{"id":"https://openalex.org/W142028554","doi":null,"title":"[Therapeutic effects of coenzyme Q10 on dilated cardiomyopathy: assessment by 123I-BMIPP myocardial single photon emission computed tomography (SPECT): a multicenter trial in Osaka University Medical School Group].","display_name":"[Therapeutic effects of coenzyme Q10 on dilated cardiomyopathy: assessment by 123I-BMIPP myocardial single photon emission computed tomography (SPECT): a multicenter trial in Osaka University Medical School Group].","publication_year":1996,"publication_date":"1996-01-01","ids":{"openalex":"https://openalex.org/W142028554","mag":"142028554","pmid":"https://pubmed.ncbi.nlm.nih.gov/8819712"},"language":"ja","primary_location":{"id":"pmid:8819712","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8819712","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kaku igaku. The Japanese journal of nuclear medicine","raw_type":"Clinical Trial"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111273167","display_name":"T Nishimura","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I98285908","display_name":"The University of Osaka","ror":"https://ror.org/035t8zc32","country_code":"JP","type":"education","lineage":["https://openalex.org/I98285908"]}],"countries":["JP"],"is_corresponding":false,"raw_author_name":"T Nishimura","raw_affiliation_strings":["Tracer Kinetics and Nuclear Medicine, Osaka University, Japan"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Tracer Kinetics and Nuclear Medicine, Osaka University, Japan","institution_ids":["https://openalex.org/I98285908"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5010809298","display_name":"M Hori","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":false,"raw_author_name":"M Hori","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":2,"citation_normalized_percentile":{"value":0.00506657,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":87,"max":93},"biblio":{"volume":"33","issue":"1","first_page":"27","last_page":"32"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T13012","display_name":"Coenzyme Q10 studies and effects","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T13012","display_name":"Coenzyme Q10 studies and effects","score":0.9897000193595886,"subfield":{"id":"https://openalex.org/subfields/1312","display_name":"Molecular Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T10882","display_name":"Cardiomyopathy and Myosin Studies","score":0.0038999998942017555,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10372","display_name":"Cardiac Imaging and Diagnostics","score":0.002099999925121665,"subfield":{"id":"https://openalex.org/subfields/2741","display_name":"Radiology, Nuclear Medicine and Imaging"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/coenzyme-q10","display_name":"coenzyme Q10","score":0.9980000257492065},{"id":"https://openalex.org/keywords/dilated-cardiomyopathy","display_name":"dilated cardiomyopathy","score":0.9919999837875366},{"id":"https://openalex.org/keywords/123i-bmipp","display_name":"123I-BMIPP","score":0.9539999961853027},{"id":"https://openalex.org/keywords/myocardial-spect","display_name":"myocardial SPECT","score":0.8899999856948853},{"id":"https://openalex.org/keywords/treatment-efficacy-evaluation","display_name":"treatment efficacy assessment","score":0.4830000102519989},{"id":"https://openalex.org/keywords/fractional-shortening","display_name":"fractional shortening","score":0.8529999852180481}],"concepts":[{"id":"https://openalex.org/C2776383484","wikidata":"https://www.wikidata.org/wiki/Q283656","display_name":"Dilated cardiomyopathy","level":3,"score":0.8625291585922241},{"id":"https://openalex.org/C2780441642","wikidata":"https://www.wikidata.org/wiki/Q849737","display_name":"Single-photon emission computed tomography","level":2,"score":0.7987208366394043},{"id":"https://openalex.org/C2779384338","wikidata":"https://www.wikidata.org/wiki/Q321285","display_name":"Coenzyme Q10","level":2,"score":0.765387773513794},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.7480632066726685},{"id":"https://openalex.org/C164705383","wikidata":"https://www.wikidata.org/wiki/Q10379","display_name":"Cardiology","level":1,"score":0.5560890436172485},{"id":"https://openalex.org/C126322002","wikidata":"https://www.wikidata.org/wiki/Q11180","display_name":"Internal medicine","level":1,"score":0.542470395565033},{"id":"https://openalex.org/C2778797674","wikidata":"https://www.wikidata.org/wiki/Q847583","display_name":"Cardiomyopathy","level":3,"score":0.5288969874382019},{"id":"https://openalex.org/C102652120","wikidata":"https://www.wikidata.org/wiki/Q2419430","display_name":"Therapeutic effect","level":2,"score":0.4982278347015381},{"id":"https://openalex.org/C2778064278","wikidata":"https://www.wikidata.org/wiki/Q5372630","display_name":"Emission computed tomography","level":3,"score":0.458883136510849},{"id":"https://openalex.org/C2989005","wikidata":"https://www.wikidata.org/wiki/Q214963","display_name":"Nuclear medicine","level":1,"score":0.4159850478172302},{"id":"https://openalex.org/C126838900","wikidata":"https://www.wikidata.org/wiki/Q77604","display_name":"Radiology","level":1,"score":0.32435619831085205},{"id":"https://openalex.org/C2775842073","wikidata":"https://www.wikidata.org/wiki/Q208376","display_name":"Positron emission tomography","level":2,"score":0.3013972043991089},{"id":"https://openalex.org/C2778198053","wikidata":"https://www.wikidata.org/wiki/Q181754","display_name":"Heart failure","level":2,"score":0.2789425849914551}],"mesh":[{"descriptor_ui":"D000368","descriptor_name":"Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002311","descriptor_name":"Cardiomyopathy, Dilated","qualifier_ui":"Q000000981","qualifier_name":"diagnostic imaging","is_major_topic":true},{"descriptor_ui":"D002311","descriptor_name":"Cardiomyopathy, Dilated","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true},{"descriptor_ui":"D003067","descriptor_name":"Coenzymes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D005227","descriptor_name":"Fatty Acids","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D005260","descriptor_name":"Female","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D007457","descriptor_name":"Iodine Radioisotopes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007462","descriptor_name":"Iodobenzenes","qualifier_ui":null,"qualifier_name":null,"is_major_topic":true},{"descriptor_ui":"D007564","descriptor_name":"Japan","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008875","descriptor_name":"Middle Aged","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D014451","descriptor_name":"Ubiquinone","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D014451","descriptor_name":"Ubiquinone","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D015899","descriptor_name":"Tomography, Emission-Computed, Single-Photon","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":3,"locations":[{"id":"pmid:8819712","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8819712","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Kaku igaku. The Japanese journal of nuclear medicine","raw_type":"Clinical Trial"},{"id":"mag:142028554","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/8819712","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null},{"id":"mag:398859746","doi":null,"is_oa":false,"landing_page_url":"http://ci.nii.ac.jp/naid/10008421200","pdf_url":null,"source":{"id":"https://openalex.org/S4306552713","display_name":"\u6838\u533b\u5b66","issn_l":"0022-7854","issn":["0022-7854"],"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":["medline","poland-20","russia-white-list-4"],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"journal"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"\u6838\u533b\u5b66","raw_type":null}],"best_oa_location":null,"sustainable_development_goals":[{"display_name":"Good health and well-being","id":"https://metadata.un.org/sdg/3","score":0.98580002784729}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W2072744430","https://openalex.org/W3140012863","https://openalex.org/W4235027532","https://openalex.org/W2416469212","https://openalex.org/W2277314592","https://openalex.org/W2384232671","https://openalex.org/W6999281540","https://openalex.org/W1972830562","https://openalex.org/W398859746","https://openalex.org/W2352853389"],"abstract_inverted_index":{"To":[0],"evaluate":[1,95],"therapeutic":[2,97],"effects":[3,98],"of":[4,68,99,109],"Cenzyme":[5],"Q10":[6],"(CoQ10),":[7],"15":[8],"patients":[9,67],"with":[10,44],"dilated":[11,69,110],"cardiomyopathy":[12],"were":[13],"investigated":[14],"by":[15,31],"123I-BMIPP":[16,86],"myocardial":[17,87,103],"single":[18],"photon":[19],"emission":[20],"computed":[21],"tomography":[22],"(SPECT).":[23],"The":[24],"BMIPP":[25,41],"defect":[26,42],"score":[27,43],"was":[28,47,76,89],"determined":[29],"semiquantitatively":[30],"using":[32,74],"representative":[33],"short":[34],"and":[35,80],"long":[36],"axial":[37],"SPECT":[38,88],"images.":[39],"Mean":[40],"CoQ10":[45,59,82],"treatment":[46],"significantly":[48],"low,":[49],"7.7":[50],"+/-":[51,56],"6.1":[52],"compared":[53],"to":[54,91,94],"12.7":[55],"7.4":[57],"without":[58],"treatment.":[60,83],"On":[61],"the":[62,96,107],"other":[63],"hand,":[64],"in":[65,106],"8":[66],"cardiomyopathy,":[70],"%":[71],"fractional":[72],"shortening":[73],"echocardiography":[75],"not":[77],"different":[78],"before":[79],"after":[81],"In":[84],"conclusion,":[85],"proved":[90],"be":[92],"sensitive":[93],"CoQ10,":[100],"which":[101],"improve":[102],"mitochondrial":[104],"function,":[105],"cases":[108],"cardiomyopathy.":[111]},"counts_by_year":[{"year":2021,"cited_by_count":1},{"year":2013,"cited_by_count":1}],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}