{"id":"https://openalex.org/W143597505","doi":"https://doi.org/10.1096/fasebj.23.1_supplement.628.22","title":"The Effects of IgG Anti D, IgG Anti D Coated Red Blood Cells and Lysed Red Blood Cells on Macrophage Viability, Morphology and Function","display_name":"The Effects of IgG Anti D, IgG Anti D Coated Red Blood Cells and Lysed Red Blood Cells on Macrophage Viability, Morphology and Function","publication_year":2009,"publication_date":"2009-04-01","ids":{"openalex":"https://openalex.org/W143597505","doi":"https://doi.org/10.1096/fasebj.23.1_supplement.628.22","mag":"143597505"},"language":"en","primary_location":{"id":"doi:10.1096/fasebj.23.1_supplement.628.22","doi":"https://doi.org/10.1096/fasebj.23.1_supplement.628.22","is_oa":false,"landing_page_url":"https://doi.org/10.1096/fasebj.23.1_supplement.628.22","pdf_url":null,"source":{"id":"https://openalex.org/S25293849","display_name":"The FASEB Journal","issn_l":"0892-6638","issn":["0892-6638","1530-6860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The FASEB Journal","raw_type":"journal-article"},"volume":null,"type":"article","indexed_in":["crossref"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":null,"display_name":"April Ellis","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800908891","display_name":"Hinds Community College","ror":"https://ror.org/008d28s71","country_code":"US","type":"education","lineage":["https://openalex.org/I2800908891"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"April Ellis","raw_affiliation_strings":["Biology Hinds Community College Jackson MS"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology Hinds Community College Jackson MS","institution_ids":["https://openalex.org/I2800908891"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5035422232","display_name":"Tyrah Hickman","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800908891","display_name":"Hinds Community College","ror":"https://ror.org/008d28s71","country_code":"US","type":"education","lineage":["https://openalex.org/I2800908891"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Tyrah Hickman","raw_affiliation_strings":["Biology Hinds Community College Jackson MS"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology Hinds Community College Jackson MS","institution_ids":["https://openalex.org/I2800908891"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5058711498","display_name":"JoAnna Hullitt","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I2800908891","display_name":"Hinds Community College","ror":"https://ror.org/008d28s71","country_code":"US","type":"education","lineage":["https://openalex.org/I2800908891"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"JoAnna Hullitt","raw_affiliation_strings":["Biology Hinds Community College Jackson MS"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology Hinds Community College Jackson MS","institution_ids":["https://openalex.org/I2800908891"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5011099358","display_name":"Michelle A. Tucci","orcid":"https://orcid.org/0000-0002-2380-9465","observed_orcids":["https://orcid.org/0000-0002-2380-9465"]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"Michelle Tucci","raw_affiliation_strings":["Orthopedics"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Orthopedics","institution_ids":[]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5057662159","display_name":"Ham A. Benghuzzi","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I29606459","display_name":"University of Mississippi Medical Center","ror":"https://ror.org/044pcn091","country_code":"US","type":"healthcare","lineage":["https://openalex.org/I29606459","https://openalex.org/I4210141039"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Ham Benghuzzi","raw_affiliation_strings":["Clinical Health Sciences University of Mississippi Medical Center Jackson MS"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Clinical Health Sciences University of Mississippi Medical Center Jackson MS","institution_ids":["https://openalex.org/I29606459"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5112187613","display_name":"Joseph A. Cameron","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I61937129","display_name":"Jackson State University","ror":"https://ror.org/01ecnnp60","country_code":"US","type":"education","lineage":["https://openalex.org/I4210141039","https://openalex.org/I61937129"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Joseph A. Cameron","raw_affiliation_strings":["Biology Jackson State University Jackson MS"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Biology Jackson State University Jackson MS","institution_ids":["https://openalex.org/I61937129"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":3,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":{"value":3740,"currency":"USD","value_usd":3740},"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":{"value":0.01594236,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":null,"biblio":{"volume":"23","issue":"S1","first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.37790000438690186,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10308","display_name":"Systemic Lupus Erythematosus Research","score":0.37790000438690186,"subfield":{"id":"https://openalex.org/subfields/2745","display_name":"Rheumatology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11597","display_name":"Neutrophil, Myeloperoxidase and Oxidative Mechanisms","score":0.19300000369548798,"subfield":{"id":"https://openalex.org/subfields/2403","display_name":"Immunology"},"field":{"id":"https://openalex.org/fields/24","display_name":"Immunology and Microbiology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11660","display_name":"Blood groups and transfusion","score":0.07500000298023224,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/macrophages","display_name":"macrophages","score":0.6869999766349792},{"id":"https://openalex.org/keywords/nitric-oxide","display_name":"nitric oxide","score":0.7089999914169312},{"id":"https://openalex.org/keywords/glutathione","display_name":"glutathione","score":0.9369999766349792},{"id":"https://openalex.org/keywords/malondialdehyde","display_name":"malondialdehyde","score":0.8199999928474426},{"id":"https://openalex.org/keywords/phagocytosis","display_name":"phagocytosis","score":0.8059999942779541},{"id":"https://openalex.org/keywords/macrophage-viability","display_name":"macrophage viability","score":0.6800000071525574},{"id":"https://openalex.org/keywords/macrophage-morphology","display_name":"macrophage morphology","score":0.8389999866485596},{"id":"https://openalex.org/keywords/organ-damage","display_name":"organ damage","score":0.5950000286102295},{"id":"https://openalex.org/keywords/igg-deposition","display_name":"IgG deposition","score":0.6650000214576721},{"id":"https://openalex.org/keywords/complement-mediated-injury","display_name":"complement-mediated injury","score":0.39500001072883606}],"concepts":[{"id":"https://openalex.org/C2779244956","wikidata":"https://www.wikidata.org/wiki/Q184204","display_name":"Macrophage","level":3,"score":0.6412907242774963},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.5829668641090393},{"id":"https://openalex.org/C57409179","wikidata":"https://www.wikidata.org/wiki/Q1218293","display_name":"Lysis","level":2,"score":0.5768092274665833},{"id":"https://openalex.org/C159654299","wikidata":"https://www.wikidata.org/wiki/Q79460","display_name":"Antibody","level":2,"score":0.499375581741333},{"id":"https://openalex.org/C203014093","wikidata":"https://www.wikidata.org/wiki/Q101929","display_name":"Immunology","level":1,"score":0.48506417870521545},{"id":"https://openalex.org/C160448771","wikidata":"https://www.wikidata.org/wiki/Q184726","display_name":"Phagocytosis","level":2,"score":0.4746340215206146},{"id":"https://openalex.org/C2776557347","wikidata":"https://www.wikidata.org/wiki/Q37187","display_name":"Red blood cell","level":2,"score":0.46625885367393494},{"id":"https://openalex.org/C538909803","wikidata":"https://www.wikidata.org/wiki/Q116907","display_name":"Glutathione","level":3,"score":0.4495141804218292},{"id":"https://openalex.org/C153911025","wikidata":"https://www.wikidata.org/wiki/Q7202","display_name":"Molecular biology","level":1,"score":0.44857749342918396},{"id":"https://openalex.org/C2780898057","wikidata":"https://www.wikidata.org/wiki/Q79448","display_name":"Immunoglobulin G","level":3,"score":0.44378355145454407},{"id":"https://openalex.org/C53227056","wikidata":"https://www.wikidata.org/wiki/Q189152","display_name":"Viability assay","level":3,"score":0.4273444414138794},{"id":"https://openalex.org/C16685009","wikidata":"https://www.wikidata.org/wiki/Q335057","display_name":"Andrology","level":1,"score":0.39958855509757996},{"id":"https://openalex.org/C1491633281","wikidata":"https://www.wikidata.org/wiki/Q7868","display_name":"Cell","level":2,"score":0.3304515779018402},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2495511770248413},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.19750189781188965},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.15652233362197876},{"id":"https://openalex.org/C202751555","wikidata":"https://www.wikidata.org/wiki/Q221681","display_name":"In vitro","level":2,"score":0.13933929800987244},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"doi:10.1096/fasebj.23.1_supplement.628.22","doi":"https://doi.org/10.1096/fasebj.23.1_supplement.628.22","is_oa":false,"landing_page_url":"https://doi.org/10.1096/fasebj.23.1_supplement.628.22","pdf_url":null,"source":{"id":"https://openalex.org/S25293849","display_name":"The FASEB Journal","issn_l":"0892-6638","issn":["0892-6638","1530-6860"],"is_oa":false,"is_in_doaj":false,"is_core":true,"listed_in":["anvur-scientific","cwts-core","dongbi-c","doyens","jufo-2","ki-jl-2","medline","norway-2","poland-140","russia-white-list-1","vabb-shw"],"host_organization":"https://openalex.org/P4310320595","host_organization_name":"Wiley","host_organization_lineage":["https://openalex.org/P4310320595"],"host_organization_lineage_names":["Wiley"],"type":"journal"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"The FASEB Journal","raw_type":"journal-article"}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","score":0.9537000060081482,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2140806529","https://openalex.org/W2428569237","https://openalex.org/W2128301775","https://openalex.org/W1966649467","https://openalex.org/W7058076603","https://openalex.org/W3025985549","https://openalex.org/W1817288858","https://openalex.org/W113144516","https://openalex.org/W1983064477","https://openalex.org/W1977552596"],"abstract_inverted_index":{"Immunoglobulin":[0],"G":[1],"(IgG)":[2],"deposition":[3,208],"at":[4],"tissue":[5],"sites":[6],"leads":[7],"to":[8,28,88,96,106,134,206],"macrophage":[9,49,200],"accumulation":[10],"and":[11,60,143,167,180],"organ":[12,203],"injury,":[13],"although":[14],"the":[15,30,71,78,81,97,100,113,125,128,150,153,165,189,207],"mechanism":[16],"for":[17,77,91,99,124,149],"injury":[18,204],"is":[19,175],"not":[20,161],"known.":[21],"The":[22],"goal":[23],"of":[24,32,80,127,152,191,199,209],"this":[25],"study":[26,129],"was":[27,122,137],"investigate":[29],"interaction":[31,190],"IgG":[33,37,107,140,144,194],"anti":[34,38,108,141,145],"D":[35,39,109,142,146],"alone,":[36],"coated":[40,110,147],"red":[41,73,157],"blood":[42,74,158],"cells":[43,50,159],"(RBCs),":[44],"or":[45],"lysed":[46,72,156],"RBCs":[47,111,148],"with":[48,193],"over":[51],"time.":[52],"Cell":[53,66],"viability,":[54],"cellular":[55,168],"glutathione":[56,84,115],"membrane":[57],"damage,":[58],"morphology,":[59],"nitric":[61],"oxide":[62],"(NO)":[63],"were":[64,68,86],"evaluated.":[65],"numbers":[67],"elevated":[69],"in":[70,130,139,202,212],"cell":[75],"treatment":[76],"duration":[79,126,151],"experiment.":[82],"Cellular":[83,120],"concentrations":[85],"similar":[87],"control":[89,98],"values":[90,116],"all":[92],"treated":[93,131],"groups":[94,132],"compared":[95,133],"first":[101],"48":[102],"hours.":[103,119],"Cells":[104],"exposed":[105],"showed":[112],"lowest":[114],"after":[117],"72":[118],"damage":[121],"evident":[123,138],"control.":[135],"NO":[136,174],"study,":[154],"whereas":[155],"did":[160],"increase":[162],"NO.":[163],"Overall,":[164],"biochemical":[166],"staining":[169],"results":[170],"possibly":[171],"indicate":[172],"that":[173],"a":[176],"receptor":[177],"mediated":[178],"event":[179],"phagocytosis":[181],"may":[182,195],"cause":[183],"increased":[184],"malondialdehyde":[185],"(MDA)":[186],"levels.":[187],"Evaluating":[188],"macrophages":[192],"advance":[196],"our":[197],"understanding":[198],"involvement":[201],"due":[205],"IgG.":[210],"Supported":[211],"part":[213],"by":[214],"NIGMS\u2010NIH":[215],"Grant":[216],"R25":[217],"GM50117.":[218]},"counts_by_year":[],"updated_date":"2026-09-29T14:09:16.559479","created_date":"2016-06-24T00:00:00"}