threatening":[12],"condition.":[13],"The":[14,122,143,150],"causes":[15,31,89],"are":[16],"numerous.":[17],"Treatment":[18],"for":[19,134,235],"oesophageal":[20,238],"perforation":[21,33,70,157,239],"targets":[22],"mediastinal":[23],"and":[24,34,51,76,161,164,179,220,240],"pleural":[25],"contamination.":[26],"Present":[27],"knowledge":[28],"about":[29,137],"types":[36],"treatment":[38,119,174,236],"poor.":[40],"MATERIAL":[41],"AND":[42],"METHODS:":[43],"A":[44,62,85],"retrospective":[45],"review":[46],"was":[47,82,90,147,153],"made":[48],"between":[49],"1997":[50],"2005":[52],"based":[53],"on":[54],"extracts":[55],"from":[56],"National":[58],"Patient":[59],"Registry.":[60],"RESULTS:":[61],"total":[63],"286":[65],"patients":[66,116,126,140],"were":[67,127,191,208],"diagnosed":[68],"with":[69,175],"(131":[74],"women":[75],"155":[77],"men).":[78],"Their":[79],"average":[80,144],"age":[81],"60":[83],"years.":[84],"wide":[86],"spectrum":[87],"reported,":[91],"e.g.":[92],"instrumentation":[93],"136":[97],"(47.6%),":[98],"spontaneous":[99],"rupture":[100],"89":[101],"(31.1%)":[102],"or":[103],"procedures":[104],"otherwise":[105],"related":[106],"to":[107,129,230,241],"surgical":[108],"intervention":[109],"9":[110],"(3.1%).":[111],"One":[112],"third":[113],"started":[117],"conservative":[118],"91":[120],"(31.9%).":[121],"majority":[123],"transferred":[128],"surgery":[132],"department":[133],"further":[135],"treatment:":[136],"25%":[138],"underwent":[141],"surgery.":[142],"hospitalization":[145],"time":[146],"18":[148],"days.":[149],"mortality":[151],"rate":[152],"21%.":[154],"CONCLUSION:":[155],"Oesophageal":[156],"remains":[158],"diagnostic":[160],"therapeutic":[162],"challenge":[163],"condition":[166],"requires":[167],"aggressive":[168],"treatment.":[169,243],"Recent":[170],"consensus":[171],"in":[172,193],"early":[173],"thoracotomy,":[176],"debridement,":[177],"irrigation":[178],"subsequent":[180],"parenteral":[181],"nutrition":[182],"has":[183],"improved":[184],"survival.":[185],"In":[186,195],"this":[187],"material,":[188],"most":[189],"perforations":[190,207],"iatrogenic":[192,206],"nature.":[194],"2002-2005":[197],"period,":[198],"study":[200],"showed":[201],"that":[202],"29%":[203],"caused":[209],"by":[210],"use":[212,222],"rigid":[215],"endoscope":[216],"which":[217],"risky":[219],"whose":[221],"should":[223],"therefore":[224],"be":[225],"restricted.":[226],"It":[227],"advisable":[229],"set":[231],"up":[232],"national":[233],"guidelines":[234],"centralise":[242]},"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":2},{"year":2024,"cited_by_count":1},{"year":2023,"cited_by_count":4},{"year":2022,"cited_by_count":2},{"year":2021,"cited_by_count":9},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":3},{"year":2018,"cited_by_count":6},{"year":2017,"cited_by_count":4},{"year":2016,"cited_by_count":6},{"year":2015,"cited_by_count":5},{"year":2014,"cited_by_count":7},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":4}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}