{"id":"https://openalex.org/W143208934","doi":null,"title":"Identification and Functional Analysis of Alternatively Spliced Isoforms of Soluble Adenylyl Cyclase in Human Bronchial Epithelial Cells","display_name":"Identification and Functional Analysis of Alternatively Spliced Isoforms of Soluble Adenylyl Cyclase in Human Bronchial Epithelial Cells","publication_year":2014,"publication_date":"2014-12-15","ids":{"openalex":"https://openalex.org/W143208934","mag":"143208934"},"language":"en","primary_location":{"id":"mag:143208934","doi":null,"is_oa":false,"landing_page_url":"https://scholarlyrepository.miami.edu/oa_dissertations/1344/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null},"volume":null,"type":"dissertation","indexed_in":[],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5100329932","display_name":"Xi Chen","orcid":"https://orcid.org/0000-0002-3160-614X","observed_orcids":["https://orcid.org/0000-0002-3160-614X"]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Xi Chen","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5100329932"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9672999978065491,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T10604","display_name":"RNA Research and Splicing","score":0.9672999978065491,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12434","display_name":"Phosphodiesterase function and regulation","score":0.005799999926239252,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11178","display_name":"Receptor Mechanisms and Signaling","score":0.00570000009611249,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/soluble-adenylyl-cyclase","display_name":"soluble adenylyl cyclase","score":0.9950000047683716},{"id":"https://openalex.org/keywords/alternative-splicing","display_name":"alternative splicing","score":0.9120000004768372},{"id":"https://openalex.org/keywords/protein-isoforms","display_name":"protein isoforms","score":0.8220000267028809},{"id":"https://openalex.org/keywords/human-bronchial-epithelial-cells","display_name":"human bronchial epithelial cells","score":0.9020000100135803},{"id":"https://openalex.org/keywords/camp-signaling","display_name":"cAMP signaling","score":0.6899999976158142},{"id":"https://openalex.org/keywords/gene-expression-regulation","display_name":"gene expression regulation","score":0.3959999978542328}],"concepts":[{"id":"https://openalex.org/C2779178603","wikidata":"https://www.wikidata.org/wiki/Q356257","display_name":"Adenylyl cyclase","level":3,"score":0.6803918480873108},{"id":"https://openalex.org/C53345823","wikidata":"https://www.wikidata.org/wiki/Q5531554","display_name":"Gene isoform","level":3,"score":0.6759375929832458},{"id":"https://openalex.org/C116834253","wikidata":"https://www.wikidata.org/wiki/Q2039217","display_name":"Identification (biology)","level":2,"score":0.5119901299476624},{"id":"https://openalex.org/C69101867","wikidata":"https://www.wikidata.org/wiki/Q17709777","display_name":"ADCY9","level":4,"score":0.5038911700248718},{"id":"https://openalex.org/C95444343","wikidata":"https://www.wikidata.org/wiki/Q7141","display_name":"Cell biology","level":1,"score":0.47087275981903076},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.4600294828414917},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.3737351894378662},{"id":"https://openalex.org/C70721500","wikidata":"https://www.wikidata.org/wiki/Q177005","display_name":"Computational biology","level":1,"score":0.36523115634918213},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.3395065665245056},{"id":"https://openalex.org/C181199279","wikidata":"https://www.wikidata.org/wiki/Q8047","display_name":"Enzyme","level":2,"score":0.21313443779945374},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.20813164114952087},{"id":"https://openalex.org/C59822182","wikidata":"https://www.wikidata.org/wiki/Q441","display_name":"Botany","level":1,"score":0.0}],"mesh":[],"locations_count":1,"locations":[{"id":"mag:143208934","doi":null,"is_oa":false,"landing_page_url":"https://scholarlyrepository.miami.edu/oa_dissertations/1344/","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"score":0.5683000087738037,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"pdf":false,"grobid_xml":false},"content_urls":null,"referenced_works_count":75,"referenced_works":["https://openalex.org/W14555943","https://openalex.org/W1538622176","https://openalex.org/W1543222911","https://openalex.org/W1601129141","https://openalex.org/W1696199194","https://openalex.org/W1933463815","https://openalex.org/W1959400241","https://openalex.org/W1963999476","https://openalex.org/W1964323668","https://openalex.org/W1968956612","https://openalex.org/W1970061319","https://openalex.org/W1971377917","https://openalex.org/W1972067938","https://openalex.org/W1984265769","https://openalex.org/W1995059934","https://openalex.org/W1995495646","https://openalex.org/W1999992114","https://openalex.org/W2003066928","https://openalex.org/W2004739727","https://openalex.org/W2005647411","https://openalex.org/W2007770546","https://openalex.org/W2008727454","https://openalex.org/W2016617586","https://openalex.org/W2018013006","https://openalex.org/W2018048045","https://openalex.org/W2020702016","https://openalex.org/W2021164331","https://openalex.org/W2023243075","https://openalex.org/W2029943684","https://openalex.org/W2032979918","https://openalex.org/W2033758177","https://openalex.org/W2035222385","https://openalex.org/W2037239929","https://openalex.org/W2038120522","https://openalex.org/W2045131720","https://openalex.org/W2045232151","https://openalex.org/W2047659985","https://openalex.org/W2054380003","https://openalex.org/W2055211442","https://openalex.org/W2055622424","https://openalex.org/W2057108552","https://openalex.org/W2059056983","https://openalex.org/W2061471552","https://openalex.org/W2065252129","https://openalex.org/W2071512322","https://openalex.org/W2071613443","https://openalex.org/W2082390426","https://openalex.org/W2087735334","https://openalex.org/W2090170422","https://openalex.org/W2094969755","https://openalex.org/W2095869636","https://openalex.org/W2097849839","https://openalex.org/W2100682779","https://openalex.org/W2101123370","https://openalex.org/W2101451982","https://openalex.org/W2105750530","https://openalex.org/W2111090400","https://openalex.org/W2113283367","https://openalex.org/W2118537438","https://openalex.org/W2119986079","https://openalex.org/W2120041114","https://openalex.org/W2131970968","https://openalex.org/W2134415267","https://openalex.org/W2144001627","https://openalex.org/W2144827439","https://openalex.org/W2148393113","https://openalex.org/W2152579394","https://openalex.org/W2154457032","https://openalex.org/W2159434269","https://openalex.org/W2160418427","https://openalex.org/W2162578272","https://openalex.org/W2162899067","https://openalex.org/W2168056473","https://openalex.org/W2321791250","https://openalex.org/W2913285263"],"related_works":["https://openalex.org/W2319846447","https://openalex.org/W2322820929","https://openalex.org/W2325458214","https://openalex.org/W7098342683","https://openalex.org/W7212015542","https://openalex.org/W2465930817","https://openalex.org/W2102912801","https://openalex.org/W2023396177","https://openalex.org/W2943200719","https://openalex.org/W2471609321"],"abstract_inverted_index":null,"counts_by_year":[],"updated_date":"2026-07-14T23:32:53.992493","created_date":"2016-06-24T00:00:00"}