{"id":"https://openalex.org/W143543247","doi":null,"title":"Dynamic decision models for managing the major complications of diabetes","display_name":"Dynamic decision models for managing the major complications of diabetes","publication_year":2012,"publication_date":"2012-01-01","ids":{"openalex":"https://openalex.org/W143543247","mag":"143543247"},"language":"en","primary_location":{"id":"pmh:oai:d-scholarship.pitt.edu:16488","doi":null,"is_oa":false,"landing_page_url":"https://d-scholarship.pitt.edu/16488/1/Kurt_Murat_PhD.pdf","pdf_url":"https://d-scholarship.pitt.edu/16488/1/Kurt_Murat_PhD.pdf","source":{"id":"https://openalex.org/S4306402372","display_name":"D-Scholarship@Pitt (University of Pittsburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I170201317","host_organization_name":"University of Pittsburgh","host_organization_lineage":["https://openalex.org/I170201317"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"PeerReviewed"},"volume":null,"type":"article","is_traditional":true,"indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5101459706","display_name":"Murat Kurt","orcid":"https://orcid.org/0009-0008-9496-6215","observed_orcids":["https://orcid.org/0009-0008-9496-6215"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Murat Kurt","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5101459706"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.3119,"has_fulltext":false,"cited_by_count":4,"citation_normalized_percentile":{"value":0.6503281,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":96},"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T11163","display_name":"Organ Donation and Transplantation","score":0.29249998927116394,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T11163","display_name":"Organ Donation and Transplantation","score":0.29249998927116394,"subfield":{"id":"https://openalex.org/subfields/2739","display_name":"Public Health, Environmental and Occupational Health"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10804","display_name":"Health Systems, Economic Evaluations, Quality of Life","score":0.17239999771118164,"subfield":{"id":"https://openalex.org/subfields/2002","display_name":"Economics and Econometrics"},"field":{"id":"https://openalex.org/fields/20","display_name":"Economics, Econometrics and Finance"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}},{"id":"https://openalex.org/T11810","display_name":"Complex Systems and Decision Making","score":0.02879999950528145,"subfield":{"id":"https://openalex.org/subfields/1803","display_name":"Management Science and Operations Research"},"field":{"id":"https://openalex.org/fields/18","display_name":"Decision Sciences"},"domain":{"id":"https://openalex.org/domains/2","display_name":"Social Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/diabetes-complications","display_name":"diabetes complications","score":0.925000011920929},{"id":"https://openalex.org/keywords/paired-kidney-exchange","display_name":"paired kidney exchange","score":0.9129999876022339},{"id":"https://openalex.org/keywords/welfare-loss","display_name":"welfare loss","score":0.7160000205039978},{"id":"https://openalex.org/keywords/end-stage-renal-disease","display_name":"end-stage renal disease","score":0.8339999914169312},{"id":"https://openalex.org/keywords/type-2-diabetes","display_name":"type 2 diabetes","score":0.953000009059906},{"id":"https://openalex.org/keywords/statin-initiation","display_name":"statin initiation","score":0.9459999799728394},{"id":"https://openalex.org/keywords/lipid-ratios","display_name":"lipid ratios","score":0.671999990940094},{"id":"https://openalex.org/keywords/quality-adjusted-life-years","display_name":"quality-adjusted life years","score":0.8669999837875366},{"id":"https://openalex.org/keywords/markov-decision-process","display_name":"Markov decision process","score":0.8560000061988831},{"id":"https://openalex.org/keywords/control-limit-policy","display_name":"control limit policy","score":0.9039999842643738}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.585999608039856},{"id":"https://openalex.org/C2911091166","wikidata":"https://www.wikidata.org/wiki/Q106419912","display_name":"Transplantation","level":2,"score":0.5840505957603455},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.5454850196838379},{"id":"https://openalex.org/C2779978075","wikidata":"https://www.wikidata.org/wiki/Q202301","display_name":"Dialysis","level":2,"score":0.5371232032775879},{"id":"https://openalex.org/C555293320","wikidata":"https://www.wikidata.org/wiki/Q12206","display_name":"Diabetes mellitus","level":2,"score":0.5228050947189331},{"id":"https://openalex.org/C2780303639","wikidata":"https://www.wikidata.org/wiki/Q740909","display_name":"Kidney transplantation","level":3,"score":0.4670623242855072},{"id":"https://openalex.org/C2779134260","wikidata":"https://www.wikidata.org/wiki/Q12136","display_name":"Disease","level":2,"score":0.4616907835006714},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.24304696917533875},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.13493266701698303},{"id":"https://openalex.org/C134018914","wikidata":"https://www.wikidata.org/wiki/Q162606","display_name":"Endocrinology","level":1,"score":0.0}],"mesh":[],"locations_count":2,"locations":[{"id":"pmh:oai:d-scholarship.pitt.edu:16488","doi":null,"is_oa":false,"landing_page_url":"https://d-scholarship.pitt.edu/16488/1/Kurt_Murat_PhD.pdf","pdf_url":"https://d-scholarship.pitt.edu/16488/1/Kurt_Murat_PhD.pdf","source":{"id":"https://openalex.org/S4306402372","display_name":"D-Scholarship@Pitt (University of Pittsburgh)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I170201317","host_organization_name":"University of Pittsburgh","host_organization_lineage":["https://openalex.org/I170201317"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"acceptedVersion","is_accepted":true,"is_published":false,"raw_source_name":null,"raw_type":"PeerReviewed"},{"id":"mag:143543247","doi":null,"is_oa":false,"landing_page_url":"http://d-scholarship.pitt.edu/16488/1/Kurt_Murat_PhD.pdf","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.9537000060081482}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":202,"referenced_works":["https://openalex.org/W35214883","https://openalex.org/W76204639","https://openalex.org/W147249049","https://openalex.org/W165595137","https://openalex.org/W185379059","https://openalex.org/W984792769","https://openalex.org/W1480317510","https://openalex.org/W1481965470","https://openalex.org/W1496590343","https://openalex.org/W1497145588","https://openalex.org/W1497947438","https://openalex.org/W1502524639","https://openalex.org/W1521135953","https://openalex.org/W1538880854","https://openalex.org/W1539799297","https://openalex.org/W1545314021","https://openalex.org/W1553259710","https://openalex.org/W1554560005","https://openalex.org/W1561959875","https://openalex.org/W1569631138","https://openalex.org/W1595046345","https://openalex.org/W1603412719","https://openalex.org/W1608527539","https://openalex.org/W1644821451","https://openalex.org/W1893499607","https://openalex.org/W1907356258","https://openalex.org/W1947690049","https://openalex.org/W1960351623","https://openalex.org/W1963623923","https://openalex.org/W1966351368","https://openalex.org/W1966512701","https://openalex.org/W1971030732","https://openalex.org/W1971574914","https://openalex.org/W1976575214","https://openalex.org/W1976743028","https://openalex.org/W1977030023","https://openalex.org/W1977584003","https://openalex.org/W1977686415","https://openalex.org/W1977792628","https://openalex.org/W1979373091","https://openalex.org/W1979755048","https://openalex.org/W1982289187","https://openalex.org/W1982718314","https://openalex.org/W1984702972","https://openalex.org/W1984831729","https://openalex.org/W1985072250","https://openalex.org/W1987974958","https://openalex.org/W1990038658","https://openalex.org/W1991565409","https://openalex.org/W1991774389","https://openalex.org/W1993522535","https://openalex.org/W1994420481","https://openalex.org/W1995219873","https://openalex.org/W1998364070","https://openalex.org/W1998478117","https://openalex.org/W1998524277","https://openalex.org/W1998948639","https://openalex.org/W2007042905","https://openalex.org/W2009426114","https://openalex.org/W2010518325","https://openalex.org/W2012238036","https://openalex.org/W2013768719","https://openalex.org/W2014423093","https://openalex.org/W2014511571","https://openalex.org/W2014759828","https://openalex.org/W2015899437","https://openalex.org/W2017030375","https://openalex.org/W2019836894","https://openalex.org/W2020747826","https://openalex.org/W2022944070","https://openalex.org/W2026399893","https://openalex.org/W2029005850","https://openalex.org/W2031968478","https://openalex.org/W2033434075","https://openalex.org/W2036336974","https://openalex.org/W2037988320","https://openalex.org/W2039104542","https://openalex.org/W2041074255","https://openalex.org/W2042796309","https://openalex.org/W2044575357","https://openalex.org/W2045516356","https://openalex.org/W2047474181","https://openalex.org/W2049060968","https://openalex.org/W2049172358","https://openalex.org/W2051896332","https://openalex.org/W2052039838","https://openalex.org/W2052776501","https://openalex.org/W2054689128","https://openalex.org/W2057212234","https://openalex.org/W2058235270","https://openalex.org/W2059078444","https://openalex.org/W2059158127","https://openalex.org/W2059219149","https://openalex.org/W2065864121","https://openalex.org/W2066654039","https://openalex.org/W2066827333","https://openalex.org/W2067236087","https://openalex.org/W2067454783","https://openalex.org/W2068115726","https://openalex.org/W2068708142","https://openalex.org/W2068908293","https://openalex.org/W2069830071","https://openalex.org/W2070499881","https://openalex.org/W2071173534","https://openalex.org/W2071797343","https://openalex.org/W2074675717","https://openalex.org/W2075583794","https://openalex.org/W2075667278","https://openalex.org/W2076234854","https://openalex.org/W2077343443","https://openalex.org/W2079934540","https://openalex.org/W2081083774","https://openalex.org/W2083680012","https://openalex.org/W2088997895","https://openalex.org/W2089277992","https://openalex.org/W2089558414","https://openalex.org/W2089675743","https://openalex.org/W2091630536","https://openalex.org/W2091966857","https://openalex.org/W2094365507","https://openalex.org/W2096701473","https://openalex.org/W2098936448","https://openalex.org/W2099117927","https://openalex.org/W2099775880","https://openalex.org/W2101732436","https://openalex.org/W2102069181","https://openalex.org/W2103616816","https://openalex.org/W2104026547","https://openalex.org/W2105362864","https://openalex.org/W2107217702","https://openalex.org/W2107295258","https://openalex.org/W2107430902","https://openalex.org/W2108479359","https://openalex.org/W2108701118","https://openalex.org/W2110620341","https://openalex.org/W2111007919","https://openalex.org/W2112972371","https://openalex.org/W2113442255","https://openalex.org/W2114465684","https://openalex.org/W2117191092","https://openalex.org/W2117408463","https://openalex.org/W2117650506","https://openalex.org/W2119567691","https://openalex.org/W2123048773","https://openalex.org/W2125164113","https://openalex.org/W2125477986","https://openalex.org/W2126477578","https://openalex.org/W2126927428","https://openalex.org/W2127246271","https://openalex.org/W2127670733","https://openalex.org/W2129750583","https://openalex.org/W2130873593","https://openalex.org/W2131499798","https://openalex.org/W2131723452","https://openalex.org/W2132292375","https://openalex.org/W2133418261","https://openalex.org/W2134270369","https://openalex.org/W2134350845","https://openalex.org/W2136080736","https://openalex.org/W2138420606","https://openalex.org/W2141295779","https://openalex.org/W2141953826","https://openalex.org/W2142149543","https://openalex.org/W2142523037","https://openalex.org/W2145632027","https://openalex.org/W2146114745","https://openalex.org/W2147487746","https://openalex.org/W2149132564","https://openalex.org/W2149969907","https://openalex.org/W2151256554","https://openalex.org/W2152622190","https://openalex.org/W2152907289","https://openalex.org/W2153568425","https://openalex.org/W2156858670","https://openalex.org/W2157373537","https://openalex.org/W2161756000","https://openalex.org/W2162662969","https://openalex.org/W2163059046","https://openalex.org/W2163109667","https://openalex.org/W2165924268","https://openalex.org/W2166943421","https://openalex.org/W2214291492","https://openalex.org/W2234443685","https://openalex.org/W2331898814","https://openalex.org/W2337109902","https://openalex.org/W2337454357","https://openalex.org/W2338830734","https://openalex.org/W2344071092","https://openalex.org/W2403167642","https://openalex.org/W2405234559","https://openalex.org/W2415936577","https://openalex.org/W2504275771","https://openalex.org/W2575731723","https://openalex.org/W2734952077","https://openalex.org/W2764353567","https://openalex.org/W2790161616","https://openalex.org/W2990108307","https://openalex.org/W3121213783","https://openalex.org/W3124032376","https://openalex.org/W3124757962","https://openalex.org/W4232414536","https://openalex.org/W4239570539"],"related_works":["https://openalex.org/W1561433320","https://openalex.org/W3081543935","https://openalex.org/W3144419844","https://openalex.org/W2363462959","https://openalex.org/W2901562120","https://openalex.org/W7056970668","https://openalex.org/W1975746978","https://openalex.org/W2166436958","https://openalex.org/W7221154605","https://openalex.org/W2612117485"],"abstract_inverted_index":{"Diabetes":[0],"is":[1,50,65],"the":[2,17,24,51,70,116,186,197,201,250,273,281,292,315,321,334,339],"sixth-leading":[3],"cause":[4,10],"of":[5,11,27,74,81,165,199,203,216,252,294,323,333],"death":[6],"and":[7,13,29,46,72,131,146,157,194,219,221,304,306,319],"a":[8,66,79,97,129,138,154,159,170,266],"major":[9,25],"cardiovascular":[12],"renal":[14,54,59],"diseases":[15],"in":[16,40,90,128,336,338],"U.S.":[18,340],"In":[19,96],"this":[20],"dissertation,":[21],"we":[22],"consider":[23,119,249],"complications":[26],"diabetes":[28,212],"develop":[30],"dynamic":[31],"decision":[32,268],"models":[33],"for":[34,57,76,149,258,291],"two":[35,120],"important":[36],"timing":[37,135],"problems:":[38],"Transplantation":[39,49],"prearranged":[41],"paired":[42],"kidney":[43],"exchanges":[44],"(PKEs)":[45],"statin":[47,256],"initiation.":[48],"most":[52],"viable":[53],"replacement":[55],"therapy":[56,257],"end-stage":[58],"disease":[60],"(ESRD)":[61],"patients,":[62],"but":[63,240],"there":[64],"severe":[67],"disparity":[68],"between":[69,83],"demand":[71],"supply":[73],"kidneys":[75,82],"transplantation.":[77],"PKE,":[78,99,130],"cross-exchange":[80],"incompatible":[84,94],"patient-donor":[85],"pairs,":[86],"overcomes":[87],"many":[88],"difficulties":[89],"matching":[91],"patients":[92,122,259],"with":[93,123,209,260,297],"donors.":[95],"typical":[98],"transplantation":[100],"surgeries":[101],"take":[102],"place":[103],"simultaneously":[104],"so":[105],"that":[106,196],"no":[107],"donor":[108],"may":[109,205,243],"renege":[110],"after":[111],"her":[112],"intended":[113],"recipient":[114],"receives":[115],"kidney.":[117],"We":[118,143,175,184,248,264,287,313],"autonomous":[121],"probabilistically":[124],"evolving":[125],"health":[126],"statuses":[127],"model":[132,178,309],"their":[133,241,329],"transplant":[134],"decisions":[136,151],"as":[137],"discrete-time":[139],"non-zero-sum":[140],"stochastic":[141],"game.":[142],"explore":[144],"necessary":[145],"sufficient":[147,289],"conditions":[148,290],"patients'":[150],"to":[152,168,191,236,245,254,271,280,299,331],"form":[153],"stationary-perfect":[155,173],"equilibrium,":[156],"formulate":[158,265],"mixed-integer":[160],"linear":[161],"programming":[162],"(MIP)":[163],"representation":[164],"equilibrium":[166],"constraints":[167],"characterize":[169],"socially":[171],"optimal":[172,316],"equilibrium.":[174],"calibrate":[176],"our":[177,308],"using":[179,310],"large":[180],"scale":[181],"clinical":[182,311],"data.":[183,312],"quantify":[185],"social":[187],"welfare":[188],"loss":[189],"due":[190],"patient":[192],"autonomy":[193],"demonstrate":[195],"objective":[198],"maximizing":[200],"number":[202],"transplants":[204],"be":[206,234],"undesirable.":[207],"Patients":[208],"Type":[210,261],"2":[211,262],"have":[213],"higher":[214],"risk":[215],"heart":[217,283],"attack":[218,284],"stroke,":[220],"if":[222],"not":[223],"treated":[224],"these":[225],"risks":[226],"are":[227],"confounded":[228],"by":[229,327],"lipid":[230],"abnormalities.":[231],"Statins":[232],"can":[233],"used":[235],"treat":[237],"such":[238],"abnormalities,":[239],"use":[242,337],"lead":[244],"adverse":[246],"outcomes.":[247],"question":[251],"when":[253],"initiate":[255],"diabetes.":[263],"Markov":[267],"process":[269],"(MDP)":[270],"maximize":[272],"patient's":[274,300],"quality-adjusted":[275],"life":[276],"years":[277],"(QALYs)":[278],"prior":[279],"first":[282],"or":[285],"stroke.":[286],"derive":[288],"optimality":[293],"control-limit":[295],"policies":[296,318],"respect":[298],"lipid-ratio":[301],"(LR)":[302],"levels":[303],"age":[305],"parameterize":[307],"compute":[314],"treatment":[317,325],"illustrate":[320],"importance":[322],"individualized":[324],"factors":[326],"comparing":[328],"performance":[330],"those":[332],"guidelines":[335]},"counts_by_year":[{"year":2019,"cited_by_count":1},{"year":2018,"cited_by_count":2},{"year":2015,"cited_by_count":1}],"updated_date":"2026-11-06T12:05:46.655746","created_date":"2016-06-24T00:00:00"}