{"id":"https://openalex.org/W141547775","doi":"https://doi.org/10.1007/978-0-387-33504-9_3","title":"Cysteamine Dioxygenase: Evidence for the Physiological Conversion of Cysteamine to Hypotaurine in Rat and Mouse Tissues","display_name":"Cysteamine Dioxygenase: Evidence for the Physiological Conversion of Cysteamine to Hypotaurine in Rat and Mouse Tissues","publication_year":2006,"publication_date":"2006-09-30","ids":{"openalex":"https://openalex.org/W141547775","doi":"https://doi.org/10.1007/978-0-387-33504-9_3","mag":"141547775","pmid":"https://pubmed.ncbi.nlm.nih.gov/17153586"},"language":"en","primary_location":{"id":"doi:10.1007/978-0-387-33504-9_3","doi":"https://doi.org/10.1007/978-0-387-33504-9_3","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-0-387-33504-9_3","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Experimental Medicine and Biology","raw_type":"book-chapter"},"volume":{"id":"https://openalex.org/W4251431296","display_name":"Taurine 6"},"type":"book-chapter","indexed_in":["crossref","pubmed"],"open_access":{"is_oa":false,"oa_status":"closed","oa_url":null,"any_repository_has_fulltext":false},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5111581329","display_name":"Relicardo M. Coloso","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Relicardo M. Coloso","raw_affiliation_strings":["Cornell University, Division of Nutritional Sciences, Ithaca, New York 148453, USA","Cornell University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Cornell University, Division of Nutritional Sciences, Ithaca, New York 148453, USA","institution_ids":["https://openalex.org/I205783295"]},{"raw_affiliation_string":"Cornell University","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5044221811","display_name":"Lawrence L. Hirschberger","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Lawrence L. Hirschberger","raw_affiliation_strings":["Division of Nutritional Sciences, Cornell University, Ithaca, USA","Cornell University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nutritional Sciences, Cornell University, Ithaca, USA","institution_ids":["https://openalex.org/I205783295"]},{"raw_affiliation_string":"Cornell University","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5005492969","display_name":"John E. Dominy","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"John E. Dominy","raw_affiliation_strings":["Division of Nutritional Sciences, Cornell University, Ithaca, USA","Cornell University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nutritional Sciences, Cornell University, Ithaca, USA","institution_ids":["https://openalex.org/I205783295"]},{"raw_affiliation_string":"Cornell University","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"middle","author":{"id":"https://openalex.org/A5109513950","display_name":"Jeong-In Lee","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Jeong-In Lee","raw_affiliation_strings":["Division of Nutritional Sciences, Cornell University, Ithaca, USA","Cornell University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nutritional Sciences, Cornell University, Ithaca, USA","institution_ids":["https://openalex.org/I205783295"]},{"raw_affiliation_string":"Cornell University","institution_ids":["https://openalex.org/I205783295"]}]},{"author_position":"last","author":{"id":"https://openalex.org/A5091381979","display_name":"Martha H. Stipanuk","orcid":null,"observed_orcids":[]},"institutions":[{"id":"https://openalex.org/I205783295","display_name":"Cornell University","ror":"https://ror.org/05bnh6r87","country_code":"US","type":"education","lineage":["https://openalex.org/I205783295"]}],"countries":["US"],"is_corresponding":false,"raw_author_name":"Martha H. Stipanuk","raw_affiliation_strings":["Division of Nutritional Sciences, Cornell University, Ithaca, USA","Cornell University"],"raw_orcid":null,"affiliations":[{"raw_affiliation_string":"Division of Nutritional Sciences, Cornell University, Ithaca, USA","institution_ids":["https://openalex.org/I205783295"]},{"raw_affiliation_string":"Cornell University","institution_ids":["https://openalex.org/I205783295"]}]}],"institutions":[],"countries_distinct_count":1,"institutions_distinct_count":1,"corresponding_author_ids":[],"corresponding_institution_ids":["https://openalex.org/I205783295"],"apc_list":null,"apc_paid":null,"fwci":5.9261,"has_fulltext":false,"cited_by_count":60,"citation_normalized_percentile":{"value":0.95629553,"is_in_top_1_percent":false,"is_in_top_10_percent":true},"cited_by_percentile_year":{"min":88,"max":98},"biblio":{"volume":"583","issue":null,"first_page":"25","last_page":"36"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T12533","display_name":"Aldose Reductase and Taurine","score":0.9574999809265137,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},"topics":[{"id":"https://openalex.org/T12533","display_name":"Aldose Reductase and Taurine","score":0.9574999809265137,"subfield":{"id":"https://openalex.org/subfields/1307","display_name":"Cell Biology"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T11481","display_name":"Sulfur Compounds in Biology","score":0.02969999983906746,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}},{"id":"https://openalex.org/T12770","display_name":"Amino Acid Enzymes and Metabolism","score":0.004600000102072954,"subfield":{"id":"https://openalex.org/subfields/1303","display_name":"Biochemistry"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/cysteamine","display_name":"cysteamine","score":0.9670000076293945},{"id":"https://openalex.org/keywords/hypotaurine","display_name":"hypotaurine","score":0.9980000257492065},{"id":"https://openalex.org/keywords/sulfur-metabolism","display_name":"sulfur metabolism","score":0.48500001430511475},{"id":"https://openalex.org/keywords/rats","display_name":"rats","score":0.3659999966621399},{"id":"https://openalex.org/keywords/mouse-tissues","display_name":"mouse tissues","score":0.7129999995231628}],"concepts":[{"id":"https://openalex.org/C2776609658","wikidata":"https://www.wikidata.org/wiki/Q617563","display_name":"Cysteamine","level":2,"score":0.9695353507995605},{"id":"https://openalex.org/C2776853492","wikidata":"https://www.wikidata.org/wiki/Q3138539","display_name":"Hypotaurine","level":4,"score":0.9691789746284485},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.6188951134681702},{"id":"https://openalex.org/C2779701627","wikidata":"https://www.wikidata.org/wiki/Q207051","display_name":"Taurine","level":3,"score":0.410917192697525},{"id":"https://openalex.org/C55493867","wikidata":"https://www.wikidata.org/wiki/Q7094","display_name":"Biochemistry","level":1,"score":0.38867083191871643},{"id":"https://openalex.org/C98274493","wikidata":"https://www.wikidata.org/wiki/Q128406","display_name":"Pharmacology","level":1,"score":0.3375527560710907},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.2238495647907257},{"id":"https://openalex.org/C515207424","wikidata":"https://www.wikidata.org/wiki/Q8066","display_name":"Amino acid","level":2,"score":0.0}],"mesh":[{"descriptor_ui":"D000581","descriptor_name":"Amidohydrolases","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D000818","descriptor_name":"Animals","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D002851","descriptor_name":"Chromatography, High Pressure Liquid","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D003543","descriptor_name":"Cysteamine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D004032","descriptor_name":"Diet","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D004044","descriptor_name":"Dietary Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008297","descriptor_name":"Male","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D008810","descriptor_name":"Mice, Inbred C57BL","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D011897","descriptor_name":"Random Allocation","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013654","descriptor_name":"Taurine","qualifier_ui":"Q000031","qualifier_name":"analogs & derivatives","is_major_topic":true},{"descriptor_ui":"D013654","descriptor_name":"Taurine","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D014018","descriptor_name":"Tissue Distribution","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D015815","descriptor_name":"Cell Adhesion Molecules","qualifier_ui":"Q000235","qualifier_name":"genetics","is_major_topic":false},{"descriptor_ui":"D015815","descriptor_name":"Cell Adhesion Molecules","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":false},{"descriptor_ui":"D017207","descriptor_name":"Rats, Sprague-Dawley","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D018345","descriptor_name":"Mice, Knockout","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D049308","descriptor_name":"Dioxygenases","qualifier_ui":"Q000378","qualifier_name":"metabolism","is_major_topic":true},{"descriptor_ui":"D051379","descriptor_name":"Mice","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D051381","descriptor_name":"Rats","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D058851","descriptor_name":"GPI-Linked Proteins","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false}],"locations_count":2,"locations":[{"id":"doi:10.1007/978-0-387-33504-9_3","doi":"https://doi.org/10.1007/978-0-387-33504-9_3","is_oa":false,"landing_page_url":"https://doi.org/10.1007/978-0-387-33504-9_3","pdf_url":null,"source":{"id":"https://openalex.org/S4306463937","display_name":"Springer eBooks","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/P4310319965","host_organization_name":"Springer Nature","host_organization_lineage":["https://openalex.org/P4310319965"],"host_organization_lineage_names":["Springer Nature"],"type":"ebook platform"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in Experimental Medicine and Biology","raw_type":"book-chapter"},{"id":"pmid:17153586","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/17153586","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"Advances in experimental medicine and biology","raw_type":"Journal Article"}],"best_oa_location":null,"sustainable_development_goals":[],"study_designs":[],"awards":[{"id":"https://openalex.org/G4188424205","display_name":null,"funder_award_id":"DK-056649","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"},{"id":"https://openalex.org/G4311725061","display_name":"Nutritional Regulation of Cysteine Dioxygenase","funder_award_id":"R01DK056649","funder_id":"https://openalex.org/F4320337357","funder_display_name":"National Institute of Diabetes and Digestive and Kidney Diseases"}],"funders":[{"id":"https://openalex.org/F4320337357","display_name":"National Institute of Diabetes and Digestive and Kidney Diseases","ror":"https://ror.org/00adh9b73"}],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":26,"referenced_works":["https://openalex.org/W12258903","https://openalex.org/W35122594","https://openalex.org/W56310818","https://openalex.org/W102309723","https://openalex.org/W1492918724","https://openalex.org/W1518778430","https://openalex.org/W1552307680","https://openalex.org/W1561815023","https://openalex.org/W1964929962","https://openalex.org/W1979087975","https://openalex.org/W2024338092","https://openalex.org/W2029055174","https://openalex.org/W2047517357","https://openalex.org/W2062181273","https://openalex.org/W2062403748","https://openalex.org/W2063968553","https://openalex.org/W2121264215","https://openalex.org/W2154084777","https://openalex.org/W2168550816","https://openalex.org/W2179515218","https://openalex.org/W2284496186","https://openalex.org/W2410103033","https://openalex.org/W2418051430","https://openalex.org/W2425663546","https://openalex.org/W4232534952","https://openalex.org/W4246904413"],"related_works":["https://openalex.org/W2314442027","https://openalex.org/W2425663546","https://openalex.org/W2413980964","https://openalex.org/W2394994697","https://openalex.org/W1577114229","https://openalex.org/W2207868798","https://openalex.org/W2419599941","https://openalex.org/W2421771231","https://openalex.org/W4234202081","https://openalex.org/W317506201"],"abstract_inverted_index":null,"counts_by_year":[{"year":2026,"cited_by_count":2},{"year":2025,"cited_by_count":3},{"year":2024,"cited_by_count":3},{"year":2023,"cited_by_count":3},{"year":2022,"cited_by_count":3},{"year":2021,"cited_by_count":1},{"year":2020,"cited_by_count":3},{"year":2019,"cited_by_count":4},{"year":2018,"cited_by_count":2},{"year":2017,"cited_by_count":2},{"year":2016,"cited_by_count":5},{"year":2015,"cited_by_count":2},{"year":2014,"cited_by_count":5},{"year":2013,"cited_by_count":5},{"year":2012,"cited_by_count":1}],"updated_date":"2026-10-31T12:09:11.096373","created_date":"2016-06-24T00:00:00"}