{"id":"https://openalex.org/W140059989","doi":null,"title":"Markov chain decomposition and characterization of hypertensive blood pressure with applications to linkage analysis","display_name":"Markov chain decomposition and characterization of hypertensive blood pressure with applications to linkage analysis","publication_year":2005,"publication_date":"2005-01-01","ids":{"openalex":"https://openalex.org/W140059989","mag":"140059989"},"language":"en","primary_location":{"id":"pmh:oai:epublications.marquette.edu:dissertations-2851","doi":null,"is_oa":false,"landing_page_url":"https://epublications.marquette.edu/dissertations/AAI3201933","pdf_url":null,"source":{"id":"https://openalex.org/S4306401682","display_name":"e-Publications@Marquette (Marquette University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I102461120","host_organization_name":"Marquette University","host_organization_lineage":["https://openalex.org/I102461120"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Dissertations (1962 - 2010) Access via Proquest Digital Dissertations","raw_type":"text"},"volume":null,"type":"dissertation","indexed_in":[],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"http://hdl.handle.net/10525/4322","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5113722674","display_name":"Roumyana Yordanova","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"Roumyana Yordanova","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5113722674"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":null,"has_fulltext":false,"cited_by_count":0,"citation_normalized_percentile":null,"cited_by_percentile_year":null,"biblio":{"volume":null,"issue":null,"first_page":null,"last_page":null},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.9550999999046326,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10144","display_name":"Blood Pressure and Hypertension Studies","score":0.9550999999046326,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10745","display_name":"Heart Rate Variability and Autonomic Control","score":0.011800000444054604,"subfield":{"id":"https://openalex.org/subfields/2705","display_name":"Cardiology and Cardiovascular Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10261","display_name":"Genetic Associations and Epidemiology","score":0.006099999882280827,"subfield":{"id":"https://openalex.org/subfields/1311","display_name":"Genetics"},"field":{"id":"https://openalex.org/fields/13","display_name":"Biochemistry, Genetics and Molecular Biology"},"domain":{"id":"https://openalex.org/domains/1","display_name":"Life Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/markov-chain-decomposition","display_name":"Markov chain decomposition","score":0.9710000157356262},{"id":"https://openalex.org/keywords/spectral-gap","display_name":"spectral gap","score":0.765999972820282},{"id":"https://openalex.org/keywords/convergence-rate-bounds","display_name":"convergence rate bounds","score":0.8100000023841858},{"id":"https://openalex.org/keywords/renin-angiotensin-system","display_name":"renin-angiotensin system","score":0.9850000143051147},{"id":"https://openalex.org/keywords/linkage-analysis","display_name":"linkage analysis","score":0.6779999732971191},{"id":"https://openalex.org/keywords/qtl-mapping","display_name":"QTL mapping","score":0.8009999990463257},{"id":"https://openalex.org/keywords/principal-components","display_name":"principal components","score":0.5260000228881836},{"id":"https://openalex.org/keywords/central-limit-theorem","display_name":"central limit theorem","score":0.7009999752044678},{"id":"https://openalex.org/keywords/heritability","display_name":"heritability","score":0.7369999885559082},{"id":"https://openalex.org/keywords/rats","display_name":"rats","score":0.3790000081062317},{"id":"https://openalex.org/keywords/human","display_name":"human","score":0.7099999785423279}],"concepts":[{"id":"https://openalex.org/C98763669","wikidata":"https://www.wikidata.org/wiki/Q176645","display_name":"Markov chain","level":2,"score":0.6466299295425415},{"id":"https://openalex.org/C31266012","wikidata":"https://www.wikidata.org/wiki/Q6554340","display_name":"Linkage (software)","level":3,"score":0.5085772275924683},{"id":"https://openalex.org/C124681953","wikidata":"https://www.wikidata.org/wiki/Q339062","display_name":"Decomposition","level":2,"score":0.46005743741989136},{"id":"https://openalex.org/C2780841128","wikidata":"https://www.wikidata.org/wiki/Q5073781","display_name":"Characterization (materials science)","level":2,"score":0.4456873834133148},{"id":"https://openalex.org/C41008148","wikidata":"https://www.wikidata.org/wiki/Q21198","display_name":"Computer science","level":0,"score":0.4152153730392456},{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.34908080101013184},{"id":"https://openalex.org/C185592680","wikidata":"https://www.wikidata.org/wiki/Q2329","display_name":"Chemistry","level":0,"score":0.16199538111686707},{"id":"https://openalex.org/C54355233","wikidata":"https://www.wikidata.org/wiki/Q7162","display_name":"Genetics","level":1,"score":0.16003167629241943},{"id":"https://openalex.org/C192562407","wikidata":"https://www.wikidata.org/wiki/Q228736","display_name":"Materials science","level":0,"score":0.15044012665748596},{"id":"https://openalex.org/C86803240","wikidata":"https://www.wikidata.org/wiki/Q420","display_name":"Biology","level":0,"score":0.1234951913356781},{"id":"https://openalex.org/C119857082","wikidata":"https://www.wikidata.org/wiki/Q2539","display_name":"Machine learning","level":1,"score":0.12100973725318909},{"id":"https://openalex.org/C171250308","wikidata":"https://www.wikidata.org/wiki/Q11468","display_name":"Nanotechnology","level":1,"score":0.07810130715370178},{"id":"https://openalex.org/C104317684","wikidata":"https://www.wikidata.org/wiki/Q7187","display_name":"Gene","level":2,"score":0.07640007138252258},{"id":"https://openalex.org/C178790620","wikidata":"https://www.wikidata.org/wiki/Q11351","display_name":"Organic chemistry","level":1,"score":0.0}],"mesh":[],"locations_count":5,"locations":[{"id":"pmh:oai:epublications.marquette.edu:dissertations-2851","doi":null,"is_oa":false,"landing_page_url":"https://epublications.marquette.edu/dissertations/AAI3201933","pdf_url":null,"source":{"id":"https://openalex.org/S4306401682","display_name":"e-Publications@Marquette (Marquette University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I102461120","host_organization_name":"Marquette University","host_organization_lineage":["https://openalex.org/I102461120"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Dissertations (1962 - 2010) Access via Proquest Digital Dissertations","raw_type":"text"},{"id":"pmh:oai:epublications.marquette.edu:dissertations_mu-2898","doi":null,"is_oa":false,"landing_page_url":"https://epublications.marquette.edu/dissertations_mu/1885","pdf_url":null,"source":{"id":"https://openalex.org/S4306401682","display_name":"e-Publications@Marquette (Marquette University)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I102461120","host_organization_name":"Marquette University","host_organization_lineage":["https://openalex.org/I102461120"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"Dissertations (1934 -)","raw_type":"text"},{"id":"pmh:oai:bpos.bg:75285","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10525/4322","pdf_url":null,"source":{"id":"https://openalex.org/S7407055231","display_name":"Bulgarian Portal for Open Science","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"thesis"},{"id":"pmh:oai:sci-gems.math.bas.bg:10525/4322","doi":null,"is_oa":false,"landing_page_url":"http://hdl.handle.net/10525/4322","pdf_url":null,"source":{"id":"https://openalex.org/S4306401343","display_name":"Bulgarian Digital Mathematics Library (BulDML) at IMI-BAS (Institute of Mathematics and Informatics)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I4210105926","host_organization_name":"Institute of Mathematics and Informatics","host_organization_lineage":["https://openalex.org/I4210105926"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"","raw_type":"Dissertation"},{"id":"mag:140059989","doi":null,"is_oa":false,"landing_page_url":"http://epublications.marquette.edu/cgi/viewcontent.cgi?article=2851&context=dissertations","pdf_url":null,"source":null,"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":null}],"best_oa_location":{"id":"pmh:oai:bpos.bg:75285","doi":null,"is_oa":true,"landing_page_url":"http://hdl.handle.net/10525/4322","pdf_url":null,"source":{"id":"https://openalex.org/S7407055231","display_name":"Bulgarian Portal for Open Science","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":null,"host_organization_name":null,"host_organization_lineage":[],"host_organization_lineage_names":[],"type":"repository"},"license":"other-oa","license_id":"https://openalex.org/licenses/other-oa","version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":null,"raw_type":"thesis"},"sustainable_development_goals":[{"score":0.4043000042438507,"id":"https://metadata.un.org/sdg/3","display_name":"Good health and well-being"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":0,"referenced_works":[],"related_works":["https://openalex.org/W7058215128","https://openalex.org/W2289025122","https://openalex.org/W2127120893","https://openalex.org/W2146044479","https://openalex.org/W2154823201","https://openalex.org/W2066163068","https://openalex.org/W2070839347","https://openalex.org/W2126109643","https://openalex.org/W7095652131","https://openalex.org/W2328401898"],"abstract_inverted_index":{"This":[0],"thesis":[1],"uses":[2],"Markov":[3],"chain":[4,117],"decomposition":[5,121],"techniques":[6],"to":[7,89,130,142],"extract":[8],"informative":[9],"traits":[10],"from":[11],"arterial":[12],"pressure":[13,33],"recordings":[14,77],"of":[15,40,45,50,68,76,81,115,146],"hypertensive":[16,96],"rats":[17],"and":[18,26,43,53,78,95,98,106,125,148,160],"humans.":[19,163],"The":[20,63],"feedback":[21],"mechanisms,":[22],"such":[23],"as":[24],"baroreceptor":[25],"renin":[27],"angiotensin":[28],"system,":[29],"acting":[30],"on":[31,71],"blood":[32,46],"are":[34,56,87,118,128,140,158],"quantified":[35],"by":[36],"the":[37,66,69,72,82,101,110,116,134,144,150,156],"Cheeger":[38,51,136],"ratios":[39,52],"specific":[41],"levels":[42],"patterns":[44],"pressure.":[47],"Statistical":[48],"properties":[49],"related":[54],"quantities":[55,86],"established":[57],"in":[58],"a":[59],"central":[60],"limit":[61],"theorem.":[62],"results":[64],"show":[65],"dependence":[67],"error":[70],"spectral":[73],"gap,":[74],"length":[75],"relative":[79],"frequencies":[80],"estimated":[83,135],"sets.":[84],"These":[85],"shown":[88],"be":[90],"statistically":[91],"different":[92],"between":[93],"normal":[94],"rats,":[97],"heritable":[99],"for":[100,109,133,154,162],"human":[102],"population.":[103],"New":[104],"lower":[105],"upper":[107],"bounds":[108],"convergence":[111],"rate":[112],"(spectral":[113],"gap)":[114],"derived":[119,159],"via":[120],"techniques.":[122],"Linkage":[123],"analysis":[124],"multi-trait":[126],"linkage":[127,151],"used":[129,141],"find":[131],"QTL":[132],"ratios.":[137],"Principal":[138],"components":[139],"reduce":[143],"number":[145],"tests":[147],"increase":[149],"power.":[152],"Conditions":[153],"maximizing":[155],"power":[157],"applied":[161]},"counts_by_year":[],"updated_date":"2026-11-04T10:54:05.112534","created_date":"2016-06-24T00:00:00"}