{"id":"https://openalex.org/W137962260","doi":null,"title":"Optimizing the duration of anticoagulation therapy for venous thrombosis.","display_name":"Optimizing the duration of anticoagulation therapy for venous thrombosis.","publication_year":1999,"publication_date":"1999-05-04","ids":{"openalex":"https://openalex.org/W137962260","mag":"137962260","pmid":"https://pubmed.ncbi.nlm.nih.gov/10333836","pmcid":"https://www.ncbi.nlm.nih.gov/pmc/articles/1230316"},"language":"en","primary_location":{"id":"pmh:oai:europepmc.org:216372","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1230316","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"volume":null,"type":"article","is_traditional":true,"indexed_in":["pubmed"],"open_access":{"is_oa":true,"oa_status":"green","oa_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1230316","any_repository_has_fulltext":true},"authorships":[{"author_position":"first","author":{"id":"https://openalex.org/A5107886979","display_name":"Susan Solymoss","orcid":null,"observed_orcids":[]},"institutions":[],"countries":[],"is_corresponding":true,"raw_author_name":"S Solymoss","raw_affiliation_strings":[],"raw_orcid":null,"affiliations":[]}],"institutions":[],"countries_distinct_count":0,"institutions_distinct_count":0,"corresponding_author_ids":["https://openalex.org/A5107886979"],"corresponding_institution_ids":[],"apc_list":null,"apc_paid":null,"fwci":0.0,"has_fulltext":false,"cited_by_count":3,"citation_normalized_percentile":{"value":0.0,"is_in_top_1_percent":false,"is_in_top_10_percent":false},"cited_by_percentile_year":{"min":88,"max":93},"biblio":{"volume":"160","issue":"9","first_page":"1317","last_page":"8"},"is_retracted":false,"is_paratext":false,"is_xpac":false,"primary_topic":{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},"topics":[{"id":"https://openalex.org/T10285","display_name":"Venous Thromboembolism Diagnosis and Management","score":1.0,"subfield":{"id":"https://openalex.org/subfields/2724","display_name":"Internal Medicine"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T10881","display_name":"Blood Coagulation and Thrombosis Mechanisms","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2720","display_name":"Hematology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}},{"id":"https://openalex.org/T11929","display_name":"Cerebral Venous Sinus Thrombosis","score":0.0,"subfield":{"id":"https://openalex.org/subfields/2728","display_name":"Clinical Neurology"},"field":{"id":"https://openalex.org/fields/27","display_name":"Medicine"},"domain":{"id":"https://openalex.org/domains/4","display_name":"Health Sciences"}}],"keywords":[{"id":"https://openalex.org/keywords/venous-thromboembolism","display_name":"venous thromboembolism","score":0.8669999837875366},{"id":"https://openalex.org/keywords/duration-of-anticoagulation","display_name":"anticoagulation duration","score":0.8730000257492065},{"id":"https://openalex.org/keywords/deep-vein-thrombosis","display_name":"deep vein thrombosis","score":0.9679999947547913},{"id":"https://openalex.org/keywords/pulmonary-embolism","display_name":"pulmonary embolism","score":1.0},{"id":"https://openalex.org/keywords/low-molecular-weight-heparin","display_name":"low molecular weight heparin","score":0.8370000123977661},{"id":"https://openalex.org/keywords/unfractionated-heparin","display_name":"unfractionated heparin","score":0.9869999885559082},{"id":"https://openalex.org/keywords/recurrent-thromboembolism","display_name":"recurrent thromboembolism","score":0.828000009059906},{"id":"https://openalex.org/keywords/bleeding-risk","display_name":"bleeding risk","score":0.9869999885559082},{"id":"https://openalex.org/keywords/long-term-anticoagulation","display_name":"long-term anticoagulation","score":0.871999979019165},{"id":"https://openalex.org/keywords/cancer-associated-thrombosis","display_name":"cancer-associated thrombosis","score":0.7689999938011169}],"concepts":[{"id":"https://openalex.org/C71924100","wikidata":"https://www.wikidata.org/wiki/Q11190","display_name":"Medicine","level":0,"score":0.8683605194091797},{"id":"https://openalex.org/C2776265017","wikidata":"https://www.wikidata.org/wiki/Q220570","display_name":"Pulmonary embolism","level":2,"score":0.7139875292778015},{"id":"https://openalex.org/C2780868729","wikidata":"https://www.wikidata.org/wiki/Q261327","display_name":"Thrombosis","level":2,"score":0.65828537940979},{"id":"https://openalex.org/C2993316766","wikidata":"https://www.wikidata.org/wiki/Q215118","display_name":"Anticoagulant therapy","level":2,"score":0.6171958446502686},{"id":"https://openalex.org/C2778959117","wikidata":"https://www.wikidata.org/wiki/Q430892","display_name":"Deep vein","level":3,"score":0.5702642202377319},{"id":"https://openalex.org/C2777557582","wikidata":"https://www.wikidata.org/wiki/Q190016","display_name":"Heparin","level":2,"score":0.5307303071022034},{"id":"https://openalex.org/C177713679","wikidata":"https://www.wikidata.org/wiki/Q679690","display_name":"Intensive care medicine","level":1,"score":0.47817665338516235},{"id":"https://openalex.org/C2780011451","wikidata":"https://www.wikidata.org/wiki/Q2751330","display_name":"Venous thrombosis","level":3,"score":0.4708121716976166},{"id":"https://openalex.org/C112758219","wikidata":"https://www.wikidata.org/wiki/Q16038819","display_name":"Duration (music)","level":2,"score":0.4322744905948639},{"id":"https://openalex.org/C141071460","wikidata":"https://www.wikidata.org/wiki/Q40821","display_name":"Surgery","level":1,"score":0.4298984110355377},{"id":"https://openalex.org/C2991741193","wikidata":"https://www.wikidata.org/wiki/Q2751330","display_name":"Venous thromboembolism","level":3,"score":0.4155377447605133},{"id":"https://openalex.org/C124952713","wikidata":"https://www.wikidata.org/wiki/Q8242","display_name":"Literature","level":1,"score":0.0},{"id":"https://openalex.org/C142362112","wikidata":"https://www.wikidata.org/wiki/Q735","display_name":"Art","level":0,"score":0.0}],"mesh":[{"descriptor_ui":"D000925","descriptor_name":"Anticoagulants","qualifier_ui":"Q000008","qualifier_name":"administration & dosage","is_major_topic":true},{"descriptor_ui":"D000925","descriptor_name":"Anticoagulants","qualifier_ui":"Q000009","qualifier_name":"adverse effects","is_major_topic":false},{"descriptor_ui":"D000925","descriptor_name":"Anticoagulants","qualifier_ui":"Q000627","qualifier_name":"therapeutic use","is_major_topic":false},{"descriptor_ui":"D006470","descriptor_name":"Hemorrhage","qualifier_ui":"Q000209","qualifier_name":"etiology","is_major_topic":false},{"descriptor_ui":"D006801","descriptor_name":"Humans","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012008","descriptor_name":"Recurrence","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D012307","descriptor_name":"Risk Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D013997","descriptor_name":"Time Factors","qualifier_ui":null,"qualifier_name":null,"is_major_topic":false},{"descriptor_ui":"D020246","descriptor_name":"Venous Thrombosis","qualifier_ui":"Q000188","qualifier_name":"drug therapy","is_major_topic":true}],"locations_count":5,"locations":[{"id":"pmh:oai:europepmc.org:216372","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1230316","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},{"id":"pmid:10333836","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10333836","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne","raw_type":"Editorial"},{"id":"pmh:oai:pubmedcentral.nih.gov:1230316","doi":null,"is_oa":true,"landing_page_url":"https://pmc.ncbi.nlm.nih.gov/articles/PMC1230316/","pdf_url":null,"source":{"id":"https://openalex.org/S2764455111","display_name":"PubMed Central","issn_l":null,"issn":null,"is_oa":true,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":"CMAJ","raw_type":"Text"},{"id":"pmh:oai:CiteSeerX.psu:10.1.1.545.7847","doi":null,"is_oa":false,"landing_page_url":"http://citeseerx.ist.psu.edu/viewdoc/summary?doi=10.1.1.545.7847","pdf_url":null,"source":null,"license":null,"license_id":null,"version":"submittedVersion","is_accepted":false,"is_published":false,"raw_source_name":"http://www.cmaj.ca/content/160/9/1317.full.pdf","raw_type":"text"},{"id":"mag:137962260","doi":null,"is_oa":false,"landing_page_url":"https://pubmed.ncbi.nlm.nih.gov/10333836","pdf_url":null,"source":{"id":"https://openalex.org/S4306525036","display_name":"PubMed","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1299303238","host_organization_name":"National Institutes of Health","host_organization_lineage":["https://openalex.org/I1299303238"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":null,"is_accepted":false,"is_published":false,"raw_source_name":"PubMed","raw_type":null}],"best_oa_location":{"id":"pmh:oai:europepmc.org:216372","doi":null,"is_oa":true,"landing_page_url":"https://www.ncbi.nlm.nih.gov/pmc/articles/1230316","pdf_url":null,"source":{"id":"https://openalex.org/S4306400806","display_name":"Europe PMC (PubMed Central)","issn_l":null,"issn":null,"is_oa":false,"is_in_doaj":false,"is_core":false,"listed_in":[],"host_organization":"https://openalex.org/I1303153112","host_organization_name":"European Bioinformatics Institute","host_organization_lineage":["https://openalex.org/I1303153112"],"host_organization_lineage_names":[],"type":"repository"},"license":null,"license_id":null,"version":"publishedVersion","is_accepted":true,"is_published":true,"raw_source_name":null,"raw_type":"Text"},"sustainable_development_goals":[{"display_name":"Good health and well-being","score":1.0,"id":"https://metadata.un.org/sdg/3"}],"study_designs":[],"awards":[],"funders":[],"has_content":{"grobid_xml":false,"pdf":false},"content_urls":null,"referenced_works_count":10,"referenced_works":["https://openalex.org/W1965685439","https://openalex.org/W2012519169","https://openalex.org/W2089337151","https://openalex.org/W2140640148","https://openalex.org/W2152900444","https://openalex.org/W2327974959","https://openalex.org/W2331935930","https://openalex.org/W2332640098","https://openalex.org/W2340351677","https://openalex.org/W2398329788"],"related_works":["https://openalex.org/W7099431642","https://openalex.org/W2316645030","https://openalex.org/W4386816798","https://openalex.org/W95386903","https://openalex.org/W3210630559","https://openalex.org/W193445203","https://openalex.org/W2049601701","https://openalex.org/W2133126978","https://openalex.org/W7100565725","https://openalex.org/W4236205806"],"abstract_inverted_index":{"Clinical":[0],"research":[1],"on":[2],"venous":[3],"thromboembolism":[4,66,106],"hashelped":[5],"to":[6,24,27,43,95,114],"optimize":[7],"the":[8,45,59,63,69,78,83,102],"diagnosis":[9],"and":[10,15],"managementof":[11],"deep":[12],"vein":[13],"thrombosis":[14],"pulmonary":[16],"embolism.":[17],"Clear":[18],"concepts":[19],"are":[20,89],"emerging":[21,98],"with":[22,31,129],"respect":[23],"how":[25],"best":[26],"provide":[28],"initial":[29],"therapy":[30,50,84],"unfractionated,":[32],"or":[33],"low-molecu-lar-weight,":[34],"heparin.":[35],"A":[36],"number":[37],"of":[38,48,61,65,80,104,122],"studies":[39],"have":[40],"also":[41],"at-tempted":[42],"establish":[44],"optimal":[46],"duration":[47],"anticoagula-tion":[49],"in":[51,110,127],"patients":[52,128],"without":[53],"concurrent":[54],"malignant":[55,132],"disease.":[56],"In":[57],"determining":[58],"length":[60],"treatment,":[62],"risk":[64,79,103,121],"recurring":[67],"once":[68],"anticoagulant":[70],"ther-apy":[71],"is":[72,85,107,124],"stopped":[73],"must":[74],"be":[75],"weighed":[76],"against":[77],"bleeding":[81],"if":[82],"continued.":[86],"Although":[87],"there":[88],"no":[90],"definitive":[91],"guidelines":[92],"that":[93,101],"apply":[94],"all":[96],"patients,":[97],"evidence":[99],"suggests":[100],"recurrent":[105],"suf-ficiently":[108],"high":[109,120],"some":[111],"patient":[112],"groups":[113],"favour":[115],"extended":[116],"anticoagulation":[117],"therapy.":[118],"This":[119],"recurrence":[123],"well":[125],"known":[126],"an":[130],"underlying":[131],"dis-":[133]},"counts_by_year":[{"year":2014,"cited_by_count":1}],"updated_date":"2026-11-10T11:39:43.021295","created_date":"2016-06-24T00:00:00"}