{"id":"https://openalex.org/W145113570","doi":"https://doi.org/10.1016/b978-012098655-2/50043-0","title":"Estrogen","display_name":"Estrogen","publication_year":1999,"publication_date":"1999-01-01","ids":{"openalex":"https://openalex.org/W145113570","doi":"https://doi.org/10.1016/b978-012098655-2/50043-0","mag":"145113570"},"language":"en","primary_location":{"id":"doi:10.1016/b978-012098655-2/50043-0","doi":"https://doi.org/10.1016/b978-012098655-2/50043-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-012098655-2/50043-0","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Aging Skeleton","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4236026473","display_name":"The Aging Skeleton"},"type":"book-chapter","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5110093044","display_name":"Robert Lindsay","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I4210120848","display_name":"Helen Hayes Hospital","ror":"https://ror.org/02k4w3g59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210120848"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"ROBERT LINDSAY","raw_affiliation_strings":["Clinical Research Center, Helen Hayes Hospital, West Haverstraw, New York 10993"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Research Center, Helen Hayes Hospital, West Haverstraw, New York 10993","institution_ids":["https://openalex.org/I4210120848"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5028056767","display_name":"Felicia Cosman","orcid":"https://orcid.org/0000-0003-4554-6616","observed_orcids":["https://orcid.org/0000-0003-4554-6616"]},"institutions":[{"id":"https://openalex.org/I4210120848","display_name":"Helen Hayes Hospital","ror":"https://ror.org/02k4w3g59","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I4210120848"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"FELICIA COSMAN","raw_affiliation_strings":["Clinical Research Center, Helen Hayes Hospital, West Haverstraw, New York 10993"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Research Center, Helen Hayes Hospital, West Haverstraw, New York 10993","institution_ids":["https://openalex.org/I4210120848"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I4210120848"],"apc_list":null,"apc_paid":null,"fwci":1.1176,"has_fulltext":false,"cited_by_count":1,"citation_normalized_percentile":{"value":0.78113208,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":"495","last_page":"505"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.8881999850273132,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10071","display_name":"Bone health and osteoporosis research","score":0.8881999850273132,"subfield":{"id":"https://openalex.org/subfields/2732","display_name":"Orthopedics and Sports Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10694","display_name":"Menopause: Health Impacts and Treatments","score":0.06859999895095825,"subfield":{"id":"https://openalex.org/subfields/2712","display_name":"Endocrinology, Diabetes and Metabolism"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10756","display_name":"Estrogen and related hormone effects","score":0.025499999523162842,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/estrogen","display_name":"estrogen","score":0.9980000257492065},{"id":"https://openalex.org/keywords/bone-remodeling","display_name":"bone remodeling","score":0.800000011920929},{"id":"https://openalex.org/keywords/skeletal-homeostasis","display_name":"skeletal homeostasis","score":0.9200000166893005},{"id":"https://openalex.org/keywords/menopause","display_name":"menopause","score":0.7020000219345093},{"id":"https://openalex.org/keywords/postmenopausal-bone-loss","display_name":"postmenopausal bone loss","score":0.8730000257492065},{"id":"https://openalex.org/keywords/amenorrhea","display_name":"amenorrhea","score":0.7570000290870667},{"id":"https://openalex.org/keywords/gnrh-agonist","display_name":"GnRH agonist","score":0.8799999952316284},{"id":"https://openalex.org/keywords/endometriosis","display_name":"endometriosis","score":0.9639999866485596},{"id":"https://openalex.org/keywords/estrogen-replacement-therapy","display_name":"estrogen replacement therapy","score":0.7829999923706055},{"id":"https://openalex.org/keywords/combined-hormone-replacement-therapy","display_name":"combined hormone replacement therapy","score":0.9100000262260437},{"id":"https://openalex.org/keywords/trabecular-bone","display_name":"trabecular bone","score":0.8339999914169312},{"id":"https://openalex.org/keywords/bone-turnover","display_name":"bone turnover","score":0.7839999794960022},{"id":"https://openalex.org/keywords/bone-mass","display_name":"bone mass","score":0.578000009059906}],"concepts":[{"id":"https://openalex.org/C2777164284","wikidata":"https://www.wikidata.org/wiki/Q277954","display_name":"Estrogen","level":2,"score":0.8297387361526489},{"id":"https://openalex.org/C170033053","wikidata":"https://www.wikidata.org/wiki/Q952019","display_name":"Bone remodeling","level":2,"score":0.7809543609619141},{"id":"https://openalex.org/C2776350087","wikidata":"https://www.wikidata.org/wiki/Q265868","display_name":"Cancellous bone","level":2,"score":0.6917818784713745},{"id":"https://openalex.org/C2778562196","wikidata":"https://www.wikidata.org/wiki/Q177708","display_name":"Menopause","level":2,"score":0.6529445052146912},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.6363195776939392},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.6291611194610596},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.6156729459762573},{"id":"https://openalex.org/C2776541429","wikidata":"https://www.wikidata.org/wiki/Q165328","display_name":"Osteoporosis","level":2,"score":0.5490973591804504},{"id":"https://openalex.org/C18969341","wikidata":"https://www.wikidata.org/wiki/Q1169129","display_name":"Skeleton (computer programming)","level":2,"score":0.45708513259887695},{"id":"https://openalex.org/C2779329777","wikidata":"https://www.wikidata.org/wiki/Q2304401","display_name":"Bone density","level":3,"score":0.4529321789741516},{"id":"https://openalex.org/C2908647359","wikidata":"https://www.wikidata.org/wiki/Q2625603","display_name":"Population","level":2,"score":0.44032543897628784},{"id":"https://openalex.org/C2780159708","wikidata":"https://www.wikidata.org/wiki/Q17003363","display_name":"Hormone replacement therapy (female-to-male)","level":3,"score":0.4355437159538269},{"id":"https://openalex.org/C105702510","wikidata":"https://www.wikidata.org/wiki/Q514","display_name":"Anatomy","level":1,"score":0.0878855288028717},{"id":"https://openalex.org/C99454951","wikidata":"https://www.wikidata.org/wiki/Q932068","display_name":"Environmental health","level":1,"score":0.0},{"id":"https://openalex.org/C2779279991","wikidata":"https://www.wikidata.org/wiki/Q6058681","display_name":"Testosterone (patch)","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1016/b978-012098655-2/50043-0","doi":"https://doi.org/10.1016/b978-012098655-2/50043-0","is_oa":false,"landing_page_url":"https://doi.org/10.1016/b978-012098655-2/50043-0","pdf_url":null,"source":{"id":"https://openalex.org/S4306463230","display_name":"Elsevier eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310320990","host_organization_name":"Elsevier BV","host_organization_lineage":["https://openalex.org/P4310320990"],"host_organization_lineage_names":["Elsevier BV"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The Aging Skeleton","raw_type":"book-chapter"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9391000270843506}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":143,"referenced_works":["https://openalex.org/W30326195","https://openalex.org/W44375275","https://openalex.org/W95785129","https://openalex.org/W115779710","https://openalex.org/W187182211","https://openalex.org/W1561293749","https://openalex.org/W1910242855","https://openalex.org/W1922007189","https://openalex.org/W1928979506","https://openalex.org/W1964126860","https://openalex.org/W1964321896","https://openalex.org/W1966019630","https://openalex.org/W1967658281","https://openalex.org/W1968327793","https://openalex.org/W1968470315","https://openalex.org/W1970107478","https://openalex.org/W1970787765","https://openalex.org/W1976162459","https://openalex.org/W1979344569","https://openalex.org/W1985605692","https://openalex.org/W1987775806","https://openalex.org/W1987901471","https://openalex.org/W1990111600","https://openalex.org/W1992300708","https://openalex.org/W1996025707","https://openalex.org/W1996028579","https://openalex.org/W1996342523","https://openalex.org/W2000122738","https://openalex.org/W2001874782","https://openalex.org/W2002750604","https://openalex.org/W2002846661","https://openalex.org/W2002924549","https://openalex.org/W2004236425","https://openalex.org/W2005374613","https://openalex.org/W2011680382","https://openalex.org/W2011846252","https://openalex.org/W2014153785","https://openalex.org/W2015950286","https://openalex.org/W2016264860","https://openalex.org/W2019228090","https://openalex.org/W2019800555","https://openalex.org/W2021474004","https://openalex.org/W2022005523","https://openalex.org/W2023850671","https://openalex.org/W2025372252","https://openalex.org/W2028655493","https://openalex.org/W2029087187","https://openalex.org/W2031293802","https://openalex.org/W2031570803","https://openalex.org/W2032612949","https://openalex.org/W2033462832","https://openalex.org/W2035401846","https://openalex.org/W2035593552","https://openalex.org/W2037106265","https://openalex.org/W2037693711","https://openalex.org/W2038838869","https://openalex.org/W2041144723","https://openalex.org/W2043664160","https://openalex.org/W2047366838","https://openalex.org/W2050602528","https://openalex.org/W2051966996","https://openalex.org/W2052403955","https://openalex.org/W2052858021","https://openalex.org/W2053593143","https://openalex.org/W2053689432","https://openalex.org/W2056652223","https://openalex.org/W2058362889","https://openalex.org/W2061811154","https://openalex.org/W2063586368","https://openalex.org/W2063727524","https://openalex.org/W2064543888","https://openalex.org/W2066226218","https://openalex.org/W2066739013","https://openalex.org/W2066962971","https://openalex.org/W2067058076","https://openalex.org/W2067316892","https://openalex.org/W2067416918","https://openalex.org/W2067419903","https://openalex.org/W2070671126","https://openalex.org/W2072231974","https://openalex.org/W2072427778","https://openalex.org/W2072471551","https://openalex.org/W2072982824","https://openalex.org/W2073353512","https://openalex.org/W2073545276","https://openalex.org/W2074908862","https://openalex.org/W2077163152","https://openalex.org/W2078406992","https://openalex.org/W2078629144","https://openalex.org/W2078789031","https://openalex.org/W2080535189","https://openalex.org/W2082389883","https://openalex.org/W2084511654","https://openalex.org/W2088859172","https://openalex.org/W2092791248","https://openalex.org/W2094054100","https://openalex.org/W2112540452","https://openalex.org/W2113264115","https://openalex.org/W2113725512","https://openalex.org/W2116092458","https://openalex.org/W2117193676","https://openalex.org/W2118676056","https://openalex.org/W2125168145","https://openalex.org/W2127419261","https://openalex.org/W2143403216","https://openalex.org/W2145733834","https://openalex.org/W2148285186","https://openalex.org/W2151649765","https://openalex.org/W2155715664","https://openalex.org/W2157317148","https://openalex.org/W2158307830","https://openalex.org/W2237539561","https://openalex.org/W2269693708","https://openalex.org/W2285718597","https://openalex.org/W2290284735","https://openalex.org/W2304520185","https://openalex.org/W2315746182","https://openalex.org/W2320428286","https://openalex.org/W2321227665","https://openalex.org/W2331313671","https://openalex.org/W2332300541","https://openalex.org/W2339861034","https://openalex.org/W2340559658","https://openalex.org/W2341127235","https://openalex.org/W2406281434","https://openalex.org/W2408769131","https://openalex.org/W2409543769","https://openalex.org/W2409950688","https://openalex.org/W2410964925","https://openalex.org/W2419314833","https://openalex.org/W2616697655","https://openalex.org/W2742718982","https://openalex.org/W2970349349","https://openalex.org/W3012695018","https://openalex.org/W3025949784","https://openalex.org/W4236757670","https://openalex.org/W4245166850","https://openalex.org/W4246350214","https://openalex.org/W4252715326","https://openalex.org/W4296492010","https://openalex.org/W6601465373","https://openalex.org/W6619866131","https://openalex.org/W6697887508"],"related_works":["https://openalex.org/W1988859228","https://openalex.org/W2063620044","https://openalex.org/W30326195","https://openalex.org/W2048266085","https://openalex.org/W193814603","https://openalex.org/W8269608","https://openalex.org/W44326176","https://openalex.org/W2152453113","https://openalex.org/W4235392644","https://openalex.org/W2501129401"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}
